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57
datasets available to search
ShareScore release 0.9.0
Dataset results
57 results for “immune system and cancer”
Systemic and Tumor Immune Response During Pelvic (Chemo)Radiation and/or Brachytherapy for Cervical Cancer
ClinicalTrials.gov study NCT06804135. IPD Sharing: NO. Countries: 1. Publications: 0.
Acupuncture for the Immune System in Radiation Cancer Patients
ClinicalTrials.gov study NCT01422928. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study of Galunisertib on the Immune System in Participants With Cancer
ClinicalTrials.gov study NCT02304419. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Safety Study of Specific Tumor Target Drug Plus Immune System Therapy in Patients With Kidney Cancer
ClinicalTrials.gov study NCT00440973. IPD Sharing: NO. Countries: 1. Publications: 0.
Reconstitution of a Human Immune System in a Patient Derived Xenograft (PDX) Model of Genitourinary (GU) Cancers
ClinicalTrials.gov study NCT03134027. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Pulse Radiotherapy to Overcome Metastatic Immune System Evasion in Lung Cancer
ClinicalTrials.gov study NCT06622174. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Monitoring systemic immune responses to checkpoint inhibition in breast cancer reveals host responses and mechanisms of resistance
GEO Series GSE293819. Mus musculus. 142 samples. Type: Expression profiling by high throughput sequencing.
Prior antibiotic administration disrupts outcomes of PD-1 blockade in advanced gastric cancer by altering gut microbiome and systemic immune response
GEO Series GSE229379. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing; Other.
TFPI alpha and beta regulate mRNAs involved in cancer biology and in the immune system
GEO Series GSE30037. Homo sapiens. 9 samples. Type: Expression profiling by array.
Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer [Mammary fat pad, MFP]
GEO Series GSE174044. Mus musculus. 23 samples. Type: Expression profiling by high throughput sequencing.
The humoral immune system has a key prognostic impact in node-negative breast cancer
GEO Series GSE11121. Homo sapiens. 200 samples. Type: Expression profiling by array.
Immune System Modulation with Oral Vancomycin in combination with Stereotactic Body Radiotherapy (SBRT) for medically inoperable Early-Stage Non-small Cell Lung Cancer
GEO Series GSE277984. Homo sapiens. 17 samples. Type: Expression profiling by high throughput sequencing.
Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer
GEO Series GSE174055. Mus musculus. 39 samples. Type: Expression profiling by high throughput sequencing.
A novel breast cancer therapeutic strategy through Hsp90 inhibition and activation of the immune system
GEO Series GSE168875. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
The Immune and Endocrine Systems in Chronic Non-cancer Patients Treated With Opioids
ClinicalTrials.gov study NCT02277080. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer [tumor]
GEO Series GSE174053. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
Proton Irradiation Impacts Age Driven Modulations of Cancer Progression Influenced by Immune System Transcriptome Modifications from Splenic Tissue
Age plays a crucial role in the interplay between tumor and host; with further perturbations induced by irradiation. Proton irradiation on tumors induces biological modulations including inhibition of angiogenic and immune factors critical to ''hallmark'' processes impacting tumor development, in addition to physical targeting advantages. These advantages have provided promising results for proton therapy in cancer. Additionally, protons have implications for carcinogenesis risk of space travel (due to the high proportion of high energy protons in space radiation). Through a systems biology approach, we investigated how host tissue (i.e. splenic tissue) of tumor-bearing mice is altered with age, with or without whole-body proton exposure. Transcriptome analysis was performed on splenic tissue from adolescent (68 day) versus old (736 day) C57BL/6 male mice injected with Lewis lung carcinoma cells with or without three fractionations of 0.5Gy (1GeV) proton irradiation. Global transcriptome analysis indicated that proton irradiation of adolescent hosts caused significant signaling changes within splenic tissues that support carcinogenesis within the mice, as compared to old subjects. Increases in cell cycling and immunosuppression in irradiated adolescent hosts with CDK2, MCM7, CD74, and RUVBL2 as the key players were involved in the regulatory changes in host environment response (i.e. spleen). These results suggest a significant biological component to proton irradiation, operative through host age, that would indicate a modulation of host's ability to support carcinogenesis in adolescence and the bestowal of resistance to immunosuppression, carcinogenesis, and genetic perturbation by old age.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.