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728 results for “urine”
A Clinical Study in Patients With Overactive Bladder With Leakage of Urine, to Find Out if the Medicine, Fesoterodine, Works in Those Patients Who Did Not Have Enough Response to the Medicine, Toltero
ClinicalTrials.gov study NCT01302054. IPD Sharing: Not stated. Countries: 15. Publications: 3.
Diuretic Treatment in Acute Heart Failure With Volume Overload Guided by Serial Spot Urine Sodium Assessment
ClinicalTrials.gov study NCT05411991. IPD Sharing: YES. Countries: 1. Publications: 1.
Bisphenol A in Saliva and Urine Related to Placement of Dental Composites
ClinicalTrials.gov study NCT02575118. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Point-of-care Urine Monitoring of Adherence: Testing a Real-Time Urine Assay of Tenofovir in PrEP
ClinicalTrials.gov study NCT03935464. IPD Sharing: YES. Countries: 1. Publications: 6.
Restricted Reporting for Positive Urine Cultures
ClinicalTrials.gov study NCT02797613. IPD Sharing: NO. Countries: 1. Publications: 1.
UroCAD Assay Combined With Computed Tomography Urography and Urine Cytology for UTUC Diagnosis.
ClinicalTrials.gov study NCT05043662. IPD Sharing: NO. Countries: 1. Publications: 3.
Variation in Urine Electrolytes, pH and Specific Gravity Throughout the Day
ClinicalTrials.gov study NCT03645785. IPD Sharing: NO. Countries: 1. Publications: 21.
Antibiotic Selection Using Next Generation Sequencing vs Urine Culture
ClinicalTrials.gov study NCT04404855. IPD Sharing: YES. Countries: 1. Publications: 1.
Bladder Scan of Residual Urine With New Catheter
ClinicalTrials.gov study NCT01048541. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Effect of Urinary Alkalinization on Urine Uric Acid Precipitation and Crystallization in Adults With Type 1 Diabetes
ClinicalTrials.gov study NCT02502071. IPD Sharing: Not stated. Countries: 1. Publications: 12.
Urine Tenofovir Point-of-care Test to Identify Patients in Need of ART Adherence Support (UTRA Study)
ClinicalTrials.gov study NCT05333679. IPD Sharing: YES. Countries: 1. Publications: 57.
Urine washing and urinary odor profiles in relation to dominance rank status in wild male capuchin monkeys (Cebus imitator)
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Data from: Preference for mammalian urine is higher in the canopy than on the ground in a tropical rainforest ant community in Yunnan, China
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Immunoassay and proteomics dataset: Identification and validation of urine CXCL-9 as a biomarker for diagnosis of acute interstitial nephritis
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Demographic information and phthalate metabolite concentrations (µg/L) detected in bottlenose dolphins (Tursiops truncatus) urine sampled from Barataria Bay, LA during 2011-2023 and Sarasota Bay, FL during 2010-2019, 2022-2024
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Characterisation and relative abundance of bacteria present in the urine of a frog
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Sanitised human urine (Oga) as a fertilizer auto-innovation from women farmers in Niger
<p>This is a data set of the of three years of field trial with sanitised human urine that was submitted to ASDE Journal for publication consideration purpose.</p>
Data from: Untargeted metabolomic profiling of urine from healthy dogs and dogs with chronic hepatic disease
Chronic hepatic disease can present a diagnostic challenge with different etiologies being associated with similar clinical and laboratory findings. The histopathological assessment of a liver biopsy specimen is usually required in order to make a definitive diagnosis and the availability of non-invasive prognostic biomarkers is limited. The emerging science of metabolomics is used to detect changes in endogenous low molecular weight metabolites in biological samples and offers the possibility of identifying noninvasive markers of disease. The objective of this study was to investigate differences in the urine metabolome between healthy dogs, dogs with chronic hepatitis, dogs with hepatocellular carcinoma, and dogs with a congenital portosystemic shunt. Stored urine samples from 10 healthy dogs, 10 dogs with chronic hepatitis, 6 dogs with hepatocellular carcinoma, and 5 dogs with a congenital portosystemic shunt were analyzed. The urine metabolome was analyzed by gas chromatography – quadrupole time of flight mass spectrometry and 220 known metabolites were identified. Principal component analysis and heat dendrogram plots of the metabolomics data showed clustering between groups. Random forest analysis showed differences in the abundance of various metabolites including putrescine, gluconic acid, sorbitol, and valine. Based on univariate statistics, 37 metabolites were significantly different between groups. In, conclusion, the urine metabolome varies between healthy dogs, dogs with chronic hepatitis, dogs with hepatocellular carcinoma, and dogs with a congenital portosystemic shunt. Further targeted assessment of these metabolites is needed to assess their diagnostic utility.
