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165 results for “nucleoside”
A Comparison of Three Treatments for Advanced HIV Disease in Patients Who Have Received Nucleoside Therapy in the Past
ClinicalTrials.gov study NCT00001029. IPD Sharing: Not stated. Countries: 3. Publications: 2.
The Norwegian Nucleoside Analogue Stop Study
ClinicalTrials.gov study NCT03681132. IPD Sharing: Not stated. Countries: 4. Publications: 2.
Comparing a Nucleoside-Analogue-Sparing Regimen and a Protease-Inhibitor-Sparing Regimen in HIV Infected Patients
ClinicalTrials.gov study NCT00135460. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Prospective Clinical Trial in Chronic Hepatitis B Patients NAs (Nucleotides or Nucleosides) Experienced (Anchor Study)
ClinicalTrials.gov study NCT02327416. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Prevention of Perinatal Transmission of HIV-1 Without Nucleoside Reverse Transcriptase Inhibitors
ClinicalTrials.gov study NCT02738502. IPD Sharing: UNDECIDED. Countries: 1. Publications: 7.
Second-line Therapy Antiretroviral in Patients Who Failed Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI) - Based Regimens
ClinicalTrials.gov study NCT00627055. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Nucleoside Therapy in Patients With Telomere Biology Disorders
ClinicalTrials.gov study NCT06817590. IPD Sharing: NO. Countries: 1. Publications: 1.
SNAP: Switching Nucleoside Analogues Protocol - Lipoatrophy and Mitochondrial Function
ClinicalTrials.gov study NCT00225082. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Figure 8 from: Bulbul MZH, Chowdhury TS, Misbah MMH, Ferdous J, Dey S, Hasan I, Fujii Y, Ozeki Y, Kawsar SMA (2021) Synthesis of new series of pyrimidine nucleoside derivatives bearing the acyl moieties as potential antimicrobial agents. Pharmacia 68(1): 23-34. https://doi.org/10.3897/pharmacia.68.e56543
Figure 8 Structures of compounds 7 (octanoyl derivative), 9 (myristoyl derivative), and 14 (dichloroacetyl derivative).
Scheme 1 from: Bulbul MZH, Chowdhury TS, Misbah MMH, Ferdous J, Dey S, Hasan I, Fujii Y, Ozeki Y, Kawsar SMA (2021) Synthesis of new series of pyrimidine nucleoside derivatives bearing the acyl moieties as potential antimicrobial agents. Pharmacia 68(1): 23-34. https://doi.org/10.3897/pharmacia.68.e56543
Scheme 1 Reagents and conditions: (a) dry Py, (C6H5)3COCl, –5 °C, 6 h, (70%; Rf = 0.52); (b) dry Py, various acyl halides (3–14), 0 °C to rt, DMAP, 6 h.
Figure 5 from: Bulbul MZH, Chowdhury TS, Misbah MMH, Ferdous J, Dey S, Hasan I, Fujii Y, Ozeki Y, Kawsar SMA (2021) Synthesis of new series of pyrimidine nucleoside derivatives bearing the acyl moieties as potential antimicrobial agents. Pharmacia 68(1): 23-34. https://doi.org/10.3897/pharmacia.68.e56543
Figure 5 Percentage zone of mycelial growth inhibition for compounds 3 and 11 against A. niger (A and B, respectively). DMSO represents the negative control, whereas nystatin is the positive control.
Figure 2 from: Bulbul MZH, Chowdhury TS, Misbah MMH, Ferdous J, Dey S, Hasan I, Fujii Y, Ozeki Y, Kawsar SMA (2021) Synthesis of new series of pyrimidine nucleoside derivatives bearing the acyl moieties as potential antimicrobial agents. Pharmacia 68(1): 23-34. https://doi.org/10.3897/pharmacia.68.e56543
Figure 2 Percentage of inhibition observed for A) B. subtilis by compounds 7, 9, and 8; B) E. coli by compounds 2, 4, and 9; C) S. abony by compounds 7, 9, and 14; and D) S. aureus by compounds 7, 9, and 14. DMSO was the negative control, whereas azithromycin represented the positive control.
Figure 7 from: Bulbul MZH, Chowdhury TS, Misbah MMH, Ferdous J, Dey S, Hasan I, Fujii Y, Ozeki Y, Kawsar SMA (2021) Synthesis of new series of pyrimidine nucleoside derivatives bearing the acyl moieties as potential antimicrobial agents. Pharmacia 68(1): 23-34. https://doi.org/10.3897/pharmacia.68.e56543
Figure 7 Percentage growth inhibition observed for various concentrations of compound 9. Right figure 96-well flat-bottom experiment.
Orbitrap LC-MS/MS data for phage nucleosides
<p>These are files containing LC-MS/MS data for phage T4 and phage SPO1 nucleosides. Phage SPO1 data are in files prefixed ORB59709, and T4 data are in files prefixed with ORB59710. The .RAW files are Thermo .raw files obtained after tandem mass spectrometry, and were converted to .mgf format using MSConvert 3.0.22031 (a component of the Proteowizard open source mass spectrometry bioinformatics software package) under generic default presets for .mgf file extraction.</p> <p>Also included are our mass and charge lists for known nucleosides, known charged adducts, and known neutral adducts.</p> <p>File list: </p> <p>ORB59709.RAW = Raw SPO1 data<br> ORB59709.mgf = Processed SPO1 data<br> ORB59710.RAW = Raw T4 data<br> ORB59710.mgf = Processed T4 data</p> <p>Mass_lists_Nucleosides.csv = Masses and charges of known nucleosides<br> Mass_lists_Charged_adducts.csv = Masses and charges of common charged adducts<br> Mass_lists_Neutral_adducts.csv = Masses of common neutral adducts</p> <p> </p>
Clinical Trial to Evaluate the Efficacy, Pharmacokinetics (PK) Interactions and Safety of Dolutegravir Plus 2 Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in HIV-1-Infected Solid Organ Transpla
ClinicalTrials.gov study NCT03360682. IPD Sharing: NO. Countries: 1. Publications: 0.
Study of Lopinavir/Ritonavir Tablets Versus Soft Gel Capsules and Once Daily Versus Twice Daily Administration, When Coadministered With Nucleoside Reverse Transcriptase Inhibitors in Antiretroviral N
ClinicalTrials.gov study NCT00262522. IPD Sharing: Not stated. Countries: 19. Publications: 0.
Study to Evaluate Switching From Regimens Consisting of a Ritonavir-boosted Protease Inhibitor (PI) and Two Nucleoside Reverse Transcriptase Inhibitors (NRTIs) to a Fixed-dose Tablet Containing Emtric
ClinicalTrials.gov study NCT01252940. IPD Sharing: Not stated. Countries: 10. Publications: 0.
Observational Study of Fat Loss in HIV Infected Adults Taking Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
ClinicalTrials.gov study NCT00119405. IPD Sharing: Not stated. Countries: 1. Publications: 0.
TMC125-TiDP2-C238: An Exploratory Pharmacokinetics, Safety and Anti-HIV Activity Study of Etravirine (ETR) When Given With Boosted Atazanavir (ATV/Rtv) at Two Different Doses and 1 Nucleoside Reverse
ClinicalTrials.gov study NCT00896051. IPD Sharing: Not stated. Countries: 5. Publications: 0.
Atazanavir (BMS-232632) in Combination With Ritonavir or Saquinavir, and Lopinavir/Ritonavir, Each With Tenofovir and a Nucleoside in Subjects With HIV
ClinicalTrials.gov study NCT00035932. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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