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666 results for “Translocation”
Data for: Differential habitat use of a notorious invasive fish, the round goby, in a translocation-relevant system
<p>Anthropogenic structures can form novel ecosystem niches. Invasive species are often particularly successful in occupying these habitats and utilize them as beachheads for further spread. The invasive round goby (<em>Neogobius melanostomus</em>, Pallas 1814), an inherently bottom-dwelling fish, uses vertical harbour walls as habitat, enabling them to reach boats (i.e. potential translocation vectors). To evaluate the relevance of vertical habitat use for population dynamics and translocation, we exemplary investigated a population of round gobies in a harbour ecosystem. Specifically, we investigated differences in trophic niche characteristics, individual trophic specialization, phenotypic traits, and breeding frequency in wall versus bottom dwelling round gobies. Habitat-characteristic dietary signatures indicated habitat partitioning during the breeding season. Trophic niches overlapped but were clearly distinguishable between the habitats: walls were inhabited by 1.4 times more trophic generalists than specialists, while the bottom was inhabited by 2.1 times more trophic specialists. Breeding frequency was 24 times higher on the walls than on the bottom. After the reproductive season, we found a higher similarity in trophic ecology of gobies inhabiting the two habitats, and differences in abundance, size, and condition. These results are in line with winter migrations to deeper habitats, which are common in round gobies in lentic and marine ecosystems. Our results suggest a high potential for microgeographic adaptation to either horizontal or vertical habitat use in invasive round gobies. We demonstrated that male gobies using the walls during the breeding season are larger and heavier, <span>s</span>uggesting that wall-climbing may select for more competitive individuals. Additionally, the overall abundance of round gobies likely increases with the additional use of vertical habitat space, which may lead to higher propagule pressure. The ability to exploit anthropogenic habitats, and a higher translocation probability of competitive individuals, can contribute to the invasion success of round gobies in anthropogenically influenced aquatic systems.</p>
Absorption, translocation and distribution of imidacloprid in wheat
<p>The absorption, translocation and distribution of imidacloprid in wheat under hydroponic conditions were determined by LC-MS-MS. The results showed that imidacloprid could be absorbed by wheat, and imidacloprid was detected in both the roots and leaves of wheat.</p>
Dataset for Conformational dynamics of loop L3 in OmpF: Implications towards antibiotic translocation and voltage gating
<p>Dataset supporting the work in the publication titled, "Conformational dynamics of loop L3 in OmpF: Implications towards antibiotic translocation and voltage gating".</p>
Sod translocation to restore habitats of the myrmecophilous butterfly Phengaris (Maculinea) teleius on former agricultural fields
<p>In Europe, 50-70% of former natural grassland area has been destroyed during the past 30 years due to land use changes, losses are expected to increase in the future. Restoration is thought to reverse this situation by creating suitable abiotic conditions. In this paper, we investigate the effects of sod translocation with specific vegetation to facilitate the restoration of a former intensive agricultural field into a wet meadow. First, starting conditions were optimized including modification of the local hydrology, removal of the fertilized topsoil, application of liming, and translocation of fresh clippings as a seed source. The second part aimed at restoring the habitat for the butterfly species <em>Phengaris (Maculinea) teleius</em>, one of the species that was especially affected by the loss of wet meadows. This species engages in a complex myrmecophilous relationship with one host plant, <em>Sanguisorba officinalis</em>, and one obligate host ant, <em>Myrmica scabrinodis</em>. We used sod translocation to create islands of habitat to promote host plant and host ant colonization. After four years following the restoration, we observed that plants spread from the transplanted sods to the surroundings. The vegetation composition and structure of the transplanted sods attracted colonization of <em>Myrmica </em>ants into the restored areas. Following the increase in vegetation cover and height, <em>Myrmica </em>ant colonies further spread into the restored areas. Therefore, sod translocations can be considered an effective restoration method following topsoil removal in the process of restoring wet meadows to provide a starting point for ant colonization and plant dispersion. With these findings, this paper contributes to the evidence-based restoration of wet meadows on former agricultural fields, including complex interactions between invertebrates and their required ecological relationships. </p>
