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113
datasets available to search
ShareScore release 0.9.0
Dataset results
113 results for “mash”
Single cell-resolved study of advanced murine MASH reveals a homeostatic pericyte signaling module
GEO Series GSE218295. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Single cell-resolved study of advanced murine MASH reveals a homeostatic pericyte signaling module
GEO Series GSE218300. Mus musculus. 38 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Single cell-resolved study of advanced murine MASH reveals a homeostatic pericyte signaling module
GEO Series GSE218298. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Therapeutic effects of FGF21 mimetic bFKB1 on MASH and atherosclerosis in Ldlr-/-.Leiden mice
GEO Series GSE255321. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Hepatocyte FoxO1 depletion exacerbates hepatic inflammation in MASH
GEO Series GSE293003. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Hetereogenity of liver Treg in the CDAHFD model of MASH
GEO Series GSE314148. Mus musculus. 1 samples. Type: Expression profiling by high throughput sequencing.
Fibrogenic gene signature as early prediction for the efficacy of pharmacological interventions for MASH-associated fibrosis, part2
GEO Series GSE290237. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.
Multiomics analysis of concurrent MASH and atherosclerosis in male and female mice
<p><span>Metabolic dysfunction-associated steatohepatitis (MASH) has reached epidemic proportions with limited therapies available. Surprisingly, the leading cause of death in these patients is atherosclerotic cardiovascular disease. No pharmacological therapy exists to treat MASH and atherosclerosis simultaneously, which is attributed to the lack of translational mouse models, particularly in females. Herein, we have utilized both male and female atheroprone mice, combined with different high-fat diets containing physiologically relevant cholesterol levels, to model concurrent MASH-atherosclerosis. Upon phenotypic characterization using standard histopathology, immunohistochemistry, and biochemical assays on liver, cardiovascular, and plasma samples, we report the first female MASH-atherosclerosis model. Furthermore, we conducted a multi-omics exploration of metabolomic, lipidomic, and transcriptomic profiles altered within these groups, and found metabolic and genomic signatures comparable to the human disease. These models will facilitate future cardiometabolic research to unravel the molecular and metabolic underpinnings at the intersection of MASH and atherosclerosis, which must be pharmacologically targeted.</span></p>
A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH
ClinicalTrials.gov study NCT07221227. IPD Sharing: YES. Countries: 1. Publications: 0.
A Study of UBT251 in Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH)
ClinicalTrials.gov study NCT07145151. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study to Assess the Safety, Pharmacokinetics, and Activity of RO7790121 in Participants With Advanced MASH Liver Fibrosis
ClinicalTrials.gov study NCT06903065. IPD Sharing: NO. Countries: 3. Publications: 0.
A Study to Test How Well BI 770371 is Tolerated by People With Cirrhosis Caused by a Liver Disease Called MASH
ClinicalTrials.gov study NCT06675929. IPD Sharing: YES. Countries: 1. Publications: 0.
Long Term Prediction of MASH-related HCC Risk by Proteomics
ClinicalTrials.gov study NCT07332611. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
ClinicalTrials.gov study NCT06419374. IPD Sharing: Not stated. Countries: 22. Publications: 0.
A Real-world Assessment in Implementation of the MASH Patient Care Pathway in Chinese Population Using the Meinian Health Check-up Database
ClinicalTrials.gov study NCT06741111. IPD Sharing: YES. Countries: 1. Publications: 0.
A Study of IBI362 in Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH)
ClinicalTrials.gov study NCT06937749. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH
ClinicalTrials.gov study NCT07221188. IPD Sharing: YES. Countries: 1. Publications: 0.
Fructose is a Metabolic and Inflammatory Pathogenic Factor in Metabolic Dysfunction-associated Steatohepatitis (MASH)
ClinicalTrials.gov study NCT07013916. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study Evaluating Efruxifermin in Subjects With Non-invasively Diagnosed Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Nonalcoholic Fatty Liver Disea
ClinicalTrials.gov study NCT06161571. IPD Sharing: NO. Countries: 13. Publications: 0.
Efficacy and Safety of CS0159 Combined With Semaglutide in MASH Patients With Obesity and T2DM
ClinicalTrials.gov study NCT06492330. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.