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523 results for “cell migration”
A multiscale theory for spreading and migration of adhesion-reinforced mesenchymal cells
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Effect of heterogeneous substrate adhesivity of follower cells on speed and tension profile of leader cells in primary keratocyte collective cell migration
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Dermomyotome-derived endothelial cells migrate to the dorsal aorta to support hematopoietic stem cell emergence
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Data_Figure 3_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of figure 3 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. 3). Corresponding raw data obtained from a) cellomics HTC array scan analysis provided as three files in CSV format (31003A-179400_Date_examiner_17BHSD12_8_2_1-3). Migration potential as three files in CSV format (31003A-179400_ date_examiner_17BHSD12_16_2_1-3); b) mRNA content analyzed by RT-PCR provided as six files in CSV format (31003A-179400_date_examiner_17BHSD12_1_3_1-6); c) western blot and densitometry provided as eight files in CSV format 31003A-179400_date_examiner_2_1-2_1-8). All further experiment related information protocols and subsequent data analysis provided as meta-data-files (31003A-179400_date_examiner_17BHSD12_8/16/1_dataset_M_1) as TXT format and (31003A-179400_date_examiner_17BHSD12_2_dataset_M_2-3) as PNG format.</p>
Data_supplemental figure 7_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 7 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S7). Corresponding raw data obtained from xCELLigence provided as six files in CSV format (31003A-179400_date_examiner_17BHSD12_9_3-4_1-3). All further experiment related information and subsequent data analysis provided as a) two meta-data-file 31003A-179400_ date_examiner_17BHSD12_9_3-4_M_1) as TXT format.</p>
Data_supplemental figure 3_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 3 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S3). Corresponding raw data from a) western blot and densitometry provided as 11 files in CSV format (31003A-179400_date_examiner_17BHSD12_2_18-20_1-3) b) cellomics HTC array scan analysis provided as four files in CSV format (31003A-179400_Date_examiner_17BHSD12_8_13_1-4). All further experiment related information protocols and subsequent data analysis provided as meta-data-files (31003A-179400_date_examiner_17BHSD12_2/8_dataset_M_1) as TXT format and (31003A-179400_date_examiner_17BHSD12_2_dataset_M_2-3) as PNG format.</p>
Data_supplemental figure 6_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 6 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S6). Corresponding raw data from a-c) cellomics HTC array scan analysis provided as 19 files in CSV format (31003A-179400_Date_examiner_17BHSD12_8_14-17_1-5), d) western blot and densitometry provided as five files in CSV format (31003A-179400_date_examiner_17BHSD12_2_21_1-5). All further experiment related information protocols and subsequent data analysis provided as meta-data-files (31003A-179400_date_examiner_17BHSD12_2/8_dataset_M_1) as TXT format and (31003A-179400_date_examiner_17BHSD12_2_dataset_M_2-3) as PNG format.</p>
Data_Figure 1_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of figure 1 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1007_s00018-019-03227-w_CMLS_Fig1). Corresponding raw data obtained from a) cellomics HTC array scan analysis provided as seven files in CSV format (31003A-179400_Date_examiner_17BHSD12_8_1_1-7), b) raw data obtained from proliferation investigation on xCELLigence provided as one (31003A-179400_date_examiner_17BHSD12_9_1_1) file in CSV format. All further experiment related information and subsequent data analysis provided as two meta-data-files as TXT format (31003A-179400_date_examiner_17BHSD12_8/9_1_M_1).</p>