Incorporating Human Dimensions Improves Wildlife Translocation Outcomes
<p>Raw dataset used for manuscript currently under review. </p>
A novel SNP assay reveals increased genetic variability and abundance following translocations to a remnant Allegheny woodrat population
<p><strong>Background</strong>: Allegheny woodrats (<em>Neotoma magister</em>) are found in metapopulations distributed throughout the Interior Highlands and Appalachia. Historically these metapopulations persisted as relatively fluid networks, enabling gene flow between subpopulations and recolonization of formerly extirpated regions. However, over the past 45 years, Allegheny woodrat populations have experienced population declines throughout their range due to a combination of habitat destruction, declining hard mast availability, and roundworm parasitism. In an effort to initiate genetic rescue of a small, genetically depauperate subpopulation in New Jersey, woodrats were translocated from a genetically robust population in Pennsylvania (PA) in 2015, 2016, and 2017. Herein, we assess the efficacy of these translocations to restore genetic diversity within the recipient population. </p> <p><strong>Results</strong>: We designed a novel 134 single nucleotide polymorphism panel, which was used to genotype the six woodrats translocated from PA and 82 individuals from the NJ population captured before and after the translocation events. These data indicated that a minimum of two translocated individuals successfully produced at least 16 offspring, who reproduced as well. Further, population-wide observed heterozygosity rose substantially following the first set of translocations, reached levels comparable to that of populations in Indiana and Ohio, and remained elevated throughout the following years. Abundance also increased during the monitoring period, suggesting Pennsylvania translocations initiated the genetic rescue of the New Jersey population.</p> <p><strong>Conclusions</strong>: Our results indicate, encouragingly, that very small numbers of translocated individuals can successfully restore the genetic diversity of a threatened population. Our work also highlights the risks of managing very small populations, such as when translocated individuals have greater reproductive success relative to residents. Finally, we note that ongoing work with Allegheny woodrats may broadly shape our understanding of genetic rescue within metapopulations and across heterogeneous landscapes.</p>
Data from: Translocation precipitates natural hybridisation and pervasive introgression between marine gastropods with divergent developmental modes
<div> <div> <div> <p>Assisted colonisation, the introduction of species beyond their historical range, is increasingly necessary for conserving species. However, empirical evidence of the long-term genetic outcomes of assisted colonisation is grossly lacking. A risk associated with moving species beyond their native range is the possibility of interspecific hybridisation with a closely related species, potentially resulting in outbreeding depression or the genetic swamping of a parental species. Here, we use a combination of genome-wide Single Nucleotide Polymorphism (SNP) markers and mitochondrial DNA sequencing to determine the long-term genetic consequences of introducing the intertidal periwinkle <em>Bembicium vittatum</em> (a direct developer) beyond its native range and into the native range of its congener <em>Bembicium auratum</em> (a species with planktotrophic larval dispersal). We found novel evidence of natural, multigenerational hybridisation between marine invertebrates with different modes of development. Intriguingly, introgression was highly asymmetrical initially, but became more evenly bidirectional as the population became more admixed. There was a significant decline in the frequency of alleles from the introduced <em>B. vittatum</em> over time, providing evidence of genetic swamping. The present study also provides potential evidence of outbreeding depression, in the form of cytonuclear incompatibilities, leading to the observed pattern of asymmetrical introgression. This study reveals the potential for unexpected mixing between species when reproductive barriers are not well understood, resulting in failure of pure <em>B. vittatum</em> to persist at the translocation site, a major concern associated with assisted colonisation. Without long-term genetic monitoring interspecific hybridisation between <em>B. vittatum</em> and <em>B. auratum</em> would have gone undetected, highlighting the importance of long-term monitoring to detect unintentional negative consequences of conservation translocations. Successful assisted colonisation requires an understanding of the potential for interspecific hybridisation between the threatened species and closely related native species, to reduce the risk of adverse outcomes.</p> </div> </div> </div>
