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1,294
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1,294 results for “hemodynamics”
Hemodynamic-GUIDEd Management of Heart Failure
ClinicalTrials.gov study NCT03387813. IPD Sharing: NO. Countries: 2. Publications: 5.
Trauma Study: Early Warning of Progression Toward Hemodynamic Deterioration After Trauma
ClinicalTrials.gov study NCT04912232. IPD Sharing: NO. Countries: 1. Publications: 8.
Effects of Voluven on Hemodynamics and Tolerability of Enteral Nutrition in Patients With Severe Sepsis
ClinicalTrials.gov study NCT00464204. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Hemodynamic and Functional Characteristics of the Cerebral Circulation in Obesity
ClinicalTrials.gov study NCT06067113. IPD Sharing: NO. Countries: 1. Publications: 8.
Hemodynamic Responses During Induction: Comparison of Marsh and Schnider Pharmacokinetic Models
ClinicalTrials.gov study NCT01759160. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Evaluation of Hemodynamic Parameters Following Transjugular Intrahepatic Portosystemic Shunt (TIPS)
ClinicalTrials.gov study NCT04050683. IPD Sharing: YES. Countries: 1. Publications: 16.
The Effects of Vyvanse(TM) on Brain Hemodynamics and Reading
ClinicalTrials.gov study NCT00733356. IPD Sharing: NO. Countries: 1. Publications: 1.
Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade.
ClinicalTrials.gov study NCT02025075. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Acute Effects of Inorganic Nitrite on Cardiovascular Hemodynamics in Heart Failure With Preserved Ejection Fraction
ClinicalTrials.gov study NCT01932606. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Percutaneous Hemodynamic Support With Impella 2.5 During Scar-related Ventricular Tachycardia Ablation
ClinicalTrials.gov study NCT01294267. IPD Sharing: NO. Countries: 1. Publications: 1.
Effect of Magnesium Sulfate on Hemodynamics on Laparoscopic Cholecystectomy Patients
ClinicalTrials.gov study NCT07079514. IPD Sharing: YES. Countries: 1. Publications: 7.
Data from: The global effect of aortic coarctation on carotid and renal pulsatile hemodynamics
Open the record for dataset details and reuse information.
Dobutamine improves hemodynamics and oxygen delivery in standing and isoflurane-anesthetized horses
Open the record for dataset details and reuse information.
Four-dimensional computational ultrasound imaging of brain hemodynamics
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Data from: Empirical targets for acute hemodynamic management of individuals with spinal cord injury
Objective: To determine the hemodynamic conditions associated with optimal neurological improvement in acute traumatic spinal cord injury (SCI) individuals who had lumbar intrathecal catheters placed to measure cerebrospinal fluid pressure (CSFP). Methods: Ninety-two acute SCI individuals were enrolled in this multi-center prospective observational clinical trial. We monitored mean arterial pressure (MAP) and CSFP during the first week post-injury, and assessed neurologic function at baseline and six-months post-injury. We used relative risk iterations to determine transition points at which the likelihood of either improving neurologically or remaining unchanged neurologically was equivalent. These transition points guided our analyses where we examined the linear relationships between time spent within target hemodynamic ranges (i.e., clinical adherence) and neurological recovery. Results: Relative risk transition points for CSFP, MAP, and spinal cord perfusion pressure (SCPP) were linearly associated with neurological improvement and directed the identification of key hemodynamic target ranges. Clinical adherence to the target ranges was positively and linearly related to improved neurological outcomes. Adherence to SCPP targets, not MAP targets, was the best indicator of improved neurological recovery, which occurred with SCPP targets of 60-65 mmHg. Failing to maintain the SCPP within the target ranges was an important detrimental factor in neurologic recovery, particularly if the target range is set lower. Conclusion: We provide an empirical, data-driven approach to aid institutions in setting hemodynamic management targets that accept the real-life challenges of adherence to specific targets. Our results provide a framework to guide the development of widespread institutional management guidelines for acute traumatic SCI.
Data from: Sex-dependent differences in central artery hemodynamics in normal and fibulin-5 deficient mice: implications for ageing
Mouse models provide unique opportunities to study vascular disease, but they demand increased experimental and computational resolution. We describe a workflow for combining in vivo and in vitro biomechanical data to build mouse-specific computational models of the central vasculature including regional variations in biaxial wall stiffness, thickness and perivascular support. These fluid–solid interaction models are informed by micro-computed tomography imaging and in vivo ultrasound and pressure measurements, and include mouse-specific inflow and outflow boundary conditions. Hence, the model can capture three-dimensional unsteady flows and pulse wave characteristics. The utility of this experimental–computational approach is illustrated by comparing central artery biomechanics in adult wild-type and fibulin-5 deficient mice, a model of early vascular ageing. Findings are also examined as a function of sex. Computational results compare well with measurements and data available in the literature and suggest that pulse wave velocity, a spatially integrated measure of arterial stiffness, does not reflect well the presence of regional differences in stiffening, particularly those manifested in male versus female mice. Modelling results are also useful for comparing quantities that are difficult to measure or infer experimentally, including local pulse pressures at the renal arteries and characteristics of the peripheral vascular bed that may differ with disease.