Data_supplemental figure 10_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 10 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S10). Corresponding raw data obtained from a/b) western blot and densitometry provided as 20 files in CSV format (31003A-179400_date_examiner_17BHSD12_2_27-30_1-5), c) mRNA content analyzed by RT-PCR provided as 10 files in CSV format (31003A-179400_date_examiner_17BHSD12_1_11-12_1-6). d) RT-PCR provided as 10 files in CSV format (31003A-179400_date_examiner_17BHSD12_1_13_1-4). All further experiment related information protocols and subsequent data analysis provided as meta-data-files (31003A-179400_date_examiner_17BHSD12_1/2_dataset_M_1) as TXT format and (31003A-179400_date_examiner_17BHSD12_2_dataset_M_2-3) as PNG format.</p>
Data_supplemental figure 9_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 9 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S9). Corresponding raw data obtained from a) western blot and densitometry provided as four files in CSV format (31003A-179400_date_examiner_17BHSD12_2_23_1-5); b) Cellomics HTC array scan analysis provided as eight files in CSV format (31003A-179400_Date_examiner_17BHSD12_8_19-20_1-5); c) western blot and densitometry provided as four files in CSV format (31003A-179400_date_examiner_17BHSD12_2_26_1-3), d) mRNA content analyzed by RT-PCR provided as 10 files in CSV format (31003A-179400_date_examiner_17BHSD12_1_9-10_1-6), e) western blot and densitometry provided as four files in CSV format (31003A-179400_date_examiner_17BHSD12_2_25_1-3), f) western blot and densitometry provided as four files in CSV format (31003A-179400_date_examiner_17BHSD12_2_24_1-3) All further experiment related information protocols and subsequent data analysis provided as meta-data-files (31003A-179400_date_examiner_17BHSD12_1/2/8_dataset_M_1) as TXT format and (31003A-179400_date_examiner_17BHSD12_2_dataset_M_2-3) as PNG format.</p>
Data_supplemental figure 8_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 8 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S8). Corresponding raw data obtained from a) cellomics HTC array scan analysis provided as five files in CSV format (31003A-179400_Date_examiner_17BHSD12_8_18_1-5); b) western blot and densitometry provided as four files in CSV format (31003A-179400_date_examiner_17BHSD12_2_22_1-4), investigation of migration on xCELLigence provided as four (31003A-179400_date_examiner_17BHSD12_9_5_1) files in CSV format. All further experiment related information protocols and subsequent data analysis provided as meta-data-files (31003A-179400_date_examiner_17BHSD12_2/8/9_dataset_M_1) as TXT format and (31003A-179400_date_examiner_17BHSD12_2_dataset_M_2-3) as PNG format.</p>
Data_supplemental figure 5_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 5 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S5). Corresponding raw data from immunofluorescence measurements provided as three files (31003A-179400_20190528_MT, PST, ADU_17BHSD12_13_2_1-3) in png format. All further experiment related information protocols and subsequent data analysis provided as meta-data-file (31003A-179400_date_examiner_17BHSD12_13_2_M_1) as TXT format.</p>
Data_supplemental figure 1_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 1 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S1). (31003A-179400_date_examiner_17BHSD12_2_14-17) PNG format. All further experiment related information protocols as meta-data-files (31003A-179400_date_examiner_17BHSD12_2_dataset_M_1) as TXT format.</p>
Data_Figure 8_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of figure 8 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. 8). Corresponding raw data obtained from a1/2) Western blot and densitometry provided as three files in CSV format (31003A-179400_date_examiner_17BHSD12_2_9_1-3), mRNA content analyzed by RT-PCR provided as four files in CSV format (31003A-179400_date_examiner_17BHSD12_1_7_1-4); b) Western blot and densitometry provided as three files in CSV format (31003A-179400_date_examiner_17BHSD12_2_10-11_1-3); c1/2) mRNA content analyzed by RT-PCR provided as four files in CSV format (31003A-179400_date_examiner_17BHSD12_1_8_1-4), d1/2) Western blot and densitometry provided as seven files in CSV format (31003A-179400_date_examiner_17BHSD12_2_12-13_1-4). All further experiment related information protocols and subsequent data analysis provided as meta-data-files (31003A-179400_date_examiner_17BHSD12_2/1_dataset_M_1) as TXT format and (31003A-179400_date_examiner_17BHSD12_2_dataset_M_2-3) as PNG format.</p>
