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opencc-by-4.0Jul 2022View details →

Figs 4, 5 in Effects of diet and feed composition on antibacterial activity of hemolymph of saproxylic beetles: A case study of Zophobas atratus (Coleoptera: Tenebrionidae)

Figs 4, 5. Results of photometric bacterial test. Dynamics of effects of artificial and

opencc-by-nc-nd-4.0Oct 2017View details →

Supporting Information for the article "Synthesis and Antibacterial Activity of Polymerizable Acryloyloxyalkyltriethyl Ammonium Salts", published in ChemPlusChem 2017, 82(10), 1235-1244.

Supporting Information for the article "Synthesis and Antibacterial Activity of Polymerizable Acryloyloxyalkyltriethyl Ammonium Salts", published in ChemPlusChem 2017, 82(10), 1235-1244 (DOI: 10.1002/cplu.201700194). The file is available free of charge at the publisher's website at the following URL: http://onlinelibrary.wiley.com/store/10.1002/cplu.201700194/asset/supinfo/cplu201700194-sup-0001-misc_information.pdf?v=1&s=3935a62996b49f0a39ddac08c0d37928db2dc817 The file contains the characterization data and the copy of 1H and 13C NMR Spectra for all product synthesized in the paper published in ChemPlusChem 2017, 82(10), 1235-1244 (DOI: 10.1002/cplu.201700194).

opencc-by-4.0Jul 2020View details →

Figure 6 in Synthesis of silver nanoparticles using Lactobacillus bulgaricus and assessment of their antibacterial potential

Figure 6. EDS Analysis of AgNPs synthesized by Lactobacillus bulgaricus.

opencc-by-4.0Jul 2020View details →

Figure 3 in Synthesis of silver nanoparticles using Lactobacillus bulgaricus and assessment of their antibacterial potential

Figure 3. Results of suspension at different AgNO 3 concentrations of Lactobacillus bulgaricus.

Figure 1 in Metal nanoparticles produced by plants with antibacterial properties against Staphylococcus aureus

Figure 1. Synthesis of metal nanoparticles using plant extracts.

opencc-by-4.0Feb 2024View details →

Data for a publication "Polymer-metal bilayer with alkoxy groups for antibacterial improvement"

Abstract: Many bio‐applicable materials, medical devices, and prosthetics combine both polymer and metal components to benefit from their complementary properties. This goal is normally achieved by their mechanical bonding or casting only. Here, we report an alternative easy method for the chemical grafting of a polymer on the surfaces of a metal or metal alloys using alkoxy amine salt as a coupling agent. The surface morphology of the created composites was studied by various microscopy methods, and their surface area and porosity were determined by adsorption/desorption nitrogen isotherms. The surface chemical composition was also examined by various spectroscopy techniques and electrokinetic analysis. The distribution of elements on the surface was determined, and the successful bonding of the metal/alloys on one side with the polymer on the other by alkoxy amine was confirmed. The composites show significantly increased hydrophilicity, reliable chemical stability of the bonding, even interaction with solvent for thirty cycles, and up to 95% less bacterial adhesion for the modified samples in  comparison with pristine samples, i.e., characteristics that are promising for their application in the biomedical field, such as for implants, prosthetics, etc. All this uses universal, two-step procedures with minimal use of energy and the possibility of production on a mass scale.

Table 3 in Phytochemical characterization, and antioxidant and antibacterial activities of the hydroethanolic extract of Anadenanthera peregrina stem bark

Table 3. Diameter of the inhibitory zone of the hydroethanolic extract of Anadenanthera peregrina stem bark against Staphylococcus aureus (ATCC 25923) and Escherichia coli (ATCC 25922).<table><tbody><tr><th></th><th>A. peregrina extract concentration</th><th></th><th></th></tr></tbody><tbody><tr><th>Strain</th><td></td><td></td><td></td><td>C +</td><td>C -</td></tr><tr><th></th><td>50 µL</td><td>100 µL</td><td>200 µL</td><td></td><td></td></tr><tr><th>E. coli</th><td>-</td><td>-</td><td>-</td><td>29 mm</td><td>-</td></tr><tr><th>S. aureus</th><td>10 mm</td><td>16 mm</td><td>20 mm</td><td>35 mm</td><td>-</td></tr></tbody></table>

Table 2 in Phytochemical characterization, and antioxidant and antibacterial activities of the hydroethanolic extract of Anadenanthera peregrina stem bark

