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11,852 results for “liver”
Figure 1 in Anatomical and histological traits of Brycon amazonicus liver cultivated in a semi-intensive system
Figure 1. Graphical representation resulting from the analysis of the weight-length ratio of B. amazonicus cultivated semi-intensively, in four stages of body growth.
Figure 4 in Anatomical and histological traits of Brycon amazonicus liver cultivated in a semi-intensive system
Figure 4. Microscopic image of Brycon amazonicus liver from semi-intensive cultivation. Note the cordonal aspect of the hepatocytes, the absence of lobulation and the presence of blood vessels without pancreatic tissue wrap (arrowhead) and with pancreatic cells surrounding them (arrow). HE, 200X. Bar = 50µm.
Figure 3 in Anatomical and histological traits of Brycon amazonicus liver cultivated in a semi-intensive system
Figure 3. Behavior of semi-intensively cultivated Brycon amazonicus hepatosomatic relationship, according to body growth. Different letters represent significant differences between groups (P <0.05).
Figure 2 in Anatomical and histological traits of Brycon amazonicus liver cultivated in a semi-intensive system
Figure 2. Brycon amazonicus liver after removal of the celomatic cavity and dissection of an individual belonging to the PIII. Note the hepatic lobation and gallbladder (G) located next to the right hepatic lobe, and the red-brown color of de liver.
Whole slide images of mouse liver serial sections - Test registration dataset
<p>15 H&E serial section of mouse liver and small intestine.</p> <p>Sampled prepared in the <a href="https://www.epfl.ch/research/facilities/histology-core-facility/">EPFL histology core facility</a> by Nathalie Müller, Gian-Filippo Mancini, and Agnès Hautier.</p> <p>All slides where imaged with a VS200 Evident slide scanner from the<a href="http://biop.epfl.ch/"> EPFL BIOP imaging facility</a>.</p>
Figure 2 in Potential histopathological and immunological effects of SARS-CoV-2 on the liver
Figure 2. Potential mechanisms of hepatic injury with SARS-CoV-2 infection adapted from Yang et al. (2020).
Figure 6 in Potential Hepatoprotective Effect of Cheatomorpha gracilis extract against High Fat Diet (HFD)-Induced Liver Damage, and its characterization by HPLC
Figure 6. Photomicrographs of hepatocytes in control and experimental treated mice. Liver tissue sections stained with oil red O (×200) (A) and scored (B) by the semi-quantitative percentage of damaged area. (Control) control mice and (AEC) treated with C. gracilis extract (250 mg/kg) alone, showed normal structure. (HFD) high fed diet treated mice, showed a significant increase of lipid content; (AEC + HFD) co-treated with high fed diet and alga extract (250 mg/kg), representative micrograph revealed significantly reduced lipid liver content. Values are expressed as the mean ± SD. **p<0.01; ***p <0.001, indicates a significant difference compared to the control group. ++ p<0.01, indicates a significant difference compared to the HFD alone group.
Figure 3 in Potential Hepatoprotective Effect of Cheatomorpha gracilis extract against High Fat Diet (HFD)-Induced Liver Damage, and its characterization by HPLC
Figure 3. Effect of ACE supplementation on plasma levels of inflammatory proteins. Data are given as mean ± SD for group of eight mice each. Values are statistically presented as follows: HFD and AEC-treated groups vs. control group: *p <0.05; **p<0.01. HFD + AEC group vs. HFD group: +p <0.05; ++p<0.01.
Figure 2 in Potential Hepatoprotective Effect of Cheatomorpha gracilis extract against High Fat Diet (HFD)-Induced Liver Damage, and its characterization by HPLC
Figure 2. Antioxidant activity of different extracts of C. gracilis. Values are mean ± SD of three experimental tests, mg GAE/g DR: mg gallic acid equivalents per g dry residue. Table 4. Effect of AEC on body weight, liver and adipose tissues relative weight of control and treated mice groups.
