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1,733 results for “Fatigue”
Influence of Co-diagnosis of Chronic Fatigue Syndrome in Patients With Fibromyalgia.
ClinicalTrials.gov study NCT05323838. IPD Sharing: NO. Countries: 1. Publications: 11.
Cytokine Inhibition in Chronic Fatigue Syndrome Patients
ClinicalTrials.gov study NCT02108210. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Yoga Versus Health Education for the Treatment of Persistent Fatigue in Patients With Post COVID-19 Syndrome
ClinicalTrials.gov study NCT05890599. IPD Sharing: NO. Countries: 1. Publications: 1.
Effect of Vestibular Exercises on Post-Stroke Fatigue
ClinicalTrials.gov study NCT06956183. IPD Sharing: NO. Countries: 1. Publications: 17.
Effect of Kinesio Taping Application in Addition to Pilates Exercises on Core Muscle Thickness, Cognition and Mental Fatigue in Individuals With Non-specific Low Back Pain
ClinicalTrials.gov study NCT06787079. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
Modafinil to Treat Fatigue in Post-Polio Syndrome
ClinicalTrials.gov study NCT00067496. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Data from: Increasing belief but issue fatigue: changes in Australian Household Climate Change Segments between 2011 and 2016
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Data from: Is the association between health-related quality of life and fatigue mediated by depression in patients with multiple sclerosis? A Spanish cross sectional study
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Who develops pandemic fatigue? Insights from latent class analysis
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Data: The effects of general fatigue induced by incremental exercise test and active recovery modes on energy cost, gait variability and stability in male soccer players
<p>Data, code, and movies for Mahaki et al. (2020); The effects of general fatigue induced by incremental exercise test and active recovery modes on energy cost, gait variability and stability in male soccer players. Published in The Journal of Biomechanics (<a href="https://doi.org/10.1016/j.jbiomech.2020.109823">https://doi.org/10.1016/j.jbiomech.2020.109823</a>).</p> <p><strong>Gas data</strong> - contains all Oxygen data plus a script to run the data.</p> <p> - Subjectxx - folder with oxygen data.</p> <p> - GasdataMohammad [type of file: MATLAB code (.m)] - script to analyze the oxygen data. The outcomes have been saved as RestECnet, PWSECnet, and IVTECnet [type of files: MATLAB data (.mat)].</p> <p> - EC_Stat_boxplot [type of file: MATLAB code (.m)] - script to statistically test the hypotheses in terms of energetic cost, to calculate the effect sizes of main effects of Time, Recovery and Interaction effect (Time vs Recovery) and to show the outcome in boxplot together with individual data points (The results have been presented in <strong>Fig 2.</strong>)</p> <p> </p> <p><strong>Kinematic Data</strong> - contains all Kinematic data plus scripts to run the data:</p> <p> - Subjectxx - folder with kinematics data.</p> <p> - Rest_VAR [type of file: MATLAB code (.m)] - script to analyze the kinematics data in the Rest recovery session. The outcomes have been saved as RestVAR [type of file: MATLAB data (.mat)]. The corresponding plots, per subject & per trial, have been saved in the Plots folder.</p> <p> - PWS_VAR [type of file: MATLAB code (.m)] - script to analyze the kinematics data in the PWS recovery session. The outcomes have been saved as PWSVAR [type of file: MATLAB data (.mat)]. The corresponding plots, per subject & per trial, have been saved in the Plots folder.</p> <p> - IVT_VAR [type of file: MATLAB code (.m)] - script to analyze the kinematics data in the IVT recovery session. The outcomes have been saved as IVTVAR [type of file: MATLAB data (.mat)]. The corresponding plots, per subject & per trial, have been saved in the Plots folder.</p> <p> - VAR_Stat_boxplot [type of file: MATLAB code (.m)] - script to statistically test the hypotheses in terms of gait variability (VAR sagittal, frontal, and horizontal) and to show the outcome in boxplot together with individual data points (The results have been presented in <strong>Fig 3.</strong>).</p> <p> - VAR_Sagittal_Stat_boxplot [type of file: MATLAB code (.m)] - script to statistically test the hypotheses in terms of gait variability in sagittal plane, to calculate the effect sizes of main effects of Time, Recovery and Interaction effect (Time vs Recovery), and to show the outcome in boxplot together with individual data points.</p> <p> - VAR_Frontal_Stat_boxplot [type of file: MATLAB code (.m)] - script to statistically test the hypotheses in terms of gait variability in frontal plane, to calculate the effect sizes of main effects of Time, Recovery and Interaction effect (Time vs Recovery), and to show the outcome in boxplot together with individual data points.