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97 results for “mathematical modelling”

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dryad32/100

Data from: Strategies for understanding and reducing the Plasmodium vivax and Plasmodium ovale hypnozoite reservoir in Papua New Guinean children: a randomised placebo-controlled trial and mathematical model

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publicSep 2016View details →
dryad28/100

Data from: A mathematical model of marine bacteriophage evolution

To explore how particularities of a cell-virus system affects viral evolution, we formulate a mathematical model of marine bacteriophage evolution. The intrinsic simplicity of real-life phage-bacteria systems allows to have a reasonably simple model. The model constructed in this paper is based upon Beretta-Kuang model of bacteria-phage interaction. Compared to the Beretta-Kuang model, the model assumes the existence of a multitude of viral variants which correspond to continuously distributed phenotypes. It is noteworthy that this model does not include any explicit law or mechanism of evolution; instead it is assumed, in agreement to the principles of Darwinian evolution, that evolution in this system can occur as a result of random mutations and natural selection. Simulations with a leaner fitness landscape (which is chosen for the convenience of demonstration only) show that a pulse-type traveling wave moving towards increasing Darwinian fitness appears in the phenotype space. This implies that the overall fitness of a viral quasispecies steadily increasing in time. That is, the simulations demonstrate that for an uneven fitness landscape random mutations combined with a mechanism of natural selection lead to the Darwinian evolution. It is noteworthy that in this system the speed of propagation of this wave (and hence the rate of evolution) is not constant but varies, depending on the current viral fitness and the abundance of susceptible bacteria.

opencc-zeroDec 2017View details →
dryad28/100

Data from: Mathematical modelling of the vitamin C clock reaction

Chemical clock reactions are characterised by a relatively long induction period followed by a rapid `switchover' during which the concentration of a \emph{clock chemical} rises rapidly. In addition to their interest in chemistry education, these reactions are relevant to industrial and biochemical applications. A substrate-depletive, non-autocatalytic clock reaction involving household chemicals (vitamin C, iodine, hydrogen peroxide and starch) is modelled mathematically via a system of nonlinear ordinary differential equations. Following dimensional analysis the model is analysed in the phase plane and via matched asymptotic expansions. Asymptotic approximations are found to agree closely with numerical solutions in the appropriate time regions. Asymptotic analysis also yields an approximate formula for the dependence of switchover time on initial concentrations and the rate of the slow reaction. This formula is tested via `kitchen sink chemistry' experiments, and is found to enable a good fit to experimental series varying in initial concentrations of both iodine and vitamin C. The vitamin C clock reaction provides an accessible model system for mathematical chemistry.

opencc-zeroDec 2018View details →
dryad28/100

Data from: Differential chromosome conformations as hallmarks of cellular identity revealed by mathematical polymer modeling

Inherently dynamic, chromosomes adopt many different conformations in response to DNA metabolism. Models of chromosome organization in the yeast nucleus obtained from genome-wide chromosome conformation data or biophysical simulations provide important insights into the average behavior but fail to reveal features from dynamic or transient events that are only visible in a fraction of cells at any given moment. We developed a method to determine chromosome conformation from relative positions of three fluorescently tagged DNA in living cells imaged in 3D. Cell type specific chromosome folding properties could be assigned based on positional combinations between three loci on yeast chromosome 3. We determined that the shorter left arm of chromosome 3 is extended in MATα cells, but can be crumpled in MATa cells. Furthermore, we implemented a new mathematical model that provides for the first time an estimate of the relative physical constraint of three linked loci related to cellular identity. Variations in this estimate allowed us to predict functional consequences from chromatin structural alterations in asf1 and recombination enhancer deletion mutant cells. The computational method is applicable to identify and characterize dynamic chromosome conformations in any cell type.

opencc-zeroDec 2014View details →
dryad28/100

Data from: Data-driven mathematical model of East-Asian facial attractiveness: the relative contributions of shape and reflectance to attractiveness judgements