Figure 5 in Potential Hepatoprotective Effect of Cheatomorpha gracilis extract against High Fat Diet (HFD)-Induced Liver Damage, and its characterization by HPLC
Figure 5. Photographs of liver tissues in control and experimental treated mice. Liver tissue sections stained with hematoxylin and eosin (original magnification × 400). (A), in control mice showing normal histoarchitecture and radiating cell arrangement. (B) In mice treated with aqueous extract of C.gracilis (AEC) (250mg/kg) alone showing the normal liver structure. (C) In High fed diet (HFD) mice, representative photograph shows a significant lipid accumulation. (D) In group co-treated with HFD and AEC, was observed the reduction of fat accumulation.
Figure 1 in Potential Hepatoprotective Effect of Cheatomorpha gracilis extract against High Fat Diet (HFD)-Induced Liver Damage, and its characterization by HPLC
Figure 1. Phenolic compounds of Cheatomorpha gracilis extract by chemical High Performance Liquid Chromatography (HPLC) analysis (gallic acid, Rutin, quercetin, Apegenin, kaempferol and Naringenin).
Figure 4 in Potential Hepatoprotective Effect of Cheatomorpha gracilis extract against High Fat Diet (HFD)-Induced Liver Damage, and its characterization by HPLC
Figure 4. Effects of C.gracilis aqueous extract (AEC) on TBARS and protein carbonyls products (PCO) in HFD-treated mice. TBARS: thiobarbituric acid reactive substance. Data are presented as mean ± SD, n =8. *P≤ 0.05, **P≤ 0.01 compared with the control group. +P ≤0.05, ++P ≤0.01 as compared with HFD- treated mice.
Fig. 1 in Long-term efficacy of two cricket and two liver diets for rearing laboratory fire ant colonies (Hymenoptera: Formicidae: Solenopsis invicta)
Fig. 1. Results of a 1 yr diet study using sugar water and either raw beef liver, raw chicken liver, or crickets to rear colonies of the imported fire ant Solenopsis invicta. A) Mean brood production rating of test colonies with brood: 4 = excel- lent, substantially more brood than workers; 3 = good, brood about equal to workers; 2 = poor, brood substantially less than workers; 1 = bad, only a little brood visible; and 0 = no brood. Colonies were fractionally rated if they ap- peared intermediate. Early in the study, about the end of Mar, we switched from domestic crickets (black squares) to banded crickets (crossed squares) and then back to domestic crickets (black squares) for 6 ant colonies on 6 Jun and then the remaining 7 colonies on 1 Jul. Colonies were eliminated from rating means when the queen died or brood production ceased. B) Percentage of test colonies containing brood plotted against time in months for colonies receiving either beef liver (N =10), chicken liver (N = 10), or crickets (N = 13).
Fig. 1 in Histochemical alterations in liver of Common Carp Cyprinus carpio (Linnaeus, 1785) after glyphosate exposure: Preliminary study
Fig. 1. Sudan III staining intensity in liver of Common Carp after 96 h exposure to glyphosate: А – control, x200; Б – 20 mg/L glyphosate, x400; В – 40 mg/L glyphosate, x400; Г – 72 mg/L glyphosate, x400.
Fig. 1 in Lipid accumulation in Cyprinus carpio (Linnaeus, 1785) liver induced by thiamethoxam
Fig. 1. Intensity of Sudan III staining in Common Carp liver: A – control group, x200; B – 6.6 mg/L insecticide, x400; C – 10 mg/L insecticide, x400; D – 20 mg/L insecticide, x400.
Fig. 4. Relationship between liver weight and host age for elk sampled from 2009 in Fluke abundance versus host age for an invasive trematode (Dicrocoelium dendriticum) of sympatric elk and beef cattle in southeastern Alberta, Canada
Fig. 4. Relationship between liver weight and host age for elk sampled from 2009 to 2011 from Cypress Hills Park, Alberta. Regression lines are maximum likelihood estimates.
