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622 results for “macaques”
Crab Eating Macaque SNP Calls VCF
<p>Bgzipped vcf and tabix index files of crab eating macaque SNP calls of 26 individuals on the macFas5 assembly.</p>
Rhesus Macaque SNP Calls VCF
<p>Bgzipped vcf and tabix index files of rhesus macaque SNP calls of 526 individuals on the rheMac8 assembly.</p>
Plate 1 in Population status and distribution assessment of Nicobar Long-Tailed Macaque Macaca Fascicularis Umbrosus (Miller, 1902) in Nicobar Group of Islands
Plate 1. Nicobar Long tailed Macaque in its natural forested habitat.
Fig. 2 in Gastro-intestinal parasites of urban rhesus macaques (Macaca mulatta) in the Kathmandu Valley, Nepal
Fig. 2. Prevalence of gastro-intestinal parasites in the rhesus macaques of Kathmandu Valley.
Fig. 4 in Gastro-intestinal parasites of urban rhesus macaques (Macaca mulatta) in the Kathmandu Valley, Nepal
Fig. 4. Location-wise richness of parasitic infection in rhesus macaques of the Kathmandu Valley.
Fig. 5 in Gastro-intestinal parasites of urban rhesus macaques (Macaca mulatta) in the Kathmandu Valley, Nepal
Fig. 5. Species Richness of GI parasite infection in rhesus macaques of the Kathmandu Valley.
Fig. 1 in Prevalence and new genotypes of Enterocytozoon bieneusi in wild rhesus macaque (Macaca mulatta) in China: A zoonotic concern
Fig. 1. Specific locations at which specimens were collected in this study.
Population Dynamics of a Subpopulation of Lion-tailed Macaques in a Rainforest Fragment, in the southern Western Ghats of India
<p>The dataset includes absolute group counts of five groups of lion-tailed macaques inhabiting the Puthuthottam forest fragment of Valparai, Tamil Nadu, India. The counts were conducted over a period of three years between 2018-2020 at six-monthly intervals. </p>
Connectional asymmetry of the inferior parietal lobule shapes hemispheric specialization in humans, chimpanzees, and rhesus macaques
<p>The inferior parietal lobule (IPL) is one of the most expanded cortical regions in humans relative to other primates. It is also among the most structurally and functionally asymmetric regions in the human cerebral cortex. Whether the structural and connectional asymmetries of IPL subdivisions differ across primate species and how this relates to functional asymmetries remain unclear. We identified IPL subregions that exhibited positive allometric in both hemispheres, scaling across rhesus macaque monkeys, chimpanzees, and humans. The patterns of IPL subregions asymmetry were similar in chimpanzees and humans, but no IPL asymmetries were evident in macaques. Among the comparative sample of primates, humans showed the most widespread asymmetric connections in the frontal, parietal, and temporal cortices, constituting leftward asymmetric networks that may provide an anatomical basis for language and tool use. Unique human asymmetric connectivity between the IPL and primary motor cortex might be related to handedness. These findings suggest that structural and connectional asymmetries may underlie hemispheric specialization of the human brain.</p>
Use of the Animal Welfare Assessment Grid to monitor the ef-fects of enrichment on macaque welfare.
