Find research datasets worth reusing

opencc-zeroMay 2024View details →

Data from: Can faster growth compensate for increased mortality in subtropical dry forest fragments?

Capturing the effects of fragmentation and ongoing changing climate on the population dynamics of long-lived trees requires long-term datasets, but these are uncommon in rainforests and dry forests outside of the tropics. This study capitalised on nine 0.04-ha permanent plots established in 1982 within corridors of old-growth subtropical dry forest (Araucarian vine forest) retained as fire breaks within forestry plantations in Imbil (southern Queensland, Australia). Tree diameter growth and survival were censused in 1997 and 2021, resulting in two monitoring periods. The most recent period was associated with an increasing trend in vapour-pressure deficit (VPD). Consistent with this trend, we found that survival was substantially lower across all size classes in the second period. Mortality-induced reductions in stem density were associated with faster growth rates in all but the largest stems in the second period. Growth was also moderately faster in plots near forest edges in the second period. The richness of obligate understory species declined significantly by an average of 1.44 species over the 40-year study period. Synthesis and applications: Overall, our results are consistent with increasing tree mortality rates reported recently for the Australian wet tropics and suggest widespread and alarming impacts of increasing VPD on rainforest and dry forest community dynamics. To increase forest resilience in a changing climate, we recommend the retention of a buffer of plantation trees adjacent to old growth forest corridors; widening the forest corridors using faster-growing species identified in this study and maintaining connections between scrub breaks and larger tracts of forest for species dispersal.

opencc-by-4.0Oct 2017View details →

Links between Gestures and Multisensory Processing: Individual Differences Suggest a Compensation Mechanism

Dataset associated with the following publication: Schmalenbach, S.B., Billino, J., Kircher, T., van Kemenade, B.M.*, Straube, B*. (2017). Links between Gestures and Multisensory Processing: Individual Differences Suggest a Compensation Mechanism. Frontiers in Psychology 8:1828.

opencc-by-4.0Apr 2019View details →

Data from: Heritability of growth and leaf loss compensation in a long-lived tropical understorey palm

Data from: Heritability of growth and leaf loss compensation in a long-lived tropical understorey palm, PLOS ONE. Quantitative genetic data related to growth parameters and leaf loss compensation of 1402 Chamaedorea elegans seedlings. Data was collected in a greenhouse experiment performed at the Unifarm experimental facilities of Wageningen University between January 2013 and July 2014, in which a defoliation treatment was applied. Seeds were collected in the Montes Azules Biosphere Reserve in Chiapas, Mexico. See PLOS ONE publication for more details. The file contains a separate "read me" tab in which the meaning of the variable codes is explained.

opencc-by-4.0Jul 2021View details →

Fault test cases for series compensated transmission line with capacitor at line terminal

This data set contains time series data of different simulated fault cases in high voltage series compensated transmission lines. The simulation is done in PSCAD using the Python automation library. The capacitor is located at one of the line terminals with CT and VT. The modelled line is 500 kV and 200 km long. The simulation is run for 1 second with 10 kHz sampling rate.  Each file contains 7 data in the following order,  <ol> <li>Time</li> <li>Voltage phase A</li> <li>Voltage phase B</li> <li>Voltage phase C</li> <li>Current phase A</li> <li>Current phase B</li> <li>Current phase C</li> </ol> The variables used to study different test cases are shown below, <ul> <li>Fault inception angle (phase A): 0 and 90 degree</li> <li>Source impedance ratio: 0.20 and 0.35</li> <li>Capacitor level: 94 µF(50%), 78 µF(60%), 67 µF(70%)</li> <li>Fault resistance: 0.10, 10, 20, 30 ohm</li> <li>Fault location: 10 km reverse, 10 km, 50 km, 100 km, 125 km, 150 km, 155 km, 160 km. 165 km, 170 km, 180 km, 190 km</li> <li>Fault type: No-fault, AG, BG, CG, ABG, CAG, BCG, ABCG, AB, CA, BC, ABC</li> </ul> All these factors lead to 6912 test cases in total. The test cases are organized in four (4) zipped folders each containing 1728 test cases. The PSCAD model file and an example python script that can be used to automate the simulations are also included herewith for anyone interested to replicate the results.  The name of the folder contains the information regarding fault inception angle and source impedance ratio for all test cases inside that folder, for example, the folder name Outputs_0_0.20 can be decoded as, 0: Fault inception angle (phase A) 0.20: Source impedance ration The files names inside the folders include information about the other variables used in generating the test case. For example, the name test_f_10_0_67_0.01 can be interpreted as, test_f: f for forward fault, r for reverse fault 10: fault location, 10 km 0: Fault type 67: Compensation level 0.01: Fault resistance Fault types are interpreted as in PSCAD. 0 = No-Fault, 1 = Phase A to Ground 2 = Phase B to Ground 3 = Phase C to Ground 4 = Phase AB to Ground 5 = Phase AC to Ground 6 = Phase BC to Ground 7 = Phase ABC to Ground 8 = Phase AB 9 = Phase AC 10 = Phase BC 11 = Phase ABC The different line parameters used in the PSCAD model is as below, Conductor Type: Chukar Geometric mean radius: 20.345 mm DC resistance: 0.0318Ω/km Strands: 84 Strand radius: 1.8491 mm Relative permeability: 1.0 Sag: 12 m Height: 22 m Sub-conductor: 2 Sub-conductor spacing: 0.4572 m Ground wire number: 2 Radius: 5.5245 mm DC resistance: 2.8645Ω/km Relative permeability: 1.0 Sag: 10 m Height: 10 m Impedance Positive sequence0.018 +j0.339 Ω/km Zero sequence0.266 +j1.017 Ω/km   These simulations were run for assessing time-domain protections. Therefore, the parallel CB protection across the series capacitor is disabled, as one can safely assume even with the highest current levels, the CB will take at least 20 ms to operate. This is higher than the time limits for time-domain protection.

