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1,734 results for “probiotics”
The Effect of Probiotics on the Immune Status, Diarrhea and Bacterial Vaginosis Cure Rate Among HIV Patients
ClinicalTrials.gov study NCT00536848. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Exploratory Study to Evaluate the Effects of the Probiotics L. Rhamnosus GR-1 and L. Reuteri RC-14
ClinicalTrials.gov study NCT02139839. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Probiotics for Gallstones in Post-bariatric Surgery Patients：A Prospective Randomized Trial
ClinicalTrials.gov study NCT03247101. IPD Sharing: UNDECIDED. Countries: 1. Publications: 6.
The Influence of Probiotics on Vancomycin-Resistant Enterococcus
ClinicalTrials.gov study NCT00591474. IPD Sharing: Not stated. Countries: 1. Publications: 40.
Microbial Colonization of Oral Probiotics
ClinicalTrials.gov study NCT05375383. IPD Sharing: YES. Countries: 1. Publications: 8.
Clinical Evaluation of Smoker Periodontal Subjects After Lactobacillus-reuteri Probiotics and Antibiotics Therapy
ClinicalTrials.gov study NCT04209777. IPD Sharing: YES. Countries: 1. Publications: 9.
Effect of Prebiotics and/or Probiotics on Uremic Toxins and Inflammation Markers in Peritoneal Dialysis Patients
ClinicalTrials.gov study NCT03770611. IPD Sharing: UNDECIDED. Countries: 1. Publications: 16.
Probiotics and the Microbiome: Clinical Intervention Trial for Anxiety and Depression
ClinicalTrials.gov study NCT02035878. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Effect of Probiotic on Depression
ClinicalTrials.gov study NCT04567147. IPD Sharing: NO. Countries: 1. Publications: 5.
Probiotic Toothpaste to Assess Microbial Colonization
ClinicalTrials.gov study NCT06015958. IPD Sharing: NO. Countries: 1. Publications: 3.
Probiotics for the Prevention of Antibiotic-Associated Diarrhea
ClinicalTrials.gov study NCT02817165. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Prebiotics and Probiotics During Definitive Treatment With Chemotherapy-radiotherapy SCC of the Anal Canal (BISQUIT)
ClinicalTrials.gov study NCT03870607. IPD Sharing: NO. Countries: 1. Publications: 11.
The dose makes the poison: feeding of antibiotic-treated winter honey bees, Apis mellifera, with probiotics and b-vitamins
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Figure 1 from: Senapati S, Dash J, Sethi M, Chakraborty S (2020) Bioengineered probiotics to control SARS-CoV-2 infection. Research Ideas and Outcomes 6: e54802. https://doi.org/10.3897/rio.6.e54802
<p>Figure 1 Bioengineered probiotics to control SARS-CoV-2 infection. (a) Pathogenesis of SARS-CoV-2 depends on interaction between S protein of virus and angiotensin-converting enzyme 2 (ACE2) expressed on the surface of host cells. (b (1)) Engineered probiotics with expression of cell bound ACE2, sequesters the virus by making it bind to the ACE2 receptor on its surface thus inhibiting the viral entry into gut epithelial cells. (b (2)) The secreted form of ACE2 (sACE2) produced by probiotics confiscates the virus by binding to S proteins and masking their binding sites for gut epithelial ACE2. (c) The sACE2 could also have systemic effects due to its absorption into circulation and inhibiting the virus binding at distant organs like lungs.</p>
Probiotic-prebiotic therapy improved constipation and gut motility in Parkinson's disease: Randomised controlled trial
<p><b>Objective</b>: We determined the effectiveness of a multi-strain probiotic-prebiotic combination on constipation symptoms and gut motility in PD patients with constipation.</p> <p><b>Methods: </b>PD<b> </b>patients with constipation (ROME III criteria) were randomized to receive a multi-strain probiotic (<i>Lactobacillus sp</i> and <i>Bifidobacterium sp at </i>30 X 10<sup>9</sup> CFU) with fructo-oligosaccaride (prebiotic) or placebo (fermented milk) twice daily for 8 weeks. Primary outcomes were changes in the presence of constipation symptoms using 9 items of Garrigues Questionnaire (GQ), which included an item on bowel opening frequency. Secondary outcomes were whole gut transit time (WGTT), quality of life (PDQ39-SI), motor (MDS-UPDRS) and non-motor symptoms (NMSS).