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153
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ShareScore release 0.9.0
Dataset results
153 results for “hypertonic saline”
The Use of a Restrictive Fluid Regimen With Hypertonic Saline for Patients Undergoing Pancreaticoduodenectomy
ClinicalTrials.gov study NCT01428050. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efficacy Of Combined Nebulized Hypertonic Saline and Chest Percussion Therapy in Acute Viral Bronchiolitis
ClinicalTrials.gov study NCT06441162. IPD Sharing: YES. Countries: 1. Publications: 0.
Hypertonic Saline as Add on Therapy in Preschool Children With Acute Wheezing Attack.
ClinicalTrials.gov study NCT01073527. IPD Sharing: Not stated. Countries: 1. Publications: 1.
High Flow Therapy vs Hypertonic Saline in Bronchiolitis
ClinicalTrials.gov study NCT01873144. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Assessment of Circulating Copeptin Levels in Healthy Subjects and Patients With Renal Insufficiency After Oral Water Load and Hypertonic Saline Infusion
ClinicalTrials.gov study NCT00696605. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Nebulised 3% Hypertonic Saline Versus 0.9% Saline for Treating Patients Hospitalized With Acute Bronchiolitis
ClinicalTrials.gov study NCT06069336. IPD Sharing: YES. Countries: 1. Publications: 1.
The Effects of Isotonic and Hypertonic Saline Infusion on Renal Biomarkers in Healthy Young Subjects
ClinicalTrials.gov study NCT01414088. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Furosemide Alone or Unexpectedly With Solution of Hypertonic Saline in Nephrotic Syndrome
ClinicalTrials.gov study NCT03750136. IPD Sharing: YES. Countries: 1. Publications: 3.
Hypertonic Saline Solution in Heart Failure
ClinicalTrials.gov study NCT00555685. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Nebulized 3% Hypertonic Saline vs. Standard of Care in Patients With Bronchiolitis
ClinicalTrials.gov study NCT02834819. IPD Sharing: UNDECIDED. Countries: 0. Publications: 10.
Hypertonic Saline-hetastarch in Cardiac Surgery
ClinicalTrials.gov study NCT00469716. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Data from: Stratified assessment of the role of inhaled hypertonic saline in reducing cystic fibrosis pulmonary exacerbations: a retrospective analysis
Objective: Limited data exist concerning the role of inhaled hypertonic saline (HS) in decreasing pulmonary exacerbations in cystic fibrosis (CF), especially as more advanced stages of CF lung disease were excluded in prior studies. Herein we retrospectively determined the efficacy of inhaled HS in reducing CF pulmonary exacerbations when stratified according to the severity of CF lung disease. Stratification was based on the framework of the Pulmonary Therapeutics Committee's published gradation of obstructive lung physiology in CF, i.e., mild (FEV1 > 70%), moderate (FEV1 40-70%) and severe (FEV1 < 40%) lung disease, respectively. Design: A retrospective review of the Port CF® database over a 3-year period performed at an academic CF care center. Results: 340 pulmonary exacerbations were identified; inhaled HS was being used in 99 of these cases. Univariate analysis demonstrated a significant reduction in pulmonary exacerbations only in mild obstruction (OR=0.09, CI 0.01-0.81, p=0.012); however, multivariate logistic regression that adjusted for confounding variables showed a reduction in pulmonary exacerbations across the entire spectrum of obstructive lung disease when using inhaled HS i.e., mild obstructive CF lung disease (OR=0.17, CI 0.05-0.58, p=0.004), moderate obstructive CF lung disease (OR=0.39, CI 0.16-0.93, p=0.034), as well as severe obstructive CF lung disease (OR=0.02, CI 0.001-0.45, p=0.015). Moreover, inhaled HS appeared reasonably well tolerated across all stages of lung disease severity, and was discontinued in only 7% of cases (n=4) with severe lung disease. Conclusion: In this study, inhaled HS appeared to reduce pulmonary exacerbations in CF lung disease at all stages of obstruction. This underscores the importance of therapeutic inhaled HS in CF lung disease, regardless of severity of lung obstruction.
Nebulized 3% Hypertonic Saline in the Treatment of Acute Bronchiolitis
ClinicalTrials.gov study NCT02029040. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Comparison of Hypertonic Saline and Mannitol on Brain Relaxation During Supratentorial Tumors Resection
ClinicalTrials.gov study NCT04314674. IPD Sharing: NO. Countries: 0. Publications: 3.
Impact of Discontinuing Hypertonic Saline in People With CF on Highly Effective CFTR Modulators- A SIMPLIFY Sub-Study
ClinicalTrials.gov study NCT06350461. IPD Sharing: NO. Countries: 1. Publications: 0.
Effectiveness and Safety of Inhaling Hypertonic Saline in Patients With Chronic Obstructive Pulmonary Disease
ClinicalTrials.gov study NCT00639236. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Tolerability of Hypertonic Saline in Infants With Cystic Fibrosis
ClinicalTrials.gov study NCT00753987. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Effects of Long Term Inhalation of Hypertonic Saline in Subjects With Cystic Fibrosis
ClinicalTrials.gov study NCT00271310. IPD Sharing: Not stated. Countries: 0. Publications: 2.
Nebulized Hypertonic Saline for Inpatient Use in COPD
ClinicalTrials.gov study NCT02266875. IPD Sharing: NO. Countries: 1. Publications: 0.
Hypertonic Saline Nasal Irrigation and Gargling in Suspected or Confirmed COVID-19 (ELVIS COVID-19)
ClinicalTrials.gov study NCT04382131. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
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