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1,286
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ShareScore release 0.9.0
Dataset results
1,286 results for “Spinal cord injury”
Axon Regeneration and Functional Recovery from Spinal Cord Injury is Enhanced by Allele-Specific ApoE Neuronal Action through Lrp8
GEO Series GSE283595. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Multiomics profiling of molecular and cellular dynamics of spinal cord injury in a rat [miRNA-seq]
GEO Series GSE295917. Rattus norvegicus. 43 samples. Type: Non-coding RNA profiling by high throughput sequencing.
MicroRNA expression profiling in a mouse spinal cord injury model [P15 and P90, 12h and 3d]
GEO Series GSE89517. Mus musculus. 24 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Transcriptional study of the temporal evolution after severe traumatic spinal cord injury (SCI) and neural progenitor cells (NPCs)-transplantation intervention.
GEO Series GSE183591. Rattus norvegicus. 28 samples. Type: Expression profiling by array.
Next Generation Sequencing of zebrafish spinal cord transcriptomes before and after injury
GEO Series GSE182868. Danio rerio. 49 samples. Type: Expression profiling by high throughput sequencing.
Decoding the m6A expression profiling of spinal cord after spared nerve injury at three time points with RIP-Seq
GEO Series GSE202166. Mus musculus. 24 samples. Type: Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Next Generation Sequencing of zebrafish intraspinal serotonergic neurons in the injury segment and distal segments after spinal cord injury
GEO Series GSE182869. Danio rerio. 11 samples. Type: Expression profiling by high throughput sequencing.
Single cell sequencing of WT and hb-egfaKO zebrafish spinal cord, at 1 week after sham or transection injury.
GEO Series GSE213435. Danio rerio. 4 samples. Type: Expression profiling by high throughput sequencing.
Gene expression microarray analysis of whole mouse hamstring muscles to identify genes promoting the devlopment of neurogenic heterotopic ossifications following spinal cord injury
GEO Series GSE165062. Mus musculus. 16 samples. Type: Expression profiling by array.
Data from: Sleep disordered breathing is associated with brain vascular reactivity in spinal cord injury
Objective: Our goal was to determine the population-level odds of individuals with SCI experiencing fatigue and sleep apnea, to elucidate relationships with level and severity of injury, and to examine associations with abnormal cerebrovascular responsiveness. Methods: We used population-level data, meta-analyses, and primary physiological assessments to provide a large-scale integrated assessment of sleep-related complications after SCI. Population-level and meta-analyses included more than 60,000 able-bodied individuals and more than 1,800 individuals with SCI. Physiological assessments were completed on a homogenous sample of individuals with cervical SCI, and matched controls. We examined the prevalence of 1) self-reported chronic fatigue, 2) clinically-identified sleep apnea, and 3) cerebrovascular responsiveness to changing CO2. Results: Logistic regression revealed a 7-fold elevated odds of chronic fatigue after SCI [OR: 7.9, 95% CI: 3.5-16.2], and that fatigue and trouble sleeping are correlated with the level and severity of injury. We further show that those with SCI experience elevated risk of clinically-defined sleep-disordered breathing in more than 600 individuals with SCI [pooled OR: 3.1, 95% CI: 1.3-7.5]. We confirmed that individuals with SCI experience a high rate of clinically-defined sleep-apnea using primary polysomnography assessments. We then provide evidence using syndromic analysis that sleep-disordered breathing is a factor strongly associated with impaired cerebrovascular responsiveness to CO2 in patients with SCI. Conclusions: Individuals with SCI have an increased prevalence of sleep-disordered breathing, which may partially underpin their increased risk of stroke. There is thus a need to integrate sleep-related breathing examinations into routine care for individuals with SCI.
Acute and chronic effects of motorised dental burr assisted thoracic spinal laminectomy on the functionality and welfare of the contusion spinal cord injury rat model
<p><span>This study focused on acute and chronic effects of the recently established Dental Burr Assisted (DBA) technique to perform laminectomy at T10-T11 vertebral level in a rat model of spinal cord injury (SCI)on animal welfare as well as functionality, and compared it to the conventional technique. The utility as a model of chronic pain, and the effects of SCI on memory was also assessed, using DBA technique and was compared to conventional technique of laminectomy. A total of 24 Crl:WI female rats were assigned randomly to four equal groups- conventionally laminectomised, dental burr assisted laminectomised, conventionally laminectomised with spinal cord contusion and dental burr assisted laminectomised with spinal cord contusion injuries. In a 56 day long study, the animals were tested for bleeding during surgery; Basso Beattie and Bresnahan (BBB) score; body weight changes; Rat Grimace Scale (RGS); light phase open field activity; dark phase home cage activity; sucrose preference as an indicator for hedonistic behaviour; novel object recognition to assess short and long term memory during acute and chronic stages; mechanical allodynia using von Frey filaments; and detailed histopathology of the spinal cord to estimate surviving neuronal number and area of vacuoles at the end of the study. The results indicate that the analgesia provided during post-operative phase did not affect the outcome of the chronic pain model and that, DBA technique can be a functional alternative to the conventional technique to achieve better welfare without affecting the functionality and research outcome in SCI injury studies. </span></p> <p> </p>
Data from: Ergogenic effects of an epidural neuroprosthesis in one individual with spinal cord injury
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Intermittent Theta Burst Stimulation and Repetitive Transcranial Magnetic Stimulation Combined With Robotic Rehabilitation on Ambulation in Spinal Cord Injury Patients
ClinicalTrials.gov study NCT06248476. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Feasibility Trial of an Enhanced Coping-oriented Supportive Programme for Community-dwelling People With Spinal Cord Injury
ClinicalTrials.gov study NCT07170969. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of Three Training Programs on the Cardiovascular Condition of Individuals with Spinal Cord Injury
ClinicalTrials.gov study NCT06627881. IPD Sharing: YES. Countries: 1. Publications: 0.
VIRTUAL WALKING AND TRANSCRANIAL DIRECT CURRENT STIMULATION FOR CHRONIC NEUROPATHIC PAIN DUE TO SPINAL CORD INJURY
ClinicalTrials.gov study NCT06710808. IPD Sharing: NO. Countries: 1. Publications: 0.
Exoskeleton Training at Home to Assist Participants With Spinal Cord Injuries to Perform Ambulatory Functions.
ClinicalTrials.gov study NCT07062575. IPD Sharing: NO. Countries: 1. Publications: 0.
Obesity/Overweight in Persons With Early and Chronic Spinal Cord Injury (SCI)
ClinicalTrials.gov study NCT01467817. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Trial on the Clinical and Socioeconomic Impact of Wearable Exoskeletons for Spinal Cord Injury Rehabilitation in the Spanish Healthcare System
ClinicalTrials.gov study NCT07036107. IPD Sharing: NO. Countries: 1. Publications: 0.
Neurofeedback to Improve Spasticity After Incomplete Spinal Cord Injury
ClinicalTrials.gov study NCT04849676. IPD Sharing: YES. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.