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Dataset results
752 results for “combined use”
Novel Insights into the Bioactive Metabolites of Macrocybe gigantea (Massee) Pegler & Lodge, a Wild Edible Macrofungi Using Gas Chromatography Mass Spectrometry (GC-MS) Combined with Chemoinformatics Approaches
<p><em>Macrocybe gigantea </em>(MG) is an edible mushroom and has multiple pharmacological activities such as antibacterial, antioxidant, and antitumor activities. However, only a few reports were available on the bioactive compounds and bioactivity of this mushroom. In this concern, the present study was aimed to explore the unique chemical diversity from the fruiting body of MG<em>. </em>The species identification was done accurately with morphological and molecular methods followed by mycochemical extraction in different solvent systems. The ethanolic extract of the fruiting body gave maximum yield and its Gas Chromatography-Mass Spectrometry (GC-MS) analysis was performed along with antibacterial activity and cell viability by MTT assay. The GC-MS analysis revealed 50 metabolites and further chemoinformatics analysis of these metabolites revealed their possible biological activities. In addition, the mushrooms' physico-chemical and mineral element analysis revealed the quality and authenticity of the species. Altogether, the current investigation gives a comprehensive overview of the bioactive metabolites of MG.</p>
Combined palaeohistological and isotopic inferences of thermometabolism in extinct Neosuchia, using Goniopholis and Dyrosaurus (Pseudosuchia: Crocodylomorpha) as case studies
<p>The evolution of thermometabolism in pseudosuchians (Late Triassic to the present) remains a partly unsolved issue: extant taxa (crocodilians) are ectothermic, but the clade was inferred ancestrally endothermic. Here we inferred the thermometabolic regime of two neosuchian groups, Goniopholididae (Early Jurassic to Late Cretaceous) and Dyrosauridae (Middle Cretaceous to Late Eocene), close relatives of extant crocodilians, in order to elucidate the evolutionary pattern across Metasuchia (Early Jurassic to the present), a clade comprising Neosuchia (Early Jurassic to the present) and Notosuchia (Middle Jurassic until Late Miocene). We propose a new integrative approach combining geochemical analyses to infer body temperature from the stable oxygen isotope composition of tooth phosphate and palaeohistology and phylogenetic comparative methods to infer resting metabolic rates (RMR) and red blood cells dimensions. †Dyrosaurus and †Goniopholis share with extant crocodilians similar lifestyles, body forms, bone tissue organization, body temperatures (Tb), metabolic rates and red blood cells dimensions. Consistently, we infer ectothermy for †Dyrosaurus and †Goniopholis with the parsimonious implication of neosuchians and metasuchians as being primitively ectothermic.</p>
CoCon: A Data Set on Combined Contextualized Research Artifact Use
<p>CoCon is a large graph data set reflecting the combined use of research artifacts, contextualized in academic publications’ full-text. It comprises 35 k artifacts (data sets, methods, models, and tasks) and 340 k publications.</p> <p>The data set is generated from <a href="https://github.com/paperswithcode/paperswithcode-data">Papers With Code</a> and <a href="https://github.com/IllDepence/unarXive">unarXive</a>.</p> <p>You can find a Python package for loading the data as a NetworkX or Pytorch Geometric graph <a href="https://github.com/IllDepence/contextgraph">in this GitHub repository</a><br> </p>
Land cover maps: End-to-end Learning for Land Cover Classification using Irregular and Unaligned SITS by Combining Attention-Based Interpolation with Sparse Variational Gaussian Processes
<p>Land cover maps obtained with mTAN-GP, mTAN-MLP, mTAN-LTAE and raw-LTAE models for the year 2018 with Sentinel-2 acquisitions.</p> <p>For further details see the pre-print article "End-to-end Learning for Land Cover Classification using Irregular and Unaligned SITS by Combining Attention-Based Interpolation with Sparse Variational Gaussian Processes ". This article is available : <a href="https://hal.science/hal-04112115">here</a>.</p>
Data from: The combined effects of treated sewage discharge and land use on rivers
<p>Freshwater ecosystems are increasingly threatened by multiple anthropogenic stressors. Release of treated sewage effluent and pollution from agricultural or urban sources can independently reduce water quality with implications for ecological communities. However, our knowledge of the combined effects of these stressors is limited. We performed a field study to quantify the combined effect of treated sewage discharge and land use on nutrient concentrations, sewage fungus presence, and communities of macroinvertebrates and benthic algae. Over three seasons in four rivers we found that a model which included an interaction between sewage pollution and time of the year (i.e., months) was the best predictor of nutrient concentrations and the abundance of algae and sewage fungus. Both macroinvertebrate and algae communities shifted downstream of sewage input. Specifically, more tolerant groups, such as cyanobacteria and Oligochaetes, were more abundant. The EPT (Ephemeroptera, Plecoptera, and Tricoptera) water quality score was best explained by an interaction between month and agriculture in the surrounding landscape. Overall, our results show that sewage discharge has a significant impact on water quality and benthic riverine communities, regardless of the surrounding land uses. Agricultural inputs, however, could be more important than treated sewage discharge in reducing the abundance of sensitive invertebrate taxa. We need both improvements to wastewater treatment processes and reductions in agricultural pollution to reduce threats to vulnerable freshwater communities.</p>
A Clinical Study Assessing Critical Errors, Training/Teaching Time, and Preference Attributes of the ELLIPTA® Dry Powder Inhaler, in Comparison to Combinations of Dry Powder Inhalers Used to Provide T
ClinicalTrials.gov study NCT02982187. IPD Sharing: NO. Countries: 2. Publications: 1.
Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination Administered in Patients Infected With Chronic Genotype 1 or 4 HCV for Use in the Peri-Operative Liver Transplantation Setting
ClinicalTrials.gov study NCT02350569. IPD Sharing: YES. Countries: 1. Publications: 1.
Decreasing Severity of Acne Vulgaris After the Use of a Combination of Anti-Acne Cream
ClinicalTrials.gov study NCT04118296. IPD Sharing: NO. Countries: 1. Publications: 3.
Combined Bio- and Neuro- Feedback vs. Varenicline Use for Smoking Cessation
ClinicalTrials.gov study NCT02991781. IPD Sharing: YES. Countries: 3. Publications: 2.
A Clinical Study to Evaluate the Tolerability of a Topical Antibiotic and Retinoid Used in a Combined Regimen With a BPO Wash
ClinicalTrials.gov study NCT00891982. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Phase I/II Trial for Intravitreous Treatment of Severe Ocular Von Hippel-Lindau Disease Using a Combination of the PDGF Antagonist E10030 and the VEGF Antagonist Ranibizumab
ClinicalTrials.gov study NCT02859441. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study to Assess Adverse Events When Ubrogepant Tablets in Combination With Atogepant Tablets Are Used to Treat Adult Participants With Migraine
ClinicalTrials.gov study NCT05264129. IPD Sharing: YES. Countries: 1. Publications: 0.
The Efficacy and Safety of Atacicept in Combination With Mycophenolate Mofetil Used to Treat Lupus Nephritis
ClinicalTrials.gov study NCT00573157. IPD Sharing: Not stated. Countries: 5. Publications: 1.
Atazanavir Used in Combination With Other Anti-HIV Drugs in HIV-Infected Infants, Children, and Adolescents
ClinicalTrials.gov study NCT00006604. IPD Sharing: Not stated. Countries: 3. Publications: 2.
Gene Transfer for Severe Combined Immunodeficiency, X-linked (SCID-X1) Using a Self-inactivating (SIN) Gammaretroviral Vector
ClinicalTrials.gov study NCT01129544. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Histological Evaluation of Healing Following Ridge Preservation Using a Combined Cortical/Cancellous Mineralized Freeze-Dried Bone Allograft
ClinicalTrials.gov study NCT02275767. IPD Sharing: NO. Countries: 1. Publications: 1.
Clinical Study Using Biologics to Improve Multi OIT Outcomes (COMBINE)
ClinicalTrials.gov study NCT03679676. IPD Sharing: NO. Countries: 1. Publications: 1.
Does Concomitant Use of Combined Oral Hormonal Steroids Stop Bleeding in Women Using Etonogestrel Implants (Implanon/Nexplanon®)?: A Randomized Controlled Study
ClinicalTrials.gov study NCT01968135. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A5288/MULTI-OCTAVE: Management Using Latest Technologies to Optimize Combination Therapy After Viral Failure
ClinicalTrials.gov study NCT01641367. IPD Sharing: Not stated. Countries: 10. Publications: 4.
The Efficacy and Safety of Sildenafil Citrate Used in Combination With Intravenous Epoprostenol in PAH
ClinicalTrials.gov study NCT00159861. IPD Sharing: Not stated. Countries: 11. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.