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Figure 2 in Taxonomic synthesis of the eastern North American millipede genus Pseudopolydesmus (Diplopoda: Polydesmida: Polydesmidae), utilizing high-detail ultraviolet fluorescence imaging

Figure 2. Pseudopolydesmus erasus, adult male habitus, lateral view (FMNH INS3120685).

opencc-by-4.0Mar 2019View details →

Image Synthesis with a Convolutional Capsule Generative Adversarial Network- Prepared Data

A set of prepared datasets for running experiments to replicate paper (see below). List of data: Training capspix2pix: <ul> <li>crops256.zip - folder containing 256x256 crops from the original dataset for training capspix2pix. Images are in the "train/original" folder, and labels are in the "train/mask" folder.</li> <li>syn256_x_data_val.npy + syn256_y_data_val.npy + syn256_y_points_data_val.npy (images + labels + centrelines) - validation synthetic dataset, used while training capspix2pix for plotting</li> </ul> Training u-net: <ul> <li>capspix2pix_AR_data_train.npy + capspix2pix_AR_mask_train.npy (images + labels) - data generated from a capspix2pix model from real labels</li> <li>capspix2pix_SSM_data_train.npy + capspix2pix_AR_mask_train.npy (images + labels) - data generated from a capspix2pix model from synthetic labels</li> <li>PBAM_SSM_data_train.npy + PBAM_SSM_mask_train.npy (images + labels) - data generated from PBAM (Physics-based model) for training u-net</li> <li>pix2pix_AR_data_train.npy + pix2pix_AR_mask_train.npy (images + labels) - data generated from a pix2pix model from real labels for training u-net</li> <li>pix2pix_SSM_data_train.npy + pix2pix_SSM_mask_train.npy (images + labels) - data generated from a pix2pix model from synthetic labels for training u-net</li> <li>real_data_data_train.npy + real_data_mask_train.npy (images + labels) - augmented real dataset for training u-net</li> </ul> Testing u-net: <ul> <li>org64_data_test.npy + org64_mask_test.npy (images + labels) - crops from original test dataset for testing u-net</li> </ul> Interpolation: <ul> <li>crops256_inter_data_train.npy + crops256_inter_mask_train.npy (images + labels) - example data for interpolation</li> </ul> Please cite the following paper when using this dataset: Bass, C., Dai, T., Billot, B.,  Arulkumaran, K., Creswell, A., Clopath, C., De Paola, V., and Bharath, A. A., 2019. “Image synthesis with a convolutional capsule generative adversarial network,” Medial Imaging with Deep Learning. See Github page for further instructions: https://github.com/CherBass/CapsPix2Pix

opencc-by-4.0Feb 2023View details →

Data collection of toy horses and zebras for multi-modal image synthesis

Motivated by building a live demonstration of horse-to-zebra synthesis, we created our own dataset consisting of images of different toy horses and zebras. We used a wide variety of backgrounds, camera angles and lighting settings. In addition, images were also created in which the toy animals were held in the hand to better demonstrate synthesis in front of the camera.  Besides the raw image and video footage, we prepared different compilations of data in form of datasets. Following the horse-to-zebra synthesis by Zhu et al. in the paper "Unpaired Image-to-Image Translation using Cycle-Consistent Adversarial Networks", we partially adopted the horse2zebra dataset from real horses and zebras in our datasets.

opencc-by-4.0Jul 2023View details →

Synthesis and preclinical evaluation of a novel fluorine-18 labeled small-molecule PET radiotracer for imaging of CXCR3 receptor in mouse models of atherosclerosis

