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1,274 results for “Disease Model”

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geo24/100

Transcriptome profiling in knock-in mouse models of Huntington's disease [Liver_mRNA]

GEO Series GSE65772. Mus musculus. 167 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2016View details →
geo24/100

Developing a novel human adult kidney organoid model to recapitulate injury-associated regeneration and polycystic kidney disease [scRNA-Seq]

GEO Series GSE241972. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2023View details →
geo24/100

Whole transcriptome analysis of UUO mouse model of renal fibrosis reveals new molecular players in kidney diseases

GEO Series GSE79443. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2016View details →
geo24/100

Eicosatetraynoic Acid Regulates Pro-Fibrotic Pathways in an Induced Pluripotent Stem Cell Derived Macrophage:Human Intestinal Organoid Model of Crohn’s Disease II

GEO Series GSE266974. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2025View details →
geo24/100

Genomic profiling of striatum from a mouse model of Huntington's disease (Q140) crossed with Msh3 knockout mice [ATACSeq]

GEO Series GSE235279. Mus musculus. 24 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenFeb 2025View details →
geo24/100

Mature Polarized Hepatocyte Organoids Derived from Human Embryonic Stem Cells for Modeling the Pathogenesis and Progression of Metabolic Dysfunction-Associated Steatotic Liver Disease and Therapeutic

GEO Series GSE303090. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2026View details →
geo24/100

Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model [EmRibo-seq]

GEO Series GSE103429. Mus musculus. 14 samples. Type: Other.

openGEO-OpenOct 2017View details →
geo24/100

MITF-low melanoma subtype models in zebrafish reveal transcriptional sub-clusters and MITF-independent residual disease

GEO Series GSE136900. Danio rerio. 332 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2019View details →
geo24/100

A Mouse Model for Metabolic Dysfunction-associated Steatotic Liver Disease and Hepatocellular Carcinoma [RNA-seq]

GEO Series GSE246221. Mus musculus; Homo sapiens. 148 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJun 2024View details →
geo24/100

Lung miRNA profiling in mouse model of allergic airways disease

GEO Series GSE72793. Mus musculus. 16 samples. Type: Non-coding RNA profiling by array.

openGEO-OpenDec 2015View details →
geo24/100

iPSCs from patients with NBS as a model uncovering disease mechanisms and a screening platform for anti-oxidants modifying genomic stability [fibroblasts]

GEO Series GSE94706. Homo sapiens. 8 samples. Type: Expression profiling by array.

openGEO-OpenAug 2017View details →
geo24/100

RNA-sequencing uncovers transcriptomes of human diseased, healthy, and disease-modeled retinal pigment epithelial cells.

GEO Series GSE126633. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2019View details →
geo24/100

Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer's Disease model

GEO Series GSE150358. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2020View details →
geo24/100

Alzheimer’s disease-linked risk alleles elevate microglial cGAS-associated senescence and neurodegeneration in a tauopathy model [bulk_RNAseq]

GEO Series GSE254103. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2024View details →
geo24/100

Expression data from GNMT and MAT1A knockout models that develop all the stages of non-alcoholic fatty liver disease including hepatocellular carcinoma [GNMT_MAT1A_3&8_months]

GEO Series GSE63027. Mus musculus. 39 samples. Type: Expression profiling by array.

openGEO-OpenNov 2014View details →
geo24/100

Identification of mechanistic chronic kidney disease biomarkers by comprehensive bulk RNA-seq transcriptomics and SWATH proteomics of the rat sub-total nephrectomy model of kidney fibrosis [RNA-Seq_2]

GEO Series GSE253008. Rattus norvegicus. 6 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2025View details →
geo24/100

Hippocampal gene expression in the GFAP-R237H rat model of Alexander disease at early and late stages of disease

GEO Series GSE278645. Rattus norvegicus. 32 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenApr 2025View details →
geo24/100

Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids

GEO Series GSE184928. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2022View details →
geo24/100

Identification and functional impact of genomic copy number variants in zebrafish, an important human disease model (Zebrafish Strain CNVs) (expression array)

GEO Series GSE28239. Danio rerio. 7 samples. Type: Expression profiling by array.

openGEO-OpenDec 2011View details →
geo24/100

Euglycemic agent-mediated hypothalamic transcriptomic manipulation in the N171-82Q model of Huntington's disease is related to their physiological efficacy

GEO Series GSE39586. Mus musculus. 23 samples. Type: Expression profiling by array.

openGEO-OpenOct 2012View details →

ScienceDex guides

Understand access before you commit

These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record