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277
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ShareScore release 0.9.0
Dataset results
277 results for “novel proteins”
Data from: Using viromes to predict novel immune proteins in non-model organisms
Immunity is mostly studied in a few model organisms, leaving the majority of immune systems on the planet unexplored. To characterize the immune systems of non-model organisms alternative approaches are required. Viruses manipulate host cell biology through the expression of proteins that modulate the immune response. We hypothesized that metagenomic sequencing of viral communities would be useful to identify both known and unknown host immune proteins. To test this hypothesis, a mock human virome was generated and compared to the human proteome using tBLASTn, resulting in 36 proteins known to be involved in immunity. This same pipeline was then applied to reef-building coral, a non-model organism that currently lacks traditional molecular tools like transgenic animals, gene-editing capabilities, and in vitro cell cultures. Viromes isolated from corals and compared with the predicted coral proteome resulted in 2503 coral proteins, including many proteins involved with pathogen sensing and apoptosis. There were also 159 coral proteins predicted to be involved with coral immunity but currently lacking any functional annotation. The pipeline described here provides a novel method to rapidly predict host immune components that can be applied to virtually any system with the potential to discover novel immune proteins.
Common protein interactions explain variant oncofusion function and predict a novel oncofusion in rhabdomyosarcoma
<p>Original Westerns from publications</p>
Exploring the venom gland transcriptome of Bothrops asper and Bothrops jararaca: de novo assembly and analysis of novel toxic proteins
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HotProtein: A Novel Framework for Protein Thermostability Prediction and Editing
<p>Data set provided with the paper "HotProtein: A Novel Framework for Protein Thermostability Prediction and Editing". Please solely cite the <a href="https://openreview.net/forum?id=YDJRFWBMNby&noteId=vl18g7_lVT">paper</a> if you use the data.</p> <p>Data was downloaded from the provided <a href="https://github.com/VITA-Group/HotProtein">GitHub</a> links 2023/07/11:</p> <p>Datasets</p> <ul> <li>HP-S2C2</li> <li>HP-S2C5</li> <li>HP-S:</li> </ul>
PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) Radioligand
ClinicalTrials.gov study NCT03958630. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Dose-finding Study of Novel Erythropoiesis Stimulating Protein (NESP) for the Treatment of Anaemia in Subjects With Solid Tumours Receiving Multicycle Chemotherapy
ClinicalTrials.gov study NCT00540384. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Data from: The basic keratin 10-binding domain of the virulence-associated pneumococcal serine-rich protein PsrP adopts a novel MSCRAMM fold
Open the record for dataset details and reuse information.
Data from: Using viromes to predict novel immune proteins in non-model organisms
Open the record for dataset details and reuse information.
Cell type specific profiling of alternative translation identifies novel protein isoforms in the mouse brain
GEO Series GSE115483. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing; Other.
A Novel Human Protein-Coding Locus Identified Using a Targeted RNA Enrichment Technique
GEO Series GSE275424. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
Epitope Mapping of potential novel immunogenic proteins of Klebsiella pneumoniae MGH 78578
GEO Series GSE52537. Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819; Klebsiella pneumoniae. 20 samples. Type: Protein profiling by protein array.
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy NA-seq (time course) May 15, 2018 approved TSV
GEO Series GSE99183. Homo sapiens. 49 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Evaluation of novel computational methods that identify RNA-binding protein footprints from structural data
GEO Series GSE262542. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Novel roles of C. elegans heterochromatin protein HP1 and linker histone HIS-24 in the regulation of innate immune gene expression and stress Response
GEO Series GSE25714. Caenorhabditis elegans. 10 samples. Type: Expression profiling by array.
The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway
GEO Series GSE280944. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
The antiviral nuclear body protein SP140 represses Ifnb1 transcript stabilization by the novel regulator RESIST [RNA-seq]
GEO Series GSE269761. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
A novel nuclear protein complex controlling the expression of developmentally regulated genes in Toxoplasma gondii [RNA-seq]
GEO Series GSE277550. Toxoplasma gondii. 18 samples. Type: Expression profiling by high throughput sequencing.
A novel role of Tet1/2 proteins in cell cycle progression of trophoblast stem cells
GEO Series GSE109545. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
The major urinary protein gene cluster knockout mouse as a novel model for translational metabolism research
GEO Series GSE188158. Mus musculus. 47 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
Identification of a novel, tunable interface in the S.pombe HP1 protein, Swi6, that underpins epigenetic inheritance.
GEO Series GSE248428. Schizosaccharomyces pombe. 28 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.