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636 results for “anxiety and depression”
Mesenchymal Stromal Cells Alleviate Depressive and Anxiety-like Behaviors via a Lung Vagal-to-Brain Axis in Male Mice
GEO Series GSE246290. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Depression and Anxiety-Induced Metabolic Reprogramming Promotes Hepatocellular Carcinoma Progression through CBX5 Lactylation: Involvement of Taurocholate and PHGDH-Mediated Ferroptosis
GEO Series GSE282171. Mus musculus; Homo sapiens. 28 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Dataset related to the article "Self-Care and Quality of Life in Patients with Chronic Cardiovascular Diseases: the Role of Anxiety, Depression and Perceived Distress"
<p>This record contains raw data related to the article "Self-Care and Quality of Life in Patients with Chronic Cardiovascular Diseases: the Role of Anxiety, Depression and Perceived Distress".</p> <p>ABSTRACT:</p> <p><strong>Aim: </strong>To explore the relationship between self-care, psychological status, and quality of life in patients with chronic cardiovascular diseases.</p> <p><strong>Background:</strong> Psychological disorders are frequent among patients with chronic cardiovascular diseases, who also need to perform self-care to manage their condition. Both psychological status and self-care seem to affect the quality of life, but the relationship between these three elements is not completely understood.</p> <p><strong>Methods: </strong>397 patients with chronic cardiovascular disease were enrolled. All participants completed a self-administered test battery comprising GAD-7 (symptoms of anxiety), PHQ-9 (symptoms of depression), PSS (perceived distress), EQ5D (quality of life), and SCCII (self-care). Paths analysis was conducted.</p> <p><strong>Results: </strong>In people with chronic cardiovascular diseases, self-care and quality of life are indirectly linked via perceived distress as the mediating factor.</p> <p><strong>Conclusions: </strong>To our knowledge, this is the first study to assess the mediating role of psyhological well-being in the relationship between self-care and quality of life in patients with chronic cardiovascular diseases. Findings indicate that, in this population, self-care affects quality of life with the moderating role of perceived distress, highlighting the importance of enhancing the cooperation between nurses and psychologists in order to alleviate distress and improve quality of life in these patients.</p> <p><span><strong>THIS DATASET IS NOT PUBLIC. IS AVAILABLE UPON REASONABLE REQUEST TO THE CORRESPONDING AUTHOR</strong></span></p>
Dataset related to the article "Examination of the best cut-off points of PHQ-2 and GAD-2 for detecting depression and anxiety in Italian cardiovascular inpatients"
<p>This record contains raw data related to the article "Examination of the best cut-off points of PHQ-2 and GAD-2 for detecting depression and anxiety in Italian cardiovascular inpatients"</p>
Dataset related to the article "Depressive and Anxiety Symptoms Screening in Cardiac Inpatients: A Virtuous Italian Approach to Psychocardiology"
<p>This record contains raw data related to the article "Depressive and Anxiety Symptoms Screening in Cardiac Inpatients: A Virtuous Italian Approach to Psychocardiology"</p>
Differences in depression, anxiety and stress disorders between fibromyalgia associated with rheumatoid arthritis and primary fibromyalgia
<p>Fibromyalgia (FM) was frequently observed in patients with rheumatoid arthritis<br> (RA). We aimed to evaluate the differences in psychiatric comorbidities and life adversities<br> between patients with Rheumatoid arthritis þ FM (secondary fibromyalgia<br> [SFM]) and people with primary FM (PFM). In a cross‐sectional, observational study,<br> patients with PFM and SFM underwent a structured interview for the lifetime diagnosis<br> of major depression (MDD), panic disorder (PD) and post‐traumatic stress<br> disorder (PTSD) and were assessed for childhood/adulthood adversities and FMrelated<br> symptoms severity. Thirty patients withPFMand 40 withSFMwere recruited.<br> The univariate analysis showed that the lifetime rates of MDD were significantly<br> higher in PFM versus SFM (76.7 % and 40%, respectively, p < 0.003), as well as the<br> rates of PD (50 % and 15%, respectively, p < 0.003), whereas there was no difference<br> in PTSD rates. The rates of sexual abuse and physical neglect were significantly higher<br> in PFM patients versus SFM patients (p < 0.005 and p < 0.023). Life events occurring<br> before FM onset were different in PFM and SFM groups. In the logistic regression<br> model, lifetime PD and physical neglect remain independent risk factors for PFM.<br> PFM and SFM differ in psychiatric comorbidities and environmental adversities,<br> suggesting that common pathogenesis may develop through different pathways.</p>
Effects of Mutuality, Anxiety, and Depression on Quality of Life of Patients With Heart Failure: A Cross-Sectional Study
