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ShareScore release 0.9.0
Dataset results
814 results for “pancreatic adenocarcinoma”
Characterization of exosomes from highly metastatic pancreatic adenocarcinoma line: ASML and a CD44v kd of ASML based on their miRNA content
GEO Series GSE34738. Rattus norvegicus; JC polyomavirus; Murid gammaherpesvirus 4; Betapolyomavirus hominis; Human gammaherpesvirus 8; Homo sapiens; Mus musculus; Human betaherpesvirus 5; Murid betaherpesvirus 1; Human immunodeficiency virus 1; Human alphaherpesvirus 1; human gammaherpesvirus 4; Betapolyomavirus macacae. 8 samples. Type: Non-coding RNA profiling by array.
microRNA screening in human pancreatic adenocarcinoma
GEO Series GSE74574. Homo sapiens; synthetic construct. 20 samples. Type: Non-coding RNA profiling by array.
Expression data from 2 cohorts of human pancreatic ductal adenocarcinoma (PDAC) tumors
GEO Series GSE89997. Homo sapiens. 30 samples. Type: Expression profiling by array.
Transcriptional effects of CTGF inhibition and gemcitabine in the KPC mouse model of pancreatic ductal adenocarcinoma
GEO Series GSE46203. Mus musculus. 24 samples. Type: Expression profiling by array.
ChIP-Chip tiling array for CTCF and Rad21 in mouse β-TC3 cells (pancreatic insulinoma) MV+ (lens epithelium) and RAG cells (renal adenocarcinoma) over panel of genes including Pax6, Sox2, Otx2, Sox9.
GEO Series GSE119658. Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by genome tiling array.
Digital spatial profiling of pancreatic ductal adenocarcinoma, acinar ductal metaplasia and adjacent normal pancreas tissue
GEO Series GSE208536. Homo sapiens. 48 samples. Type: Expression profiling by high throughput sequencing.
Cellular states associated with metastatic organotropism and survival in patients with pancreatic ductal adenocarcinoma
GEO Series GSE253430. Homo sapiens. 17 samples. Type: Other.
Blood-Based microRNA Biomarker Signature of Early-Stage Pancreatic Ductal Adenocarcinoma with Lead-Time Trajectory in Pre-Diagnostic Samples
GEO Series GSE259327. Homo sapiens. 299 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Expression data from pancreatic ductal adenocarcinoma (PDAC) cell lines AsPC1, BxPC3 and their cisplatin-resistant derivatives AsPC1-R and BxPC3-R
GEO Series GSE73978. Homo sapiens. 12 samples. Type: Expression profiling by array.
Expression data for Rab27a knockdown in the KPC 4662 pancreatic ductal adenocarcinoma cell line
GEO Series GSE148439. Mus musculus. 5 samples. Type: Expression profiling by array.
Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma impair CD8+ T cell activation and responsiveness to immunotherapy in mice
GEO Series GSE235246. Homo sapiens; Mus musculus. 38 samples. Type: Expression profiling by high throughput sequencing.
Expression data from human pancreatic ductal adenocarcinomas by stroma types
GEO Series GSE157353. Homo sapiens. 20 samples. Type: Expression profiling by array.
TP63-mediated enhancer reprogramming drives the squamous subtype of pancreatic ductal adenocarcinoma
GEO Series GSE115463. Mus musculus; Homo sapiens. 92 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Efficacy of GV1001 with gemcitabine/capecitabine in previously untreated patients with advanced pancreatic ductal adenocarcinoma having high serum eotaxin levels (KG4/2015): an open-label, randomized,
GEO Series GSE212575. Homo sapiens. 73 samples. Type: Protein profiling by protein array.
Endocrine-exocrine signaling in obesity-driven pancreatic ductal adenocarcinoma
GEO Series GSE131714. Mus musculus. 32 samples. Type: Expression profiling by high throughput sequencing.
PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance [ChIP-seq batch3]
GEO Series GSE91055. Mus musculus. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance [ChIP-seq batch1]
GEO Series GSE91053. Mus musculus. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Mechanism of Enhancing Chemotherapy Efficacy in Pancreatic Ductal Adenocarcinoma with Paricalcitol and Hydroxychloroquine: A Single Cell RNA Sequencing - Part1
<p><span>Pancreatic ductal adenocarcinoma (PDAC) boasts a dismal five-year survival rate of less than 15%, mainly due to therapy resistance. Recent studies have highlighted hydroxychloroquine (H) and paricalcitol (P), reducing stromal density and enhancing PDAC sensitivity to chemotherapy. This investigation aimed to elucidate the molecular impacts of combining H and P, focusing on their ability to sensitize PDAC to chemotherapy. <em>In vitro</em> and <em>in vivo</em> experiments demonstrated that the HP combination significantly (p<0.001) enhanced gemcitabine (G) effects, validated in orthotopic mouse models and patient-derived xenografts (PDX). Mechanistically, GPH induced cell death via the vitamin D receptor pathway upregulated autophagy and ER stress-related transcripts and suppressed mTOR signaling. Single-cell (sc) RNAseq analyses showed GPH increased quiescent cancer associated fibroblasts and reduced autophagy related transcripts. GPH treatment modulated T-cell populations favoring antitumor immunity. Findings from clinical trial patient biopsies underscored these effects, highlighting GPH's potential as a therapeutic adjunct in PDAC management (NCT04524702).</span></p>
Pancreatic Ductal Adenocarcinoma Spatial Transcriptomics
Open the record for dataset details and reuse information.
The Effect of Albumin Value, HALP Score, and LCR Value on Predicting Survival and Recurrence in Patients With Pancreatic Adenocarcinoma
ClinicalTrials.gov study NCT06553040. IPD Sharing: Not stated. Countries: 0. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.