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544 results for “integrated model”
Figure 1 in Integrating landscape simulation models with economic and decision tools for invasive species control
Figure 1. Example state and transition simulation model for an invasive species. Landscape change is captured by defining the processes (transitions) that can move a cell from one state to another. These include both natural transitions (e.g., species dispersal, establishment, growth, fire, disturbance) and management transitions (e.g., inventory, treatment, and other activities related to invasion control). In this example, modified from Jarnevich et al. (2015), each box represents the state of a simulation cell with respect to invasive species cover (uninvaded, <5% cover, 5–50% cover, or> 50% cover; left to right) and detection (undetected or detected; top to bottom). The different color-coded arrows represent different types of transitions including growth (invasion, establishment, spread), detection (failure and success), and management (treatment and maintenance failure and success). Solid lines represent success; dotted lines represent failure.
Data from: Integrating genomic data and simulations to evaluate alternative species distribution models and improve predictions of glacial refugia and future responses to climate change
<p>Climate change poses a threat to biodiversity, and it is unclear whether species can adapt to or tolerate new conditions, or migrate to areas with suitable habitats. Reconstructions of range shifts that occurred in response to environmental changes since the last glacial maximum from species distribution models (SDMs) can provide useful data to inform conservation efforts. However, different SDM algorithms and climate reconstructions often produce contrasting patterns, and validation methods typically focus on accuracy in recreating current distributions, limiting their relevance for assessing predictions to the past or future. We modeled historically suitable habitat for the threatened North American tree green ash (<em>Fraxinus pennsylvanica</em>) using 24 SDMs built using two climate models, three calibration regions, and four modeling algorithms. We evaluated the SDMs using contemporary data with spatial block cross-validation and compared the relative support for alternative models using a novel integrative method based on coupled demographic-genetic simulations. We simulated genomic datasets using habitat suitability of each of the 24 SDMs in a spatially-explicit model. Approximate Bayesian Computation (ABC) was then used to evaluate the support for alternative SDMs through comparisons to an empirical population genomic dataset. Models had very similar performance when assessed with contemporary occurrences using spatial cross-validation, but ABC model selection analyses consistently supported SDMs based on the CCSM climate model, an intermediate calibration extent, and the generalized linear modeling algorithm. Finally, we projected the future range of green ash under four climate change scenarios. Future projections using the SDMs selected via ABC suggest only minor shifts in suitable habitat for this species, while some of those that were rejected predicted dramatic changes. Our results highlight the different inferences that may result from the application of alternative distribution modeling algorithms and provide a novel approach for selecting among a set of competing SDMs with independent data.</p>
Prototyping 3D Virtual Learning Environments with X3D-based Content and Visualization Tools-Figure 7. The HTML source (partial) code, integrating the X3D model
<p>To integrate the model into a web page, a model conversion to X3D format and an X3DOM output under the form of an HTML5 encoded webpage (Figure 7) were needed. Instant Reality distribution provides a command line transcoding tool, named Avalon Optimizer (aopt), that was used to convert a VRML format (wrl extension) of the model to X3D. </p>
District heating modelling data for the publication "Integration of feed flow temperatures in unit commitment models of future district heating systems"
<p>Modelling data for a district heating system model which has been used for the publication "Integration of feed flow temperatures in unit commitment models of future district heating systems" on the 4th Generation District Heating (4GDH) conference 2018.</p>
Pol III modeling data and scripts using the Integrative Modeling Platform
<p>This repository contains the data obtained running the Integrative modeling platform with crosslinks and cryoem data, on the RNA Pol III system.</p>
Fig. 3 in Investigating the pathogens associated with Dermacentor nuttalli and its global distribution: A study integrating metagenomic sequencing, meta-analysis and niche modeling
Fig. 3. Prevalence of pathogens associated with D. nuttalli. If there was only one study included in a certain pathogen, the positive rate would be calculated by the positive number of ticks divided by the total number of detected ticks, and without the 95% confidence interval. If there were more studies, the positive rate and 95% confidence interval would be calculated by meta-analysis.
Fig. 2 in Investigating the pathogens associated with Dermacentor nuttalli and its global distribution: A study integrating metagenomic sequencing, meta-analysis and niche modeling
Fig. 2. Study design and data sources of the meta-analysis. A comprehensive meta-analysis was performed to evaluate D. nuttalli's potential threats based on detected pathogens and geographical distribution positions. The database of D. nuttalli was constructed from four sources, including field surveys, literature review, a reference book, and an online biodiversity database (Global Biodiversity Information Facility, GBIF, https://www.gbif.org).
