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595 results for “Aspergillus”
Fig. 2 in Prenylated phenylbutyrolactones from cultures of a marine sponge-associated fungus Aspergillus flavipes KUFA1152
Fig. 2. Model of the most abundant conformation of 7 (B3LYP/6-31G(d) lowest energy conformer) in its (2S) configuration, as assigned by ECD. The line box marks the fragment whose conformation was set to unchange, although free to be optimized by the several methods used.
Fig. 3 in Pyrazinopyrimidine alkaloids from a mangrove-derived fungus Aspergillus versicolor HDN11-84
Fig. 3. DP4+ probability analyses for candidates diastereomers of 1 and 2 (Gibbs free energies at the PCM/B3LYP/6-31+G (d,p) level were used for the analysis).
Fig. 5 in Transformation of 15-ene steviol by Aspergillus niger, Cunninghamella bainieri, and Mortierella isabellina
Fig. 5. Simultaneous analysis of cytokine profiles produced in cultured medium of THP-1 cells with or without lipopolysaccharide (LPS) ± 10 μM of compounds, detected with a human cytokine antibody array (Abcam, ab133997). A) Representative images. B) Quantitative data.
Fig. 6 in Transformation of 15-ene steviol by Aspergillus niger, Cunninghamella bainieri, and Mortierella isabellina
Fig. 6. Molecular docking mode of I) compounds 2, and 10–12 with glucocorticoid receptor (GR)-binding sites: a), b), c), and d) are respective binding modes of compounds 2, 10, 11, and 12 at their active site of GR; e), f), g), and h) are respective 2D ligand interaction diagrams of compounds 2, 10, 11, and 12; II) dexamethasone with GR binding. The green dashed line represents hydrogen bond and amino acid interactions; the tan amino acids represent van der Waals interactions; the pink dashed line represents alkyl and pi-alkyl interactions. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 5 in Asperanstinoids A-E: Undescribed 3,5-dimethylorsellinic acid-based meroterpenoids from Aspergillus calidoustus
Fig. 5. Experimental ECD curves of compounds 3 and 5 in MeOH and their calculated ECD spectra at the PBE0/def2-TZVP level.
Fig. 2 in Asporychalasin, a bioactive cytochalasan with an unprecedented 6/6/11 skeleton from the Red Sea sediment Aspergillus oryzae
Fig. 2. Left: 2D NMR COSY (red bold) and HMBC (blue arrows) correlations detected for asporychalasin. Right: Key NOESY correlations (red arrows) for asporychalasin. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 4 in Asporychalasin, a bioactive cytochalasan with an unprecedented 6/6/11 skeleton from the Red Sea sediment Aspergillus oryzae
Fig. 4. Experimental ECD curve of asporychalasin (red) and calculated ECD curves for 1a (black) and its enantiomer (green). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 3. The four possible diastereomers 1a-1d in Asporychalasin, a bioactive cytochalasan with an unprecedented 6/6/11 skeleton from the Red Sea sediment Aspergillus oryzae
Fig. 3. The four possible diastereomers 1a-1d and the most populated conformer for each diastereomer.
Aspergillus flavus germination, ex vivo
<p>Time-lapse imaging showing intrastromal germination of Aspergillus flavus conidia following intrastromal injection into a porcine cornea. Conidial germination and hyphal elongation can be observed by sixteen hours post-inoculation. </p>
Fig. 3 in Azaphilones with protein tyrosine phosphatase inhibitory activity isolated from the fungus Aspergillus deflectus
Fig. 3. Graph of 13C-Dp4+ probabilities obtained by correlating the calculated and experimental 13C NMR data of 4 (1: 2′S-isomer; 2: 2′R-isomer).
Fig. 1 in 1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity
Fig. 1. Structures of specialised metabolites isolated from the cultures of the marine sponge-associated fungus Aspergillus elegans KUFA0015.
