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77 results for “Drosophila simulans”
Data from: Variable post-zygotic isolation in Drosophila melanogaster/D. simulans hybrids
The study of hybrid inviability reveals cryptic divergence between the genetic interactions that maintain stable phenotypes in the pure species. We characterized the effects of natural variation on the penetrance of hybrid inviability phenotypes in crosses between Drosophila melanogaster and two species of the D. simulans subcomplex, D. simulans and D. sechellia. Using a panel of wild-caught lines, we studied the levels of genetic variance present in D. simulans and D. sechellia affecting prezygotic and post-zygotic isolation in hybridizations with D. melanogaster females. We observed extensive variability in the viability of hybrid individuals, dependent on the genotype of the parents, suggesting that intraspecific natural variation manifests directly in hybrid phenotypes. Furthermore, we found that genetic background significantly affects the penetrance of a well-studied determinant of hybrid inviability: the interaction between Hmrmel–Lhrsim. Our results suggest that hybrid inviability – and reproductive isolation generally – can be modified by polymorphisms at multiple loci segregating within the parental species. Just as the penetrance of most mutant phenotypes can be modified by the genetic background within the pure species, the penetrance of hybrid inviability phenotypes is highly influenced by the parental genotypes.
Data from: Fine-scale genetic analysis of species-specific female preference in Drosophila simulans
Behavioral differences are thought to be the first components to contribute to species isolation, yet the precise genetic basis of behavioral isolation remains poorly understood. Here, we used a combination of behavior assays and genetic mapping to provide the first refined map locating candidate genes for interspecific female preference isolating Drosophila simulans from D. melanogaster. First, we tested whether two genes identified as affecting D. melanogaster female intraspecific mate choice also affect interspecific mate choice; neither of these genes was found to contribute to species-specific female preference. Next, we used deficiency mapping to locate genes on the right arm of the third chromosome for species-specific female preference and identified five small significant regions that contain candidate genes contributing to behavioral isolation. All five regions were located in areas that would have low interspecific recombination, which mirrors the results of other behavioral isolation studies that used quantitative trait locus (QTL) mapping, but without the potential concern of bias towards regions of low recombination that QTL mapping may have. Since this model system may be refined to the individual gene level using the same methodology, this initial map we provide may potentially serve as a ready template for the identification and characterization of the first behavioral isolation genes.
Data from: Antagonistic responses to natural and sexual selection and the sex-specific evolution of cuticular hydrocarbons in Drosophila simulans
Natural and sexual selection are classically thought to oppose one another, and while there is evidence for this, direct experimental demonstrations of this antagonism are largely lacking. Here we assessed the effects of sexual and natural selection on the evolution of cuticular hydrocarbons (CHCs), a character subject to both modes of selection, in Drosophila simulans. Natural selection and sexual selection were manipulated in a fully factorial design, and after 27 generations of experimental evolution the responses of male and female CHCs were assessed. The effects of natural and sexual selection differed greatly across the sexes. The responses of female CHCs were generally small, but CHCs evolved predominantly in the direction of natural selection. For males, profiles evolved via sexual and natural selection, as well as through the interaction between the two, with some male CHC components only evolving in the direction of natural selection when sexual selection was relaxed. These results indicate sex-specific responses to selection, and that sexual and natural selection act antagonistically for at least some combinations of CHCs.
Detection of duplication polymorphisms in the Drosophila simulans genome
GEO Series GSE29260. Drosophila simulans; Drosophila melanogaster. 14 samples. Type: Genome variation profiling by genome tiling array.
Data from: Antagonistic responses to natural and sexual selection and the sex-specific evolution of cuticular hydrocarbons in Drosophila simulans
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Data from: Fine-scale genetic analysis of species-specific female preference in Drosophila simulans
Open the record for dataset details and reuse information.
Data from: Variable post-zygotic isolation in Drosophila melanogaster/D. simulans hybrids
Open the record for dataset details and reuse information.
Gene expression analysis of interspecific and intraspecific Y chromosome introgessions in Drosophila simulans
GEO Series GSE31907. Drosophila melanogaster; Drosophila simulans. 32 samples. Type: Expression profiling by array.
Drosophila simulans blue gut larvae vs. white prepupae
GEO Series GSE134. Drosophila melanogaster; Drosophila simulans. 4 samples. Type: Expression profiling by array.
Molecular insights into female hybrid sterility in interspecific crosses between Drosophila melanogaster and Drosophila simulans
GEO Series GSE263985. Drosophila melanogaster; Drosophila simulans; Drosophila melanogaster x Drosophila simulans. 12 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Drosophila pseudoobscura and Drosophila simulans small RNAs
GEO Series GSE13677. Drosophila pseudoobscura; Drosophila simulans. 3 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Developmental time-course study of Drosophila melanogaster, D. sechellia, D. simulans, and D. sim x D.s sec hybrids
GEO Series GSE17535. Drosophila melanogaster; Drosophila sechellia; Drosophila simulans; Drosophila sechellia x Drosophila simulans. 48 samples. Type: Expression profiling by array.
Fine scale genetic mapping of a Hybrid Male Sterility factor between Drosophila simulans and D. mauritiana
GEO Series GSE25339. Drosophila melanogaster. 10 samples. Type: Expression profiling by array.
Essential functions of RNA helicase Vasa in Drosophila spermatogenesis, from maintenance of germline stem cells to passage through meiosis between Drosophila melanogaster and Drosophila simulans [RNA-
GEO Series GSE269988. Drosophila melanogaster. 3 samples. Type: Expression profiling by high throughput sequencing.
Essential functions of RNA helicase Vasa in Drosophila spermatogenesis, from maintenance of germline stem cells to passage through meiosis between Drosophila melanogaster and Drosophila simulans [smRN
GEO Series GSE269987. Drosophila melanogaster. 6 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Regulatory divergence in Drosophila melanogaster and D. simulans: a genome-wide analysis of allele-specific expression
GEO Series GSE17453. Drosophila melanogaster; Drosophila sp. (in: flies); Drosophila simulans. 24 samples. Type: Expression profiling by genome tiling array.
Investigating the fruitless-directed molecular and circuit architecture of courtship behavior in Drosophila melanogaster, Drosophila simulans and their hybrids
GEO Series GSE304737. Drosophila melanogaster; Drosophila simulans. 7 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.