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1,248 results for “epithelium”
◂Fig. 10 Scanning electron microscopy images of Ramisyllis kingghidorahi n. sp., posterior-most regions and epithelium details. A–D Posterior ends. Arrow in C and D points to heavily ciliated anus. E– G Minute crests on the dorsal surface of midbody segments. Arrows point to crests laterally located on the dorsal surface. H Dorsal surface of posterior segments. I Clumps of cilia on dorsal surface of proventricular segments. Arrows pointing to pores in H. Scale bars: 100 µm A, B, I, 50 um C, G, 5 µm D, E,4 µm F, and 3 µm H in Ramisyllis kingghidorahi n. sp., a new branching annelid from Japan
◂Fig. 10 Scanning electron microscopy images of Ramisyllis kingghidorahi n. sp., posterior-most regions and epithelium details. A–D Posterior ends. Arrow in C and D points to heavily ciliated anus. E– G Minute crests on the dorsal surface of midbody segments. Arrows point to crests laterally located on the dorsal surface. H Dorsal surface of posterior segments. I Clumps of cilia on dorsal surface of proventricular segments. Arrows pointing to pores in H. Scale bars: 100 µm A, B, I, 50 um C, G, 5 µm D, E,4 µm F, and 3 µm H
BMP/SMAD1/5 signaling in the endometrial epithelium is essential for receptivity and early pregnancy
<p>The biological processes that control endometrial receptivity and embryo implantation are critical for the successful outcome of pregnancy. The endometrium is the complex inner lining of the uterine wall that is under the cyclical control of estrogen and progesterone and is a site of intimate contact between mother and blastocyst. The bone morphogenetic signaling (BMP) pathway is a highly conserved signaling pathway that controls key cellular processes throughout pregnancy and exerts intracellular effects via the SMAD1/5 transcription factors. To delineate the endometrial compartment–specific roles of BMP signaling, we generated mice with epithelial-specific conditional deletion of SMAD1/5 using Lactoferrin-icre (Smad1flox/flox;Smad5flox/flox;Lactoferrin-cre, "Smad1/5 cKO"). Histological analysis of the reproductive tracts showed that Smad1/5 cKO mice were developmentally normal and displayed no defects in glandular morphology. In fertility analyses, single SMAD1 or SMAD5 deletion had no effect on fertility; however, double-conditional deletion of SMAD1 and SMAD5 resulted in severe subfertility. Timed mating analyses revealed endometrial receptivity defects in the Smad1/5 cKO mice beginning at 3.5 days post coitum (dpc) that perturbed embryo implantation at 4.5 dpc, as demonstrated by the detection of unattached blastocysts in the uterus, decreased COX2 expression, and FOXO1 cytoplasmic mislocalization. We also found that defects that arose during peri-implantation adversely affected embryonic and decidual development at 5.5 and 6.5 dpc. Thus, uterine epithelial BMP/SMAD1/5 signaling is essential during early pregnancy and SMAD1/5 epithelial-specific deletion has detrimental effects on stromal cell decidualization and pregnancy development.</p>
Dataset for "Spatial distribution and physicochemical properties of respirable volcanic ash from the 16-17 August 2006 Tungurahua eruption (Ecuador), and alveolar epithelium response in-vitro" published in GeoHealth
<p>Data Repository for:</p> <p><strong>"Spatial distribution and physicochemical properties of respirable volcanic ash from the 16-17 August 2006 Tungurahua eruption (Ecuador), and alveolar epithelium response <em>in-vitro" </em></strong>published in GeoHealth.<br> </p> <p>Julia Eychenne<sup>1,2*</sup>, Lucia Gurioli<sup>1</sup>, David Damby<sup>3</sup>, Corinne Belville², Federica Schiavi<sup>1</sup>, Geoffroy Marceau<sup>2,4</sup>, Claire Szczepaniak<sup>5</sup>, Christelle Blavignac<sup>5</sup>, Mickael Laumonier<sup>1</sup>, Emmanuel Gardés<sup>1</sup>, Jean-Luc Le Pennec<sup>6,7</sup>, Jean-Marie Nedelec<sup>8</sup>, Loïc Blanchon², Vincent Sapin<sup>2,4 </sup></p> <p><sup>1</sup> Université Clermont Auvergne, CNRS, IRD, OPGC, Laboratoire Magmas et Volcans, F-63000 Clermont-Ferrand, France</p> <p><sup>2</sup> Université Clermont Auvergne, CNRS, INSERM, Institut de Génétique Reproduction et Développement, F-63000 Clermont-Ferrand, France</p> <p><sup>3</sup> U.S. Geological Survey, California Volcano Observatory, Moffett Field, CA, USA</p> <p><sup>4</sup> Biochemistry and Molecular Genetic Department, University Hospital, F-63000 Clermont-Ferrand, France</p> <p><sup>5</sup> Université Clermont Auvergne, UCA PARTNER, Centre Imagerie Cellulaire Santé, F-63000 Clermont-Ferrand, France</p> <p><sup>6</sup> Geo-Ocean, CNRS, Ifremer, UMR6538, F-29280 Plouzané, France</p> <p><sup>7</sup> IRD Office for Indonesia & Timor Leste, Jalan Kemang Raya n°4, Jakarta 12730, Indonesia</p> <p><sup>8</sup> Université Clermont Auvergne, Clermont Auvergne INP, CNRS, ICCFn, F-63000 Clermont-Ferrand, France</p> <p><strong>This repository includes the grainsize distributions of the individual tephra fall samples, the grainsize distribution of the respirable ash sample isolated from F2, the Raman point counting data and individual spectra, the SEM images and EDX maps of the respirable ash sample, the SEM and TEM images of the <em>in-vitro</em> experiments, and the data from the LDH assays, multiplex immunoassays and RT-qPCR.</strong></p>