</p> <p> - VAR_Horizontal_Stat_boxplot [type of file: MATLAB code (.m)] - script to statistically test the hypotheses in terms of gait variability in horizontal plane, to calculate the effect sizes of main effects of Time, Recovery and Interaction effect (Time vs Recovery), and to show the outcome in boxplot together with individual data points.</p> <p> - normalizetimebase [type of file: MATLAB code (.m)] – function to normalize VAR from 0 to 100% of the gait cycle.</p> <p> - VAR_Sagittal [type of file: JASP/Jamovie files (.jasp/.omv)] - file to statistically test gait variability in sagittal plane. Imported data have been saved as VAR_Sagittal [type of file: Excell file (.csv)].</p> <p> - VAR_Frontal [type of file: JASP/Jamovie files (.jasp/.omv)] - file to statistically test gait variability in frontal plane. Imported data have been saved as VAR_Frontal [type of file: Excell files (.csv)].</p> <p> - VAR_Horizontal [type of file: JASP/Jamovie files (.jasp/.omv)] - file to statistically test gait variability in horizontal plane. Imported data have been saved as VAR_Horizontal [type of file: Excell file (.csv)].</p> <p> + Trunk Stability - folder includes all outcomes and codes in terms of gait stability:</p> <p> -Thoracic [type of file: Excell file (.xlsx)] - general file includes all outcomes in terms of gait stability.</p> <p> - LDS_Stat_boxplot [type of file: MATLAB code (.m)] - script to statistically test the hypotheses in terms of gait stability (λ sagittal, λ frontal, and λ horizontal) and to show the outcome in boxplot together with individual data points (The results have been presented in <strong>Fig 5.</strong>).</p> <p> - LDS_Sagittal_Stat_boxplot [type of file: MATLAB code (.m)] - script to statistically test the hypotheses inn terms of gait stability in sagittal plane, to calculate the effect sizes of main effects of Time, Recovery and Interaction effect (Time vs Recovery), and to show the outcome in boxplot together with individual data points.</p> <p> - LDS_Frontal_Stat_boxplot [type of file: MATLAB code (.m)] - script to statistically test the hypotheses in terms of gait stability in frontal plane, to calculate the effect sizes of main effects of Time, Recovery and Interaction effect (Time vs Recovery), and to show the outcome in boxplot together with individual data points.</p> <p> - LDS_Horizontal_Stat_boxplot [type of file: MATLAB code (.m)] - script to statistically test the hypotheses in terms of gait stability in horizontal plane, to calculate the effect sizes of main effects of Time, Recovery and Interaction effect (Time vs Recovery), and to show the outcome in boxplot together with individual data points.</p> <p> - Rest_LDS_Sagittal [type of file: Excell file (.xlsx)] - file includes LDS outcomes in the Rest recovery session and in the sagittal plane.</p> <p> - Rest_LDS_Frontal [type of file: Excell file (.xlsx)] - file includes LDS outcomes in the Rest recovery session and in the frontal plane.</p> <p> - Rest_LDS_Horizontal [type of file: Excell file (.xlsx)] - file includes LDS outcomes in the Rest recovery session and in the horizontal plane.</p> <p> - PWS_LDS_Sagittal [type of file: Excell file (.xlsx)] - file includes LDS outcomes in the PWS recovery session and in the sagittal plane.</p> <p> - PWS_LDS_Frontal [type of file: Excell file (.xlsx)] - file includes LDS outcomes in the PWS recovery session and in the frontal plane.</p> <p> - PWS_LDS_Horizontal [type of file: Excell file (.xlsx)] - file includes LDS outcomes in the PWS recovery session and in the horizontal plane.</p> <p> - IVT_LDS_Sagittal [type of file: Excell file (.xlsx)] - file includes LDS outcomes in the IVT recovery session and in the sagittal plane.</p> <p> - IVT_LDS_Frontal [type of file: Excell file (.xlsx)] - file includes LDS outcomes in the IVT recovery session and in the frontal plane.</p> <p> - IVT_LDS_Horizontal [type of file: Excell file (.xlsx)] - file includes LDS outcomes in the IVT recovery session and in the horizontal plane.</p> <p> - LDS_sagittal [type of files: JASP/Jamovie files (.jasp/.omv)] - file to statistically test gait stability in sagittal plane. Imported data have been saved as LDS_sagittal [type of file: Excell file (.csv)].</p> <p> - LDS_frontal [type of files: JASP/Jamovie files (.jasp/.omv)] - file to statistically test gait stability in frontal plane. Imported data have been saved as LDS_frontal [type of file: Excell file (.csv)].</p> <p> - LDS_horizontal [type of files: JASP/Jamovie file (.jasp/.omv)] - file to statistically test gait stability in horizontal plane. Imported data have been saved as LDS_horizontal [type of file: Excell file (.csv)].</p> <p> </p> <p><strong>Movies</strong> –contains some movies [type of files: .mp4] to show the Noraxon calibration, IMUs placement on body segments, fatigue protocol, walking at PWS, and resting metabolic cost measurement.</p> <p> </p> <p><strong>The characteristics of participants</strong> [type of file: Excell file (.xlsx)] – file includes 4 sheets:</p> <p> - Sheet 1 includes height (cm), weight (kg), age (year), BMI, and body fat percentage of each participant.</p> <p> - Sheets 2-4 include the physiological parameters of each participant during IVT, PWS, and Rest recovery modes. The physiological parameters such as Vo2, Vo2max, HR, and RER of each participant have been reported during rest (i.e. sitting position) and incremental exercise test.</p> <p> </p>
