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244 results for “lipopolysaccharide”
Figure 8 in All aspects of the toxic effects of lipopolysaccharide on rat liver and the protective effect of vitamin E and sodium selenite
Figure 8. Control, VE-, SS-, and VE + SS-treated rats, showing PCNA protein expression with immunohistochemical analysis in male rat liver. Single arrow PCNA expression in the group shows multiple apoptotic cells at 200×.
Body size and circulating levels of different molecules from tree swallows (Tachycineta bicolor) exposed to different doses of lipopolysaccharide (LPS)
<p class="CxSpFirst">The purpose of mounting an immune response is to destroy pathogens, but this response comes at a physiological cost, including the generation of oxidative damage. However, many studies on the effects of immune challenges employ a single high dose, meaning that the consequences of more mild immune challenges are poorly resolved. We tested whether the degree of immunological challenge in tree swallows (<i>Tachycineta bicolor</i>) affects oxidative physiology and body mass, and whether these metrics correlate with parasitic nest mite load. We injected 14-day-old nestlings with either 0, 0.01, 0.1, or 1 mg lipopolysaccharide (LPS) per kg body mass, then collected a blood sample 24-h later to quantify multiple physiological metrics, including oxidative damage (i.e., d-ROMs), circulating amounts of triglyceride and glycerol, and levels of the acute phase protein haptoglobin. After fledging, we identified and counted parasitic nest mites (<i>Dermanyssus</i> spp. and <i>Ornithonyssus</i> spp.). We found that only nestlings injected with 1 mg LPS/kg body mass, which is a common dosage in ecoimmunological studies, lost more body mass than individuals from other treatment groups. However, every dose of LPS resulted in a commensurate increase in oxidative damage. Parasitic mite abundance had no effect on oxidative damage across treatments. Amount of oxidative damage correlated with haptoglobin levels, suggesting compensatory mechanisms to limit self-damage during an immune response. We conclude that while only the highest-intensity immune challenges resulted in costs related to body mass, even low-intensity immune challenges result in detectable increases of oxidative damage.</p>
Fig. 1 in Glycoglycerolipids from the leaves of Perilla frutescens (L.) Britton (Labiatae) and their anti-inflammatory activities in lipopolysaccharide-stimulated RAW264.7 cells
Fig. 1. The separation procedures of glycoglycerolipids from Perilla frutescens leaves.
Lipopolysaccharide (LPS) or Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Challenge Study on Healthy Subjects
ClinicalTrials.gov study NCT03306589. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Peripheral Benzodiazepine Receptors (PBR28) Brain PET Imaging With Lipopolysaccharide Challenge for the Study of Microglia Function in Alzheimer's Disease
ClinicalTrials.gov study NCT04057807. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Lipopolysaccharide (LPS) Challenge in Depression
ClinicalTrials.gov study NCT03142919. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Blood Lipopolysaccharide (LPS) Rifaximin Study
ClinicalTrials.gov study NCT02124512. IPD Sharing: NO. Countries: 1. Publications: 0.
Body size and circulating levels of different molecules from tree swallows (Tachycineta bicolor) exposed to different doses of lipopolysaccharide (LPS)
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Transcriptomic Changes in Microdissected CCDs after Three Hours Lipopolysaccharide (LPS) Administration in Rats
GEO Series GSE200928. Rattus norvegicus. 18 samples. Type: Expression profiling by high throughput sequencing.
Effect of stimulation with lipopolysaccharide (LPS) at 0,30, and 60 minutes on gene expression in immortalized mouse macrophages (IMM).
GEO Series GSE248765. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Effect of the USP7 inhibitor HBX41,108 on lipopolysaccharide induced gene expression in mouse bone marrow derived macrophages.
GEO Series GSE149478. Mus musculus. 6 samples. Type: Expression profiling by array.
Lactic acid modifies gene expression and chromatin accessibility of bone marrow-derived macrophages during lipopolysaccharide stimulation (RNA-seq and ATAC-seq)
GEO Series GSE253050. Mus musculus. 22 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Multi-omics analysis of the epigenetic effects of lipopolysaccharide-induced inflammation in Type II Pneumocytes
GEO Series GSE275769. Mus musculus. 36 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
RNA sequencing of human marcrophages treated with lipopolysaccharide (LPS) for 8 hours, with or without BCAT1 inhibitor (ERG240)
GEO Series GSE148701. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Bacterial lipopolysaccharides induce defense responses associated with Programmed cell death in rice cell
GEO Series GSE5906. Oryza sativa; Oryza sativa Japonica Group. 4 samples. Type: Expression profiling by array.
Role of IL-2 inducible T cell kinase (ITK) and Bruton's tyrosine kinase (BTK) in mast cell response to lipopolysaccharide (LPS)
GEO Series GSE64287. Mus musculus. 24 samples. Type: Expression profiling by array.
Interleukin-27-adipose-derived mesenchymal stromal cell-based gene therapy attenuates inflammation in lipopolysaccharide-induced acute respiratory distress syndrome
GEO Series GSE292564. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic response of skeletal muscle to lipopolysaccharide in the gilthead seabream (Sparus aurata)
GEO Series GSE36339. Oncorhynchus mykiss; Sparus aurata. 8 samples. Type: Expression profiling by array.
Activation of a nerve injury transcriptional signature in airway-innervating sensory neurons after lipopolysaccharide induced lung inflammation II
GEO Series GSE141395. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
Droplet-based single-cell RNA-sequencing of mouse and naked mole-rat spleen and circulating immune cells, in natural conditions, following lipopolysaccharide (LPS) challanege, and saline control
GEO Series GSE132642. Heterocephalus glaber; Mus musculus. 63 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
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Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
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