Raw data for Urine DNA (uDNA) as a non-lethal method for endoparasite biomonitoring: development and validation
<p>Changes in environmental conditions alter host-parasite interactions, raising the need for effective epidemiological surveillance. Developing operational, accurate, and cost-effective methods to assess individual infection status and potential for pathogen spread is a prerequisite to anticipate future disease outbreaks in wild populations. For endoparasites, effective detection of infections usually relies on host-lethal approaches, which are barely compatible with wildlife conservation objectives. Here, we used the brown trout (<i>Salmo trutta</i>) - <i>Tetracapsuloides bryosalmonae</i> host-parasite system to develop a non-lethal method for endoparasite infection detection, hereafter called "uDNA" for urine DNA. The uDNA diagnostic test is based on the amplification of endoparasite DNA from host urine. We sampled wild fish (N = 111) from eight sites, let them excrete in individual buckets filled with mineral water and performed parasite DNA amplification from water filtration. We compared the results of the uDNA diagnostic test for host infection status and parasite load to those from kidney samples (the current standard method). uDNA was sensitive in determining host infection status (even for infected hosts showing no sign of the disease), since up to 90% of fish individuals were correctly assigned to their infection status. The quantity of uDNA detected from the hosts depended on the sampling sites, suggesting a spatial variation in the parasite spread. uDNA was positively, but weakly correlated with parasite load in the kidney. This correlation depended on the severity of macroscopic lesions caused by the disease, and was negative in fish with severely damaged kidney, likely due to impaired urine excretion. The uDNA approach provides novel avenues to non-lethally infer infection parameters from wildlife populations at large spatial scales. By targeting parasite transmission stage, uDNA is also valuable to get insights on the parasite fitness and the ecological and evolutionary dynamics of this host-parasite interaction.</p>
Urine uromodulin as a biomarker of kidney tubulointerstitial fibrosis
Background and objectives <p> </p> <p class="MsoNormal">Uromodulin, produced exclusively in the kidney's thick ascending limb, is a biomarker of kidney tubular health. However, the relationship between urine uromodulin and histological changes in kidney tubulointerstitium has not been characterized. In this study, we test the association of urine uromodulin with kidney histological findings in humans and mice. </p> Design, setting, participants, and measurements <p> </p> <p class="MsoNormal">We investigated the independent association of urine uromodulin measured at the time of kidney biopsy with histological features in 364 participants at two academic medical centers from 2015-2018 using multivariable linear regression models. This relationship was further examined by comparison of uromodulin staining in murine models of kidney fibrosis and repair. </p> <p> </p> Results <p> </p> <p class="MsoNormal">We found urine uromodulin to be correlated with serum creatinine (rho = -0.43, P<0.001), bicarbonate (0.20, P<0.001) and hemoglobin (0.11, P=0.03) at the time of biopsy, but not with urine albumin (-0.07, P=0.34). Multivariable models controlling for pre-biopsy glomerular filtration rate, serum creatinine at biopsy, and urine albumin showed higher uromodulin to be associated with lower severity of interstitial fibrosis/tubular atrophy (IF/TA) and glomerulosclerosis [IF/TA -3.5 (-5.7, -1.2)% and glomerulosclerosis -3.3 (-5.9, -0.6)% per 2-fold difference in uromodulin]. However, when both IF/TA and glomerulosclerosis were included in multivariable analysis, only IF/TA was independently associated with uromodulin [IF/TA -2.5 (-4.6, -0.4)% and glomerulosclerosis -0.9 (-3.4, 1.5)% per 2-fold difference in uromodulin]. In mouse kidneys, uromodulin staining was found to be lower in the fibrotic model than in normal or repaired models. </p> Conclusions <p><span>Higher urine uromodulin is independently associated with lower tubulointerstitial fibrosis in both human kidney biopsies and a mouse model of fibrosis. </span></p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.