<p>The data pubished relates to a research project that was undertaken to identify the effect of novel enrichments on the welfare of rhesus macaques housed in a breeding facility in the UK. </p>
Female Assamese macaques bias their affiliation to paternal and maternal kin
<p>Forming strong social bonds can lead to higher reproductive success, increased longevity and/or increased infant survival in several mammal species. Given these adaptive benefits, understanding what determines partner preferences in social bonding is important. Maternal relatedness strongly predicts partner preference across many mammalian taxa. The role of paternal relatedness, however, has received relatively little attention, even though paternal and maternal kin share the same number of genes, and theoretically similar preferences would therefore be expected for paternal kin. Here, we investigate the role of maternal and paternal relatedness in female affiliation in Assamese macaques (<i>Macaca assamensis</i>), a species characterized by a relatively low male reproductive skew. We studied a wild population under natural conditions using extensive behavioral data and relatedness analyses based on pedigree reconstruction. We found stronger affiliative relationships and more time spent grooming between maternal kin and paternal half-sisters compared to non-kin, with no preference of maternal over paternal kin. Paternally related and non-related dyads did not form stronger relationships when they had less close maternal kin available, but we would need a bigger sample size to confirm this. As expected given the low reproductive skew, affiliative relationships between paternal half-sisters closer in age were not stronger than between paternal half-sisters with larger age differences, suggesting that the kin bias towards paternal kin was not mediated by age similarity. An alternative way through which paternal kin could get familiarized is mother- and/or father-mediated familiarity.</p>
Mitonuclear interactions and introgression genomics of macaque monkeys (Macaca) highlight the influence of behaviour on genome evolution
<p>In most macaques, females are philopatric and males migrate from their natal ranges, which results in pronounced divergence of mitochondrial genomes within and among species. We therefore predicted that some nuclear genes would have to acquire compensatory mutations to preserve compatibility with diverged interaction partners from the mitochondria. We additionally expected that these sex-differences would have distinctive effects on gene flow in the X and autosomes. Using new genomic data from 29 individuals from eight species of Southeast Asian macaque, we identified evidence of natural selection associated with mitonuclear interactions, including extreme outliers of interspecies differentiation and metrics of positive selection, low intraspecies polymorphism, and atypically long runs of homozygosity associated with nuclear-encoded genes that interact with mitochondria-encoded genes. In one individual with introgressed mitochondria, we detected a small but significant enrichment of autosomal introgression blocks from the source species of her mitochondria that contained genes that interact with mitochondria-encoded loci. Our analyses also demonstrate that sex-specific demography sculpts genetic exchange across multiple species boundaries. These findings show that behaviour can have profound but indirect effects on genome evolution by influencing how interacting components of different genomic compartments (mitochondria, the autosomes, the sex chromosomes) move through time and space.</p>
Functional interactions among neurons within single columns of macaque V1
<p>Recent developments in high-density neurophysiological tools now make it possible to record from hundreds of single neurons within local, highly interconnected neural networks. Among the many advantages of such recordings is that they dramatically increase the quantity of identifiable, functional interactions between neurons thereby providing an unprecedented view of local circuits. Using high-density, Neuropixels recordings from single neocortical columns of primary visual cortex in nonhuman primates, we identified 1000s of functionally interacting neuronal pairs using established crosscorrelation approaches. Our results reveal clear and systematic variations in the synchrony and strength of functional interactions within single cortical columns. Despite neurons residing within the same column, both measures of interactions depended heavily on the vertical distance separating neuronal pairs, as well as on the similarity of stimulus tuning. In addition, we leveraged the statistical power afforded by the large numbers of functionally interacting pairs to categorize interactions between neurons based on their crosscorrelation functions. These analyses identified distinct, putative classes of functional interactions within the full population. These classes of functional interactions were corroborated by their unique distributions across defined laminar compartments and were consistent with known properties of V1 cortical circuitry, such as the lead-lag relationship between simple and complex cells. Our results provide a clear proof-of-principle for the use of high-density neurophysiological recordings to assess circuit-level interactions within local neuronal networks.</p>
Propagating spatio-temporal activity patterns across macaque motor cortex carry kinematic information
<p>Propagating spatio-temporal neural patterns are widely evident across sensory, motor and association cortical areas. However, it remains unclear whether any characteristics of neural propagation carry information about specific behavioral details. Here, we provide the first evidence for a link between the direction of cortical propagation and specific behavioral features of an upcoming movement on a trial-by-trial basis. We recorded local field potentials (LFPs) from multi-electrode arrays implanted in the primary motor cortex of two rhesus macaque monkeys while they performed a 2-D reach task. Propagating patterns were extracted from the information-rich high-gamma band (200–400Hz) envelopes in the LFP amplitude. We found that the exact direction of propagating patterns varied systematically according to initial movement direction, enabling kinematic predictions. Furthermore, characteristics of these propagation patterns provided additional predictive capability beyond the LFP amplitude themselves, which suggests the value of including mesoscopic spatio-temporal characteristics in refining brain-machine interfaces.</p>