Fig. 1 in Investigating the pathogens associated with Dermacentor nuttalli and its global distribution: A study integrating metagenomic sequencing, meta-analysis and niche modeling
Fig. 1. Relative pathogen abundance of four D. nuttalli samples and the phylogenomic analysis of four Rickettsia genomes. (A) Pathogen abundance at the family level. (B) Pathogen abundance at the genus level. (C) The phylogenetic tree of four Rickettsia assemblies. The phylogenetic tree of four Rickettsia assemblies (Rickettsia conorii subsp. raoultii str XinjiangF1, Rickettsia conorii subsp. raoultii str XinjiangF2, Rickettsia conorii subsp. raoultii str XinjiangF3, and Rickettsia conorii subsp. raoultii str XinjiangM1) was built with 28 other publicly available established or proposed Rickettsiales species. The tree was inferred by IQ-TREE based on 277 single-copy orthologs identified by OrthoFinder. Anaplasma phagocytophilum and Ehrlichia ruminantium were two outgroup species.
Fig. 5 in Investigating the pathogens associated with Dermacentor nuttalli and its global distribution: A study integrating metagenomic sequencing, meta-analysis and niche modeling
Fig. 5. Global potential distribution of D. nuttalli. The red area indicates greater possibilities of suitability for D. nuttalli, while the blue area is less likely to be suitable for D. nuttalli.
Fig. 4 in Investigating the pathogens associated with Dermacentor nuttalli and its global distribution: A study integrating metagenomic sequencing, meta-analysis and niche modeling
Fig. 4. Geographical distribution of D. nuttalli. D. nuttalli lived mainly between 23◦–53◦ latitude and 76◦–133◦ longitude in the Northern Hemisphere. Triangles represent the locations in prefecture-level regions, while circles represent the distribution locations in county-level regions. The green circles represent points from GBIF, the yellow circles are points from literature, the purple circles represent the points from the field survey and the blue points are points from a reference book. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Real-time monitoring of a 3D blood-brain barrier model maturation and integrity with a sensorized microfluidic device
<p><span>A significant challenge in the treatment of central nervous system (CNS) disorders is represented by the presence of the blood-brain barrier (BBB), a highly selective membrane that regulates molecular transport and restricts the passage of pathogens and therapeutic compounds. Traditional <em>in vivo</em> models are constrained by high costs, lengthy experimental timelines, ethical concerns, and interspecies variations. <em>In vitro</em> models, particularly microfluidic BBB-on-a-chip devices, have been developed to address these limitations. These advanced models aim to more accurately replicate human BBB conditions by incorporating human cells and physiological flow dynamics. In this framework, here we developed an innovative microfluidic system that integrates thin-film electrodes for non-invasive, real-time monitoring of BBB integrity using electrochemical impedance spectroscopy (EIS). EIS measurements showed frequency-dependent impedance changes, indicating BBB integrity and distinguishing well-formed from non-mature barriers. The data from EIS monitoring was confirmed by permeability assays performed with a fluorescence tracer. The model incorporates human endothelial cells in a vessel-like arrangement to mimic the vascular component and three-dimensional cell distribution of human astrocytes and microglia to simulate the parenchymal compartment. By modeling the BBB-on-a-chip with an equivalent circuit, a more accurate trans-endothelial electrical resistance (TEER) value was extracted. The device demonstrated successful BBB formation and maturation, confirmed through live/dead assays, immunofluorescence and permeability assays. Computational fluid dynamics (CFD) simulations confirmed that the device mimics <em>in vivo</em> shear stress conditions. Drug crossing assessment was performed with two chemotherapy drugs: doxorubicin, with a known poor BBB penetration, and temozolomide, conversely specific drug for CNS disorders and able to cross the BBB, to validate the model predictive capability for drug crossing behavior. The proposed sensorized microfluidic device represents a significant advancement in BBB modeling, offering a versatile platform for CNS drug development, disease modeling, and personalized medicine.</span></p>
The ECOLOPES Voxel Model: Multi-domain data integration for ontology-aided generative computational design of ecological building envelopes
<p>The research portrayed in this article is part of the research project ‘ECOlogical building enveLOPES: a game-changing design approach for regenerative ecosystems’ funded by Horizon 2020 Future and Emerging Technologies. The overall research project focuses on developing a multi-domain data-driven computational design framework for the design of ecological building enclosures that addresses humans, plants, animals and microbiota. This article focuses on the development of a key component of the computational workflow in which initial designs are computationally initiated generated and analyzed, namely the ECOLOPES Voxel Model that contains and correlates multi-domain spatialised data for the design process, and its interactions with other components of the ontology-aided generative computational design process for ecological building envelopes.</p> <p>This repository contains all relevant data produced in this paper. Extended technical description is available in the Appendix A to the published paper, containing listing and description of individual voxel data layers. Data were exported from the RDB server (PostgreSQL) in text-based, future-proof format (csv).</p>
