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90 results for “schistosomiasis”
Effect of Schistosomiasis Mansoni on HIV Susceptibility and Female Genital Immunology
ClinicalTrials.gov study NCT02878564. IPD Sharing: NO. Countries: 1. Publications: 4.
Childhood Schistosomiasis: a Novel Strategy Extending the Benefits/Reach of Antihelminthic Treatment
ClinicalTrials.gov study NCT02495909. IPD Sharing: NO. Countries: 1. Publications: 3.
Schistosomiasis Diagnosis Using a CAA Antigen Test
ClinicalTrials.gov study NCT03779347. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Activity of Mefloquine Against Urinary Schistosomiasis
ClinicalTrials.gov study NCT01132248. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Study to Evaluate the Safety of the Vaccine Prepared sm14 Against Schistosomiasis
ClinicalTrials.gov study NCT01154049. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Single-sex Female Controlled Human Schistosomiasis Mansoni Infection
ClinicalTrials.gov study NCT04269915. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Comparing Praziquantel Versus Artesunate + Sulfamethoxypyrazine/Pyrimethamine for Treating Schistosomiasis
ClinicalTrials.gov study NCT00510159. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Epidemiological interactions between urogenital and intestinal human schistosomiasis in the context of praziquantel treatment across three West African countries
Open the record for dataset details and reuse information.
Data from: Evolutionary epidemiology of schistosomiasis: linking parasite genetics with disease phenotype in humans
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Fig. 2 in Considering ivermectin for treatment of schistosomiasis
Fig. 2 Liver histology of schistosome-infected mice treated with ivermectin or artemisone on days 41 and 42 postinfection
Schistosomiasis in immigrants, refugees and travellers in an Italian referral centre for tropical diseases
<p>Schistosomiasis is one of the most important neglected tropical diseases. If unrecognised and untreated, the chronic infection can lead to irreversible complications.</p> <p>METHODS:</p> <p>Retrospective observational study aimed at describing clinical history, laboratory findings and imaging presentation of imported schistosomiasis diagnosed at the Centre for Tropical Diseases, Sacro Cuore Don Calabria Hospital of Negrar, Verona, Italy from 2010 to 2014. The aim of our study was to assess differences in demographic characteristics, clinical presentation, laboratory data and ultrasound findings between immigrants/visiting friends and relatives (VFR) from endemic countries (endemic group) and expatriates/travellers (non-endemic group).</p> <p>RESULTS:</p> <p>A total of 272 patients were retrieved: 234 in the endemic and 38 in the non-endemic group. Most of the patients acquired schistosomiasis in Africa (97.4%). Symptoms were reported by 52.9% of the patients; abdominal pain (36%), macroscopic hematuria (11.3%), and genito-urinary symptoms (7.4%) being the most frequently reported. Increased IgE and blood eosinophilia were observed in 169 (63.8%) and 130 (47.8%) patients, respectively. The proportion of positive serology was 250/272 (91.9%).The Circulating Cathodic Antigen CCA for Schistosoma mansoni was positive in 14/61 individuals (23%). At microscopy, infected subjects were 103/272 (37.9%). The species of Schistosoma found were S. haematobium (47.6%), S. mansoni (46.6%) or both (5.8%). Schistosomiasis was classified as confirmed in 103 (37.9%), probable in 165 (60.6%) and suspected in 4 (1.5%) cases using clinical presentation, laboratory data and ultrasound findings. The infection was further classified based on organ involvement: intestinal (17.9%), hepatosplenic (5.1%), urogenital (48.9%), and indeterminate (43.8%). The comparative analysis of endemic and non-endemic patients highlighted differences in sex and age. Endemic patients had more frequent ova identification (41.9% vs. 13.2%, P < 0.001) and increased IgE (70% vs. 26.3%, P < 0.001) when compared with non-endemic. Multivariate analyses showed that younger age, abnormal ultrasound findings and blood eosinophilia were significantly associated with positive microscopy (OR = 0.94, OR = 2.12, OR = 1.98, respectively).</p> <p>CONCLUSIONS:</p> <p>Symptoms, eosinophilia and abnormal ultrasound findings were present in about half of patients, without differences between groups. Many patients had positive serology but negative microscopy, indicating that schistosomiasis might be misdiagnosed. A combination of diagnostic tools may facilitate the diagnosis.</p>
An Open Label Dose Finding Safety and Efficacy in Children and Infants Infected With Schistosomiasis (S.Mansoni)
ClinicalTrials.gov study NCT02806232. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effect of Concomitant Mansonella Perstans Microfilaremia on Immune Responses Following Single Dose Praziquantel in People With Schistosomiasis
ClinicalTrials.gov study NCT02734186. IPD Sharing: Not stated. Countries: 0. Publications: 3.
Adoption of L-PZQ for Schistosomiasis by Endemic Counties - Social Science Research Study
ClinicalTrials.gov study NCT05350462. IPD Sharing: NO. Countries: 3. Publications: 0.
Sex-specific Schistosomiasis induced metabolic modulation of the myeloid lineage
GEO Series GSE144447. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Gene expression changes in murine ileum during inflammation: Controls vs. intestinal schistosomiasis and TNBS-ileitis.
GEO Series GSE31265. Mus musculus. 11 samples. Type: Expression profiling by array.
Maternal Schistosomiasis CD45+
GEO Series GSE162075. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
Ex vivo mouse model for hepatic schistosomiasis
GEO Series GSE64071. Mus musculus. 32 samples. Type: Expression profiling by array.
Temporal Expression of Chemokines Dictates the Hepatic Inflammatory Infiltrate in a Murine Model of Schistosomiasis.
GEO Series GSE14367. Schistosoma japonicum; Mus musculus. 10 samples. Type: Expression profiling by array.
Filling Key Research Gaps With Clinical Implications in Mansonellosis and Schistosomiasis: a Network Approach
ClinicalTrials.gov study NCT06311344. IPD Sharing: Not stated. Countries: 1. Publications: 0.
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Allen Brain Atlas
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.