Data from: Social disappointment and partner presence affect long-tailed macaque refusal behaviour in an "inequity aversion" experiment
<p><span>Protest in response to unequal reward distribution is thought to have played a central role in the evolution of human cooperation. Some animals refuse food and become demotivated when rewarded more poorly than a conspecific, and this has been taken as evidence that non-human animals, like humans, protest in the face of inequity. An alternative explanation - social disappointment – shifts the cause of this discontent away from the unequal reward, to the human experimenter who could – but elects not to – treat the subject well. This study investigates whether social disappointment could explain frustration behaviour in long-tailed macaques, <em>Macaca</em> <em>fascicularis</em>. We tested 12 monkeys in a novel `inequity aversion' paradigm. Subjects had to pull a lever and were rewarded with low-value food; in half of the trials, a partner worked alongside the subjects receiving high-value food. Rewards were distributed either by a human or a machine. In line with the social disappointment hypothesis, monkeys rewarded by the human refused food more often than monkeys rewarded by the machine. </span>Our study extends previous findings in chimpanzees and suggests that social disappointment plus social facilitation or food competition effects drive food refusal patterns.</p>
Calorie restriction and pravastatin administration during pregnancy in obese rhesus macaques modulates maternal and infant metabolism and infant brain and behavioral development
<p>Maternal obesity has been associated with a higher risk of pregnancy-related complications in mothers and offspring; however, effective interventions have not yet been developed. We tested two common interventions, calorie restriction and pravastatin administration, during pregnancy in a rhesus macaque model with the hypothesis that these interventions would normalize metabolic dysregulation in pregnant mothers leading to an improvement in infant metabolic and cognitive/social development. A total of 19 obese mothers were assigned to either one of the two intervention groups (n=5 for calorie restriction; n=7 for pravastatin) or an obese control group (n=7) with no intervention, and maternal gestational samples and postnatal infant samples were compared with lean control mothers (n=6). Gestational calorie restriction normalized one-carbon metabolism dysregulation in obese mothers but altered energy metabolism in their offspring. Although administration of pravastatin during pregnancy tended to normalize blood cholesterol in the mothers, it potentially impacted the gut microbiome and kidney function of their offspring. In the offspring, both calorie restriction and pravastatin administration during pregnancy tended to normalize the activity of AMPK in the brain at 6 months, and while results of the Visual Paired-Comparison test, which measures infant recognition memory, were not significantly impacted by either of the interventions, gestational pravastatin administration, but not calorie restriction, tended to normalize anxiety assessed by the Human Intruder test. Although the two interventions tested in a non-human primate model led to some improvements in metabolism and/or infant brain development, negative impacts were also found in both mothers and infants. Our study emphasizes the importance of assessing gestational interventions for maternal obesity on both maternal and offspring long-term outcomes.</p>
Hemostasis defects underlying the hemorrhagic syndrome caused by Mammarenaviruses in a cynomolgus macaque model
<p>Abstract: Viral hemorrhagic fevers (HF) are a group of acute febrile diseases with high mortality rates. While hemostatic dysfunction appears to be a major determinant of the severity of the disease, it is still unclear what pathogenic mechanisms lead to it. In clinical studies, arenaviruses such as Lassa, Machupo and Guanarito viruses caused HF that vary in symptoms and biological alterations.</p> <p>In this study we aimed to characterize the hemostatic dysfunction induced by arenaviral HF to determine its implication in the severity of the disease and to elucidate the origin of this syndrome.</p> <p>We found that lethal infection with Machupo, Guanarito and Lassa viruses is associated with cutaneo-mucosal, cerebral, digestive and pulmonary hemorrhages. The affected animals developed a severe alteration of the coagulation system, which was concomitant with acute hepatitis, minor deficit of hepatic factor synthesis, presence of a plasmatic inhibitor of coagulation and dysfunction of the fibrinolytic system. Despite signs of increased vascular permeability, endothelial cell infection was not a determinant factor of the hemorrhagic syndrome. There were also alterations of the primary hemostasis during lethal infection, with moderate to severe thrombocytopenia and platelet dysfunction. Finally, we show that lethal infection is accompanied by a reduced hematopoietic potential of the bone marrow. This study provides an unprecedented characterization of the hemostasis defects induced by several highly pathogenic Arenaviruses.</p> <p>Transcriptomics data presented in Figure 3 and in Supp Figure 2</p>
Data associated with Vandeleest, Beisner et al. (PeerJ, 2016) "Decoupling Social Status and Status Certainty Effects on Health in Macaques: A Network Approach"
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Data associated with Vandeleest, Beisner et al. (PeerJ, 2016) "Decoupling Social Status and Status Certainty Effects on Health in Macaques: A Network Approach"
Open the record for dataset details and reuse information.
Multi-omic brain and behavioral correlates of cell-free fetal DNA methylation in macaque maternal obesity models (GC-FID dataset infant brains)
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.