<p>Dellafiore F, Arrigoni C, Palpella F, Diazzi A, Orrico M, Magon A, Pittella F, Caruso R. Effects of Mutuality, Anxiety, and Depression on Quality of Life of Patients With Heart Failure: A Cross-Sectional Study. Creat Nurs. 2021 Aug 1;27(3):181-189. doi: 10.1891/CRNR-D-20-00025. PMID: 34493639.</p> <p>This study aimed to describe the impact of mutuality, anxiety, and depression on quality of life (QoL) in patients with heart failure (HF) using cross-sectional, convenient, and consecutive sampling. A total of 97 patients were recruited. Socio-demographic and clinical variables and self-report measures of anxiety, depression, mutuality, and QoL were collected. The results highlighted the pivotal role of mutuality (specifically the domain of shared values between patients and their caregivers) in determining perceptions of physical health. Conversely, depression was a negative determinant of perceptions of both physical and mental health. Future research is needed to describe in-depth and longitudinally the associations between mutuality and QoL in patients with HF.</p>
Spirituality, anxiety, and depression in health professionals
<p><span><span>The relationship among spirituality, anxiety, and depression in health professionals in a Greek regional general hospital.</span></span></p>
Data used for the scientific work "Effectiveness of Cognitive Behavioral Therapy in naturalistic settings for patients with and without personality disorders: a comparative study of the English IAPT and the Italian inTHERAPY programs on anxiety and depression symptoms"
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Dataset related to the article "Associations of Preoperative Self-rated Symptoms of Anxiety and Depression on Length of Hospital Stay and Long-term Quality of Life in Patients Undergoing Cardiac Surgery"
<p>This record contains raw data related to the article "Associations of Preoperative Self-rated Symptoms of Anxiety and Depression on Length of Hospital Stay and Long-term Quality of Life in Patients Undergoing Cardiac Surgery"</p> <p><strong>ABSTRACT</strong></p> <p><strong>Background: </strong>Anxiety and depression are often associated with cardiovascular diseases. Nevertheless, few study authors have investigated psychological effects on immediate and long-term cardiac surgery-related outcomes, such as surgical complications, length of hospital stay (LOS), and long-term health-related quality of life (HRQoL).</p> <p><strong>Objectives: </strong>The aims of this study were to (a) investigate the role of preoperative symptoms of anxiety and depression in predicting LOS in a sample of surgical patients and (b) evaluate the impact of preoperative symptoms of anxiety and depression on the patients' HRQoL 3 months after surgery.</p> <p><strong>Methods: </strong>One hundred fifty-one patients waiting for surgery were included. To evaluate symptoms of anxiety and depression, the Hospital Anxiety and Depression Scale was used. Multiple regression analyses were conducted to evaluate the impact of both clinical and psychological factors on LOS, whereas quantile regression was performed to assess their effect on the patients' HRQoL 3 months after surgery.</p> <p><strong>Results: </strong>The multiple regression shows that EuroSCORE, length of endotracheal intubation, and anxiety symptoms predict LOS. The multiple quantile regression analyses also show that both symptoms of anxiety and depression predict a negative HRQoL up to 3 months after surgery.</p> <p><strong>Conclusion: </strong>Preoperative symptoms of anxiety predict the patients' LOS, and both symptoms of anxiety and depression predict a scarce HRQoL 3 months after cardiac surgery. These results suggest the need for implementing presurgical in-hospital screening procedures for both symptoms of anxiety and depression. Finally, focused psychological interventions should be implemented for reducing inpatients' hospital LOS and improving their future quality of life.</p>
The mediating role of psychological inflexibility in the relationship between anxiety, depression, and emotional eating in adult individuals with obesity
<p>The aim of this cross-sectional study is to investigate the role of psychological inflexibility in the relationship between anxiety and depression and emotional eating in a sample of 123 inpatient Italian adult individuals with obesity. Participants completed the Anxiety and Depression subscales of the Psychological General Well-Being Inventory, the Acceptance and Action Questionnaire, and the Emotional Eating subscale of the Dutch Eating Behavior Questionnaire to assess anxiety and depression, psychological inflexibility, and emotional eating, respectively. Results showed that the indirect effect of PGWBI-A on DEBQ-EE through AAQ-II was significant [<em>b</em> = −0.0155; SE = 0.076; 95% BC-CI (−0.0320 to −0.023)]. Similarly, the indirect effect of PGWBI-D on DEBQ-EE through AAQ-II was significant [<em>b</em> = −0.0383; SE = 0.0207; 95% BC-CI (−0.0810 to −0.0002)]. These findings may help to plan and develop specific psychological interventions aimed at addressing emotional eating through targeting psychological inflexibility to be included in obesity treatment programs.</p>
Describing post-traumatic stress disorder and its associations with depression, anxiety and insomnia: a descriptive study in Italian adults with Marfan syndrome during the COVID-19 third wave