Data from: Translocation experiment of taiga bean geese Anser fabalis provides evidence for oblique social learning of moult migration
<p>While there is ample evidence supporting genetic control of migratory behaviour in short-lived passerines, long-lived social species have been assumed to rely solely on cultural inheritance of migratory routes. Evidence from experimental studies supporting this idea is scarce. We tested whether the moult migration in taiga bean geese <em>Anser fabalis </em>has an inherited component or whether the birds need oblique social learning (where knowledge on migration is transferred from any experienced individual to any naïve individual conspecific) to carry out this journey. In many waterfowl species, non-breeders and failed breeders migrate to remote places for wing moult while successful breeders stay at the breeding grounds and moult with their chicks. We translocated one-year-old taiga bean geese before their first moult migration to sites outside of the breeding range to examine whether they display innate moult migration behaviour without experienced conspecifics or not. The birds were equipped with GPS-transmitters and released in randomly assigned groups of two. Wild control one-year-old birds were released immediately after capture with other non-breeding geese, while a procedural control group consisting of older birds was held in captivity until released at the same time with the translocated one-year-old birds but in the place where they were captured. Most translocated birds found conspecifics and either joined locally moulting breeders or followed experienced birds to moulting sites in Russia. Two of the translocated birds did not find other bean geese and settled to moult together in SW Finland. The wild control birds moult-migrated as expected, while only one of the procedural control birds moult-migrated to Russia and the remaining three stayed with locally moulting breeders in Finland. Our results support the idea that moult migration in geese is culturally inherited, highlighting the importance of the non-relative, experienced adult individuals have in maintaining population-specific behaviours.</p>
Code and data for "Comparing cost-effectiveness of radio and drone telemetry with playback surveys for assessing translocation outcomes"
<p><strong>Overview</strong></p> <p>Code and data used for the analyses of Stone et al., 2024 "Comparing cost-effectiveness of radio and drone telemetry with playback surveys for assessing translocation outcomes". Forthcoming in Journal of Applied Ecology</p> <p><strong>Abstract</strong></p> <p>1. Post-release monitoring is critical for assessing translocation outcomes. Yet the quality of information gained from monitoring can vary greatly, and perceived monitoring costs often results in reduced monitoring effort. Selecting cost-effective monitoring strategies that provide high quality data is therefore important for assessing translocation outcomes and making informed management decisions. <br>2. To compare how monitoring strategy affects information gained, we monitored a toutouwai/North Island robin (Petroica longipes) reintroduction in Aotearoa New Zealand, based on monitoring objectives of determining survival, site fidelity and whether the extent of management was large enough to protect dispersing individuals. We compared how these objectives were met through four monitoring strategies: 1) comprehensive surveys with ground radio telemetry and playback; 2) aerial drone telemetry; 3) dedicated playback by trained surveyors and 4) opportunistic playback by predator control contractors. We undertook a viewshed analysis to determine search coverage of each strategy and compared detection rates, efficiency, and cost. <br>3. Comprehensive ground telemetry and playback, while costly, covered the largest area and provided the most accurate data on dispersal, survival and the translocation outcome. In comparison, opportunistic playback monitoring detected substantially fewer individuals, giving a false impression of low site fidelity and survival and a failed translocation. Although drone telemetry had considerable site-specific