Table 2. Physicochemical properties,antioxidant activity,and total phenolic content of the hydroethanolic extract of A.peregrina stem bark.<table><tbody><tr><th>Sample</th><th>pH</th><th>Density (g cm 3)</th><th>DPPH (IC 50)</th><th>Total Phenolics (g GAE 100 g- 1)</th></tr></tbody><tbody><tr><th>A. peregrina extract</th><td>5.21 ± 0.01</td><td>0.956</td><td>44.13 mg mL-1</td><td>6.40 ± 0.08</td></tr></tbody></table>

Table 1 in Phytochemical characterization, and antioxidant and antibacterial activities of the hydroethanolic extract of Anadenanthera peregrina stem bark

Table 1. Phytochemical prospecting of the main secondary metabolite groups of the hydroethanolic extract of A. peregrina stem bark.<table><tbody><tr><th>Secondary metabolite</th><th>Hydroethanolic extract of A. peregrina</th></tr><tr><th>Cardiac glycosides</th></tr></tbody><tbody><tr><th>Kedd reagent test</th><td>++</td></tr><tr><th>Keller–Kiliani reagent test</th><td>++</td></tr><tr><th>Baljet reagent test</th><td>-</td></tr><tr><th>Raymond–Marthoud reagent test</th><td>+++</td></tr><tr><th>Alkaloids</th></tr><tr><th>Libermann–Bouchardat reagent test</th><td>-</td></tr><tr><th>Wagner reagent test</th><td>-</td></tr><tr><th>Mayer’s reagent test</th><td>-</td></tr><tr><th>Organic acids</th></tr><tr><th>Pascová reagent test</th><td>++</td></tr><tr><th>Reducing sugars</th></tr><tr><th>Fehling reagent test</th><td>++</td></tr><tr><th>Non-reducing sugars</th></tr><tr><th>Fehling + HCl test</th><td>-</td></tr><tr><th>Coumarins</th></tr><tr><th>UV light 254 and 365 nm</th><td>+</td></tr><tr><th>Saponins</th></tr><tr><th>Foamy</th><td>-</td></tr><tr><th>Haemolytic</th><td>+++</td></tr><tr><th>Polysaccharides</th></tr><tr><th>Reactive lugol</th><td>-</td></tr><tr><th>Phenols</th></tr><tr><th>FeCl 3 Tannins</th><td>+++</td></tr><tr><th>FeCl3 Flavonoids</th><td>Gr</td></tr><tr><th>Pb(C2 H 3O2)2</th><td>++</td></tr><tr><th>Purines</th><td>-</td></tr><tr><th>Catechins</th><td>+++</td></tr><tr><th>Benzoquinone derivatives</th><td>+++</td></tr><tr><th>Depsids and depsidones</th><td>+++</td></tr><tr><th>Steroids and triterpenoids</th><td>-</td></tr><tr><th>Sesquiterpenolactones</th><td>-</td></tr></tbody></table>

opencc-by-4.0Jun 2020View details →

Different sources of natural products from the (a) bacterial, (b) archaeal, (c) fungal, (d) protozoan, (e) chromistan, (f) plant and (g) animal kingdoms, the rationale(s) for screening them for antibacterial activity, and associated advantages and disadvantages

This table of information is from the review article 'Bioprospecting for Antibacterial drugs: A Multidisciplinary Perspective on Natural Product Source Material, Bioassay Selection and Avoidable Pitfalls' (<a href="https://doi.org/10.1007/s11095-020-02849-1">https://doi.org/10.1007/s11095-020-02849-1</a>).