Biohybrid microrobots regulate colonic cytokine and epithelium barrier in inflammatory bowel disease
<p>Cytokines have been identified as key contributors to the development of inflammatory bowel disease (IBD), yet conventional treatments often prove inadequate and carry substantial side effects. Here, we show an innovative biohybrid robotic system, termed 'algae-MΦNP-robot', for addressing IBD by actively neutralizing colonic cytokine levels. Our approach combines moving green microalgae with macrophage membrane-coated nanoparticles (MΦNPs) to efficiently capture pro-inflammatory cytokines 'on-the-fly'. The dynamic algae-MΦNP-robots outperform static counterparts by enhancing cytokine removal through continuous movement, better distribution, and extended retention in the colon. This system is encapsulated within an oral capsule, which shields it from gastric acidity and ensures functionality upon reaching the targeted disease site. The resulting algae-MΦNP-robot capsule effectively regulates cytokine levels, facilitating the healing of damaged epithelial barriers. It shows markedly improved prevention and treatment efficacy in a mouse model of IBD and demonstrates an excellent biosafety profile. Overall, our biohybrid algae-MΦNP-robot system offers a promising and efficient solution for IBD, addressing cytokine-related inflammation effectively.</p>
Annotation file (gff3) from the killifish, Fundulus rathbuni (gill epithelium)
<p>Annotation, gff3 file of the reference de novo transcriptome assembly from the killifish, Fundulus rathbuni created with the dammit pipeline using the Pfam, Rfam, OrthoDB databases in addition to Fundulus heteroclitus amino acids (RefSeq).</p> <p>Fish were acclimated to either brackish or fresh water then exposed to an acute brackish water challenge. Transcriptome data from gill epithelium tissue were collected. A reference transcriptome assembly was generated from all individuals then used to analyze transcriptional responses to salinity.</p> <p> </p>
Sodium channels enable fast electrical signaling and regulate phagocytosis in the retinal pigment epithelium
<p>This dataset contains all patch clamp, confocal and mass spectrometry datasets of our publication 'Sodium channels enable fast electrical signaling and regulate phagocytosis in the retinal pigment epithelium', published in BMC Biology. The data for each figure (fig 1-7) and supplementary figure (1-3) has been collected to an individual zipped folder. For additional information, please contact the corresponding author (Soile Nymark).</p>
Photic generation of 11-cis-retinal in bovine retinal pigment epithelium
<p>Raw datasets for MS-based RGR identification. For additional information please see: Zhang et al. JBC 2019</p>
Establishment of Biobank of Nasal Epithelium Samples From Healthy Volunteers
ClinicalTrials.gov study NCT06120244. IPD Sharing: YES. Countries: 1. Publications: 2.
Effects on the Olfactory Epithelium and the Olfactory Nerve From Exposure to Diesel Exhaust
ClinicalTrials.gov study NCT07237958. IPD Sharing: NO. Countries: 1. Publications: 1.
Efficacy of CryoBalloon Focal Ablation System on Human Esophageal Barrett's Epithelium
ClinicalTrials.gov study NCT02249975. IPD Sharing: NO. Countries: 1. Publications: 2.
Study of Demarcation Line Depth in Transepithelial Versus Epithelium-off Accelerated Cross-linking (AXL) in Keratocouns
ClinicalTrials.gov study NCT04045626. IPD Sharing: NO. Countries: 1. Publications: 1.
Depth of Necrosis in Normal Cervical Epithelium After 85% Trichloroacetic Acid (TCA) Application
ClinicalTrials.gov study NCT04911075. IPD Sharing: YES. Countries: 1. Publications: 8.
Nasal Epithelium Gene Expression Profiling in Child Respiratory Allergic Disease
ClinicalTrials.gov study NCT00569361. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Airway Epithelium Gene Expression in the Diagnosis of Lung Cancer: AEGIS CLIA
ClinicalTrials.gov study NCT01309087. IPD Sharing: Not stated. Countries: 3. Publications: 2.
High-Risk Breast Duct Epithelium
ClinicalTrials.gov study NCT00028340. IPD Sharing: YES. Countries: 1. Publications: 4.
Customized Crosslinking: Safety and Efficacy in an Epithelium-off Accelerated-pulsated Protocol for Thin Keratoconus
ClinicalTrials.gov study NCT06159881. IPD Sharing: NO. Countries: 1. Publications: 3.
Function of the Pigment Epithelium in Patients With Type 1 Neurofibromatosis
ClinicalTrials.gov study NCT04153344. IPD Sharing: NO. Countries: 1. Publications: 3.
Study of Genic Expression Profiles of the Epithelium of the Nose and Bronchi in Healthy and Allergic Subjects
ClinicalTrials.gov study NCT01923519. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Modeling Bronchial Epithelium Modifications Associated With COPD Using iPS
ClinicalTrials.gov study NCT03181204. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Clinical Study of Subretinal Transplantation of Human Embryo Stem Cell Derived Retinal Pigment Epitheliums in Treatment of Macular Degeneration Diseases
ClinicalTrials.gov study NCT02749734. IPD Sharing: Not stated. Countries: 1. Publications: 1.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.