Background CXCR3 is a chemokine receptor and is expressed in innate and adaptive immune cells. It promotes the recruitment of T-lymphocytes and other immune cells to the inflammatory site in response to the binding of cognate chemokines. Upregulation of CXCR3 and its chemokines has been found during atherosclerotic lesion formation. Therefore, detection of CXCR3 by positron emission tomography (PET) radiotracer can be a useful tool for detecting the development of atherosclerosis in a noninvasive manner. Herein, we report the synthesis, radiosynthesis, and characterization of a novel fluorine-18 (F-18, 18F) labeled small-molecule radiotracer for the imaging of the CXCR3 receptor in mouse models of atherosclerosis. Results The reference standard 1 and its precursor 9 were synthesized over 5 steps from starting materials in good to moderate yields. The measured Ki values of CXCR3A and CXCR3B were 0.81 ± 0.02 nM and 0.31 ± 0.02 nM, respectively. [18F]1 was prepared by a two-step radiosynthesis with a decay-corrected radiochemical yield of 13 ± 2%, radiochemical purity > 99%, and specific activity of 44.4 ± 3.7 GBq/μmol at the end of synthesis (n = 6). The baseline studies showed that [18F]1 displayed high uptake in the atherosclerotic aorta and brown adipose tissue in Apolipoprotein E (ApoE) knockout (KO) mice fed with a high-fat diet over 12 weeks. The uptake of [18F]1 in these regions was reduced significantly in self-blocking studies, demonstrating CXCR3 binding specificity. Contrary to this, no significant differences in uptake of [18F]1 in the abdominal aorta of C57BL/6 control mice fed with a normal diet were observed in both baseline and blocking studies, indicating increased CXCR3 expression in atherosclerotic lesions. Immunohistochemistry studies demonstrated that [18F]1-positive regions were correlated with CXCR3 expression, but some atherosclerotic plaques with significant size were not detected by [18F]1, and their CXCR3 expressions were minimal. Conclusion [18F]1 was synthesized with good radiochemical yield and high radiochemical purity. In PET imaging studies, [18F]1 displayed CXCR3-specific uptake in the atherosclerotic aorta in ApoE KO mice. [18F]1 visualized CXCR3 expression in different regions in mice aligned with the tissue histology studies. Taken together, [18F]1 is a potential PET radiotracer for imaging CXCR3 in atherosclerosis.

ClinicalTrials.gov24/100

Imaging Oxidative Metabolism and Neurotransmitter Synthesis in the Human Brain

ClinicalTrials.gov study NCT03849963. IPD Sharing: NO. Countries: 1. Publications: 0.

closedIPD-NOFeb 2026View details →

ClinicalTrials.gov24/100

MR Image Synthesis With Low Gadobutrol Dose and AI

ClinicalTrials.gov study NCT06224543. IPD Sharing: NO. Countries: 1. Publications: 0.

closedIPD-NOFeb 2026View details →

Figure 28 in Taxonomic synthesis of the eastern North American millipede genus Pseudopolydesmus (Diplopoda: Polydesmida: Polydesmidae), utilizing high-detail ultraviolet fluorescence imaging

Figure 28. Gonopod of Pseudopolydesmus caddo. Holotype (USNM, ultraviolet enhancement). A, right gonopod, ectal view. B, right gonopod, medial view.

Figure 6 in Taxonomic synthesis of the eastern North American millipede genus Pseudopolydesmus (Diplopoda: Polydesmida: Polydesmidae), utilizing high-detail ultraviolet fluorescence imaging

Figure 6. The characteristic prefemoral bulge in males of Pseudopolydesmus, and comparison of walking legs in Pseudopolydesmus and Polydesmus (scanning electron micrograph). A, adult male Pseudopolydesmus erasus, left leg 9, with characteristically large prefemoral bulge and thickened femur (FMNH INS3120685). B, adult female Ps. erasus, right leg 12, without prefemoral bulge (FMNH INS3120685). C, adult male Polydesmus inconstans, right leg 14, with slight prefemoral bulge and thickened femur (FMNH INS4265).

Figure 14 in Taxonomic synthesis of the eastern North American millipede genus Pseudopolydesmus (Diplopoda: Polydesmida: Polydesmidae), utilizing high-detail ultraviolet fluorescence imaging

Figure 14. Gonopod of Pseudopolydesmus canadensis (FMNH INS6934, scanning electron micrograph). A, left gonopod, ectal view. B, left gonopod, medial view. Both images mirrored to appear as right gonopod. Cannula removed.

Figure 1 in Taxonomic synthesis of the eastern North American millipede genus Pseudopolydesmus (Diplopoda: Polydesmida: Polydesmidae), utilizing high-detail ultraviolet fluorescence imaging

Figure 1. Two live examples of Pseudopolydesmus. A, Pseudopolydesmus serratus, live adult male, dorsal view (VTEC MPE01173). B, Pseudopolydesmus paludicolus, live adult female, dorsal view (VTEC MPE01167).

Figure 7 in Taxonomic synthesis of the eastern North American millipede genus Pseudopolydesmus (Diplopoda: Polydesmida: Polydesmidae), utilizing high-detail ultraviolet fluorescence imaging

Figure 7. Sternal tubercles in male Pseudopolydesmus canadensis, ventral view, body rings 4–8 (FMNH INS6934, ultraviolet enhancement). Visible body rings (BR4–8) and their corresponding leg pairs (LP3–11) and gonopods (GPs) are labelled. Also note the characteristic silhouette of the gonopods of Ps. canadensis, with processes e2 and e3 sharing a narrow stalk.