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321
datasets available to search
ShareScore release 0.9.0
Dataset results
321 results for “Drug response”
Ex Vivo Drug Response Evaluation for Next Generation Care of Brain Metastases
ClinicalTrials.gov study NCT06620380. IPD Sharing: UNDECIDED. Countries: 1. Publications: 3.
Variability of Sulfotransferase 1A1 Activity in Humans: an Approach to Improve Predictive Drug Response - Part I: Analysis of Intraindividual Variation in Healthy Adults
ClinicalTrials.gov study NCT03182595. IPD Sharing: NO. Countries: 1. Publications: 1.
A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment o
ClinicalTrials.gov study NCT00000796. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Modeling and Application of Triple Drug Response Surface Models
ClinicalTrials.gov study NCT03813875. IPD Sharing: NO. Countries: 1. Publications: 7.
Study of Hepatic Responses in Patients Receiving Direct-acting Anti-HCV Drugs
ClinicalTrials.gov study NCT02532907. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Application and Validation of Triple Drug Response Surface Models on Density Spectral Array in Clinical Anesthesia
ClinicalTrials.gov study NCT05525351. IPD Sharing: NO. Countries: 1. Publications: 8.
Data from: Impact of the Mass Drug Administration for malaria in response to the Ebola outbreak in Sierra Leone
Open the record for dataset details and reuse information.
Data from: Evolution of drug-tolerant nematode populations in response to density reduction
Resistance to xenobiotics remains a pressing issue in parasite treatment and global agriculture. Multiple factors may affect the evolution of resistance, including interactions between life-history traits and the strength of selection imposed by different drug-doses. We experimentally created replicate selection lines of free-living Caenorhabditis remanei exposed to Ivermectin at high and low doses to assess whether survivorship of lines selected in drug-treated environments increased, and if this varied with dose. Additionally, we maintained lines where mortality was imposed randomly to control for differences in density between drug-treatments and to distinguish between the evolutionary consequences of drug-treatment vs ecological processes due to changes in density-dependent feedback. After 10 generations we exposed all of the selected lines to high-dose, low-dose and drug-free environments to evaluate evolutionary changes in survivorship as well as any costs to adaptation. Both adult and juvenile survival was measured to explore relationships between life-history stage, selection regime and survival. Intriguingly, both drug-selected and random-mortality lines showed an increase in survivorship when challenged with Ivermectin; the magnitude of this increase varied with the intensity of selection and life-history stage. Our results suggest that interactions between density-dependent processes and life-history may mediate evolved changes in susceptibility to control measures.
Microwell-Based Flow Culture Increases Viability and Restores Drug Response in Prostate Cancer Spheroids
<p>Data files for main manuscript figures.</p>
Developmental Regulation of Proteins Responsible for Transforming Drugs in the Body
ClinicalTrials.gov study NCT00117715. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study of MabThera (Rituximab) in Participants With Rheumatoid Arthritis Who Have Had an Inadequate Response to Disease-Modifying Antirheumatic Drugs (DMARD) and/or Anti-Tumor Necrosis Factor (Anti-T
ClinicalTrials.gov study NCT00503425. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Disease-Modifying Antirheumatic Drugs (DMARD
ClinicalTrials.gov study NCT01235507. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study to Evaluate the Efficacy, Safety, and Drug Levels of Oral Ozanimod in Pediatric Participants With Moderately to Severely Active Crohn's Disease With an Inadequate Response to Conventional Ther
ClinicalTrials.gov study NCT05470985. IPD Sharing: Not stated. Countries: 9. Publications: 0.
A Study of Tocilizumab in Combination With Disease-Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Moderate to Severe Active Rheumatoid Arthritis With an Inadequate Response to DMARDs
ClinicalTrials.gov study NCT00996606. IPD Sharing: Not stated. Countries: 1. Publications: 0.
TORPEDO Study: A Study on Rapid Effect of Tocilizumab in Patients With Rheumatoid Arthritis With an Inadequate Response to Disease-Modifying Antirheumatic Drugs (DMARDs) or Anti-TNF
ClinicalTrials.gov study NCT00977106. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Individual Differences in Drug Response
ClinicalTrials.gov study NCT03809546. IPD Sharing: NO. Countries: 1. Publications: 0.
Effects of Dietary Conditions on Drug Response
ClinicalTrials.gov study NCT04315961. IPD Sharing: NO. Countries: 1. Publications: 0.
A Study To Evaluate The Safety And Effects On The Body Of An Investigational Drug Using An Endotoxin-Induced Inflammatory Response Model
ClinicalTrials.gov study NCT01965600. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study of Tocilizumab in Participants With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Non-Biological Disease-modifying Anti-rheumatic Drugs (DMARDs)
ClinicalTrials.gov study NCT01617005. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effects of Drugs on Responses to Brain and Emotional Processes
ClinicalTrials.gov study NCT04053036. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.