Data from: Building on 150 years of knowledge: the freshwater isopod Asellus aquaticus as an integrative eco-evolutionary model system
<p><strong>Introduction</strong></p> <p>This is a literature database with reference information of all papers that use the freshwater isopod <em>Asellus aquaticus</em>; published between the years 1867 and 2020. This database is intended as a starting point for scientists interested in conducting research on and with this organism. The database is currently only available as a single CSV file; future versions may be made available through a more frequently updated SQL database. The database includes specific information about the subject area and content of each paper, as well as bibliographic information. This repository is associated with the paper "Building on 150 years of knowledge: the freshwater isopod<em> Asellus aquaticus</em> as an integrative eco-evolutionary model system", published in Frontiers in Ecology and Evolution.</p> <p><strong>Details on Methods from the electronic supplement:</strong></p> <p>We used the we online search tools of Web of Science (WOS; Clarivate analytics) by searching for the term "asellus aquaticus" in six relevant databases (BIOSIS, CABI, FSTA, Medline, WOS Core Collection and Zoological Records). The database was accessed with a University License (Lund University). We manually downloaded the results and combined them to a single CSV file in Excel (Microsoft). All further processing was done in the statistical programming language R, version 4.0.2 (R Core Team 2020).</p> <p>From the 1238 obtained records we discarded three papers that were published after the year 2020 to work with completed years only. We used the subject areas assigned by WOS to provide an overview of the fields of science in which A. aquaticus has been most studied. Each paper had between one and ten subject areas assigned by WOS (2845 assignments to 1235 papers, meaning 2.3 assignments per paper, on average). To represent these multiple assignments in relation to the actual number of papers per year, we calculated "fractional assignments" by adding up all assignments to a field per year, divided by the total number of assignments in that year, and then multiplied by the number of papers. For example, if there were 12 assignments to "toxicology" in 1993, and 133 assignments in 1993, but only 21 papers published, "toxicology" would get a score of 1.9 papers in 1993 (as calculated by = (12/133)*21). In Figure 1, we represent these "fractional assignments" in the top panel, and the total number of assignments in the lower panel.</p> <p><strong>Caption for figure (1) in publication:</strong></p> <p>FIGURE 1 | Over 150 years of research on and with Asellus aquaticus. The figure summarizes published scientific literature on A. aquaticus. We conducted a quantitative literature survey with the search tools of Web of Science (WOS; Clarivate analytics) by searching for the term "asellus aquaticus" in six databases (i.e., BIOSIS, CABI, FSTA, Medline, WOS Core Collection, and Zoological Records). We found 1235 records, published between 1867 and 2020. (A) The graph shows the number of publications per year within a given subject area, as designated by WOS. (B) The graph shows the total number of publications assigned to a specific subject area. The top 10 fields account for 72.58% of all publications, and are indicated by color coding in A and B (multiple assignments are possible, summing up to 2845 assignments). The inset in B shows a wordcloud with the 100 most used keywords from all A. aquaticus’ publications. Furthermore, we compiled all records with relevant information (e.g., title, keywords, research areas, and abstract) to a single file which is available online. More details can be found in the Supplementary Material.</p>
Model fields supporting the publication "Integrated Assessment of the Risks to Ocean Acidification in the Northern High Latitudes: Regional Comparison of Exposure, Sensitivity and Adaptive Capacity of Pelagic Calcifiers"
<p>These are the model outputs supporting the described manuscript. They include monthly averaged output of aragonite saturation state for each year during the 10-year hindcast. Also included is the particle tracking output, for both the Bering Sea and the Gulf of Alaska, as described in the manuscript.</p>
Novel integrative modeling of molecules and morphology across evolutionary timescales
<p>Evolutionary models account for either population or species-level processes, but usually not both. We introduce a new model, the FBD-MSC, which makes it possible for the first time to integrate both the genealogical and fossilization phenomena, by means of the multispecies coalescent (MSC) and the fossilized birth-death (FBD) processes. Using this model, we reconstruct the phylogeny representing all extant and many fossil Caninae, recovering both the relative and absolute time of speciation events. We quantify known inaccuracy issues with divergence time estimates using the popular strategy of concatenating molecular alignments, and show that the FBD-MSC solves them. Our new integrative method and empirical results advance the paradigm and practice of probabilistic total evidence analyses in evolutionary biology.</p>