limitations, which limited its effectiveness during our study, it was the most cost-effective with a high detection rate and low search effort. <br>4. Synthesis and applications: Our study shows the value of intensive monitoring in facilitating management decisions for wildlife translocations. Comprehensive telemetry and playback, while costly, were invaluable for gaining high quality information on the translocation outcome. Without suitable monitoring, reintroduction outcomes can be difficult to assess and potentially result in unnecessary, ineffective, or overly expensive management actions. We recommend that monitoring intensity and methodology should reflect the site, species and level of uncertainty regarding the translocation outcome. Prioritising monitoring can help reduce long-term costs, increase quality of information gained and allow for more informed management decisions that can improve subsequent translocation outcomes.</p>
Research data supporting "Investigating the accumulation and translocation of titanium dioxide nanoparticles with different surface modifications in static and dynamic human placental transfer models"
<p>Research data supporting the publication: Aengenheister, L. et al., 2019, "Investigating the accumulation and translocation of titanium dioxide nanoparticles with different surface modifications in static and dynamic human placental transfer models", Eur J Pharm Biopharm. https://doi.org/10.1016/j.ejpb.2019.07.018</p>
Source population and time spent in captivity affect survival and reproduction of long-distance translocated northern bobwhites
<p>Northern bobwhites (<em>Colinus virginianus</em>) have become a species of great conservation priority because of widespread and ongoing population declines. Long-distance translocations are becoming increasingly used to access a source population with densities high enough to support translocation. Two key uncertainties exist regarding the efficacy of long-distance translocations: choosing a source population with adaptations that will be successful in a novel environment and mitigating the stress response common during the translocation process. We translocated bobwhites from the South Texas Plains and the Floridian Coastal Plain to a recipient site in the Floridian Coastal Plain in 2021 and 2022 to compare the survival and productivity of bobwhites translocated from two different source populations. We also evaluated how varying holding times during the translocation process influenced the success of the translocated individuals. Breeding season survival, nest propensity, and fecundity were greater for Florida resident and Florida translocated bobwhites relative to Texas translocated bobwhites. We observed high rates of mortality during the transport and holding processes, but holding time did not affect breeding season survival of Texas translocated bobwhites. Both nest success and fecundity of Texas translocated bobwhites were negatively affected by holding time. Bobwhites translocated long distances may have the adaptive capacity to be successful in novel environments, but the consequences of translocation stress can be detrimental. Future translocation planning should consider choosing source populations from similar ecoregions to simultaneously decrease translocation distances and potential stress from translocation.</p>
Integrating socio-ecological suitability with human-wildlife conflict risk: Case study for translocation of a large ungulate
<p>1. Translocations are essential for reestablishing wildlife populations. As they sometimes fail, it is critical to assess factors that influence their success pre-translocation.</p> <p>2. Socio-ecological suitability models (SESMs) integrate social acceptance and ecological suitability to enable identification of areas where wildlife populations will expand, which makes it likely that SESMs will also be useful for predicting translocation success.</p> <p>3. To inform site-selection for potential elk (Cervus canadensis) reintroduction to northeastern Minnesota, USA, we developed broad-scale maps of social acceptance from surveys of local residents and landowners, animal use equivalence (AUE) from forage measured in the field, and empirical conflict risk from geospatial data. Resulting SESMs integrated social acceptance favorability scores, AUE, and conflict risk, and weighted SESMs showed the relative influences of acceptance and conflict.</p> <p>4. Social acceptance was positive for local residents and landowners (mean ≥ 5.4; scale of 1 to 7). AUE (scaled to an elk home range) ranged between 1 and 9 elk/16 km2 during winter, and from 14 to 83 elk/16 km2 during summer. Human-elk conflict risk was low (mean ≤ 0.10; scaled 0 to 1), increasing from north to south. Geographical distributions differed for social acceptance, AUE, and conflict risk, and weighted SESMs revealed unsuitable areas that were otherwise obscured.