opencc-zeroAug 2021View details →

Epigenetic mechanisms of partial dosage compensation in an avian, female heterogametic system

The evolution of genetic sex determination is often accompanied by degradation of one of the proto sex chromosomes. Male heterogametic systems have evolved convergent, epigenetic mechanisms restoring the resulting imbalance in gene dosage between diploid autosomes (AA) and the hemizygous sex chromosome (X). Female heterogametic systems (AAf ZWf, AAm ZZm) tend to only show partial dosage compensation (0.5 < Zf:AAf < 1) and dosage balance (0.5f:ZZm<1). The underlying mechanism remains largely elusive. Here, we quantified gene expression for a total of 15 male and female Eurasian crows (Corvus (corone) spp.) raised under common garden conditions. In addition, we characterized aspects of the regulatory landscape quantifying genome-wide ATAC-seq and 5mC methylation profiles. Partial dosage compensation was explained by female upregulation of Z-linked genes accompanied by increased chromatin accessibility on the female Z chromosome. 5mC methylation was strongly reduced in open chromatin-regions and GC islands and showed chromosome-, but no sex-specific variation. With the exception of the pseudo-autosomal region (PAR), female upregulation of gene expression was evenly spread across the Z chromosome without evidence for regional epigenetic regulation, as has for example been suggested for the male hypermethylated region (MHM) in chicken. Our results support the hypothesis that partial dosage compensation in female heterogametic systems is subject to chromosome-wide, epigenetic control mediated by differential chromatin accessibility between the sexes.

opencc-by-4.0Oct 2021View details →

Data for: Compensating for a stressful pregnancy? Glucocorticoid treatment during gravidity reduces metabolic rate in female fence lizards post-parturition (In press: Hormones and Behavior)

This dataset accompanies the paper "Compensating for a stressful pregnancy? Glucocorticoid treatment during gravidity reduces metabolic rate in female fence lizards post-parturition" (In press: Hormones and Behavior). A READ_ME/metadata explanation is available in Sheet 1. Address any queries to Dr. K. MacLeod, kirstyjmacleod@gmail.com. Abstract: Reproduction is a critical part of an animal’s life history, but one which incurs significant costs to survival and future reproductive potential. These physiological consequences are likely to be influenced by context – for example, if an individual is subject to environmental stressors, physiological and behavioral changes associated with reproduction may be altered. Glucocorticoids, hormones produced as part of the physiological response to stressors, may alter how reproduction affects female physiology and behavior, and therefore the outcomes of reproductive trade-offs. Glucocorticoids prioritize immediate survival over reproduction, for example through changes in immune function, metabolic rate, and foraging, which may reduce energy expenditure or increase energy gain. However, we previously found that female eastern fence lizards (Sceloporus undulatus) experiencing elevated glucocorticoid levels during gestation were nevertheless able to maintain reproductive output and body condition. Here we investigate compensatory mechanisms by which eastern fence lizard females may maintain reproduction under experimental increases in a glucocorticoid, corticosterone (CORT). We found that, although CORT-treated females had similar immune function and behavior, they had reduced metabolic rates 3-5 days post-parturition compared to control females. Given that CORT-treated females spent a similar time basking and had equal food intake compared to control females, we suggest that the reduced metabolic rate is a mechanism by which CORT-treated females maintain their energy balance and reduce the energetic costs of gestation during periods of stress. This study suggests that physiological responses to reproduction may be context-dependent and could act to minimize costs of reproduction in situations where CORT is elevated (such as during periods of environmental stress).