</p> <p><strong>Results:</strong> Of 55 recruited<b>, </b>48 patients completed the study: 22 received probiotic and 26 received placebo. At 8 weeks, the item on bowel opening frequency (BOF) of GQ showed a higher mean weekly BOF in the probiotic group compared to placebo [4.18 (SD 1.44) vs 2.81(SD 1.06), (mean difference 1.37, 95% CI 0.68, 2.07, uncorrected <i>p</i><0.001). Patients in the probiotic group reported five times higher odds (odds ratio=5.48, 95% CI 1.57, 19.12, uncorrected <i>p</i>=0.008) for increasing BOF (< 3 to 3-5 to >5 times/week) compared to the placebo group. Between-group differences were observed in the WGTT [77.32 (SD 55.35) hours vs 113.54 (SD 61.54) hours], (mean difference -36.22, 95% CI -68.90, -3.54, uncorrected <i>p</i>=0.030) and the mean change in WGTT [58.05 (SD 59.30) vs 20.73 (60.48) hours], (mean difference 37.32, 95% CI 4.00, 70.63, uncorrected <i>p</i>=0.028). No between-groups differences were observed in the NMSS, PDQ39-SI, MDS-UPDRS II, III, scores. Four patients in the probiotics group experienced mild reversible side effects.</p> <p><b>Conclusion:</b> This study provides Class I evidence that consumption of multi-strain probiotics with prebiotic over 8 weeks improved bowel opening frequency and whole gut transit time.</p>
Antimicrobial, Probiotic, and Immunomodulatory Potential of Cannabis sativa Extract and Delivery Systems
<p>Article, Dataset for the article</p> <p> </p> <h2>Abstract</h2> <div>The compounds present in hemp show multidirectional biological activity. It is related to the presence of secondary metabolites, mainly cannabinoids, terpenes, and flavonoids, and the synergy of their biological activity. The aim of this study was to assess the activity of the Henola <span>Cannabis sativae</span> extract and its combinations with selected carriers (polyvinyl caprolactam–polyvinyl acetate–polyethylene glycol graft copolymer, magnesium aluminometasilicate, and hydroxypropyl-β-cyclodextrin) in terms of antimicrobial, probiotic, and immunobiological effects. As a result of the conducted research, the antimicrobial activity of the extract was confirmed in relation to the following microorganisms: <span>Clostridium difficile</span>, <span>Listeria monocytogenes</span>, <span>Enterococcus faecalis</span>, <span>Staphylococcus aureus</span>, <span>Staphylococcus pyrogenes</span>, <span>Escherichia coli</span>, <span>Klebsiella pneumoniae</span>, <span>Salmonella typhimurium</span>, <span>Pseudomonas aereuginosa</span>, and <span>Candida albicans</span> (microorganism count was reduced from ~10<sup>2</sup> CFU mL<sup>−1</sup> to <10 CFU mL<sup>−1</sup> in most cases). Additionally, for the system with hydroxypropyl-β-cyclodextrin, a significant probiotic potential against bacterial strains was established for strains <span>Lactobacillus acidophilus</span>, <span>Lactobacillus casei</span>, <span>Lactobacillus plantarum</span>, <span>Lactobacillus brevis</span>, <span>Lactobacillus rhamnosus</span>, <span>Lactobacillus reuteri</span>, <span>Pediococcus pentosaceus</span>, <span>Lactococcus lactis</span>, <span>Lactobacillus fermentum</span>, and <span>Streptococcus thermophilus</span> (microorganism count was increased from ~10<sup>2</sup> to 10<sup>4</sup>–10<sup>7</sup>). In terms of immunomodulatory properties, it was determined that the tested extract and the systems caused changes in IL-6, IL-8, and TNF-α levels.</div> <div> <div> <div>Keywords: </div> <a href="https://www.mdpi.com/search?q=Cannabis+sativa"><span>Cannabis sativa</span></a>; <a href="https://www.mdpi.com/search?q=cannabidiol">cannabidiol</a>; <a href="https://www.mdpi.com/search?q=antibacterial">antibacterial</a>; <a href="https://www.mdpi.com/search?q=probiotic">probiotic</a>; <a href="https://www.mdpi.com/search?q=immunomodulatory">immunomodulatory</a>; <a href="https://www.mdpi.com/search?q=immunostimulatory">immunostimulatory</a></div> </div>
Raw data for publication: "Effect of Probiotics on Tenebrio molitor Larval Development and Resistance against the Fungal Pathogen Metarhizium brunneum"
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The Effect of Probiotic Supplementation in Drug-resistant Epilepsy Patients
ClinicalTrials.gov study NCT03403907. IPD Sharing: NO. Countries: 0. Publications: 3.
Probiotic Lozenges for Treatment of Recurrent Aphthous Stomatitis
ClinicalTrials.gov study NCT04383236. IPD Sharing: NO. Countries: 0. Publications: 2.
Effect of Probiotic Co-administration With Omega-3 Fatty Acids on NAFLD
ClinicalTrials.gov study NCT03528707. IPD Sharing: NO. Countries: 0. Publications: 1.
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OpenNeuro
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