</p> <p>5. <em>Synthesis and applications</em>. Integrating human-wildlife conflict risk into SESMs shows where social acceptance of translocated species is likely to erode, even where viewed favorably pre-translocation, to inform translocation planning by highlighting interactions between key factors. Such integrated models supplement existing reintroduction biology frameworks by supporting decision-making and knowledge development. In northeastern Minnesota, natural resource managers who are considering elk reintroductions are using SESMs reported here to identify where human-elk conflict is likely to result in an isolated elk population and where addressing concerns for area residents about conflict risk is essential.</p>
Post-translocation dynamics of black-tailed prairie dogs (Cynomys ludovicianus): A successful conservation and human-wildlife conflict mitigation tool
<p>Prairie dogs have declined by 98% throughout their range in the grasslands of North America. Translocations have been used as a conservation tool to reestablish colonies of this keystone species and to mitigate human-wildlife conflict. Understanding the behavioral responses of prairie dogs to translocation is of utmost importance to enhance the persistence of the species and for species that depend on them, including the critically endangered black-footed ferret. In 2017 and 2018, we translocated 658 black-tailed prairie dogs on the Lower Brule Indian Reservation in central South Dakota, USA, a black-footed ferret recovery site. Here, we describe and evaluate the effectiveness of translocating prairie dogs into augered burrows and soft released within presumed coteries to reestablish colonies in previously occupied habitat. We released prairie dogs implanted with passive integrated transponders (PIT tags) and conducted recapture events approximately 1-month and 1-year post-release. We hypothesized that these methods would result in a successful translocation and that prairie dogs released as coteries would remain close to where they were released because of their highly social structure. In support of these methods leading to a successful translocation, 69% of marked individuals were captured 1-month post-release, and 39% were captured 1-year post-release. Furthermore, considerable recruitment was observed with 495 unmarked juveniles captured during the 1-year post-release trapping event, and the reestablished colony had more than doubled in area by 2021. Contrary to our hypothesis, yet to our knowledge a novel finding, there was greater initial movement within the colony 1-month post-release than expected based on recapture locations compared to published average territory size; however, 1-year after release most recaptured individuals were captured within the expected territory size when compared to capture locations 1-month post-release. This research demonstrates that while translocating prairie dogs may be socially disruptive initially, it is an important conservation tool.</p>
Temporal variation in translocated Isle Royale wolf diet
<p>Wolves (<em>Canis lupus</em>) can exert top-down pressure and shape ecological communities through predation of ungulates and beavers (<em>Castor</em> spp.). Therefore, understanding wolf foraging is critical to estimating their ecosystem-level effects. Specifically, if wolves are consumers that optimize tradeoffs between costs and benefits of prey acquisition, changes in these factors may lead to prey switching or negative-density dependent selection with potential consequences for community stability. For wolves, factors affecting cost and benefits include prey vulnerability, risk, reward, and availability which can vary temporally. We described wolf diet by frequency of occurrence and percent biomass and characterized diet using prey remains found in wolf scats on Isle Royale National Park, Michigan, USA during May–October 2019 and 2020. We used logistic regression to estimate prey consumption over time. We predicted prey with temporal variation in cost (availability and/or vulnerability) such as adult moose (<em>Alces</em> <em>alces</em>), calf moose, and beaver (Castor canadensis) to vary in wolf diets. We analyzed 206 scats and identified 62% of remains as beaver, 26% as moose, and 12% as other species (birds, smaller mammals, and wolves). Adult moose were more likely to occur in wolf scats in May, when moose are in poor condition following winter. The occurrence of moose calves peaked during June–mid July following birth but before calf vulnerability declined as they matured. In contrast, beaver occurrence in wolf scat did not change over time, reflecting the importance of low-handling cost prey items for recently introduced lone or paired wolves. Our results demonstrate that wolf diet is responsive to temporal changes in prey costs. Temporal fluctuation in diet may influence wolves' ecological role if prey respond to increased predation risk by altering foraging or breeding behavior.</p>