opencc-zeroNov 2022View details →

Functional impact of subunit composition and compensation on Drosophila melanogaster nicotinic receptors: Targets of neonicotinoids

Neonicotinoid insecticides target insect nicotinic acetylcholine receptors (nAChRs) and their adverse effects on non-target insects are of serious concern. We recently found that cofactor TMX3 enables robust functional expression of insect nAChRs in Xenopus laevis oocytes and showed that neonicotinoids (imidacloprid, thiacloprid, and clothianidin) exhibited agonist actions on some nAChRs of the fruit fly (Drosophila melanogaster), honeybee (Apis mellifera) and bumblebee (Bombus terrestris) nAChRs with more potent actions on the pollinator nAChRs. However, other subunits from the nAChR family remain to be explored. We show that the Dα3 subunit co-exists with Dα1, Dα2, Dβ1, and Dβ2 subunits in the same neurons of adult D. melanogaster, thereby expanding the possible nAChR subtypes in these cells alone from 4 to 12. The presence of Dα1 and Dα2 subunits reduced the affinity of imidacloprid, thiacloprid, and clothianidin for nAChRs expressed in Xenopus laevis oocytes, whereas the Dα3 subunit enhanced it. RNAi targeting Dα1, Dα2, or Dα3 in adults reduced expression of targeted subunits but commonly enhanced Dβ3 expression. Also, Dα1 RNAi enhanced Dα7 expression, Dα2 RNAi reduced Dα1, Dα6, and Dα7 expression and Dα3 RNAi reduced Dα1 expression while enhancing Dα2 expression, respectively. In most cases, RNAi treatment of either Dα1 or Dα2 reduced neonicotinoid toxicity in larvae, but Dα2 RNAi enhanced neonicotinoid sensitivity in adults reflecting the affinity-reducing effect of Dα2. Substituting each of Dα1, Dα2, and Dα3 subunits by Dα4 or Dβ3 subunit mostly increased neonicotinoid affinity and reduced efficacy. Therefore, functional expression studies and RNAi targeting of subunits show that neonicotinoid action and toxicity involve the integrated actions of multiple nAChR subunit combinations, counseling caution in interpreting toxicity to insects by subunit gene modification alone.

opencc-by-4.0Jul 2022View details →

Strong lateral exchange coupling and current-induced switching in single-layer ferrimagnetic films with patterned compensation temperature

Open data for "Strong lateral exchange coupling and current-induced switching in single-layer ferrimagnetic films with patterned compensation temperature"

opencc-by-4.0Feb 2023View details →

data from "Temperate bats may alter calls to partially compensate for weather-induced changes in detection distance"

Echolocation call parameters of three species of European bats collected between 2017-2019, recorded with a microphone array. This dataset is associated to the manuscript "Temperate bats may alter calls to partially compensate for weather-induced changes in detection distance". Included is the R script used for statistical analyses, as well as the R script used to model detection distances of different targets by bats across weather conditions.

opencc-zeroMar 2023View details →

Carryover effects in a sea star: Juvenile resource availability does not compensate for a poor larval environment

Carryover effects are widespread in nature and can link early-life experiences to the regulation of populations. However, for organisms with complex life cycles, it is unclear whether offspring can overcome negative early-life experiences when provided with abundant post-metamorphic resources. We tested this by rearing larvae of the keystone sea star Asterias forbesi, under high or low food conditions, and then reared the juveniles for 2–3 weeks under one of four food treatments. Larvae reared under low food conditions took longer to reach metamorphosis and settled as smaller juveniles with fewer spines. For early settlers (mean age at settlement = 24.0 d), carryover effects of low larval food significantly reduced post-metamorphic size, mussel consumption and growth. However for late settlers (mean age at settlement = 29.3 d), there were no carryover effects of larval food availability detected post-metamorphosis. The differences between early and late settlers may indicate a trade-off between larval duration and the presence of carryover effects. Our data suggest that carryover effects mediated by body size at settlement could determine post-metamorphic survival, growth, and performance, ultimately impacting the recruitment of this keystone predator.