Data, code and supplementary material for "A data integration framework for spatial interpolation of temperature observations using climate model data"
<p>Each zipped file contains code and data to reproduce the results in the paper and supplementary material. The Cyprus folder contains also the files to run the model, as well as the associated results. The Morocco folder only contains the results and the code used to manipulate it. </p>
Species detection histories used in Killion et al. (2023): Integrating Spaceborne Estimates of Structural Diversity of Habitat into Wildlife Occupancy Models
<p>Camera trap species detection histories used for occupancy models in "Integrating Spaceborne Estimates of Structural Diversity of Habitat into Wildlife Occupancy Models". </p>
Integration of Renewable Energy Sources into the Water-Energy-Food (WEF) Nexus – Modelling a Demand Side Management Approach and Application to a Microgrid Farm in Morocco Dataset
<p>Here you can find the official data used for the publication "Integration of Renewable Energy Sources into the Water-Energy-Food (WEF) Nexus – Modelling a Demand Side Management Approach and Application to a Microgrid Farm in Morocco"</p> <p>If you want to run the model, please update line 11 in the run.jl file, to select the dataset from the scenario you want to look at. It is also recommended to change the result path, to a directory that corresponts to the current model run in order to find the results files quicker.</p> <p> </p> <p>To create a new plot a file called newPlot.jl can be found, that already take care of most data handling, only lines 136 and 141 need to be changed, in order to read in the result files of the results you want to investigate.</p>
Data from: Evaluating the importance of individual heterogeneity in reproduction to Weddell seal population dynamics using integral projection models
<ol> <li>Identifying and accounting for unobserved individual heterogeneity in vital rates in demographic models is important for estimating population-level vital rates and identifying diverse life-history strategies, but much less is known about how this individual heterogeneity influences population dynamics.</li> <li>We aimed to understand how the distribution of individual heterogeneity in reproductive and survival rates influenced population dynamics using vital rates from a Weddell seal population by altering the distribution of individual heterogeneity in reproduction, which also altered the distribution of individual survival rates through the incorporation of our estimate of the correlation between the two rates and assessing resulting changes in population growth.</li> <li>We constructed an integral projection model (IPM) structured by age and reproductive state using estimates of vital rates for a long-lived mammal that has recently been shown to exhibit large individual heterogeneity in reproduction. Using output from the IPM, we evaluated how population dynamics changed with different underlying distributions of unobserved individual heterogeneity in reproduction.</li> <li>Results indicate that the changes to the underlying distribution of individual heterogeneity in reproduction cause very small changes in the population growth rate and other population metrics. The largest difference in the estimated population growth rate resulting from changes to the underlying distribution of individual heterogeneity was less than 1%.</li> <li>Our work highlights the differing importance of individual heterogeneity at the population level compared to the individual level. Although individual heterogeneity in reproduction may result in large differences in the lifetime fitness of individuals, changing the proportion of above- or below-average breeders in the population results in much smaller differences in annual population growth rate. For a long-lived mammal with stable and high adult-survival that gives birth to a single offspring, individual heterogeneity in reproduction has a limited effect on population dynamics. We posit that the limited effect of individual heterogeneity on population dynamics may be due to canalization of life-history traits.</li> </ol>
Supplementary data of article Integrating Data-Driven and Hydraulic Modelling with Acoustic Sensor Information for Improved Leak Location in Water Distribution Networks
<p>This dataset was generated within the research thesis of Axel Hutomo, under the supervision of Leonardo Alfonso and Ioana Popescu at IHE Delft, and it is published as supplementary data for the article <em>Integrating Data-Driven and Hydraulic Modelling with Acoustic Sensor Information for Improved Leak Location in Water Distribution Networks, </em>currently under review. </p> <p>The Excel sheet provides information about the datasets produced to integrate acoustic sensor data and hydraulic model output data, to be used by the Machine Learning model. The acoustic sensor data were obtained by extracting several features in time and frequency domains from each audio file coming from acoustic sensors, whereas hydraulic model data was obtained by modelling these leaks using a pressure-independent analysis.</p> <p>The Python code shows the building of the ANN for leakage modelling prediction, integrating the two datasets above, for different leak rates.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.