Facial attractiveness is judged through a combination of multiple cues including morphology (facial shape) and skin properties (facial reflectance). While several studies have examined the way in which people in Western cultures judge facial attractiveness, there have been fewer investigations into non-Western attitudes. This is because stimuli that quantitatively vary the attractiveness of non-Western faces are rare. In the present study, we built a model of the attractiveness of East-Asian faces, judged by East-Asian observers. Therefore, 400 computer-generated East-Asian faces were created and attractiveness rating scores were collected from Japanese observers. Data-driven mathematical calculations were used to identify quantitative links between facial attractiveness and shape and reflectance properties, with no prior hypothesis. Results indicate that faces with larger eyes, smaller noses, and brighter skin are judged as more attractive, regardless of the sex of the faces, possibly reflecting a general preference for femininity. Shape is shown to be a strong determinant of attractiveness for both male and female faces, while reflectance properties are less important in judging male facial attractiveness. Our model provides a tool to effectively produce East-Asian face stimuli that quantitatively varies attractiveness and can be used to elucidate visual processes related to attractiveness judgment.

opencc-zeroDec 2018View details →
zenodo28/100

MATHEMATICAL AND PHYSICAL MODELING FORECASTING IN MEDICINE

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opencc-by-4.0Nov 2023View details →
zenodo28/100

Calibrated Mathematical Programming Models In Agriculture: A Systematic and Bibliometric Review

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opencc-by-4.0Apr 2024View details →
ClinicalTrials.gov28/100

Study of Biweekly Capecitabine Dosing With Bevacizumab for the Treatment of Metastatic Breast Cancer Based Upon the Norton-Simon Mathematical Model

ClinicalTrials.gov study NCT00468585. IPD Sharing: Not stated. Countries: 1. Publications: 0.

restrictedIPD-UNDECIDEDFeb 2026View details →
dryad28/100

Data from: A mathematical model of cocoa bean fermentation

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publicSep 2018View details →
dryad28/100

Data from: A comprehensive mathematical model of motor unit pool organization, surface electromyography and force generation

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publicMar 2019View details →
dryad28/100

Data from: Mathematical modelling of the vitamin C clock reaction

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publicMar 2019View details →
dryad28/100

Data from: Data-driven mathematical model of East-Asian facial attractiveness: the relative contributions of shape and reflectance to attractiveness judgements

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publicMay 2019View details →
dryad28/100

Data from: The role of geospatial hotspots in the spatial spread of tuberculosis in rural Ethiopia: a mathematical modelling

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publicSep 2018View details →
dryad28/100

Data from: A mathematical model of marine bacteriophage evolution

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publicFeb 2018View details →
dryad28/100

Data from: Within-host mathematical modelling of the incubation period of Salmonella Typhi

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publicAug 2019View details →
dryad28/100

Data from: Differential chromosome conformations as hallmarks of cellular identity revealed by mathematical polymer modeling

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publicMay 2016View details →
dryad28/100

Data from: A clinically parameterized mathematical model of Shigella immunity to inform vaccine design

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publicDec 2018View details →
dryad28/100

A mathematical model of flow-mediated coagulation identifies factor V as a modifier of thrombin generation in hemophilia A

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publicJan 2019View details →
zenodo24/100

The Unified Geometric Wave Theory: Updated Summary and mathematical model and process

<p>The Unified Geometric Wave Theory (UGWT) proposes that the universe's fundamental interactions are interconnected through waves, vibrations, and frequencies. This theory integrates concepts from quantum mechanics, general relativity, and sacred geometry, aiming to bridge the gap between quantum phenomena and macroscopic gravitational effects. The UGWT is currently in the empirical validation stage and seeks peer review for further refinement.</p>

embargoedcc-by-4.0Jul 2024View details →
ClinicalTrials.gov24/100

Mathematical Modeling of the Acute Inflammatory Response Following Injury

ClinicalTrials.gov study NCT00250523. IPD Sharing: NO. Countries: 1. Publications: 0.

closedIPD-NOFeb 2026View details →

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Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record