opencc-zeroApr 2023View details →

Drosophila survival after infection and Buletin antibacterial activity data

Antimicrobial peptides (AMPs) are key players in innate defence against infection in plants and animals. In Drosophila, many host defence peptides are produced downstream of the Toll and Imd NF-κB pathways. Use of single and compound AMP mutations in Drosophila has revealed that AMPs can additively or synergistically contribute to combat pathogens in vivo. However, these studies also revealed a high degree of specificity, wherein just one AMP can play a major role in combatting a specific pathogen. We recently uncovered a specific importance of the antibacterial peptide Drosocin for defence against Enterobacter cloacae. Here, we show that the Drosocin locus (CG10816) is more complex than previously described. In addition to its namesake peptide "Drosocin", it encodes a second peptide generated from a precursor via furin cleavage. We name this peptide "Buletin", and show that it corresponds to the uncharacterized "Immune-induced Molecule 7" previously identified by MALDI-TOF. The existence of a naturally occurring polymorphism (Thr52Ala) in the CG10816 precursor protein masked the identification of this peptide previously. Using mutations differently affecting the production of these two CG10816 gene products, we show that Drosocin, but not Buletin, contributes to the CG10816-mediated defence against E. cloacae. Strikingly, we observed that Buletin, but not Drosocin, contributes to the CG10816-mediated defence against Providencia burhodogranariea. Moreover, the Thr52Ala polymorphism in Buletin affects survival to P. burhodogranariea, wherein the Alanine allele confers better defence than the Threonine allele. However, we found no activity of Buletin against either P. burhodogranariea or E. coli in vitro. Collectively, our study reveals that CG10816 encodes not one but two prominent host defence peptides with different specificity against different pathogens. This finding emphasizes the complexity of the Drosophila humoral response consisting of multiple host defence peptides with specific activities, and demonstrates how natural polymorphisms found in Drosophila populations can affect host susceptibility.

opencc-zeroSep 2023View details →

Bacterial mediated green synthesis of silver nanoparticles and their antibacterial and antifungal activities against drug-resistant pathogens

In the healthcare sector, the production of bioactive silver nanoparticles (AgNPs) with antimicrobial properties is of great importance. In this study, a novel bacterial strain, Paenibacillus sp. MAHUQ-63, was identified as a potential candidate for facile and rapid biosynthesis of AgNPs. The synthesized AgNPs were used to control the growth of human pathogens, Salmonella Enteritidis and Candida albicans. The bacterial culture supernatant was utilized to synthesize the nanoparticles. FE-TEM examination showed spherical-shaped nanoparticles with 15 to 55 nm in size. FTIR analysis identified various functional groups. The synthesized AgNPs demonstrated remarkable activity against S. Enteritidis and C. albicans. The zone of inhibition (ZOI) for 100 µL (0.5 mg/mL) of AgNPs against S. Enteritidis and Candida albicans were 18.0 ± 1.0 and 19.5 ± 1.3 mm, respectively. The minimum inhibitory concentrations (MICs) were 25.0 and 12.5 μg/mL against S. Enteritidis and Candida albicans, respectively. Additionally, the minimum bactericidal concentrations (MBC) were 25.0 μg/mL against both pathogenic microbes. The FE-SEM analysis showed that the treatment of AgNPs caused morphological and structural damage to both S. Enteritidis and Candida albicans. Therefore, these AgNPs can be used as a new and effective antimicrobial agent.

closedIPD-NOFeb 2026View details →

Nobio Clinical Study - Demineralization Prevention With a New Antibacterial Restorative Composite

ClinicalTrials.gov study NCT04059250. IPD Sharing: NO. Countries: 1. Publications: 15.

restrictedIPD-UNDECIDEDFeb 2026View details →

Efficacy of an Antibacterial Toothpaste and Patients' Satisfaction

ClinicalTrials.gov study NCT05569850. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.

controlledIPD-YESFeb 2026View details →

Antibacterial Effect of Nano Silver Fluoride vs Chlorhexidine on Occlusal Carious Molars Treated With Partial Caries Removal Technique

ClinicalTrials.gov study NCT03186261. IPD Sharing: YES. Countries: 1. Publications: 1.

restrictedIPD-UNDECIDEDFeb 2026View details →

Safety, Efficacy and Pharmacokinetics of CF-301 vs. Placebo in Addition to Antibacterial Therapy for Treatment of S. Aureus Bacteremia

ClinicalTrials.gov study NCT03163446. IPD Sharing: Not stated. Countries: 14. Publications: 1.

controlledIPD-YESFeb 2026View details →

Antibacterial Efficacy and Outcomes of Root Canal Irrigation Methods

ClinicalTrials.gov study NCT06959602. IPD Sharing: YES. Countries: 1. Publications: 27.

publicAug 2025View details →

Data from: Microwave-assisted graphene oxide/carbon spheres with silver nanoparticles: Dual catalyst for peroxide detection and antibacterial use

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publicNov 2023View details →

Data for: Fabrication and characterization of antibacterial coatings using an amphoteric condensed tannin,Tanfloc

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