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784 results for “dermal”
Figure 7 in Comparative morphology of the dermal palate in squamate reptiles, with comments on phylogenetic implications
Figure 7. Three-dimensional high-resolution X-ray computed tomographic (HRXCT) reconstructions of Ophisaurus apodus. A, ventral view; B, sagittal cutaway slice 161; C, transverse cutaway slice 091. Scale bar = 5 mm.
Text-fig. 3. Archaeotetraodon winterbottomi. Specimen NMN- HU-P PI 1995. Details of dermal bifid spinules. in New Material Of The Puffer Fish Archaeotetraodon Winterbottomi Tyler Et Bannikov, 1994 (Tetraodontidae) From The Oligocene Of The Eastern Paratethys
Text-fig. 3. Archaeotetraodon winterbottomi. Specimen NMN- HU-P PI 1995. Details of dermal bifid spinules.
Expression Profile of CD157 Reveals Functional Heterogeneity of Capillaries in Human Dermal Skin
<p>CD157 acts as a receptor, regulating leukocyte trafficking and the binding of extracellular matrix components. However, the expression pattern and the role of CD157 in human blood (BEC) and the lymphatic endothelial cells (LEC) of human dermal microvascular cells (HDMEC), remain elusive. We demonstrated constitutive expression of CD157 on BEC and LEC, in fetal and juvenile/adult skin, in situ, as well as in isolated HDMEC. Interestingly, CD157 epitopes were mostly localized on BEC, co-expressing high levels of CD31 (CD31<sup>High</sup>), as compared to CD31<sup>Low</sup> BEC, whereas the podoplanin expression level on LEC did not affect CD157. Cultured HDMEC exhibited significantly higher numbers of CD157-positive LEC, as compared to BEC. Interestingly, separated CD157<sup>-</sup> and CD157<sup>+</sup> HDMEC demonstrated no significant differences in clonal expansion in vitro, but they showed distinct expression levels of cell adhesion molecules, before and after cytokine stimulation in vitro. In particular, we proved the enhanced and specific adherence of CD11b-expressing human blood myeloid cells to CD157<sup>+</sup> HDMEC fraction, using an in vitro immune-binding assay. Indeed, CD157 was also involved in chemotaxis and adhesion of CD11b/c monocytes/neutrophils in prevascularized dermo-epidermal skin substitutes (vascDESS) in vivo. Thus, our data attribute specific roles to endothelial CD157, in the regulation of innate immunity during inflammation.</p> <p> </p>
Data from: Dermal denticle shedding rates vary between two captive shark species
Open the record for dataset details and reuse information.
AnnData files for "Human dermal fibroblast subpopulations are conserved across single-cell RNA sequencing studies"
<p>AnnData files for "Human dermal fibroblast subpopulations are conserved across single-cell RNA sequencing studies". </p> <p>Includes Joined dataset with all four datasets at once.</p>
Overexpression of VEGF in dermal fibroblast cells accelerates the angiogenesis and wound healing function: in vitro and in vivo studies
<p>Human dermal fibroblasts (Hu02) were transfected by pcDNA3.1(-)-VEGF vector. Following selecting fibroblast cells with hygromycin, recombinant cells were investigated in terms of VEGF expression by quantifying method. We used Real-Time PCR assay to quantitate gene expression of vascular endothelial growth factor from manipulated cells and represented VEGF overexpression.</p> <p>Reverse transcription was performed from 1 μg of total RNA transcribed to complementary DNA (cDNA) through 1 μL of random hexamer primer. The reactions were incubated at 70°C for 5 minutes. After that, 5X RT-buffer, dNTP, and RT-enzyme were added, and the mixtures were incubated at 42°C for 60 minutes and 70°C for 10 minutes. Reverse transcription was performed from 500 ng total RNA using the RT2 First Strand Kit (SA Biosciences). Quantitative real-time PCR was performed (Ampliqon, Denmark) with 40 cycles at 95 oC for 15 seconds and 60 oC for 60 seconds.</p> <p>The normalization and all the data analysis were performed according to RESR and Graph pad-Prism 8 software.<br> For the normalization, it uses the housekeeping gene: β-Actin.<br> Target gene signals normalized to housekeeping genes; 2^-deltaCt, where deltaCt = (Ct_Target − Ct_HKG)].<br> </p>
Data from: Morphology and distribution of scales, dermal ossifications, and other non-feather integumentary structures in non-avialan theropod dinosaurs
<p class="MsoBodyText">Modern birds are typified by the presence of feathers, complex evolutionary innovations that were already widespread in the group of theropod dinosaurs (Maniraptoriformes) that include crown Aves. Squamous or scaly reptilian-like skin is, however, considered the plesiomorphic condition for theropods and dinosaurs more broadly. Here, we review the morphology and distribution of non-feathered integumentary structures in non-avialan theropods covering squamous skin and naked skin as well as dermal ossifications. The integumentary record of non-averostran theropods is limited to tracks, which ubiquitously show a covering of tiny reticulate scales on the plantar surface of the pes. This is consistent also with younger averostran body fossils, which confirm an arthral arrangement of the digital pads. Among averostrans, squamous skin is confirmed in<i> </i>Ceratosauria (<i>Carnotaurus</i>), Allosauroidea (<i>Allosaurus, Concavenator, Lourinhanosaurus</i>), Compsognathidae (<i>Juravenator</i>), and Tyrannosauroidea (<i>Santanaraptor, Albertosaurus, Daspletosaurus, Gorgosaurus, Tarbosaurus, Tyrannosaurus</i>), whereas dermal ossifications consisting of sagittate and mosaic osteoderms are restricted to <i>Ceratosaurus.