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149
datasets available to search
ShareScore release 0.7.1
Dataset results
149 results for “glycan”
SUGAR-Seq enables simultaneous detection of glycans, epitopes and the transcriptome in single cells [LN scRNA-seq]
GEO Series GSE166325. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Baseline serum anti-glycan antibodies of 113 subjects in a clinical trial of PROSTVAC-VF, a therapeutic cancer vaccine
GEO Series GSE42184. Gossypium hirsutum; Rhodotorula; Homo sapiens; Bos taurus; Mus musculus; Quercus alba; Pandalus borealis; Bothrops moojeni; Senegalia senegal; Dermestes lardarius; Ovis aries; Megathura crenulata; Frangula alnus; Medicago sativa; Gallus gallus; Pachymenia carnosa. 564 samples. Type: Protein profiling by protein array.
Generation of a monoclonal antibody recognizing the CEACAM glycan structure and inhibiting adhesion using cancer tissue-originated spheroid as an antigen
GEO Series GSE76405. Homo sapiens. 32 samples. Type: Expression profiling by array.
Essential functions of glycans in human epithelia dissected by a CRISPR/Cas9-engineered human organotypic skin model
GEO Series GSE148284. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Interleukin-22 (IL-22) regulates B3GNT7 expression to induce intestinal fucosylation of O-linked glycans
GEO Series GSE154889. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
XBP1s Activation Globally Remodels N-Glycan Structure Distribution Patterns
GEO Series GSE112589. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Ascending colon-derived mucin-type O-glycans form key mucus layers encapsulating microbiota in the colon (RNA-seq)
GEO Series GSE133174. Mus musculus. 30 samples. Type: Expression profiling by high throughput sequencing.
Single-cell glycome and transcriptome profiling uncovers the glycan signature of each cell subpopulation of human iPSC-derived neurons
GEO Series GSE304173. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Overexpression of brain endothelial mucin-type O-glycan biosynthesis promotes brain homeostasis in aged mice
GEO Series GSE268642. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Mutant GNAS drives a pyloric metaplasia with tumor suppressive glycans in intraductal papillary mucinous neoplasia
GEO Series GSE244280. Mus musculus. 36 samples. Type: Expression profiling by high throughput sequencing.
SUGAR-Seq enables simultaneous detection of glycans, epitopes and the transcriptome in single cells [3'RNA-seq]
GEO Series GSE166323. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Analysis of the transcriptome of Bacteroides thetaiotaomicron during growth on complex N-glycan as the sole carbon source
GEO Series GSE129572. Bacteroides thetaiotaomicron VPI-5482. 6 samples. Type: Expression profiling by high throughput sequencing.
SUGAR-Seq enables simultaneous detection of glycans, epitopes and the transcriptome in single cells [TIL scRNA-seq]
GEO Series GSE166326. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
FGF2 induces migration of human bone marrow stromal cells by increasing core-fucosylations on N-glycans of integrins
GEO Series GSE115240. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
Free glycans derived from O-mannosylated glycoproteins suggest the presence of an O-glycoprotein degradation pathway in yeast
GEO Series GSE130332. Saccharomyces cerevisiae. 6 samples. Type: Expression profiling by high throughput sequencing.
Data from: Immunogenicity of glycans on biotherapeutic drugs produced in plant expression systems - the taliglucerase alfa story
Plants are a promising alternative for the production of biotherapeutics. Manufacturing in-planta adds plant specific glycans. To understand immunogenic potential of these glycans, we developed a validated method to detect plant specific glycan antibodies in human serum. Using this assay, low prevalence of pre-existing anti-plant glycan antibodies was found in healthy humans (13.5%) and in glucocerebrosidase-deficient Gaucher disease (GD) patients (5%). A low incidence (9% in naïve patient and none in treatment experienced patients) of induced anti-plant glycan antibodies was observed in GD patients after up to 30 months replacement therapy treatment with taliglucerase alfa, a version of human glucocerebrosidase produced in plant cells. Detailed evaluation of clinical safety and efficacy endpoints indicated that anti-plant glycan antibodies did not affect the safety or efficacy of taliglucerase alfa in patients. This study shows the benefit of using large scale human trials to evaluate the immunogenicity risk of plant derived glycans, and indicates no apparent risk related to anti-plant glycan antibodies.
Dataset for "A Family of Di-Glutamate Mucin Degrading Enzymes that Bridges Glycan Hydrolases and Peptidases"
<p>This dataset provides the classical and QM/MM MD simulation trajectory data to the manuscript:</p><p><strong>A Family of Di-Glutamate Mucin Degrading Enzymes that Bridges Glycan Hydrolases and Peptidases</strong></p><p>The data set contains classical MD simulations of HC7 with substrate peptides, thermodynamics integration (TI) simulations, as well as QM/MM OPES-explore simulations for our manuscript. PDB files for Figure 4f and Figure S21 are also included. A high resolution pdf file of Figure S28 is included, too.</p>
REST-RECT simulations of free N-glycans in solution
<p>Starting structure (.gro file) and 500 ns trajectory for replica 0 (.xtc) of a Man5 glycan, Man9+Glc3 and the complex glycan Fuc1_Neu4 in solution enhanced sampled by the REST-RECT scheme.</p>
Glycan Analysis in Diagnosing Cancer in Women With Ovarian Epithelial Cancer and in Healthy Female Participants
ClinicalTrials.gov study NCT00628654. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Clinical Study to Assess the Effect of Novel Glycans on Nitrogen Metabolism of the Gut in Healthy Subjects
ClinicalTrials.gov study NCT04603378. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.