A Dataset of Reconstructed Carotid Bifurcation Lumen and Plaque Models with Centerline Tree and Simulated Hemodynamics
<p><code>carotid_bifurcation_database.zip</code> contains 79 cases of left and right-side carotid bifurcations (152 inner wall models). For each case, inner wall (lumen) and plaque models were extracted from computed tomography angiography (CTA) scans. The models were segmented, reconstructed, and a centerline tree was created for each geometry using the <a href="https://github.com/PepeEulzer/CarotidAnalyzer">CarotidAnalyzer</a> pipeline. The geometries include varying degrees of internal carotid stenosis. Bifurcations with 100% stenosis were omitted, as the vessel is not discernible in the scan.</p> <p><code>carotid_flow_database.zip</code> contains hemodynamic flow simulations of the above models. Fluid data (velocity, pressure) and surface data (wall shear stress) are given in seperate files for each case. For each field, a systolic and diastolic time step are provided.</p> <p><strong>Further information regarding the extraction pipeline and flow simulations can be obtained from the following publications:<br></strong>P. Eulzer, F. von Deylen, W.-C. Hsu, R. Wickenhöfer, C. M. Klingner, and K. Lawonn (2023), A Fully Integrated Pipeline for Visual Carotid Morphology Analysis. Computer Graphics Forum, 42(3): 25-37. <a href="https://doi.org/10.1111/cgf.14808">https://doi.org/10.1111/cgf.14808</a></p> <p>Kevin Richter, Tristan Probst, Anna Hundertmark, Pepe Eulzer, and Kai Lawonn (2024), Longitudinal wall shear stress evaluation using centerline projection approach in the numerical simulations of the patient-based carotid artery. Computer Methods in Biomechanics and Biomedical Engineering, 27(3): 347-364. <a href="https://doi.org/10.1080/10255842.2023.2185478">https://doi.org/10.1080/10255842.2023.2185478</a></p> <p>P. Eulzer, K. Richter, A. Hundertmark, R. Wickenhöfer, C. M. Klingner, and K. Lawonn (2024), Instantaneous Visual Analysis of Blood Flow in Stenoses Using Morphological Similarity. Computer Graphics Forum 43(3): in print. <a href="https://doi.org/10.1111/cgf.15081">https://doi.org/10.1111/cgf.15081</a></p>
Hemodynamic, ventilatory and respiratory mechanics variables of children with respiratory failure before and after the use of the Bag Squeezing maneuver.
<p><span><span>Tabela com variáveis hemodinâmicas ventilatórias e mecânica respiratória de crianças com insuficiência respiratória</span></span></p>
Hemodynamic data from the Inspired Therapeutics NeoMate Mechanical Circulatory Support System for neonates and infants as tested in static mock circulatory loops, dynamic mock circulatory loops, and acute animal studies
<p>Inspired Therapeutics (Merritt Island, FL) is developing a mechanical circulatory support (MCS) system designed as a single driver with interchangeable, extracorporeal, magnetically levitated pumps. The NeoMate system design features an integrated centrifugal rotary pump, motor, and controller that will be housed in a single compact unit. Conceptually, the primary innovation of this technology will be the combination of disposable, low-cost pumps for use with a single, multi-functional, universal controller to support multiple pediatric cardiopulmonary indications. In response to the paucity of clinically available pediatric devices, Inspired Therapeutics is specifically targeting the underserved neonate and infant heart failure (HF) patient population first. In this article, we present the development of the prototype Inspired Therapeutics NeoMate System for pediatric left ventricular assist device (LVAD) support, and feasibility testing in static mock flow loops (H-Q curves), dynamic mock flow loops (hemodynamics), and in an acute healthy ovine model (hemodynamics and clinical applicability). The resultant hydrodynamic and hemodynamic data demonstrated the ability of this prototype pediatric LVAD and universal controller to function over a range of rotary pump speeds (500-6000 RPM), to provide pump flow rates of up to 2.6 L/min, and to volume unload the left ventricle in acute animals. Key engineering challenges observed and proposed solutions for the next design iteration are also presented.</p>
Dataset for the article : Non-invasive estimation of in vivo optical properties and hemodynamic parameters of domestic animals: a preliminary study on horses, dogs, and sheep
<div> <div> <div> <div> </div> </div> </div> </div> <div> <div> <div> <div> <div> <div> <p>This dataset includes all the necessary data to understand and replicate the figures and tables presented in the article titled "Non-invasive Estimation of In Vivo Optical Properties and Hemodynamic Parameters of Domestic Animals: A Preliminary Study on Horses, Dogs, and Sheep." Specifically, it contains the raw measurement curves, along with the optical and hemodynamic parameters derived from the analysis of these raw data.</p> </div> </div> </div> </div> </div> </div>
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.