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1,812 results for “dissection”
Data from: Dissecting the phenotypic components of crop plant growth and drought responses based on high-throughput image analysis
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Data from: Dissecting the paleocontinental and paleoenvironmental dynamics of the Great Ordovician Biodiversification
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Data from: Dissection of signaling modalities and courtship timing reveals a novel signal in Drosophila saltans courtship
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Data from: Outcomes after ischemic stroke caused by intracranial atherosclerosis versus dissection
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Quantitative dissection of transcription in development yields evidence for transcription factor-driven chromatin accessibility
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Ingested Nano- and Microplastic Particle Lengths and Surface Areas, dissected from salp guts, analyzed with Epifluorescence microscopy, collected aboard multiple cruises SEAPLEX in 2009, SKrillEx I in 2014, and SKrillEx II in 2015.
Salps were collected on SKrillEx I and II during nightly transects in 202-μm mesh bongo tows, towed to approximately 200 m depth, and samples were preserved in 5% formaldehyde buffered with sodium tetraborate. We also used zooplankton samples collected on the August 2009 SEAPLEX cruise, where samples were collected using a manta net, 333-μm mesh, towed for 15 minutes at the surface, with samples preserved in 5% formaldehyde buffered with sodium tetraborate. Salps were identified to species, life history phase (oozooid or blastozooid), and measured for zooid length. The length of the stomach was measured, noted for degree of fullness, and dissected from each salp. Dissected salp stomachs were cut in half and placed in 15 mL of Milli-Q water for at least 24 hours to soften and release gut contents. The contents were then vacuum-filtered onto 5-μm pore polycarbonate filters with an additional 70 mL of Milli-Q water to aid in filtration. Those filters were analyzed with modified epifluoresecence microscopy techniques for microplastic particles. All microplastic particles were analyzed for plastic shape, length, surface area, and fluorescence.
Dissecting transcriptional responses of nucleolin mutants to red light stimulation and darkness in ground reference conditions
Understanding plant adaptive responses to the space environment is a requisite for enabling space farming. Spaceflight produce deleterious effects on plant cells particularly affecting ribosome biogenesis a complex stress-sensitive process coordinated with cell division and differentiation known to be activated by red light. Here we have used mutants from the two nucleolin genes in Arabidopsis (NUC1 and NUC2) encoding the main regulator of the ribosome biogenesis in the nucleolus in order to better understand their role in adaptive response mechanisms to stress. Thus we show that nucleolin stress-related gene NUC2 can compensate the environmental stress provided by darkness in nuc1 plants while nuc2 plants are not able to provide a complete response to red light. These ground control findings as part of the ESA/NASA Seedling Growth spaceflight experiments will determine the basis for the identification of a genetic background enabling an adaptive advantage for plants in future space experiments.
Genetic Dissection of the Spaceflight Transcriptome Responses in Plants: are some responses unnecessary?
Experimentation on the International Space Station has reached the stage where repeated and nuanced transcriptome studies are beginning to illuminate the structural and metabolic differences between plants grown in space compared to plants on the Earth. Genes that are important in setting up the spaceflight responses are being identified; their role in spaceflight physiological adaptation are increasingly understood and the fact that different genotypes adapt differently is recognized. However the basic question of whether these spaceflight responses are required for survival has yet to be posed and the fundamental notion that spaceflight responses may be non-adaptive has yet to be explored. Therefore the experiments presented here were designed to ask if portions of the plant spaceflight response can be genetically removed without causing loss of spaceflight survival and without causing increased stress responses. The CARA experiment compared the spaceflight transcriptome responses of two Arabidopsis ecotypes Col-0 and WS as well as that of a PhyD mutant of Col-0. When grown with the ambient light of the ISS phyD displayed a significantly reduced spaceflight transcriptome response compared to Col-0 suggesting that altering the activity of a single gene can actually improve spaceflight adaptation by reducing the transcriptome cost of physiological adaptation. The WS genotype showed an even simpler spaceflight transcriptome response in the ambient light of the ISS more broadly indicating that the plant genotype can be manipulated to reduce the transcriptome cost of plant physiological adaptation to spaceflight and suggesting that genetic manipulation might further reduce or perhaps eliminate the metabolic cost of spaceflight adaptation. When plants were germinated and then left in the dark on the ISS the WS genotype actually mounted a larger transcriptome response than Col-0 suggesting that the in-space light environment affects physiological adaptation which further implies that manipulating the local habitat can also substantially impact the metabolic cost of spaceflight adaptation.
Comprehensive dissection of cis-regulatory elements in a 2.8 Mb topologically associated domain in six human cancers
GEO Series GSE278245. Homo sapiens. 21 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other.
Dissection of nucleosome remodeling at cis-regulatory elements in stimulated macrophages
GEO Series GSE119693. Mus musculus. 60 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Other.
A functional genomics process for systematic dissection and mutation-specific target discovery in breast cancer PIK3CA hotspot mutations [CRISPR KO Screen Data]
GEO Series GSE248041. Homo sapiens. 6 samples. Type: Other.
Identification of mRNAs and lincRNAs associated with lung cancer progression using next-generation RNA sequencing from laser micro-dissected archival FFPE tissue specimens
GEO Series GSE52248. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Tagger–a Swiss army knife for multiomics to dissect cell type-specific mechanisms of gene expression in mice [Ago-Tag-sRNA-seq]
GEO Series GSE123418. Mus musculus. 21 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Genetic Deletion of Socs3 in Smooth Muscle Cells Ameliorates Aortic Dissection in Mice
GEO Series GSE147078. Mus musculus. 12 samples. Type: Expression profiling by array.
Deep-Red and Ultrafast Photocatalytic Proximity Labeling Empowered in situ Dissection of Tumor-Immune Interactions in Primary Tissues
GEO Series GSE288148. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence
GEO Series GSE19899. Homo sapiens. 50 samples. Type: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing.
A systematic dissection of the epigenomic heterogeneity of lung adenocarcinoma reveals two different subclasses with distinct prognosis and core regulatory networks
GEO Series GSE150977. Homo sapiens. 92 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Dissection of Richter’s syndrome pathogenesis and treatment through multiplexed CRISPR-based mouse models
GEO Series GSE186137. Mus; Mus musculus. 35 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
ChIP-chip from dissected Drosophila egg chambers using antibody recognizing RNAPII
GEO Series GSE29518. Drosophila melanogaster. 1 samples. Type: Genome binding/occupancy profiling by genome tiling array.
Dissection of a super-enhancer in vivo (Capture-C)
GEO Series GSE78803. Mus musculus. 15 samples. Type: Other.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.