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897 results for “Therapeutic targets”

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geo20/100

Phase separation of RXRγ drives tumor chemoresistance and represents a therapeutic target for small cell lung cancer

GEO Series GSE269090. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenDec 2024View details →
geo20/100

Alveolar Soft Part Sarcoma is driven by ASPSCR1::TFE3-dependent and therapeutically targetable transcriptional programs [ATAC-Seq]

GEO Series GSE255962. Homo sapiens. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenApr 2024View details →
geo20/100

RNA N6-methyladenosine methyltransferase METTL3 drives NAFLD-HCC and is a therapeutic target for boosting immunotherapy

GEO Series GSE233808. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.

openGEO-OpenAug 2023View details →
geo20/100

Therapeutic targeting of KDM1A/LSD1 in Ewing sarcoma engages the ER-stress response

GEO Series GSE98787. Homo sapiens. 44 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2019View details →
geo20/100

RNA-seq dataset for Identifying Novel Therapeutic Targets by Combining Transcriptional Data with Ordinal Clinical Measurements

GEO Series GSE98739. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2017View details →
geo20/100

Transcriptome analysis of desmoplastic small round cell tumors identifies actionable therapeutic targets: a report from the Children's Oncology Group

GEO Series GSE156277. Homo sapiens. 9 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenAug 2020View details →
geo20/100

A Novel Pro-Survival Function of Cyclin-D1 Underlies Its Oncogenic Role and Potential as a Therapeutic Target in Human and Murine Mantle Cell Lymphoma

GEO Series GSE25613. Homo sapiens. 20 samples. Type: Expression profiling by array.

openGEO-OpenJul 2011View details →
geo20/100

CD73 as a therapeutic target of pancreatic neuroendocrine tumor stem cells

GEO Series GSE62079. Homo sapiens. 2 samples. Type: Expression profiling by array.

openGEO-OpenMay 2016View details →
geo20/100

Multiomic Profile Integration Reveals Early Signatures of Amyotrophic Lateral Sclerosis and Suggests the MAPK Pathway as a Therapeutic Target

GEO Series GSE234246. Mus musculus. 158 samples. Type: Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing.

openGEO-OpenApr 2024View details →
geo20/100

Therapeutic targeting of Chronic Kidney Disease-associated DAMPs differentially contributing to vascular pathology. [atherosclerosis AAN+PaqusTLR2 blood]

GEO Series GSE236193. Mus musculus. 4 samples. Type: Expression profiling by RT-PCR.

openGEO-OpenSep 2023View details →
geo20/100

Gene Body Methylation Directly Increases Gene Expression and is a Therapeutic Target for Genes Upregulated in Cancer

GEO Series GSE51815. Homo sapiens. 40 samples. Type: Expression profiling by array; Methylation profiling by array.

openGEO-OpenAug 2014View details →
geo20/100

RNA N6-methyladenosine methyltransferase METTL3 drives NAFLD-HCC and is a therapeutic target for boosting immunotherapy [m6A-seq]

GEO Series GSE233807. Homo sapiens. 8 samples. Type: Methylation profiling by high throughput sequencing.

openGEO-OpenAug 2023View details →
geo20/100

Therapeutic Targeting of BET Bromodomain Proteins in Castration-Resistant Prostate Cancer (ChIP-Seq)

GEO Series GSE55062. Homo sapiens. 35 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenApr 2014View details →
geo20/100

Patient-Specific Pharmacogenomics demonstrates xCT as Predictive Therapeutic Target in Colon Cancer with Possible Implications in Tumor Connectivity

GEO Series GSE305337. Homo sapiens. 73 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2025View details →
geo20/100

Targeting transcription-replication conflicts is an effective therapeutic principle for MYCN-driven neuroblastoma [ChIP-seq GB]

GEO Series GSE144283. Homo sapiens. 15 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenNov 2020View details →
geo16/100

Genetic characterization and therapeutic targeting of MYC rearranged T-cell acute lymphoblastic leukemia

GEO Series GSE106939. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.

openGEO-OpenJul 2018View details →
geo16/100

Soluble adenylyl cyclase induces type 17 inflammation and is a potential therapeutic target in psoriasis

GEO Series GSE175470. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2021View details →
geo16/100

Unveiling Immune Metabolic Mechanisms in Bladder Cancer: Spatial Profiling Identifies ZFP36 as a Therapeutic Target

GEO Series GSE285715. Homo sapiens. 6 samples. Type: Other.

openGEO-OpenJul 2025View details →
geo16/100

Lamin C supplementation as therapeutic target for treatment of Lmna Dilated Cardiomyopathy (DCM) and risk of Lamin A toxicity

GEO Series GSE240745. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2024View details →
geo16/100

Analysis of Gene Expression Heterogeneity Reveals Therapeutic Targets and Novel Regulators of Metastasis

GEO Series GSE220671. Homo sapiens. 13 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2025View details →

ScienceDex guides

Understand access before you commit

These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record