<p>Udugampolage N, Caruso R, Magon A, Conte G, Callus E, Taurino J, Pini A. Describing post-traumatic stress disorder and its associations with depression, anxiety and insomnia: a descriptive study in Italian adults with Marfan syndrome during the COVID-19 third wave. BMJ Open. 2022 Dec 12;12(12):e067024. doi: 10.1136/bmjopen-2022-067024. PMID: 36523249; PMCID: PMC9748516.</p> <p>Abstract</p> <p><strong>Objective: </strong>The evaluation of post-traumatic stress disorder (PTSD), depression, anxiety and insomnia in patients with Marfan syndrome (MFS) during the third wave of the COVID-19 pandemic in a region of northern Italy (Lombardy) and the investigation of which mental health, sociodemographic and clinical factors were associated with PTSD.</p> <p><strong>Design: </strong>Descriptive observational design with cross-sectional data collection procedure.</p> <p><strong>Setting: </strong>A single Italian MFS-specific specialised and reference centre in Lombardy (Italy) between February and April 2021.</p> <p><strong>Participants: </strong>112 adults with MFS. The majority of participants were female (n=64; 57.1%), with a high school diploma (n=52; 46.4%) and active workers (n=66; 58.9%). The mean age was 41.89 years (SD=14.00), and the mean time from diagnosis was 15.18 years (SD=11.91).</p> <p><strong>Primary and secondary outcomes: </strong>Descriptive statistics described PTSD, which was the primary outcome, as well as depression, anxiety and insomnia, which were the secondary outcomes. Four linear regression models described the predictors of PTSD total score and its three domains: avoidance, intrusion and hyperarousal.</p> <p><strong>Results: </strong>One out of 10 patients with MFS had mild psychological symptoms regarding depression, anxiety and insomnia, and scores of PTSD that indicated clinical worries about the mental health status. The presence of PTSD was mainly predicted by anxiety (β=0.647; p<0.001), being older, taking psychoactive medication and being unemployed.</p> <p><strong>Conclusion: </strong>Depression, anxiety and insomnia should be monitored in patients with MFS in order to minimise PTSD insurgence. Specific psychosocial interventions should be developed and tested for this population and adopted in clinical practice, given the relevance of mental health outcomes during the pandemic.</p>
Dataset for manuscript Internet-administered, guided, low-intensity cognitive behavioural therapy for depression and/or generalized anxiety in parents of children treated for cancer: A single arm feasibility trial (ENGAGE)
<p>Dataset supporting findings in the manuscript <strong>Internet-administered, guided, low-intensity cognitive behavioural therapy for depression and/or generalized anxiety in parents of children treated for cancer: A single arm feasibility trial (ENGAGE). </strong>The study was prospectively registered in the ISRCTN registry (ISRCTN 57233429).</p>
Metacognition, depression, anxiety
<p>Cross-sectional and prospective data in clinical sample.</p>
Prevalence, injury-, and non-injury-related predictors of anxiety and depression in polytrauma patients – A 20 year follow-up study
<p class="CxSpFirst"><b>Introduction</b></p> <p class="CxSpMiddle">Survival rate after polytrauma increased over the past decades resulting in an increase of long-term complications. These include physical and psychiatric impairments. The aim of this study was to describe the prevalence and risk factors for developing depression and anxiety more than twenty years after polytrauma.</p> <p class="CxSpMiddle"><b>Methods</b></p> <p class="CxSpMiddle">We contacted patients who were treated due to a polytrauma between 1973 and 1990 at one level 1 trauma centre after more than 20 years. These patients received a self-administered questionnaire, to assess symptoms of depression and anxiety. Prediction based on multivariate logistic regression models include injury related and non-injury related factors to determine risk factors for the development of depression and anxiety.</p> <p class="CxSpMiddle"><b>Results</b></p> <p class="CxSpMiddle">Patients included in this study (n=337) had a mean ISS of 20.3 (4 to 50) points. In total, 173 (51.3%) showed psychiatric complications (depression n=163, 48.2%; anxiety n=14, 4.1%). The maximum Abbreviated Injury Scale (MAIS) for head was predictive for depression (OR 1.5 95%CI 1.1 to 5.4, p = 0.0445) as was the MAIS for spine (OR 1.7, 95%CI 1.2 to 5.9). MAIS spine was also predictive for the development of anxiety (OR 1.4, 95%CI 1.1 to 5.4, p = 0.0456). Non-injury related risk factors for depression include additional insults (OR 6.8, 95%CI 5.3 to 11.7, p = 0.0146); risk factors for the development of anxiety include need for psychiatric treatment after injury (OR 2.6, 95%CI 2.2 to 11.8, p < 0.001).</p> <p class="CxSpMiddle"><b>Conclusion</b></p> <p>More than half of polytrauma patients developed psychiatric complications. Risk factors include injuries to the central nervous system, additional psychiatric insults, and the need of psychiatric treatment.</p>
Prevalence, injury-, and non-injury-related predictors of anxiety and depression in polytrauma patients – A 20 year follow-up study
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
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OpenNeuro
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