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174 results for “Motor cortex”
Data from: MRI-based visualization of rTMS-induced cortical plasticity in the primary motor cortex
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Data from: How does human motor cortex regulate vocal pitch in singers?
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Neural population dynamics in motor cortex are different for reach and grasp
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Data from: Coupling between motor cortex and striatum increases during sleep over long-term skill learning
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Evolution of the speech‐ready brain: The voice/jaw connection in the human motor cortex
<p>A prominent model of the origins of speech, known as the "frame/content" theory, posits that oscillatory lowering and raising of the jaw provided an evolutionary scaffold for the development of syllable structure in speech. Because such oscillations are non‐vocal in most non‐human primates, the evolution of speech required the addition of vocalization onto this scaffold in order to turn such jaw oscillations into vocalized syllables. In the present functional MRI study, we demonstrate overlapping somatotopic representations between the larynx and the jaw muscles in the human primary motor cortex. This proximity between the larynx and jaw in the brain might support the coupling between vocalization and jaw oscillations to generate syllable structure. This model suggests that humans inherited voluntary control of jaw oscillations from ancestral species, but added voluntary control of vocalization onto this via the evolution of a new brain area that came to be situated near the jaw region in the human motor cortex.</p>
Cerebellar Purkinje cells can differentially modulate coherence between sensory and motor cortex depending on region and behavior
<p>Dataset belonging to "Cerebellar Purkinje cells can differentially modulate coherence between sensory and motor cortex depending on region and behavior" (https://doi.org/10.1073/pnas.2015292118)</p>
Data from: Substance P signalling in primary motor cortex facilitates motor learning in rats
Among the genes that are up-regulated in response to a reaching training in rats, Tachykinin 1 (Tac1) - a gene that encodes the neuropeptide Substance P (Sub P) - shows an especially strong expression. Using Real-Time RT-PCR, a detailed time-course of Tac1 expression could be defined: a significant peak occurs 7 hours after training ended at the first and second training session, whereas no up-regulation could be detected at a later time-point (sixth training session). To assess the physiological role of Sub P during movement acquisition, microinjections into the primary motor cortex (M1) contralateral to the trained paw were performed. When Sub P was injected before the first three sessions of a reaching training, effectiveness of motor learning became significantly increased. Injections at a time-point when rats already knew the task (i.e. training session ten and eleven) had no effect on reaching performance. Sub P injections did not influence the improvement of performance within a single training session, but retention of performance between sessions became strengthened at a very early stage (i.e. between baseline-training and first training session). Thus, Sub P facilitates motor learning in the very early phase of skill acquisition by supporting memory consolidation. In line with these findings, learning related expression of the precursor Tac1 occurs at early but not at later time-points during reaching training.
Single-neuron Reconstruction of the Macaque Primary Motor Cortex
<div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div>Here are 26 reconstructed neuron SWC files of the primary motor cortex from a one-year-old cynomolgus monkey.</div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div> <div> <div> <div> <div> </div> </div> </div> </div> </div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div>In this study, we achieved visualization of neurons through sparse labeling and volumetric imaging with synchronized on-the-fly-scan and readout (VISoR) technique. Following whole-brain 3D reconstruction (<a href="https://github.com/SMART-pipeline/Volume-reconstruction" target="_blank" rel="noopener noreferrer">GitHub - SMART-pipeline/Volume-reconstruction</a>), we employed Lychnis for single-neuron reconstruction (<a href="https://github.com/SMART-pipeline/Lychnis-tracing" target="_blank" rel="noopener noreferrer">GitHub - SMART-pipeline/Lychnis-tracing</a>). Within Lychnis, the visualization toolkit (VTK) and virtual finger are utilized for 3D rendering and interactive labeling purposes.</div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> </div> </div> </div> </div> </div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div>The complete image datasets (raw and processed) of macaque brains exceed 1 petabyte, rendering it impractical to upload the entirety to a public data repository. This part of datasets generated and/or analyzed during the current study is available from the corresponding authors upon reasonable request.</div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div>
Data from: Perceptually relevant speech tracking in auditory and motor cortex reflects distinct linguistic features
During online speech processing, our brain tracks the acoustic fluctuations in speech at different timescales. Previous research has focused on generic timescales (for example, delta or theta bands) that are assumed to map onto linguistic features such as prosody or syllables. However, given the high intersubject variability in speaking patterns, such a generic association between the timescales of brain activity and speech properties can be ambiguous. Here, we analyse speech tracking in source-localised magnetoencephalographic data by directly focusing on timescales extracted from statistical regularities in our speech material. This revealed widespread significant tracking at the timescales of phrases (0.6–1.3 Hz), words (1.8–3 Hz), syllables (2.8–4.8 Hz), and phonemes (8–12.4 Hz). Importantly, when examining its perceptual relevance, we found stronger tracking for correctly comprehended trials in the left premotor (PM) cortex at the phrasal scale as well as in left middle temporal cortex at the word scale. Control analyses using generic bands confirmed that these effects were specific to the speech regularities in our stimuli. Furthermore, we found that the phase at the phrasal timescale coupled to power at beta frequency (13–30 Hz) in motor areas. This cross-frequency coupling presumably reflects top-down temporal prediction in ongoing speech perception. Together, our results reveal specific functional and perceptually relevant roles of distinct tracking and cross-frequency processes along the auditory–motor pathway.
Motor Learning After Cerebellar Damage: The Role of the Primary Motor Cortex
ClinicalTrials.gov study NCT05351255. IPD Sharing: YES. Countries: 1. Publications: 0.
Effects of Transcranial Focused Ultrasound on Human Primary Motor Cortex Using 7T fMRI
ClinicalTrials.gov study NCT03634631. IPD Sharing: NO. Countries: 0. Publications: 1.
Modulation of Motor Cortex Excitability by TMS and tDCS (MAGS1)
ClinicalTrials.gov study NCT03481309. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Investigating Motor Cortex Processing for Pain Modulation
ClinicalTrials.gov study NCT01404039. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Noninvasive VNS to Facilitate Excitability in Motor Cortex
ClinicalTrials.gov study NCT04130646. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Perceptually relevant speech tracking in auditory and motor cortex reflects distinct linguistic features
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Data from: Developmental 'awakening' of primary motor cortex to the sensory consequences of movement
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Data from: Substance P signalling in primary motor cortex facilitates motor learning in rats
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Data from: Dopamine promotes motor cortex plasticity and motor skill learning via PLC activation
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Evolution of the speech‐ready brain: The voice/jaw connection in the human motor cortex
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Changes in mature mouse primary motor cortex transcriptome after conditional Fezf2 knockdown
GEO Series GSE102365. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.