Multi-partner benchmark experiment of fatigue crack growth measurements from GDR 3651 FATACRACK
<p>The dataset presents a synthesis of an experimental benchmark performed in the context of the French national research network GDR FATACRACK . A sample has been designed to produce mixed-mode crack propagation and variation of small scale yielding conditions. Two geometries and two maximum load levels are defined for the two tested materials: a stainless steel and an aluminum alloy. Around ten participants performed experiments using their usual instrumentation. Among the eight possible parameter sets, three are selected for which detailed results are presented. A satisfying overall agreement is obtained. But, some discrepancies are evidenced due either to limitations of the instrumentation or simply because from one lab to the other the applied load is not exactly the same. The results obtained by all the participants as well as the description of their testing setups and measurement tools are collected in this dataset. It includes crack path, stress intensity factor range and crack growth rate measurement for the selected configurations. </p>
Effects of hot-wet storage aging, CNT-integration and damping layer interposition on static and fatigue interlaminar shear response of a UD Graphite/Epoxy material system
<p>The present work aims at experimental quantification of the effect of hot-wet storage aging on the static and<br> fatigue interlaminar shear response of three UD Graphite-Epoxy based material systems: a control laminate, a<br> CNT-treated laminate and a lamination including an embedded damping veil. In this context, specimens have<br> been fabricated and tested for determination of the interlaminar shear strength (ILSS) according to the relevant<br> ASTM standard, and the effects of the above mentioned constituents on the response of non-aged (RT) and aged<br> (HW) specimens have been investigated. The experimental data, presented in batch mode, indicated that aging<br> leads to severe degradation of the interlaminar shear strength and relevant fatigue endurance of all material<br> systems, whereas the CNT-treated laminate appeared to be the most sensitive configuration. In the case of nonaged specimens, CNT-treatment led to larger failure strains and a clear bilinear response, while all three material<br> systems exhibited similar values of interlaminar shear strength.</p>
Fatigue resistant jaw muscles facilitate long-lasting courtship behavior in the southern alligator lizard (Elgaria multicarinata)
<p>The southern alligator lizard (<i>Elgaria multicarinata</i>) exhibits a courtship behavior during which the male firmly grips the female's head in his jaws for many hours at a time. This extreme behavior counters the conventional wisdom that reptile muscles are fast to fatigue and incapable of powering high endurance behaviors. We conducted <i>in situ</i> experiments in which the jaw-adductor muscles of lizards were stimulated directly while bite force was measured simultaneously with a force transducer. Fatigue tests were performed by supramaximally and bilaterally stimulating the muscles for several minutes with a series of tetanic trains. Our results show that a substantial sustained force gradually develops during the first few minutes of the fatigue test. This sustained force persists after peak tetanic forces have declined to a fraction of their initial magnitude. The observed sustained force during <i>in situ</i> fatigue tests is consistent with the natural courtship behavior of these lizards and likely reflects physiological specialization. The results of molecular analysis reveal that the jaw-adductor muscles contain masticatory myosin and tonic myosin fibers. We propose that the presence of tonic fibers may explain the unusual sustained force properties during mate-holding behavior. The characterization of muscle properties that facilitate extreme performance in specialized systems may help reveal general mechanisms, especially when done in light of convergently evolved systems exhibiting similar performance characteristics.</p>
