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154 results for “vitamin B12”
Acceptability of Folic Acid and Vitamin B12 Fortified Meals
ClinicalTrials.gov study NCT06094049. IPD Sharing: NO. Countries: 1. Publications: 2.
A Study of Vitamin B12 Status in Children With Infantile Tremor Syndrome and Pre Infantile Tremor Syndrome
ClinicalTrials.gov study NCT02762682. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Impact of Vitamin B12 Supplementation With Iron and Folic Acid on Adolescent Girls
ClinicalTrials.gov study NCT01490944. IPD Sharing: Not stated. Countries: 1. Publications: 15.
Study on the Improvement of Microcirculation in Patients With Sepsis by Vitamin B6, Vitamin B12 and Vitamin C
ClinicalTrials.gov study NCT06749756. IPD Sharing: NO. Countries: 1. Publications: 7.
Effect of Toothpaste Fortified With Cyanocobalamin on Vitamin B12 Status
ClinicalTrials.gov study NCT02679833. IPD Sharing: NO. Countries: 1. Publications: 2.
Dietary Intake of Folic Acid and Vitamin B12 Among Teenage Girls - Validation of Food Frequency Questionnaire
ClinicalTrials.gov study NCT06094023. IPD Sharing: NO. Countries: 1. Publications: 2.
Vitamin B12 Supplementation During Pregnancy
ClinicalTrials.gov study NCT01795131. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Bread Trial: Effects of Bread Fortified With Folic Acid and Vitamin B12
ClinicalTrials.gov study NCT00353353. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Assessing the Efficacy of Different Carrier Systems in Oral Vitamin B12 Supplementation
ClinicalTrials.gov study NCT06376591. IPD Sharing: NO. Countries: 1. Publications: 1.
How Many Patients Are in Need of Vitamin B12 Injections?
ClinicalTrials.gov study NCT00326833. IPD Sharing: Not stated. Countries: 1. Publications: 1.
To Evaluate the Effect of Reveratrol,Folic Acid, Vitamin D, Vitamin B12 and B6 in Male Infertility
ClinicalTrials.gov study NCT03864198. IPD Sharing: NO. Countries: 1. Publications: 14.
Vitamin B6, B12, Folic Acid and Exercise in Parkinson's Disease
ClinicalTrials.gov study NCT01238926. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Data from: Decreased brain levels of vitamin B12 in aging, autism and schizophrenia
Many studies indicate a crucial role for the vitamin B12 and folate-dependent enzyme methionine synthase (MS) in brain development and function, but vitamin B12 status in the brain across the lifespan has not been previously investigated. Vitamin B12 (cobalamin, Cbl) exists in multiple forms, including methylcobalamin (MeCbl) and adenosylcobalamin (AdoCbl), serving as cofactors for MS and methylmalonylCoA mutase, respectively. We measured levels of five Cbl species in postmortem human frontal cortex of 43 control subjects, from 19 weeks of fetal development through 80 years of age, and 12 autistic and 9 schizophrenic subjects. Total Cbl was significantly lower in older control subjects (> 60 yrs of age), primarily reflecting a >10-fold age-dependent decline in the level of MeCbl. Levels of inactive cyanocobalamin (CNCbl) were remarkably higher in fetal brain samples. In both autistic and schizophrenic subjects MeCbl and AdoCbl levels were more than 3-fold lower than age-matched controls. In autistic subjects lower MeCbl was associated with decreased MS activity and elevated levels of its substrate homocysteine (HCY). Low levels of the antioxidant glutathione (GSH) have been linked to both autism and schizophrenia, and both total Cbl and MeCbl levels were decreased in glutamate-cysteine ligase modulatory subunit knockout (GCLM-KO) mice, which exhibit low GSH levels. Thus our findings reveal a previously unrecognized decrease in brain vitamin B12 status across the lifespan that may reflect an adaptation to increasing antioxidant demand, while accelerated deficits due to GSH deficiency may contribute to neurodevelopmental and neuropsychiatric disorders.
Solution, Crystal and in Silico Structures of the Organometallic Vitamin B12-Derivative Acetylcobalamin and of its Novel Rhodium- Analogue Acetylrhodibalamin
<p>Cartesian coordinate files of all calculated structures discussed in the publication.</p>
TRIM: Danish Form and Dose Study on Vitamin B12
ClinicalTrials.gov study NCT02832726. IPD Sharing: NO. Countries: 0. Publications: 1.
Study of Pralatrexate With Vitamin B12 and Folic Acid Supplementation for Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC)
ClinicalTrials.gov study NCT01183065. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effect of a Dietary Supplement Containing EGCG, Folic Acid, Vitamin B12 and Hyaluronic Acid in Supporting Male Genital Balance in Subjects Exposed to HPV Risk
ClinicalTrials.gov study NCT07320183. IPD Sharing: NO. Countries: 0. Publications: 38.
Effect of an Antioxidants Mix on Cognitive Performance and Well Being: The Bacopa, Licopene, Astaxantina, Vitamin B12
ClinicalTrials.gov study NCT03825042. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Vitamin B12, Folic Acid and Vitamin D Status in Women of Reproductive Age
ClinicalTrials.gov study NCT07100795. IPD Sharing: NO. Countries: 1. Publications: 0.
Metformin Usage Index and Vitamin B12 Status in Egyptian Type 2 Diabetic Patients
ClinicalTrials.gov study NCT04882332. IPD Sharing: NO. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.