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datasets available to search
ShareScore release 0.9.0
Dataset results
192 results for “glycosylation”
Immunologic Effects of Supplemental Monosaccharide and Nucleoside Derivatives in Patients With Inherited Disorders of Glycosylation
ClinicalTrials.gov study NCT02511041. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Validation of the IgA1 Detection Method With Gradient Glycosylation by Mass Spectrometry as a Potential Marker of Renal Involvement in Pediatric Rheumatoid Purpura
ClinicalTrials.gov study NCT04655378. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Glycosylation in Patients With Galactosaemia
ClinicalTrials.gov study NCT02218632. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Using D-Galactose as a Food Supplement in Congenital Disorders of Glycosylation
ClinicalTrials.gov study NCT02955264. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Glycosylated Hemoglobin and Risk of Perioperative Major Cardiovascular Events in Diabetic Patients Undergoing Coronary Bypass Revascularization (HbA1c)
ClinicalTrials.gov study NCT03590223. IPD Sharing: Not stated. Countries: 1. Publications: 0.
First Trimester Glycosylated Haemoglobin Und Plasma Glucose in Women at High Risk for Gestational Diabetes
ClinicalTrials.gov study NCT02139254. IPD Sharing: Not stated. Countries: 1. Publications: 1.
0 ns and 75 ns configurations of glycosylated ACE2-FC and its interaction with SARS-CoV-2 binding domains
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Short-term treatment of golden retriever muscular dystrophy (GRMD) dogs with rAAVrh74.MCK.GALGT2 induces muscle glycosylation and utrophin expression but has no significant effect on muscle strength
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Reactive extraction of fructose for efficient separation of sucrose-derived glucosides produced by enzymatic glycosylation
<p>We provide here the underlying data of the scientific publication "Reactive extraction of fructose for efficient separation of sucrose-derived glucosides produced by enzymatic glycosylation". Please find the abstract below:</p> <p>The disaccharide sucrose (α-D-glucopyranosyl-1,2-β-D-fructofuranoside) is a highly efficient donor substrate for enzymatic glucosylation reactions. A large number of commercially relevant glucosides are produced via this general route. Every sucrose-based glucosylation involves co-production of D-fructose in amounts corresponding to the target glucoside. A separation technology for selective removal, and efficient recovery, of the D-fructose co-product would be highly desirable as a generic platform for downstream process development. Here, we demonstrate organoboronate-complex reactive extraction of D-fructose into an 1-octanol/hexane (4/1, v/v) solvent using methyltrioctyl ammonium chloride as phase transfer catalyst and extractant. We show separation of the D-fructose co-product (100 mM) from equimolar mixture with 2-α-D-glucosyl-glycerol, a cosmetic ingredient that is manufactured industrially from sucrose and glycerol using sucrose phosphorylase. With the main parameters of extraction, stripping and organic phase recycling identified and their effect on product/co-product yield and purity characterized, we developed a three-step extraction process with alternating extraction and stripping stages that removed the D-fructose efficiently at 50 ml operating scale. 2-α-D-glucosyl-glycerol and D-fructose were cleanly separated and obtained in excellent purity (≥90%) at a recovery of 90% and 83%, respectively. Reactive extraction appears to be faster and more selective and resource-efficient than applicable alternatives for separation, including chromatography and membrane nanofiltration. Thus, the established extraction process is promising for industrial application. It could be generically useful to separate D-fructose from glucosides</p>
Dataset associated to Tailored glycosylated anode surfaces: Addressing the exoelectrogen bacterial community via functional layers for microbial fuel cell applications
<p>This file contains the dataset associated to the published research article "<a href="https://www.sciencedirect.com/science/article/pii/S1567539420302887">Tailored glycosylated anode surfaces: Addressing the exoelectrogen bacterial community via functional layers for microbial fuel cell applications</a>". The dataset contains Atomic Force Microscopy, electrochemistry, Microbial Fuel Cells power output and water contact angle raw data from their relative instruments. This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. <a href="https://www.sciencedirect.com/science/article/pii/S1567539420302887#gp005">799175</a> (HiBriCarbon). The results of this publication reflect only the authors' view and the Commission is not responsible for any use that may be made of the information it contains. This publication has also emanated from research conducted with the financial support of Science Foundation Ireland under Grant No. <a href="https://www.sciencedirect.com/science/article/pii/S1567539420302887#gp010">13/CDA/2213</a>. The authors also thank the France-Ireland PHC ULYSSES programme for support, project 36028UB. JAB acknowledges support from the Irish Research Council under Grant No. <a href="https://www.sciencedirect.com/science/article/pii/S1567539420302887#gp015">GOIPG/2014/399</a>. </p>
Data from: Generation of a monoclonal antibody recognizing the heavily glycosylated CD45 Protein and its application on identifying circulating tumor cells
Here, we provide direct evidence that using recombinant proteins expressed in eukaryotic cells as antigen is a practical way to generate monoclonal antibodies (mAbs) against heavily glycosylated proteins. Heavily glycosylated proteins are typically difficult targets for mAb generation, being limited by unsatisfactory affinity and low specificity. Using the heavily glycosylated CD45 protein as an example, we demonstrate the entire process of expressing the protein in eukaryotic cells and using it as an antigen to generate CD45-targeting mAbs in mice. The mAbs generated showed robust affinity and specificity, which are crucial factors for differentiate circulating tumor cells from white blood cells in human breast cancer patient samples. Only 1 cell fusion and 2 cyclic sub-cloning steps were necessary before mAbs with satisfactory performance were obtained.
Fig. 1 in Insulin-mimetic activity of 23-glycosyl oleanane triterpenoids isolated from Gymnema latifolium
Fig. 1. Chemical structures of isolated compound 1⎯9 from Gymnema latifolium.
Fig. 3 in Insulin-mimetic activity of 23-glycosyl oleanane triterpenoids isolated from Gymnema latifolium
Fig. 3. NOESY (dotted lines) correlations of compound 1 and 7.
Heterogeneous glycosylation and methylation of the Aeromonas caviae flagellin.
<p>Manual analysis of A. caviae FlaB glycopepetides</p>
Fig. 6 in Glycosylated constituents isolated from the trunk of Abies holophylla and their anti-inflammatory and neurotrophic activity
Fig. 6. SAR study on the five cases of isolated compounds for antineuroinflammatory activity.
Fig. 1 in Glycosylated constituents isolated from the trunk of Abies holophylla and their anti-inflammatory and neurotrophic activity
Fig. 1. Chemical structures of 1–31.
Fig. 4 in Molecular networking-driven isolation of 8 -Glycosylated biscoumarins from Cruciata articulata
Fig. 4. Proposed fragmentation pathway of compounds 1 and 4; positive mode.
Fig. 3 in Molecular networking-driven isolation of 8 -Glycosylated biscoumarins from Cruciata articulata
Fig. 3. Selected HMBC (solid arrows) and NOESY (dashed arrows) correlations for compounds 1 and 3.
Fig. 1 in Antioxidant activity and mechanism of dihydrochalcone C-glycosides: Effects of C-glycosylation and hydroxyl groups
Fig. 1. Molecular structures and atomic numbering of the studied dihydrochalcones (DHCs).
Fig. 2 in Antioxidant activity and mechanism of dihydrochalcone C-glycosides: Effects of C-glycosylation and hydroxyl groups
Fig. 2. Double HAT mechanism in ethanol for ASP.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.