Data from: Impact of uniaxial tensile fatigue on the evolution of microscopic and mesoscopic structure of carbon black filled natural rubber
This investigation addresses the evolution of the microscopic and mesoscopic structures distribution, and micro-defects of carbon black (CB) filled natural rubber (NR) under uniaxial tensile condition during the fatigue process. NR was filled with three different grades CB respectively, in order to understand the impact of the structural degree and specific surface areas of CB and fatigue degree on the Payne effect. It was found that Payne effect was initially suppressed and then enhanced with increasing the degree of fatigue. The decrease of the storage modulus in the low strain area was attributed to the CB network destruction and the breakdown of the matrix cross-linking network in the early fatigue stage. However, with further increasing the degree of fatigue, the spatial rearrangement of CB aggregates with the orientation of molecular chains between adjacent CB aggregates will result in the mechanical reinforcement before the appearance of micro-defects. Moreover, it has been demonstrated that the structural degree of CB has a stronger impact on the mesoscopic structures than the specific surface area of CB during tensile fatigue process.
Data from: Fatiguing effects of indirect vibration stimulation in upper limb muscles- post and during isometric contractions superimposed on upper limb vibration
Whole body vibration and upper limb vibration (ULV), continues to gain popularity as exercise intervention for rehabilitation and sports applications. However, the fatiguing effects of indirect vibration stimulation are not yet fully understood. We investigated the effects of ULV stimulation superimposed on fatiguing isometric contractions using a purpose developed upper limb stimulation device. Thirteen healthy volunteers were exposed to both ULV superimposed to fatiguing isometric contractions (V) and isometric contractions alone- Control (C). Both Vibration (V) and Control (C) exercises were performed at 80% of the maximum voluntary contractions. The stimulation used was 30 Hz frequency of 0.4 mm amplitude. Surface-electromyographic (EMG) activity of the Biceps Brachii, Triceps Brachii, and Flexor Carpi Radialis were measured. EMG amplitude (EMGrms) and mean frequency (MEF) were computed to quantify muscle activity and fatigue levels. All muscles displayed significantly higher reduction in MEFs and corresponding significant increase in EMGrms with the V than the Control, during fatiguing contractions (P < 0.05). Post vibration, all muscles showed higher levels of MEFs after recovery compared to the control. Our results show that near maximal isometric fatiguing contractions superimposed on vibration stimulation lead to a higher rate of fatigue development compared to the isometric contraction alone in the upper limb muscles. Results also show higher manifestation of mechanical fatigue post treatment with vibration compared to the control. Vibration superimposed on isometric contraction not only seems to alter the neuromuscular function during fatiguing efforts by inducing higher neuromuscular load but also post vibration treatment.
Data from: Recruitment of reviewers is becoming harder at some journals: a test of the influence of reviewer fatigue at six journals in ecology and evolution
Background: It is commonly reported by editors that it has become harder to recruit reviewers for peer review and that this is because individuals are being asked to review too often and are experiencing reviewer fatigue. However, evidence supporting these arguments is largely anecdotal. Main body: We examine responses of individuals to review invitations for six journals in ecology and evolution. The proportion of invitations that lead to a submitted review has been decreasing steadily over 13 years (2003–2015) for four of the six journals examined, with a cumulative effect that has been quite substantial (average decline from 56% of review invitations generating a review in 2003 to just 37% in 2015). The likelihood that an invitee agrees to review declines significantly with the number of invitations they receive in a year. However, the average number of invitations being sent to prospective reviewers and the proportion of individuals being invited more than once per year has not changed much over these 13 years, despite substantial increases in the total number of review invitations being sent by these journals—the reviewer base has expanded concomitant with this growth in review requests. Conclusions: The proportion of review invitations that lead to a review being submitted has been declining steadily for four of the six journals examined here, but reviewer fatigue is not likely the primary explanation for this decline.
