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849 results for “Lactation”
Greater lactate accumulation does not alter peripheral concentrations of key appetite-regulating neuropeptides - Supplementary Data
<p>The manuscript "Greater lactate accumulation does not alter peripheral concentrations of key appetite-regulating neuropeptides" has been submitted to the Journal of Applied Physiology and the following data are supplementary data for this manuscript. Upon acceptance this record will be updated with the manuscript and journal information.</p>
Data from: Trade-offs in lactation and milk intake by competing siblings in a fluctuating environment
Income breeders which forage without their offspring in attendance should adjust nursing frequency and the quantity and composition of milk to prevailing ecological conditions, and increase the quantity or quality of milk transferred if the frequency of nursing visits declines. When milk delivery to a litter is insufficient, sibling competition should skew milk consumption in favor of dominant litter members. We quantified milk nutritional composition and gross energy density, nursing bout durations, per capita milk transfer (kg), and milk transfer rate (g/min) per nursing bout in singletons and twins in a social carnivore, the spotted hyena. In our study population, the energetic cost of lactation is rank dependent and particularly high because large fluctuations in local prey abundance necessitate long-distance foraging, reducing nursing frequency and intensifying sibling competition, more frequently for low-ranking than high-ranking females. Females increased milk gross energy density, driven by fat content, and increased nursing bout durations as nursing frequency declined. Milk transfer increased as social status declined. Females below median rank also increased milk transfer as nursing frequency declined. Milk transfer was independent of nursing frequency in females above median rank and higher for singletons than cubs in twin litters. Dominant siblings achieved significantly higher amounts and rates of milk transfer than their paired subordinate littermates; this bias increased as sibling competition intensified. Our results show how the interplay between ecological and social constraints determines the quality and quantity of milk transferred, and how socially dominant siblings use aggression to skew milk intake in their favor.
Umbilical artery lactate levels and associated maternal and newborn characteristics at Mulago National Referral Hospital: A cross-sectional observational study
<p><b>Objective: </b>To determine the maternal and newborn characteristics associated with high umbilical artery lactate levels at Mulago National Referral Hospital.</p> <p><b>Design</b>: Cross-sectional observational study.</p> <p><b>Setting</b>: Department of Obstetrics and Gynecology at a national referral hospital located in the capital of Uganda, Kampala.</p> <p><b>Participants</b>: We randomly selected 720 pregnant mothers at term who presented in labour and their newborn babies.</p> <p><b>Primary outcome</b>: Umbilical artery lactate level.</p> <p><b>Results</b>: During the study, there were 579 vaginal deliveries (18 instrumental) and 141 caesarean sections which met the inclusion criteria. One hundred eighty seven neonates (187) had high arterial lactate levels. The following factors were associated with an increased likelihood of high lactate concentration<b>: </b>male<b> </b>sex (aOR = 1.71; 95%CI 1.16–2.54; <i>P<</i>0.05), primigravidity (aOR = 2.78; 95%CI 1.89-4.08; <i>P </i>< 0.001), Meconium stained liquor (MSL) (aOR = 5.85; 95%CI 4.08-8.47; P<0.001) and, Administration of oxytocin (aOR = 1.97; 95%CI 1.00-3.77; <i>P<</i>0.05).</p> <p><b>Conclusion</b>: About a fifth of the babies born in Mulago national referral hospital during the study period had high umbilical artery lactate. The maternal-fetal factors significantly associated with high umbilical artery lactate levels included: baby's sex, mother's gravidity, meconium stained amniotic fluid, and oxytocin administration during labour.</p>
A Method for Differentiating Sepsis and Septic Shock Based on Phenylalanine Hydroxylase and Lactate Dehydrogenase Activity
<p>The present method relates to improving the prognosis, diagnosis, and treatment of sepsis and septic shock. Despite the availability of advanced treatment, sepsis, and septic shock have the highest mortality in the intensive care unit (ICU). Theories suggested that hyperinflammation is a major characteristic of septic shock, but oxidative stress plays a major role in disease pathogenesis. Nuclear Magnetic Resonance (NMR) spectroscopy-based quantitative assessment of metabolites was performed to compare the activity of lactate dehydrogenase and phenylalanine hydroxylase between sepsis, septic shock, and disease control in sepsis and septic shock by comparing pyruvate/lactate (Pyr/Lac) and phenylalanine/tyrosine (Phe/Tyr) ratios. These ratios were evaluated and found to be used as an effective tool for diagnosis, prognosis, evaluation of disease activity, and treatment response.</p> <p> </p>
The Role of Endogenous Lactate in Brain Preservation and Counterregulatory Defenses Against Hypoglycemia
ClinicalTrials.gov study NCT02308293. IPD Sharing: Not stated. Countries: 1. Publications: 8.
Observation Alone for Mild Non-Lactational Mastitis
ClinicalTrials.gov study NCT06665399. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Effects of Glucose-fructose Drinks During Training on Lactate Transport
ClinicalTrials.gov study NCT01610986. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Relationship of Anesthesia Method With Serum Lactate Level in Craniotomies
ClinicalTrials.gov study NCT05145049. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Effect of Weight Loss and Lactation (the EVA-trial)
ClinicalTrials.gov study NCT03580057. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Acupuncture for Breast Engorgement During Lactation
ClinicalTrials.gov study NCT03230760. IPD Sharing: NO. Countries: 1. Publications: 3.
Aggressive Hydration With Lactated Ringer's Solution Versus Plasma Solution for the Prevention of Post ERCP Pancreatitis
ClinicalTrials.gov study NCT05832047. IPD Sharing: NO. Countries: 1. Publications: 1.
The Effect of Intravenous Lactate on Brain Lactate Concentrations During Hypoglycemia
ClinicalTrials.gov study NCT03286816. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Relevance of Veinous Lactates to Predict Postoperative Complications in Children 0-1 Years
ClinicalTrials.gov study NCT06909227. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Comparison of Ringer Lactate and Isotonic Acetate Solution as Perioperative Maintenance Fluid for Children
ClinicalTrials.gov study NCT02936167. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Lactate Profile and Fat Oxidation During Exercise
ClinicalTrials.gov study NCT05703100. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Vaccination Against COVID-19 in Pregnant and Lactating Women in Belgium
ClinicalTrials.gov study NCT05618548. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Pith Moromo 2: Cohort to Study Health Consequences of Food and Nutrition Insecurity During Pregnancy and Lactation
ClinicalTrials.gov study NCT02974972. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Whole Body Periodic Acceleration on Blood Lactate and Recovery
ClinicalTrials.gov study NCT02482597. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Hospital-based Paraprofessional Lactation Clinic
ClinicalTrials.gov study NCT00474422. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Lactate Kinetics in Septic Shock
ClinicalTrials.gov study NCT05349370. IPD Sharing: NO. Countries: 1. Publications: 1.
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