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623
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Dataset results
623 results for “hormonal therapy”
Use of Low Dose Ketoconazole in Prostate Cancer That Does Not Respond to Hormone Therapy and Prior Chemotherapy
ClinicalTrials.gov study NCT00895310. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Growth Hormone Therapy in Osteogenesis Imperfecta
ClinicalTrials.gov study NCT00001305. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Assessment of the Transfer of Using Levonorgestrel Intrauterine System (LNG IUS) as a Contraceptive to Using it as Part of Hormone Replacement Therapy (HRT).
ClinicalTrials.gov study NCT00185458. IPD Sharing: Not stated. Countries: 4. Publications: 1.
Data from: Systemic thyroid hormone status during levothyroxine therapy in hypothyroidism: a systematic review and meta-analysis
CONTEXT: The standard of care for overt hypothyroidism is levothyroxine at doses that normalize serum TSH levels. Whether this approach universally restores thyroid hormone signaling is unknown. OBJECTIVE: To review studies of overt hypothyroidism in which participants were treated with levothyroxine to normalize serum TSH levels and measured other objective markers of thyroid hormone signaling. DESIGN: Databases were searched for studies that reported objective markers of thyroid hormone signaling (serum low-density lipoprotein (LDL), total cholesterol (TC), sex hormone-binding globulin (SHBG), creatine kinase and/or ferritin levels; cognition, energy expenditure, and/or renal function) in levothyroxine monotherapy for overt, primary hypothyroidism among nonpregnant adults with normal serum TSH levels. For studies with LDL, TC and SHBG outcomes, data were pooled using random effects meta-analysis. RESULTS: A total of 99 studies met inclusion criteria, including 65 that reported serum cholesterol data. Meta-analysis showed that levothyroxine-treated hypothyroid participants with normal serum TSH levels had 3.31 ± 1.64 mg/dL higher serum LDL levels (p=0.044) and 9.60 ± 3.55 mg/dL higher serum TC levels (p=0.007) compared to controls. In studies that did not concomitantly assess healthy controls, serum LDL levels were 138.3 ± 4.6 mg/dL (p<0.001) and serum TC levels were 209.6 ± 3.4 mg/dL (p<0.001). Meta-analysis of 2 studies showed no significant difference between SHBG levels of levothyroxine-treated participants and controls. CONCLUSIONS: In studies that utilized levothyroxine monotherapy at doses that normalized the serum TSH for overt, primary hypothyroidism, not all systemic biological markers of thyroid hormone signaling were normalized, including serum LDL and TC levels.
Hormone Sensitive Prostate Cancer Patients Switched to Degarelix Therapy After Failing on GnRH Agonists
ClinicalTrials.gov study NCT01366053. IPD Sharing: UNDECIDED. Countries: 1. Publications: 7.
HumanaH - Hu3s193 in the Treatment of Advanced Breast Cancer After Hormonal Therapy
ClinicalTrials.gov study NCT01370239. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Arsenic Trioxide in Treating Patients With Stage IV Prostate Cancer That Has Not Responded to Previous Hormone Therapy
ClinicalTrials.gov study NCT00004149. IPD Sharing: Not stated. Countries: 1. Publications: 0.
PROSTVAC®-VF/TRICOM™ Vaccine for the Treatment of Metastatic Prostate Cancer After Failing Hormone Therapy
ClinicalTrials.gov study NCT00078585. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Anti-hormonal Therapie With Ribociclib in HR-positive / HER2- Negative Metastatic Breast Cancer
ClinicalTrials.gov study NCT03555877. IPD Sharing: NO. Countries: 1. Publications: 2.
Cognitive Function in Older Women With Stage I, Stage II, or Stage III Breast Cancer Receiving Hormone Therapy
ClinicalTrials.gov study NCT00681928. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Women With Breast Cancer Who Are Having Hormone Therapy
ClinicalTrials.gov study NCT06440967. IPD Sharing: YES. Countries: 11. Publications: 1.
Estramustine, Docetaxel, and Carboplatin in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy
ClinicalTrials.gov study NCT00005627. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effect of Hormone Therapy on Renal Function
ClinicalTrials.gov study NCT04482920. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Capecitabine or Endocrinotherapy as a Maintenance Therapy Regimen at Least 2nd Line in Hormone Receptor Positive and HER2 Negative Metastatic Breast Cancer
ClinicalTrials.gov study NCT03204734. IPD Sharing: NO. Countries: 1. Publications: 1.
St. John's Wort in Relieving Fatigue in Patients Undergoing Chemotherapy or Hormone Therapy for Cancer
ClinicalTrials.gov study NCT00005805. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Hormone Therapy in Treating Postmenopausal Women With Receptor-Positive Breast Cancer
ClinicalTrials.gov study NCT00002646. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Anlotinib-based Combination Therapy in Patients with Hormone Receptor-positive（HR+） Metastatic Breast Cancer(MBC) .
ClinicalTrials.gov study NCT06734533. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Endocrine Therapy Plus CDK4/6 in First or Second Line for Hormone (SONIA) Receptor Positive Advanced Breast Cancer
ClinicalTrials.gov study NCT03425838. IPD Sharing: NO. Countries: 1. Publications: 4.
Cross-sex Hormone Therapy and Neuronal Plasticity
ClinicalTrials.gov study NCT03651427. IPD Sharing: NO. Countries: 1. Publications: 1.
Descriptive Analysis of Clinical Outcomes in Patients With Prostate Gland Cancer, Which Spreads to Other Parts of the Body, Who Were Treated First With Novel Anti-hormone Therapy Followed by a Second
ClinicalTrials.gov study NCT03896984. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.