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783
datasets available to search
ShareScore release 0.7.1
Dataset results
783 results for “lung adenocarcinoma”
ARID1A Loss Promotes Lung Adenocarcinoma by Remodeling Chromatin Accessibility and Activating Glycolytic Reprogramming
GEO Series GSE164810. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Expression of genes affected by ectopic expression of FOXA2 in H441 human lung adenocarcinoma cells
GEO Series GSE210083. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
GSE1 promotes the proliferation and migration of lung adenocarcinoma cells by downregulating KLF6 expression
GEO Series GSE242323. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome of tumor biopsy sample of patient with non-small-cell lung adenocarcinoma, ALK rearrangement positive
GEO Series GSE133605. Homo sapiens. 1 samples. Type: Expression profiling by array; Third-party reanalysis.
RNF6 enhances chemo-resistance by transcriptionally activating PCNA expression and attenuating DNA damage in lung adenocarcinoma.
GEO Series GSE189299. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Dataset related to article "Invasive IPMN relapse later and more often in lungs in comparison to pancreatic ductal adenocarcinoma"
<p>This record contains data related to article “Invasive IPMN relapse later and more often in lungs in comparison to pancreatic ductal adenocarcinoma”</p> <p><strong>Background: </strong> The different oncological outcomes of invasive intraductal papillary mucinous neoplasm (I-IPMN) and pancreatic ductal adenocarcinoma (PDAC) are debated. This study aimed to compare disease recurrence patterns and histopathological characteristics in patients with resected I-IPMN and PDAC.</p> <p><strong>Methods: </strong> Consecutive patients undergoing surgical resection for stage I-III I-IPMN or PDAC between 2010 and 2016 were retrospectively analyzed. Patients treated with neoadjuvant therapy or resected for Tis neoplasia were excluded. All surgical specimens were re-staged according to AJCC-8th-edition.</p> <p><strong>Results: </strong> A total of 330 patients were included, of whom 43 had I-IPMN and 287 had PDAC. Median follow-up time was 26.7 (1.3-92.3) months and estimated median disease-free survival (DFS) was 60.3 months (47.2-73.4) for I-IPMN and 23.8 (19.3-28.2) months for PDAC (p < 0.001). During follow-up, 32.6% of I-IPMN and 67.9% of PDAC patients experienced recurrence (p < 0.001). The sites of first recurrence were the lungs (38.5% vs 13.1%, p = 0.027), liver (28.6% vs 45.0%, p = 0.180) and local (15.4% vs 36.6%, p = 0.101) for I-IPMN and PDAC, respectively. At multivariate analysis, I-IPMN histology remained an independent predictive factor for longer DFS (OR 0.528, CI 95% 0.278-1.000, p = 0.050), regardless of stage or adjuvant chemotherapy. I-IPMN and PDAC differed in rates of neuroinvasion (51.2% vs 97.2%) and positive lymph node status (N+) (46.5% vs 82.7%), especially in patients with lower T status.</p> <p><strong>Conclusion: </strong> I-IPMN showed a different recurrence pattern compared to PDAC, with a higher lung tropism, and longer DFS. This different biological behavior is associated with lower rates of neuroinvasion and nodal involvement, especially in early-stage disease.</p>
HP1γ/CBX3 Promotes Lung Adenocarcinoma by Activating Rho GTPases Signaling Pathway
GEO Series GSE173858. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Aberrant Expression Profile of Circular RNAs in Human Lung Adenocarcinoma by Microarray Analysis
GEO Series GSE161348. Homo sapiens. 6 samples. Type: Non-coding RNA profiling by array.
Differentially expressed genes between the bone metastatic subpopulations and lung metastatic subpopulations of lung adenocarcinoma
GEO Series GSE249364. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.
Alveolar differentiation drives resistance to KRAS inhibition in lung adenocarcinoma
GEO Series GSE246482. Mus musculus; Homo sapiens. 33 samples. Type: Expression profiling by high throughput sequencing.
MicroRNA and mRNA regulatory network in ALK-rearranged lung adenocarcinoma [miRNA]
GEO Series GSE128310. Homo sapiens. 77 samples. Type: Non-coding RNA profiling by array.
Single-cell transcriptome reveals drug-resistance signature and immunosuppressive microenvironment in lung adenocarcinoma harboring EGFR mutation
GEO Series GSE253718. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Gramd2+ alveolar type I cells can give rise to Kras-induced lung adenocarcinoma
GEO Series GSE215858. Mus musculus. 8 samples. Type: Other.
Single-cell transcriptomics of precursor lung adenocarcinoma reveals intratumoral heterogeneity and shifting immune network
GEO Series GSE164789. Homo sapiens. 78 samples. Type: Expression profiling by high throughput sequencing.
A novel oncomicropeptide encoded by DSP-AS1 exhibits proneoplastic properties in lung adenocarcinoma by facilitating YTHDF1-induced translation initiation through mediation of mRNA circularization
GEO Series GSE249133. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing; Other.
ADAM9 Up-regulates N-Cadherin via MiR-218 Suppression in Lung Adenocarcinoma Cells [miRNA]
GEO Series GSE51833. Homo sapiens. 3 samples. Type: Non-coding RNA profiling by array.
cAMP response element-binding protein mediates immune-evasion of KRAS-mutant lung adenocarcinomas
GEO Series GSE156513. Mus musculus. 2 samples. Type: Expression profiling by array.
Long non-coding RNA CAR10 promotes lung adenocarcinoma metastasis via miR-203/30/SNAI axis
GEO Series GSE121397. Homo sapiens. 9 samples. Type: Expression profiling by array.
TTF1 and TKTL1 mRNAs in Extracellular Vesicles as a Blood Biomarker for Lung Adenocarcinoma
GEO Series GSE71661. Homo sapiens. 57 samples. Type: Non-coding RNA profiling by high throughput sequencing.
APE1 regulates the transcription of urea cycle genes through stabilizing DNA G-quadruplexes in lung adenocarcinoma [CUT&Tag]
GEO Series GSE245167. Homo sapiens. 14 samples. Type: Other; Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.