opencc-zeroJun 2023View details →

Raw data for: Over-eruption in marsupial carnivore teeth: compensation for a constraint

Pronounced over-eruption of the canine teeth, much greater than in eco-morphologically equivalent placental carnivores, occurs with age and growth in Australian marsupial carnivores. Suppression of functional tooth replacement is a characteristic of marsupials and is frequent among diverse placentals, where the primitive therian pattern is two generations of incisor, canine and premolar teeth. Rapid determinate growth is one among multiple hypotheses proposed to explain the loss of tooth replacement in mammals. In this line of reasoning, the animal reaches a sufficient body or jaw size to accommodate adult-sized teeth by the time it requires functional dentition. Marsupial carnivores have a full set of adult anterior teeth at weaning, which erupt into a juvenile jaw that is 25 to 30 % adult size, compared with well grown in placental carnivores. Indeterminate over-eruption of the canine teeth in marsupial carnivores results in increasing canine height and diameter with increasing body size with age, suggesting this is a compensatory mechanism for the constraint of a single generation of anterior teeth. Patterns of over-eruption in different tooth types of marsupial carnivores are consistent with two non-exclusive mechanisms that operate in other mammals, a response to tooth wear and lack of an occlusal partner.

opencc-by-4.0Jul 2023View details →

A triple distinction of cerebellar function for oculomotor learning and fatigue compensation

This depository contains the data and modeling code of the publication  Masselink J., Cheviet, A., Froment-Tilikete, C., Pélisson, D., & Lappe, M. (2023). A triple distinction of cerebellar function for oculomotor learning and fatigue compensation. PLoS Comput Biol Please see the publication for detailed description of experimental and modeling methods. Data are provided in a mat-file, modeling code is provided in m-files (Matlab).

An Exploratory Haemodynamic Study in Patients With Compensated Cirrhosis and Portal Hypertension

ClinicalTrials.gov study NCT01640964. IPD Sharing: Not stated. Countries: 1. Publications: 1.

Assessment of Disability Compensation With the C-LEG COMPACT 2 Knee (Ref. 3C60 et 3C60=ST)

ClinicalTrials.gov study NCT02382991. IPD Sharing: Not stated. Countries: 3. Publications: 11.

closedIPD-NOFeb 2026View details →

Study to Evaluate the Safety and Efficacy of Selonsertib, Firsocostat, Cilofexor, and Combinations in Participants With Bridging Fibrosis or Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (

ClinicalTrials.gov study NCT03449446. IPD Sharing: NO. Countries: 6. Publications: 1.

Phase 3 Study of GSK548470 in Patients With Compensated Chronic Hepatitis B With Poor Response to Other Drugs

ClinicalTrials.gov study NCT01475851. IPD Sharing: Not stated. Countries: 1. Publications: 1.

Phase 3 Study of GSK548470 in Patients With Compensated Chronic Hepatitis B Untreated With Nucleic Acid Analogue

ClinicalTrials.gov study NCT01480284. IPD Sharing: Not stated. Countries: 1. Publications: 1.

controlledIPD-YESFeb 2026View details →

Safety and Efficacy of Selonsertib in Adults With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH)

ClinicalTrials.gov study NCT03053063. IPD Sharing: YES. Countries: 22. Publications: 6.

controlledIPD-YESFeb 2026View details →

Multi-Center Study of the Effects of Simvastatin on Hepatic Decompensation and Death in Subjects Presenting With High-Risk Compensated Cirrhosis

ClinicalTrials.gov study NCT03654053. IPD Sharing: YES. Countries: 1. Publications: 1.

Right Ventricular Compensation With Sotatercept: A Prospective Single Arm Open Label Phase 4 Study to Evaluate the Effects of Sotatercept on Right Ventricular Function in Pulmonary Arterial Hypertensi

ClinicalTrials.gov study NCT06658522. IPD Sharing: UNDECIDED. Countries: 1. Publications: 11.