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202
datasets available to search
ShareScore release 0.9.0
Dataset results
202 results for “contractility”
Cardiac Contractility Modulation Therapy in Amyloid Cardiomyopathy Patients With Heart Failure
ClinicalTrials.gov study NCT05167799. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Resistance Training Effects on Muscle Morphological, Mechanical and Contractile Properties
ClinicalTrials.gov study NCT04845295. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Optimising Pacemaker Therapy for Contractility
ClinicalTrials.gov study NCT02964650. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Influence of High Intensity Exercise on Insulin Resistance, Muscle Contractile Properties, Aerobic Capacity and Body Composition in Multiple Sclerosis
ClinicalTrials.gov study NCT01845896. IPD Sharing: Not stated. Countries: 1. Publications: 3.
In Vitro Optimization of Oxytocin-induced Myometrial Contractility by Propranolol
ClinicalTrials.gov study NCT03434444. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Contractile Cross Sectional Areas and Muscle Strength in Patients With Congenital Myopathies
ClinicalTrials.gov study NCT03018184. IPD Sharing: NO. Countries: 1. Publications: 2.
Sensor location affects skeletal muscle contractility parameters measured by tensiomyography
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Repolarization and contractility in hypertrophic cardiomyopathy patients
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Right ventricular contractility and load in HIV associated pulmonary hypertension
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A study of gene expression, structure, and contractility of iPSC-Derived Cardiac Myocytes from a family with heart disease due to LMNA mutation
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Data from: Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes
Cardiomyocytes from human induced pluripotent stem cells (hiPSC-CMs) are increasingly recognized as valuable for determining the effects of drugs on ion channels but they do not always accurately predict contractile responses of the human heart. This is in part attributable to their immaturity but the sensitivity of measurement tools may also be limiting. Measuring action potential, calcium flux or contraction individually misses critical information that is captured when interrogating the complete excitation-contraction coupling cascade simultaneously. Here, we develop an hypothesis-based statistical algorithm that identifies mechanisms of action. We design and build a high-speed optical system to measure action potential, cytosolic calcium and contraction simultaneously using fluorescent sensors. These measurements are automatically processed, quantified and then assessed by the algorithm. Multiplexing these three critical physical features of hiPSC-CMs allows identification of all major drug classes affecting contractility with detection sensitivities higher than individual measurement of action potential, cytosolic calcium or contraction.
Molecular dynamics initialization files to reproduce simulations in "Anillin-Related Mid1 as an Adaptive and Multimodal Contractile Ring Anchoring Protein: A Simulation Study"
<p>Molecular dynamics initialization files to reproduce simulations in "Anillin-Related Mid1 as an Adaptive and Multimodal Contractile Ring Anchoring Protein: A Simulation Study" by Aaron R. Hall, Yeol Kyo Choi, Wonpil Im, and Dimitrios Vavylonis, Structure (2024) https://doi.org/10.1016/j.str.2023.11.010</p>
Microscopy imaging of the contractility assay for 2 donors in the different conditions and timepoints (14)
<p>Microscopy imaging of the contractility assay for donor 1, 24h, inib</p>
The Effects of 4 Week β-alanine Supplementation on Knee Extensor Contractile and Force Properties in the Over 60s
ClinicalTrials.gov study NCT03111979. IPD Sharing: NO. Countries: 0. Publications: 4.
Hemodynamic and Echocardiographic Assessment of Riociguat Effects on Myocardial Wall Contractility and Relaxation Kinetics
ClinicalTrials.gov study NCT01065051. IPD Sharing: Not stated. Countries: 1. Publications: 0.
β-alanine Supplementation on Knee Extensor Contractile and Force Properties
ClinicalTrials.gov study NCT02819505. IPD Sharing: NO. Countries: 0. Publications: 5.
Data from: Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes
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Human iPSC-cardiomyocyte models of insulin resistance demonstrate metabolic and contractile dysfunction that recapitulates diabetic cardiomyopathy
GEO Series GSE288708. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart [ChIP-seq]
GEO Series GSE196438. Rattus norvegicus. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Vascular smooth muscle cell contractile protein expression is increased through protein kinase G-dependent and –independent pathways by glucose-6-phosphate dehydrogenase inhibition and deficiency
GEO Series GSE80972. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.