Fig. 7 in 1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity
Fig. 7. Models of 6 representing the two lowest energy conformations of the central ring (groups G1, left, and G2, right) as well as the lowest energy transition state model TS for the conversion between G1 and G2. For correct 3D interpretation of these projections, consider the H-11 nuclei nearer to the observer and the methoxy groups farther from the observer.
Fig. 6 in 1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity
Fig. 6. Expansion and assignments of 1H NMR spectra of H-11 geminal nuclei, Ha and Hb, at two different temperatures, in DMSO‑d6, at 500 MHz. The measured scalar coupling constant of 5 Hz is within the typical range for geminal protons. Assignments refer to labels used in Fig. 7.
Fig. 7 in Characterization of diketopiperazine heterodimers as potential chemical markers for discrimination of two dominant black aspergilli, Aspergillus niger and Aspergillus tubingensis
Fig. 7. HPLC-DAD spectra of the crude extracts of A. niger (A) and A. tubingensis (B) cultivated in PDB medium. (Chromatographic conditions: Column: SunFire® C18, 250 mm × 4.60 mm, 5 μm; Mobile phase: MeCN–H2O, 0–30 min, 30%–100% MeCN; Flow rate: 1 mL/min; UV detection: 235 nm).
Fig. 5 in Characterization of diketopiperazine heterodimers as potential chemical markers for discrimination of two dominant black aspergilli, Aspergillus niger and Aspergillus tubingensis
Fig. 5. Culture and morphological characteristics of Aspergillus niger (A) and A. tubingensis (D), colonies on PDA media; Conidia and conidiophores heads of A. niger (B–C) and A. tubingensis (E–F).
Fig. 6 in Characterization of diketopiperazine heterodimers as potential chemical markers for discrimination of two dominant black aspergilli, Aspergillus niger and Aspergillus tubingensis
Fig. 6. Neighbor-joining (NJ) trees based on the 18S (A), 26S (B) and ITS rDNA regions (C). HQM289 and TB3291 represent A. niger and A. tubingensis, respectively. NJ bootstrap values were estimated and marked above the branches.
Data from: Phase-dependent differential in vitro and ex vivo susceptibility of Aspergillus flavus and Fusarium keratoplasticum to azole antifungals
<p>Fungal keratitis (FK) is an invasive infection of the cornea primarily associated with <em>Aspergillus</em> and <em>Fusarium</em> species. FK is treated empirically with a limited selection of topical antifungals with varying levels of success. Though clinical infections are typically characterized by a dense network of mature mycelium, traditional models used to test antifungal susceptibility of FK isolates exclusively evaluate susceptibility in fungal cultures derived from asexual spores known as conidia. The purpose of this study was to characterize differences in fungal response when topical antifungal treatment is initiated at progressive phases of fungal development. We compared efficacy of voriconazole and luliconazole against <em>in vitro</em> cultures of <em>A. flavus</em> and <em>F. keratoplasticum</em> at 0, 24, and 48 h of fungal development. Data from this assay is included here, reported as end-point absorbance values. A porcine cadaver corneal model was used to compare antifungal efficacy of voriconazole and luliconazole in <em>ex vivo</em> tissue cultures of <em>A. flavus</em> and <em>F. keratoplasticum</em> at 0, 24, and 48 h of fungal development. Data from this assay may be found here, reported as pixel counts of the determined area.</p>
Risk of Aspergillus Infection in Patients With Chronic Lung Disease
ClinicalTrials.gov study NCT06379568. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
A New Posaconazole Dosing Regimen for Paediatric Patients With Cystic Fibrosis and Aspergillus Infection
ClinicalTrials.gov study NCT04966234. IPD Sharing: YES. Countries: 11. Publications: 12.
A Clinical Study of MK0991 (Caspofungin) in Japanese Patients With Deep-seated Candida or Aspergillus Infections (0991-062)(COMPLETED)
ClinicalTrials.gov study NCT00717860. IPD Sharing: YES. Countries: 0. Publications: 1.
ScienceDex guides
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.