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1,315 results for “aberration”
Elucidating oncogenic effects of androgen signaling in prostate tumorigenesis through aberrant activation of IGF1 and WNT signaling pathways [RNA-Seq]
GEO Series GSE164967. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Acquired Genomic Copy Number Aberrations and Survival in Adult Acute Myelogenous Leukemia
GEO Series GSE23452. Homo sapiens. 226 samples. Type: SNP genotyping by SNP array; Genome variation profiling by SNP array.
The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3
GEO Series GSE41174. Mus musculus. 11 samples. Type: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing.
Aberrant methylation-mediated silencing of microRNAs contributes to HPV-induced anchorage independence [miR-Agilent]
GEO Series GSE78278. Homo sapiens. 60 samples. Type: Non-coding RNA profiling by array.
Single cell transcriptome reveals aberrant macrophage subtype and its regulatory genes in critical COVID-19 patients
<p>allGOnKEGG_June2020.gmt: Tab delimited file describing gene sets from KEGG and GO pathways</p> <p>Control1_Deprez_exprMatrix.tsv: COntrol dataset 1</p> <p>Contro2_Madissoon_lung.cellxgene.h5ad: Control dataset 2</p> <p>COVID19COMORBID_DATABASE_UDDINLAB.xls: Comorbid gene dataset. The genes which are upregulated in severe COVID19-comorbid conditions</p> <p>Final_LUNGMarker_DB_UDDINLAB.xlsx: Database consisting of canonical markers for cells associated to human lung region constructed by combining cell marker databases and thorough literature</p> <p>All files starting with GSM: Matrix(h5 file) and annotation file for bronchoalveolar lavage fluid (BALF) from 6 severe and 3 moderate COVID-19 patients and 3 healthy control (From Liao et al., 2020: PMID: 32398875)</p> <p>Human_cell_markers.txt: Markers from CellMarker database</p> <p>PanglaoDB_markers_27_Mar_2020.tsv: Markers from PanglaoDB database</p> <p>All files starting with sample: Sample Seurat processed file (sample.rds); Sample file for executing gene enrichment analysis; Sample file for lung marker database</p> <p>All files starting with Validation: Validation files used in the paper.</p> <p></p>
Data from: Canine mammary tumours are affected by frequent copy number aberrations, including amplification of MYC and loss of PTEN
Background: Copy number aberrations frequently occur during the development of many cancers. Such events affect dosage of involved genes and may cause further genomic instability and progression of cancer. In this survey, canine SNP microarrays were used to study 117 canine mammary tumours from 69 dogs. Results: We found a high occurrence of copy number aberrations in canine mammary tumours, losses being more frequent than gains. Increased frequency of aberrations and loss of heterozygosity were positively correlated with increased malignancy in terms of histopathological diagnosis. One of the most highly recurrently amplified regions harbored the MYC gene. PTEN was located to a frequently lost region and also homozygously deleted in five tumours. Thus, deregulation of these genes due to copy number aberrations appears to be an important event in canine mammary tumour development. Other potential contributors to canine mammary tumour pathogenesis are COL9A3, INPP5A, CYP2E1 and RB1. The present study also shows that a more detailed analysis of chromosomal aberrations associated with histopathological parameters may aid in identifying specific genes associated with canine mammary tumour progression. Conclusions: The high frequency of copy number aberrations is a prominent feature of canine mammary tumours as seen in other canine and human cancers. Our findings share several features with corresponding studies in human breast tumours and strengthen the dog as a suitable model organism for this disease.
Figures 1-2 from: Fikácek M, Ryndevich S, Jia F (2012) An aberrant species of Nipponocercyon from Sichuan, China (Coleoptera, Hydrophilidae, Sphaeridiinae). ZooKeys 214: 13-27. https://doi.org/10.3897/zookeys.214.3437
Figures 1-2 - General habitus of Nipponocercyon sichuanicus. 1 dorsal view 2 lateral view.
Figure 4 from: Stocchino G, Sluys R, Manconi R (2014) A new and aberrant species of Dugesia (Platyhelminthes, Tricladida, Dugesiidae) from Madagascar. ZooKeys 425: 71-88. https://doi.org/10.3897/zookeys.425.7811
Figure 4 - Dugesia bifida. Schematic horizontal reconstruction of the copulatory apparatus.
Figure 7 from: Stocchino G, Sluys R, Manconi R (2014) A new and aberrant species of Dugesia (Platyhelminthes, Tricladida, Dugesiidae) from Madagascar. ZooKeys 425: 71-88. https://doi.org/10.3897/zookeys.425.7811
Figure 7 - Dugesia bifida. A metaphasic plate B karyogram C idiogram.
Figures 1-3 in A male Pelegrina galathea with an aberrant palpus
Figures 1-3. Male Pelegrina galathea from Coolidge, Hamilton County, Kansas. 1, Right male palpus, ventral view, with broken embolus. 2, Left male palpus, ventral view, with normal embolus. 3, Dorsal view of the specimen, length 4.2 mm.
Aberrant Synaptic Plasticity in Cocaine Use Disorder: A 11C-UCB-J PET Study
ClinicalTrials.gov study NCT04721418. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Aberrant Gene Expression Prostate Carcinoma
ClinicalTrials.gov study NCT00868803. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Lucitanib (E3810) in Patients With Advanced Cancer and FGFR, VEGFR, or PDGFR Pathway Aberrations
ClinicalTrials.gov study NCT02747797. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Influence of Meibomian Gland Expression on Corneal Aberrations in MGD Patients
ClinicalTrials.gov study NCT05028491. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Effects of Therapeutic Recreation Activities on Aberrant Behaviours of Individuals With Intellectual Disabilities
ClinicalTrials.gov study NCT04546464. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Analysis of I-Trace High Order Aberrations Induced by Wavefront Optimized Ablation Profiles
ClinicalTrials.gov study NCT04452448. IPD Sharing: NO. Countries: 1. Publications: 0.
Measurement of High Order Aberrations in Late Stages Keratoconus
ClinicalTrials.gov study NCT01295164. IPD Sharing: NO. Countries: 1. Publications: 0.
A Prospective Clinical Research Project Evaluating The Effects of Soft Contact Lenses on Higher Order Visual Aberrations
ClinicalTrials.gov study NCT00344864. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Comparison of Corneal Aberrations in Subjects With Contralateral AcrySof IQ Toric Intraocular Lens (IOL) and AcrySof IQ IOL With Limbal Relaxing Incision (LRI)
ClinicalTrials.gov study NCT01045733. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Osimertinib Plus Dalpiciclib in Patients With EGFR-mutant, CDK4/6 Pathway Aberrant, Advanced Non-small Cell Lung Cancer Following Acquired Resistance to Third-generation EGFR TKI: a Phase II Trial
ClinicalTrials.gov study NCT06363734. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.