Underlying data for "Microscale 3D Liver Bioreactor for In Vitro Hepatotoxicity Testing under Perfusion Conditions"
<p>Underlying data for the paper "Microscale 3D Liver Bioreactor for In Vitro Hepatotoxicity Testing under Perfusion Conditions" published in the journal <em>Bioengineering</em>.</p>
Validation of a standardized MRI method for liver fat and T2* quantification
<p><strong>Dataset description:</strong> These data have been uploaded and shared as part of the manuscript <em>“Validation of a standardized MRI method for liver fat and T2* quantification, Chloe Hutton, Michael L. Gyngell, Matteo Milanesi, Alexandre Bagur, and Michael Brady, Perspectum Diagnostics, Oxford, United Kingdom", which was submitted for publication to PLOS ONE on August 27th 2018.</em></p> <p><strong>Details:</strong> The LMSIDEAL_Results.zip file extracts into 28 MATLAB files (MATLAB R2017b) corresponding to LMS IDEAL PDFF results calculated as described in the above manuscript for 28 sets of publicly-available phantom data available from another repository. The original phantom data can be accessed from (<a href="http://dx.doi.org/10.5281/zenodo.48266)">http://dx.doi.org/10.5281/zenodo.48266)</a> and are described in detail in [Hernando et al., Magn Reson Med. 2017;77:1516-1524. doi: 10.1002/mrm.26228. Epub 2016 Apr 15.].</p> <p>To summarise, the original phantom data were acquired using one phantom at six sites, covering: 3 vendors (GE Healthcare, Siemens and Philips); 2 field strengths (1.5T and 3T); and 2 protocols. One of the six sites had two sets of data (one at the beginning of the phantom study and one at the end), to give (6+1)x2x2=28 sets of data in total. The phantom consisted of 11 vials with oil/water concentrations: 0%, 2.6%, 5.3%, 7.9%, 10.5%, 15.7%, 20.9%, 31.2%, 41.3%, 51.4%, 100%. The data from each system, and for each protocol, involved 6 echoes of complex-valued multi-echo gradient echo MR images.</p> <p>Each of the 28 LMSIDEAL_Results_* MATLAB files contains 3 MAT files:</p> <p>LMSIDEAL_PDFF - contains PDFF maps (sized X x Y x 3 slices)</p> <p>ROI - contains x,y coordinates for each ROI (sized 2 x 11) (circular ROI with diameter approximately = 19.5mm)</p> <p>MEAN - contains mean for each slice and each ROI (sized 3 x 11)</p> <p> </p> <p> </p> <p> </p> <p> </p> <p> </p>
Metabolomics of pediatric fatty liver disease
<p>Fecal and plasma metabolite profiles of non-alcoholic fatty liver disease (NAFLD) in a pediatric cohort</p>
Link to dataset related to article "Sustained activation of detoxification pathways promotes liver carcinogenesis in response to chronic bile acid-mediated damage"
<p>This record contains link to raw data related to article "Sustained activation of detoxification pathways promotes liver carcinogenesis in response to chronic bile acid-mediated damage"</p> <p>Chronic inflammation promotes oncogenic transformation and tumor progression. Many inflammatory agents also generate a toxic microenvironment, implying that adaptive mechanisms must be deployed for cells to survive and undergo transformation in such unfavorable contexts. A paradigmatic case is represented by cancers occurring in pediatric patients with genetic defects of hepatocyte phosphatidylcholine transporters and in the corresponding mouse model (Mdr2-/- mice), in which impaired bile salt emulsification leads to chronic hepatocyte damage and inflammation, eventually resulting in oncogenic transformation. By combining genomics and metabolomics, we found that the transition from inflammation to cancer in Mdr2-/- mice was linked to the sustained transcriptional activation of metabolic detoxification systems and transporters by the Constitutive Androstane Receptor (CAR), a hepatocyte-specific nuclear receptor. Activation of CAR-dependent gene expression programs coincided with reduced content of toxic bile acids in cancer nodules relative to inflamed livers. Treatment of Mdr2-/- mice with a CAR inhibitor blocked cancer progression and caused a partial regression of existing tumors. These results indicate that the acquisition of resistance to endo- or xeno-biotic toxicity is critical for cancers that develop in toxic microenvironments.</p> <p>https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE80777 under the accession GSE80777, which comprises ChIP-seq data (GSE80775) and expression data (GSE80776).</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.