Agronomic and quality impact of a shortened translocation for wheat streak mosaic virus resistance
<p class="H1"><em><span>Wheat streak mosaic virus</span></em><span> (WSMV) </span><span>is a mite-vectored virus with substantial economic impact on wheat production. One of the effective sources of resistance to WSMV, <em>Wsm1</em>, is carried on a translocation from <em>Thinopyrum intermedium. </em>The original whole arm form of this translocation (T4DL·4J<sup>s</sup>S) was highly effective against WSMV but carried a substantial yield penalty in the absence of the virus. Shorter recombinants of the <em>Th. intermedium </em>translocation are now available. This study characterized the agronomic performance of near-isogenic sib-pair families in ten yield trials using one of these shortened T4DL·4DS-4J<sup>s</sup>S translocations, named 'rec213', in the absence of visible disease. This translocation had no effect on heading date, was associated with a modest reduction (≤ 4.8 cm) in plant height, and the translocation had a favorable effect (≤ 12.6%) on grain yield in those environments where highly significant genotype effects were detected. The translocation did not affect protein concentration or lactic acid-sodium dodecyl sulfate solvent retention capacity, a measure of gluten quality. However, families with the translocation had slightly (≤ 5%) lower protein quality scores than paired families without the translocation. We do not expect this modest difference in quality to be a barrier to utilization of the rec213 translocation for <em>Wsm1</em>, but we encourage breeders to work within high quality genetic backgrounds in when using the rec213 translocation, and to monitor the quality of breeding selections. Improved codominant PCR-based marker assays were developed to facilitate the use of the rec213 <em>Wsm1 </em>trait in breeding programs.</span></p>
Individual multilocus genotypes of F1 seed progeny and recruits from two translocated populations of Campanula glomerata
<p>Individual multilocus genotypes for 15 microsatellite loci and spatial coordinates of F1 seed progeny and recruits from two translocated populations of <em>Campanula glomerata </em>from southern Belgium. For more information, see Van Rossum et al.(2023), Assessing spatial mating patterns in translocated populations of <em>Campanula glomerata, </em>in <em>Gobal Ecology and Conservation.</em></p> <p> </p> <p> </p>
Expulsion mechanism of the substrate-translocating subunit in ECF transporters
<p>Data for coarse-grained molecular dynamics simulations (final snapshots, cleaned trajectories, starting structure/simulation parameters) described in "Expulsion mechanism of the substrate-translocating subunit in ECF transporters".</p>
A major myna problem; invasive predator removal benefits female survival and population growth of a translocated island endemic
<p>Invasive predators are a major driver of extinctions and continue to threaten native populations worldwide. Island eradications of (mostly mammalian) invasive predators have facilitated the reestablishment of numerous island-endemic populations. Other invasive taxa, such as some predatory birds, could pose a more persistent threat due to their ability to fly and actively re-invade even remote and isolated islands. However, the impact of invasive predatory birds has been largely overlooked. We report on a novel sex-specific impact of an invasive-nest predator, the common myna (<span><em>Acridotheres</em> <em>tristis</em></span>), on a reintroduced population of Seychelles warblers (<span><em>Acrocephalus</em> <em>sechellensis</em></span>); translocated from Cousin Island to Denis Island in 2004. Regular post-translocation monitoring revealed that female mortality was 20 % higher than males, leading to a 60<span>–</span>70 % male-biased population sex-ratio between 2005 and 2015. This was attributed to common mynas inflicting severe injuries to incubating female Seychelles warblers while attempting to prey upon eggs in their nests. These effects likely contributed to the slower-than-expected population growth observed (relative to previous translocations of Seychelles warblers to other islands) over the same period. An eradication programme beginning in 2011 removed all common mynas from Denis by 2015. Subsequently, we observed a balancing of sex-specific survival and the population sex-ratio of Seychelles warblers and, consequently, accelerated population growth. This study demonstrates the importance of assessing the threat posed by all invasive taxa (not just mammals) to island conservation. Furthermore, we show how extended monitoring is needed to identify problems and develop solutions, post-translocation.</p>
