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Dataset results
195 results for “Adolescent idiopathic scoliosis”
Reliability and Validity of the Adolescent Idiopathic Scoliosis - Truncal Anterior Asymmetry Scoliosis Questionnaire (TAASQ)
ClinicalTrials.gov study NCT07276165. IPD Sharing: NO. Countries: 1. Publications: 4.
Raw data for the article: Investigating the Differential Circulating microRNA Expression in Adolescent Females with Severe Idiopathic Scoliosis: A Proof-of-Concept Observational Clinical Study
<p>Adolescent Idiopathic Scoliosis (AIS) is the most common form of three-dimensional spinal disorder in adolescents between the ages of 10 and 18 years of age, most commonly diagnosed in young women when severe disease occurs. Patients with AIS are characterized by abnormal skeletal growth and reduced bone mineral density. The etiology of AIS is thought to be multifactorial, involving both environmental and genetic factors, but to date, it is still unknown. Therefore, it is crucial to further investigate the molecular pathogenesis of AIS and to identify biomarkers useful for predicting curve progression. In this perspective, the relative abundance of a panel of microRNAs (miRNAs) was analyzed in the plasma of 20 AIS patients and 10 healthy controls (HC). The data revealed a significant group of circulating miRNAs dysregulated in AIS patients compared to HC. Further bioinformatic analyses evidenced a more restricted expression of some miRNAs exclusively in severe AIS females. These include some members of the miR-30 family, which are considered promising regulators for treating bone diseases. We demonstrated circulating extracellular vesicles (EVs) from severe AIS females contained miR-30 family members and decreased the osteogenic differentiation of mesenchymal stem cells. Proteomic analysis of EVs highlighted the expression of proteins associated with orthopedic disease. This study provides preliminary evidence of a miRNAs signature potentially associated with severe female AIS and suggests the corresponding vesicular component may affect cellular mechanisms crucial in AIS, opening the scenario for in-depth studies on prognostic differences related to gender and grade.</p>
Erector Spinae Plane Blocks for Adolescent Idiopathic Scoliosis
ClinicalTrials.gov study NCT04500613. IPD Sharing: YES. Countries: 1. Publications: 0.
Orthopaedic Manipulation in Treatment of Adolescent Idiopathic Scoliosis
ClinicalTrials.gov study NCT05639023. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Myofascial and Articular Treatment of Adolescent Idiopathic Scoliosis
ClinicalTrials.gov study NCT05423509. IPD Sharing: NO. Countries: 1. Publications: 0.
Posterior Spinal Fusion With Pedicle Screws vs. Anterior Vertebral Body Tethering in Adolescent Idiopathic Scoliosis
ClinicalTrials.gov study NCT04590807. IPD Sharing: NO. Countries: 0. Publications: 3.
The Effect of Vertebral Body Tethering on Lumbar Paraspinal Muscle Cross-Section Area in Adolescent Idiopathic Scoliosis
ClinicalTrials.gov study NCT05347056. IPD Sharing: UNDECIDED. Countries: 0. Publications: 4.
Vitamin D Levels in Adolescent Idiopathic Scoliosis
ClinicalTrials.gov study NCT03820895. IPD Sharing: UNDECIDED. Countries: 0. Publications: 9.
Use of Ultrasonic Bone Scalpel in Adolescent Idiopathic Scoliosis
ClinicalTrials.gov study NCT02781324. IPD Sharing: NO. Countries: 1. Publications: 0.
Evaluation of a Chatbot-Delivered Structured Psychological Intervention for Teenagers With Adolescent Idiopathic Scoliosis
ClinicalTrials.gov study NCT06698952. IPD Sharing: NO. Countries: 0. Publications: 1.
This Cross-sectional Study Investigates the Relationship Between Different Curve Patterns in Adolescent Idiopathic Scoliosis (AIS) and the Distribution of Foot Pressure. It Aims to Determine Whether C
ClinicalTrials.gov study NCT07172048. IPD Sharing: YES. Countries: 1. Publications: 0.
Compliance to Treatment in Adolescent Girls With Idiopathic Scoliosis: is it Associated With Perception of Appearance, Self-esteem, and Quality of Life?
ClinicalTrials.gov study NCT06023992. IPD Sharing: NO. Countries: 0. Publications: 11.
Genome-Wide Profiling of Circulating MicroRNAs in Adolescent Idiopathic Scoliosis
GEO Series GSE286204. Homo sapiens. 112 samples. Type: Non-coding RNA profiling by array.
Dataset from "Sports activity reduces the risk of progression and bracing: an observational study of 511 Risser 0–2 adolescents with idiopathic scoliosis"
<p>Dataset from a still non-published study titled "Sports activity reduces the risk of progression and bracing: an observational study of 511 Risser 0–2 adolescents with idiopathic scoliosis"</p>
Effectiveness of Acceptance and Commitment Therapy Versus Active Controls in Improving Psychological Functions of Parents and Children With Adolescent Idiopathic Scoliosis: A Randomized Controlled Tri
ClinicalTrials.gov study NCT05919459. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Investigating the Potential Psychological Impact of Early Screening and Long-term Monitoring for Adolescent Idiopathic Scoliosis Among Patients and Caregivers
ClinicalTrials.gov study NCT05152329. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Ergonomic Brace Wear for Adolescent Idiopathic Scoliosis
ClinicalTrials.gov study NCT03617120. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Phase IV Comparing Rods of Yield Strengths to Correct Adolescent Idiopathic Scoliosis.
ClinicalTrials.gov study NCT00768313. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Short-term Effects of the Simultaneous Use of Two Physiotherapeutic Methods in the Treatment of Adolescent Idiopathic Scoliosis - Pilot Study
ClinicalTrials.gov study NCT01250860. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Clinical Effectiveness of Intervertebral Disc Release in Treating Lenke 5 Adolescent Idiopathic Scoliosis
ClinicalTrials.gov study NCT06279468. IPD Sharing: NO. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.