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14,544 results for “Prevention”
Fig 2 in Soluble total antigen derived from Toxoplasma gondii RH strain prevents apoptosis, but induces anti-apoptosis in human monocyte cell line
Fig 2. This schematic overview suggests signaling pathways of apoptosis. Apoptosis is induced through either the extrinsic pathway or intrinsic pathway. Toxoplasma gondii can prevent cell apoptosis via inhibition of cytochrome c release from the mitochondria into the cytosol, inhibition of cas-3, -6, -7, and -9 via blocking the mitochondrial pathway, and blocking cas-8 by external pathways. The parasite may also suppress pro-apoptotic protein (Bax) and induce anti-apoptotic Bcl-2 proteins and is able to activate transcription factors STAT6 and STAT3-miR-17-92-Bim pathway to inhibit apoptosis. Some proteins of T. gondii such as ROP18 plays a role in Fas/ CD95-mediated apoptosis to inhibit this process. Similarly ROP16 phosphorylates STAT3 and STAT6 to inhibit cell death. Original (S. Nemati).
Fig 1 in Soluble total antigen derived from Toxoplasma gondii RH strain prevents apoptosis, but induces anti-apoptosis in human monocyte cell line
Fig 1. The comparison of the expression levels of Bcl-2 (A), Mcl-1 (B), Cas-7 (C), Cas-3 (D), and Bax (E) in THP-1 cell line regarding different concentrations of the soluble total antigen of Toxoplasma gondii (Nicolle et Manceaux, 1908) STAg. NS: not significant; * P value <0.05; ** P value <0.01; *** P value <0.001.
Data from Commission for the Prevention of Corruption of the Republic of Slovenia: public-to-private transactions
<p>Public spending is often a contentious subject because different political parties have different agendas as to what should be the current national priorities. Of course, the same is true for the public in general. It is thus of interest to determine whether public spending is indeed as biased and capricious as it is often perceived, or whether there nevertheless exist some fundamental principles that guide it. We use data from the Commission for the Prevention of Corruption of the Republic of Slovenia, detailing every transfer of public money to the private sector from January 2003 to May 2020. During this time Slovenia has done business with no less than 248,989 companies. We find that the cumulative distribution of money received per company can be reasonably well explained by means of a power-law or a log-normal fit. We also show evidence for the first-mover advantage, and determine that the attachment rate of public spending to companies over time is roughly linear. These results indicate that Slovenian public spending is to a large extent guided by self organizing principles that, against all odds, go beyond nefarious interests and lobbying.</p>
Efficacy and Safety Study of DX-2930 to Prevent Acute Angioedema Attacks in Patients With Type I and Type II HAE
ClinicalTrials.gov study NCT02586805. IPD Sharing: YES. Countries: 7. Publications: 4.
Vortioxetine, 5, 10, and 20 mg, Relapse Prevention Study in Adults With Major Depressive Disorder (MDD)
ClinicalTrials.gov study NCT02371980. IPD Sharing: YES. Countries: 1. Publications: 1.
Efficacy, Safety, and Tolerability of Atogepant for the Prevention of Chronic Migraine
ClinicalTrials.gov study NCT03855137. IPD Sharing: YES. Countries: 17. Publications: 10.
Will Veterans Engage in Prevention After HRA-guided Shared Decision Making?
ClinicalTrials.gov study NCT01828567. IPD Sharing: YES. Countries: 1. Publications: 5.
Covered CP Stents for the Prevention or Treatment of Aortic Wall Injury Associated With Coarctation of the Aorta
ClinicalTrials.gov study NCT01278303. IPD Sharing: NO. Countries: 1. Publications: 1.
A Study to Test if Fremanezumab is Effective in Preventing Episodic Migraine in Patients 6 to 17 Years of Age
ClinicalTrials.gov study NCT04458857. IPD Sharing: YES. Countries: 9. Publications: 1.
CSL312 (Garadacimab) in the Prevention of Hereditary Angioedema Attacks
ClinicalTrials.gov study NCT04656418. IPD Sharing: YES. Countries: 7. Publications: 2.
Evaluating the Response to Two Antiretroviral Medication Regimens in HIV-Infected Pregnant Women, Who Begin Antiretroviral Therapy Between 20 and 36 Weeks of Pregnancy, for the Prevention of Mother-to
ClinicalTrials.gov study NCT01618305. IPD Sharing: YES. Countries: 7. Publications: 1.
Preventing Substance Use Among Youth
ClinicalTrials.gov study NCT04752189. IPD Sharing: YES. Countries: 1. Publications: 8.
A Study of Lanadelumab to Prevent Hereditary Angioedema (HAE) Attacks in Children
ClinicalTrials.gov study NCT04070326. IPD Sharing: YES. Countries: 5. Publications: 1.
Early Detection and Intervention for the Prevention of Psychosis
ClinicalTrials.gov study NCT00531518. IPD Sharing: YES. Countries: 1. Publications: 2.
Preventing Diabetic Foot Ulcers Through Cleaner Feet
ClinicalTrials.gov study NCT03503370. IPD Sharing: YES. Countries: 1. Publications: 1.
Organization-level Youth Engagement Approach for Substance Misuse Prevention
ClinicalTrials.gov study NCT05736211. IPD Sharing: NO. Countries: 1. Publications: 2.
Prevention of Urinary Stones With Hydration
ClinicalTrials.gov study NCT03244189. IPD Sharing: YES. Countries: 1. Publications: 3.
A Study of Long-Term Safety and Efficacy of Lanadelumab for Prevention of Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor
ClinicalTrials.gov study NCT04444895. IPD Sharing: YES. Countries: 10. Publications: 1.
EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy
ClinicalTrials.gov study NCT02676882. IPD Sharing: NO. Countries: 1. Publications: 1.
A Study Evaluating the Effectiveness of AMG 334 Injection in Preventing Migraines in Adults Having Failed Other Therapies
ClinicalTrials.gov study NCT03096834. IPD Sharing: YES. Countries: 16. Publications: 6.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.