Translocation of linearized full-length proteins through an engineered nanopore under opposing electrophoretic force
<p>This database contains raw electrophysiology data and MD data, organised in two parts: part 1 corresponds to electrophysiology traces and part 2 corresponds to MD files. For detailed information see below.</p> <p><strong>Part 1: electrophysiology data </strong></p> <p>Data separated in two main categories: main text data and SI (only) data. The electrophysiology data is named in the following format: </p> <p>main_FnX_CytK mutant_buffer_substrate_cis_applied potential, where n = figure number and X = panel</p> <p>Data from the main text:</p> <p><strong>Figure 2</strong>:</p> <p>--> C) CytK WT + S1 substrate (file names start with main_F2C_CytK WT)</p> <p>--> D) CytK 2E-4D (K128D K155D Q145D S151D) + S1 substrate (main_F2D...)</p> <p>--> E) CytK 2E-4D (K128D K155D Q145D S151D) + tzatziki substrate (main_F2E...)</p> <p>--> F) CytK 2E-4D (K128D K155D Q145D S151D) + mujdei substrate (main_F2F...)</p> <p><strong>Figure 4</strong>:</p> <p>--> CytK 2E-4D (K128D K155D Q145D S151D/ 4D) + malE219a substrate (main_F4A...)</p> <p>--> CytK 2E-4D (K128D K155D Q145D S151D/ 4D) + H152A-GBP substrate (main_F4B...)</p> <p>--> CytK 2E-4D (K128D K155D Q145D S151D/ 4D) + W30G-W133L-DHFR substrate (main_F4C...)</p> <p> </p> <p><strong>Supporting information figures </strong></p> <p>general name: SI_Sx_CytK mutant_buffer_substrate_cis_applied potential, where x = number figure from supporting information</p> <p> </p> <p>Figure S4. S1 translocation through the K128D K155D CytK mutant nanopore --> SI_S4...</p> <p>Figure S5. S1 translocation through the K128D K155D Q145D CytK mutant nanopore --> SI_S5...</p> <p>Figure S6. S1 translocation through the K128D K155D T147D CytK mutant nanopore --> SI_S6...</p> <p>Figure S7. Translocation of S1 through the 2E-1D-1Q-Q122D-CytK nanopore --> SI_S7...</p> <p>Figure S8. Translocation of S1 through 2E-4D-CytK nanopores --> see F2D main text (main_F2D...)</p> <p>Figure S9. Tzatziki and the CytK 2E-2D nanopore --> SI_S9...</p> <p>Figure S10. Tzatziki translocation through the K128D Q145D S151D K155D CytK nanopore --> see F2D main text (main_F2E...)</p> <p>Figure S11. Tzatziki translocation through the K128D K155D Q145D CytK nanopore --> SI_S11...</p> <p>Figure S12. Tzatziki translocation through the K128D K155D T147D CytK mutant nanopore --> SI_S12...</p> <p>Figure S14. Translocation of mujdei through 2E-4D-CytK nanopores --> see F2D main text (main_F2F...)</p> <p>Figure S22. Translocation of malE219a through 2E-4D-CytK nanopores in 2 M urea --> see F4A main text (main_F4A...)</p> <p>Figure S23: Translocation GBP H152A through the 2E-4D CytK nanopore in 2.4 M urea --> see F4B main text (main_F4B...)</p> <p>Figure S24. Translocation of W30G-W133L-DHFR through 2E-4D-CytK nanopore in 2.6 M urea --> see F4B main text (main_F4B...)</p> <p>Figure S26. MalE219a translocation through the 2E-4D CytK mutant in 1 M and 1.8 M Gu.HCl --> SI_S26... (1 M GuHCl and 1.8 M GuHCl are included in the file name)</p> <p>Figure S27: WT-CytK tested with the malE219a and malE219aD10ssrA proteins in 1.5 M Gu.HCl --> SI_S27...</p> <p>Original SDS-PAGE gels of the substrates in a powerpoint file</p> <p> </p> <p><strong>Part 2: MD data</strong></p> <p>The data corresponding to the MD simulations is bundled in a zip file named MD_files.zip</p> <p>This file contains the following subfiles linked to <strong>main text Figure 3</strong>:</p> <p><em>panel A</em>:</p> <p>- main_F3A_CytK_E2-D2 </p> <p>- main_F3A_CytK_E2-D3</p> <p>- main_F3A_CytK_E2-D4</p> <p>- main_F3A_CytK_WT</p> <p><em>panels C, D and E</em>:</p> <p>- main_F3CDE_CytK_E2-D4_rep1</p> <p>- main_F3CDE_CytK_E2-D4_rep2</p> <p>- main_F3CDE_CytK_E2-D4_rep3</p> <p>and files linked to the supporting information <strong>Figure S20</strong>:</p> <p>- SI_S20_ABC_CytK_E2-D4_TZA11_rep1</p> <p>- SI_S20_ABC_CytK_E2-D4_TZA11_rep2</p> <p>- SI_S20_ABC_CytK_E2-D4_TZA11_rep3</p>
Study to IDEntify Patients With Advanced/Metastatic Non Small Cell Lung Cancer (NSCLC) and ALK and ROS1 Translocation and to Establish Their Therapeutic Management (IDEALK&ROS)
ClinicalTrials.gov study NCT02679170. IPD Sharing: NO. Countries: 1. Publications: 1.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.