</i> Naked, non-scale bearing skin is found in the contentious tetanuran <i>Sciurumimus</i>, possibly ornithomimosaurians (<i>Pelecanimimus</i>) and tyrannosauroids (<i>Santanaraptor</i>), and also on the patagia of scansoriopterygids (<i>Ambopteryx, Yi</i>). Scales are surprisingly conservative among non-avialan theropods compared to some dinosaurian groups (e.g., hadrosaurids); however, the limited preservation of tegument on most specimens hinders further interrogation. Scale patterns vary between and/or within body regions in <i>Carnotaurus</i>, <i>Concavenator</i> and <i>Juravenator</i>, and include polarised, snake-like ventral scales on the tail of the latter two genera. Unusual but more uniformly-distributed patterning also occurs in <i>Tyrannosaurus</i>, whereas feature scales are present only in <i>Albertosaurus</i> and <i>Carnotaurus.</i> Few theropods currently show compelling evidence for the cooccurrence of scales and feathers (e.g., <i>Juravenator,</i> <i>Sinornithosaurus</i>), although reticulate scales were probably retained on the mani and pedes of many theropods with a heavy plumage. Feathers and filamentous structures appear to have replaced widespread scaly integuments in maniraptorans<i>.</i> Theropod skin, and that of dinosaurs more broadly, remains a virtually untapped area of study and the appropriation of commonly-used techniques in other palaeontological fields to the study of skin holds great promise for future insights into the biology, taphonomy and relationships of these extinct animals.</p>
Data for: The first description of dermal armour in snakes
<p>Osteoderms, also called dermal armour, often play a role in predator defence. The presence of osteoderms is highly irregularly distributed across the squamate phylogeny and they have not been found in snakes. In this study, we searched for candidate snake species that would benefit from such armour to protect their body, focusing primarily on fossorial species with defensive tail displays. We examined the tail morphology of 27 snake species from different families using micro-computed tomography (µCT) and micro-radiography. We discovered dermal armour in four species of sand boas (Erycidae) that also feature enlarged and highly modified caudal vertebrae. This is the first description of dermal armour in snakes. Ancestral state reconstructions revealed that osteoderms likely evolved once or multiple times in Erycidae. We have not found osteoderms in any other examined snake species. Nevertheless, similar structures are known from unrelated squamate clades, such as gerrhosaurids and geckos. This supports the idea of underlying deep developmental homology. We propose the hypothesis that osteoderms protect sand boas like the "brigandine armour" of medieval warriors. We interpret it as another component of the sand boas' rich defence strategy.</p>
Safety, Effectiveness and Participant Satisfaction Study of a Dermal Filler (of RADIESSE® (+) Lidocaine) in the Treatment of Ageing Signs in the Face
ClinicalTrials.gov study NCT03650387. IPD Sharing: NO. Countries: 1. Publications: 1.
Radiesse® Injectable Dermal Filler for the Treatment of Nasolabial Folds in Persons of Color
ClinicalTrials.gov study NCT01012388. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Renuvion Dermal System for Dermal Resurfacing
ClinicalTrials.gov study NCT04185909. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Visualizing Dermal Micropores With OCT
ClinicalTrials.gov study NCT04867733. IPD Sharing: NO. Countries: 1. Publications: 1.
Gene Expression Study Between Two Dermal Injectables Hydroxylapatite Semi-permanent Filler
ClinicalTrials.gov study NCT05620043. IPD Sharing: NO. Countries: 1. Publications: 1.
StrataGraft® Skin Tissue in the Promotion of Autologous Skin Regeneration of Complex Skin Defects Due to Thermal Burns That Contain Intact Dermal Elements
ClinicalTrials.gov study NCT03005106. IPD Sharing: NO. Countries: 1. Publications: 1.
Profound Dermal and SubQ Cartridges for the Treatment of Cellulite
ClinicalTrials.gov study NCT03078647. IPD Sharing: NO. Countries: 1. Publications: 5.
RCT of Two Noncrosslinked Porcine Acellular Dermal Matrices in Ab Wall Reconstruction
ClinicalTrials.gov study NCT02228889. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Characterization of Dermal Reactions in Pediatric Patients With ADHD Using DAYTRANA
ClinicalTrials.gov study NCT00434213. IPD Sharing: NO. Countries: 1. Publications: 1.
Acellular Dermal Matrix(SureDerm BCS) in Breast-Conserving Surgery for Breast Cancer Patients
ClinicalTrials.gov study NCT07345026. IPD Sharing: NO. Countries: 1. Publications: 2.
Acellular Dermal Matrix in Primary Palatoplasty
ClinicalTrials.gov study NCT01867632. IPD Sharing: NO. Countries: 1. Publications: 1.
The Use of J-Plasma® for Dermal Resurfacing
ClinicalTrials.gov study NCT03286283. IPD Sharing: NO. Countries: 1. Publications: 1.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.