Data_supplemental figure 4_Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration
<p>Data of supplemental figure 4 from Impact of 17β‑HSD12, the 3‑ketoacyl‑CoA reductase of long‑chain fatty acid synthesis, on breast cancer cell proliferation and migration</p> <p>Dataset (doi: 10.1007/s00018-019-03227-w) contains the original figure as TIF-format (10.1194_jlr.M092908_Fig. S4). Corresponding raw data from immunofluorescence measurements provided as three files (31003A-179400_date_examiner_17BHSD12_13_1_1-3) in png format. All further experiment related information protocols and subsequent data analysis provided as meta-data-file (31003A-179400_date_examiner_17BHSD12_13_1_M_1) as TXT format.</p>
Data from: Ovarian BDNF promotes survival, migration, and attachment of tumor precursors originated from p53 mutant fallopian tube epithelial cells
<p class="CxSpFirst"><span>High-grade serous ovarian carcinoma (HGSOC) is the most lethal gynecological malignancy. New evidence supports a hypothesis that HGSOC can originate from fallopian tube epithelium (FTE). It is unclear how genetic alterations and pathophysiological processes drive the progression of FTE tumor precursors into widespread HGSOCs. In this study, we uncovered that brain-derived neurotrophic factor (BDNF) in the follicular fluid stimulates the tropomyosin receptor kinase B (TrkB)-expressing FTE cells to promote their survival, migration, and attachment. Using <i>in vitro</i> and <i>in vivo</i> models, we further identified that the acquisition of common TP53 gain-of-function (GOF) mutations in FTE cells led to enhanced BDNF/TrkB signaling comparing to that of FTE cells with <i>TP53</i> loss-of-function (LOF) mutations. Different mutant p53 proteins can either increase TrkB transcription or enhance TrkB endocytic recycling. Our findings have demonstrated possible interplays between genetic alterations in FTE tumor precursors (i.e., p53 gain-of-function mutations) and pathophysiological processes (i.e., the release of follicular fluid upon ovulation) during the initiation of HGSOC from the fallopian tube. Our data revealed molecular events underlying the link between HGSOC tumorigenesis and ovulation, a physiological process that has been associated with risk factors of HGSOC. </span></p>
Long-term time-lapse live imaging reveals extensive cell migration during annelid regeneration
<p>Supporting Materials for the article:<br /> Long-term time-lapse live imaging reveals extensive cell migration during annelid regeneration</p> <p>Eduardo E. Zattara, Kate W. Turlington and Alexandra E. Bely</p> <p>BMC Developmental Biology, 2016</p> <p>Includes 11 movies and one compressed file with R code and data tables.</p>
ComplexEye - a multi lens array microscope for High-Throughput embedded immune cell migration analysis
<p>This dataset contains raw high-resolution movies of migrating neutrophils, which were recorded using the ComplexEye, an array microscope with 16 independent aberration-corrected glass lenses spaced at the pitch of a 96-well plate. Please see the manuscript "ComplexEye - a multi lens array microscope for High-Throughput embedded immune cell migration analysis" for more information.</p><p>The movies can be assigned to the following figures in the manuscript:</p><ul><li>96-well_plate_movies_n=1_complexeye.zip: Figure 3a</li><li>96-well_plate_movies_n=1_leica.zip: Figure 3a</li><li>384-well_plate_movies_n=1_complexeye.zip: Figure 3b</li><li>384-well_plate_movies_n=16_complexeye.zip: Figure 3c</li><li>R01.zip - R17.zip: Figure 4 and 5</li></ul>
Supplementary videos: CD56/NCAM mediates cell migration of human NK cells by promoting integrin-mediated adhesion turnover [preprint]
Open the record for dataset details and reuse information.
Supplementary PyMOL sessions for "Small protein blockers of human IL-6 receptor alpha inhibit proliferation and migration of cancer cells"
<p>PyMOL sessions with summary of NEF variants docking to IL-6R. Supplementary to "Small protein blockers of human IL-6 receptor alpha inhibit proliferation and migration of cancer cells".</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.