Data from: Patients with primary biliary cholangitis and fatigue present with depressive symptoms and selected cognitive deficits, but with normal attention performance and brain structure
Background: In primary biliary cholangitis (PBC) fatigue is a major clinical challenge of unknown etiology. By demonstrating that fatigue in PBC is associated with an impaired cognitive performance, previous studies have pointed out the possibility of brain abnormalities underlying fatigue in PBC. Whether structural brain changes are present in PBC patients with fatigue, however, is unclear. To evaluate the role of structural brain abnormalities in PBC patients severely affected from fatigue we, therefore, performed a case-control cerebral magnetic resonance imaging (cMRI) study and correlated changes of white and grey brain matter with the cognitive and attention performance. Methods: 20 female patients with PBC and 20 female age-matched controls were examined in this study. The assessment of fatigue, psychological symptoms, cognitive and attention performance included clinical questionnaires, established cognition tests and a computerized test battery of attention performance. T1-weighted cMRI and diffusion tensor imaging (DTI) scans were acquired with a 3 Tesla scanner. Structural brain alterations were investigated with voxel-based morphometry (VBM) and DTI analyses. Results were correlated to the cognitive and attention performance. Results: Compared to healthy controls, PBC patients had significantly higher levels of fatigue and associated psychological symptoms. Except for an impairment of verbal fluency, no cognitive or attention deficits were found in the PBC cohort. The VBM and DTI analyses revealed neither major structural brain abnormalities in the PBC cohort nor correlations with the cognitive and attention performance. Conclusions: Despite the high burden of fatigue and selected cognitive deficits, the attention performance of PBC patients appears to be comparable to healthy people. As structural brain alterations do not seem to be present in PBC patients with fatigue, fatigue in PBC must be regarded as purely functional. Future studies should evaluate, whether functional brain changes underlie fatigue in PBC.
Data from: The interaction of fatigue cracks with a residual stress field using thermoelastic stress analysis and synchrotron x-ray diffraction experiments
This article presents an experimental study on the fatigue behaviour of cracks emanating from cold-expanded holes utilising thermoelastic stress analysis (TSA) and synchrotron x-ray diffraction (SXRD) techniques with the aim of resolving the long-standing ambiguity in the literature regarding potential relaxation, or modification, of beneficial compressive residual stresses as a result of fatigue crack propagation. The crack growth rates are found to be substantially lower as the crack tip moved through the residual stress zone induced by cold expansion. The TSA results demonstrated that the crack tip plastic zones were reduced in size by the presence of the residual compressive stresses induced by cold expansion. The crack tip plastic zones were found to be insignificant in size in comparison to the residual stress zone resulting from cold expansion, which implied that they were unlikely to have had a notable impact on the surrounding residual stresses induced by cold expansion. The residual stress distributions measured along the direction of crack growth, using SXRD, showed no signs of any significant stress relaxation or redistribution, which validates the conclusions drawn from the TSA data. Fractographic analysis qualitatively confirmed the influence on crack initiation of the residual stresses induced by the cold expansion. It was found that the application of single compressive overload caused a relaxation, or reduction in the residual stresses, which has wider implications for improving the fatigue life.
Data from: Fascicles from energy-storing tendons show an age-specific response to cyclic fatigue loading
Some tendons, such as the human Achilles and equine superficial digital flexor tendon (SDFT), act as energy stores, stretching and recoiling to increase efficiency during locomotion. Our previous observations of rotation in response to applied strain in SDFT fascicles suggest a helical structure, which may provide energy-storing tendons with a greater ability to extend and recoil efficiently. Despite this specialization, energy-storing tendons are prone to age-related tendinopathy. The aim of this study was to assess the effect of cyclic fatigue loading (FL) on the microstructural strain response of SDFT fascicles from young and old horses. The data demonstrate two independent age-related mechanisms of fatigue failure; in young horses, FL caused low levels of matrix damage and decreased rotation. This suggests that loading causes alterations to the helix substructure, which may reduce their ability to recoil and recover. By contrast, fascicles from old horses, in which the helix is already compromised, showed greater evidence of matrix damage and suffer increased fibre sliding after FL, which may partially explain the age-related increase in tendinopathy. Elucidation of helix structure and the precise alterations occurring owing to both ageing and FL will help to develop appropriate preventative and repair strategies for tendinopathy.
Carbohydrate Mouth Rinse Reduces Perceived Exertion and Mental Fatigue, and Improves Technical Actions during Small-Sided Soccer Games
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