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Dataset results
816 results for “Spleen”
Spleen Volume Change Predicts 45-Day Mortality in Neurocritical Care: A Prospective Cohort Study
ClinicalTrials.gov study NCT07132996. IPD Sharing: YES. Countries: 1. Publications: 0.
Spleen Size in Peripheral Blood Stem Cell Donors
ClinicalTrials.gov study NCT00006148. IPD Sharing: Not stated. Countries: 1. Publications: 3.
System Biology of Spleen Deficiency Syndrome
ClinicalTrials.gov study NCT02915393. IPD Sharing: UNDECIDED. Countries: 0. Publications: 1.
Comparison of Kimura Versus Warshaw Technique for Laparoscopic Spleen-Preserving Distal Pancreatectomy
ClinicalTrials.gov study NCT06167421. IPD Sharing: Not stated. Countries: 0. Publications: 9.
Data from: Immune challenges decrease biliverdin concentration in the spleen of Northern Bobwhite Quail, Colinus virginianus
Open the record for dataset details and reuse information.
Data from: Ageratina adenophora causes spleen toxicity by inducing oxidative stress and pyroptosis in mice
Open the record for dataset details and reuse information.
Transcriptomic analysis of spleens from mice subjected to chronic low-dose radiation hindlimb unloading or a combination of both
The purpose of this study was to evaluate transcriptional changes in mouse spleens using a ground-based model for spaceflight. This model includes prolonged unloading and low-dose irradiation. Low-dose-rate gamma-radiation was delivered to 6-month old female C57BL/6J mice using 57Co plates (0.04 Gy) to simulate the radiation environment of spaceflight. Anti-orthostatic tail suspension was used to model the unloading fluid shift and physiological stress aspects of the microgravity component of spaceflight. Mice were hindlimb suspended and/or irradiated for 21 days. Mice were euthanized and spleens collected 7 days following treatment. RNA sequencing data was generated to assess transcriptional changes in these spleens.
Transcriptome analysis of murine spleen in space
Our study aims to comprehensively understand effects induced by the space environment on mammals. To achieve this aim we analyze the male mice housed under environments as the artificial gravity and the microgravity (space environment) in Japanese Experiment Module JEM) of the International Space Station (ISS) on orbit for 35 days. After recovered these mice on the ground transcriptome analysis by next-generation sequencing technology is performed about spleen to examine alteration of gene expression in the space.
Transcriptional analysis of spleens from mice preserved with the Rapid Freeze hardware
Data from the NASA Rodent Research-1 (RR-1) mission showed that gene-expression levels in mouse livers are different depending on what tissue preservation protocol is used and that slow freezing is not an effective method for preserving signals in gene-expression data. In response to these and other observations the Rapid Freeze hardware was built for use on the International Space Station. The Rapid Freeze hardware freezes mouse tissues (Glovebox freezer) and whole carcasses (Cryochiller) at rates closely mimicking those attained with immersion in liquid nitrogen. Because this hardware will be used extensively on future rodent research missions it is crucial to understand whether or not it preserves signals in gene expression data in order to maximize the value of these rare and expensive spaceflight experiments. Therefore this study was designed with three goals: 1) To evaluate the temperature profile of the Cryochiller and Glovebox freezer cartridges (Rapid Freeze hardware) over time during mock on-orbit procedures; 2) To determine the freezing profiles of tissues and carcasses using Rapid Freeze hardware at both optimal and sub-optimal temperatures (to mimic on-orbit operations) compared with those frozen in liquid nitrogen (the laboratory gold standard) or frozen in at -80 C (the current standard method); 3) To identify gene expression changes in a) tissues that were frozen via the Glovebox freezer and b) tissues dissected from whole or partial carcasses that were frozen via the Cryochiller versus tissues that were frozen via control methods (liquid nitrogen or -80C slow freeze) to assess how the Rapid Freeze hardware compares with laboratory gold standard practices and our current standard methods.
Single-cell RNA-seq uncovers unique gene expression profiles in the spleen of hypoxic mice
GEO Series GSE219259. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Loss of SIRPα promotes podocytes presenting antigen to activate specific T cell immune responses in lupus nephritis via activating spleen tyrosine kinase
GEO Series GSE240916. Mus musculus. 2 samples. Type: Expression profiling by array.
ChIP-seq from spleen (ENCSR028YEV)
GEO Series GSE105263. Homo sapiens. 1 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Murine Spleen: Wild type vs Brx haploinsufficiency
GEO Series GSE10117. Mus musculus. 6 samples. Type: Expression profiling by array.
ChIP-seq from spleen (ENCSR384HXX)
GEO Series GSE127617. Homo sapiens. 1 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Control ChIP-seq from spleen (ENCSR711URW)
GEO Series GSE143064. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Early and Delayed STAT1-Dependent Responses Drive Local Trained Immunity of Macrophages in the Spleen [bulk_RNA_seq_MS4A3]
GEO Series GSE252009. Mus musculus. 53 samples. Type: Expression profiling by high throughput sequencing.
Comparison of microRNA expression profiling in pig spleens among three time points after infection by Chinese I genotype strain of Toxoplasma gondii
GEO Series GSE113130. Sus scrofa. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Transcriptomic characterisation of phenotypic haematopoietic stem cells from human adult bone marrow, spleen and peripheral blood
GEO Series GSE143567. Homo sapiens. 836 samples. Type: Expression profiling by high throughput sequencing.
Effects of IL-1b inhibition on the phenotypes of spleen naive CD4+ T (TN) cells.
GEO Series GSE215777. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
A diverse fibroblastic stromal cell landscape in the spleen directs tissue homeostasis and immunity
GEO Series GSE185313. Mus musculus. 5 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.