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633
datasets available to search
ShareScore release 0.7.1
Dataset results
633 results for “TCR”
huARdb Database V2 JSON Files TCR Partition 1
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huARdb Database V2 JSON Files TCR Partition 4 [E-F]
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huARdb Database V2 JSON Files TCR Partition 7 [P]
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huARdb Database V2 JSON Files TCR Partition 5 [F-L]
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huARdb Database V2 JSON Files TCR Partition 9 [U]
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huARdb Database V2 JSON Files TCR Partition 5 [G]
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huARdb Database V2 JSON Files TCR Partition 10
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Screen of ESK1 TCR mimic antibody against a library of HLA-A*02:01 MHC-I peptides
<p>Minigene sequencing of T2 cells sorted for high and low binding to the TCR mimic antibody "ESK1."</p>
Longitudinal Assessment of TCR Repertoires in Recipients of Inactivated SARS-CoV-2 Vaccines: An Artificial Intelligence-Guided Study
<p>T cells play a crucial role in mitigating disease severity during SARS-CoV-2 infection and in shaping long-term immune memory. However, the precise molecular immune response involving T-cell receptor (TCR) repertoire changes following full vaccination, and evaluating vaccine efficacy through TCR analysis, remains incompletely understood. In this study, we conducted a 10-month longitudinal investigation of individuals who received SARS-CoV-2 inactivated vaccines and developed a vaccine efficacy evaluation model. Through the advanced large language artificial intelligence method, we identified vaccine-specific TCR clones, 3 V genes, 20 V-J combinations, and 3 epitopes, and traced their longitudinal development. The vaccine-specific TCR clones expanded to peak levels after the second vaccine dose and remained detectable in most subjects at 10 months. Utilizing vaccine-specific TCRs as novel markers, we constructed a vaccine efficacy evaluation model that predicts antibody levels with a mean AUC of 0.96, highlighting the relationship between vaccine-specific TCRs and antibodies. Our findings reveal the longitudinal patterns of vaccine-specific TCR clones and the potential of the efficacy evaluation model built upon them.</p>
Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer
ClinicalTrials.gov study NCT04146298. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer
ClinicalTrials.gov study NCT03240861. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study of TCR-Redirected T Cell Infusion in Subject With Recurrent HBV-related HCC Post Liver Transplantation
ClinicalTrials.gov study NCT02719782. IPD Sharing: NO. Countries: 1. Publications: 4.
CMV-TCR-T Cells for CM Virus Infection After HSCT
ClinicalTrials.gov study NCT04153279. IPD Sharing: Not stated. Countries: 1. Publications: 1.
68Ga-TCR-FAPI PET/CT in Patients With Various Types of Cancer
ClinicalTrials.gov study NCT06084767. IPD Sharing: NO. Countries: 1. Publications: 0.
E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers
ClinicalTrials.gov study NCT05639972. IPD Sharing: YES. Countries: 1. Publications: 1.
Safety and Efficacy of Anti-EBV Autologous TCR-T Cell Injection in Relapsed/Refractory EBV-Positive Lymphoma
ClinicalTrials.gov study NCT07162012. IPD Sharing: UNDECIDED. Countries: 1. Publications: 15.
Blinatumomab After TCR Alpha Beta/CD19 Depleted HCT
ClinicalTrials.gov study NCT04746209. IPD Sharing: Not stated. Countries: 1. Publications: 0.
TCR Modified T Cells MDG1011 in High Risk Myeloid and Lymphoid Neoplasms
ClinicalTrials.gov study NCT03503968. IPD Sharing: Not stated. Countries: 1. Publications: 1.
NY-ESO-1-specific T Cell Receptor (TCR) T Cell in Sarcoma
ClinicalTrials.gov study NCT03462316. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Trial of Plerixafor/G-CSF as Additional Agents for Conditioning Before TCR Alpha/Beta Depleted HSCT in WAS Patients
ClinicalTrials.gov study NCT03019809. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.