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2,576 results for “pet”
Amyloid burden quantification depends on PET and MR image processing methodology
<p>The enclosed datasets refer to the work developed at the University Medical Center Groningen and consist of the minimally required PET image data to replicate the results of the study entitled "Amyloid burden quantification depends on PET and MR image processing methodology" which abstract can be found below:</p> <blockquote> <p>Quantification of amyloid load with positron emission tomography can be useful to assess Alzheimer’s Disease <em>in-vivo. </em>However, quantification can be affected by the image processing methodology applied. This study’s goal was to address how amyloid quantification is influenced by different semi-automatic image processing pipelines. Images were analysed in their <em>Native Space </em>and <em>Standard Space</em>; non-rigid spatial transformation methods based on maximum a posteriori approaches and tissue probability maps (TPM) for regularisation were explored. Furthermore, grey matter tissue segmentations were defined before and after spatial normalisation, and also using a population-based template. Five quantification metrics were analysed: two intensity-based, two volumetric-based, and one multi-parametric feature.</p> <p>Intensity-related metrics were not meaningfully affected by spatial normalisation and did not significantly depend on the grey matter segmentation method, with an impact similar to that expected from test-retest studies (≤10%). Yet, volumetric and multi-parametric features were sensitive to the image processing methodology, with an overall variability up to 45%. Therefore, the analysis should be carried out in <em>Native Space</em> avoiding non-rigid spatial transformations. For analyses in <em>Standard Space</em>, spatial normalisation regularised by TPM is preferred. Volumetric-based measurements should be done in <em>Native Space,</em> while intensity-based metrics are more robust against differences in image processing pipelines.</p> </blockquote>
First detection of herpesvirus and mycoplasma in free-ranging Hermann's tortoises (Testudo hermanni), and in potential pet vectors
<p>Two types of pathogens cause highly contagious upper respiratory tract diseases (URTD) in Chelonians: testudinid herpesviruses (TeHV) and a mycoplasma (<em>Mycoplasma agassizii</em>). In captivity, these infections are frequent and can provoke outbreaks. Pet trade generates international flow of tortoises, often without sanitary checking; individuals intentionally or accidentally released in the wild may spread pathogens. A better understanding of the transmission of infectious agents from captivity to wild tortoises is needed. Many exotic individuals have been introduced in populations of the endangered western Hermann’s tortoise (<em>Testudo hermanni hermanni</em>), notably spur-thighed tortoises (<em>Testudo graeca</em>). We assessed the presence of TeHV and mycoplasma in native western Hermann’s tortoises and in potential pet vectors in south-eastern France. Using a large sample (N=572 tortoises), this study revealed the worrying presence of herpesvirus in 7 free-ranging individuals (3 sub-populations). Additionally, <em>Mycoplasma agassizii</em> was detected in 15 of the 18 populations sampled with a frequency ranging from 2.5 to 25%. Exotic spur-thighed tortoises showed high frequency of <em>Mycoplasma </em>infection in captivity (18%) and in individuals (50%) found in native Hermann’s tortoise sub-populations, suggesting that this species could be a significant vector. The paucity of information of TeHV on European tortoise’ URTD in natural settings, especially in combination with mycoplasma, prompts for further studies. Indeed, sick tortoises remain concealed and may not be easily detected in the field. Our results indicate that both the prevalence and health impact of URTD are high should be scrutinized in the field.</p>
Impact of Image Processing Settings for Radiomic Features in Alzheimer's Disease Using 18F-FDG and 11C-PIB PET Scans
<p>Radiomics is an established method for calculating features for computer-aided diagnosis and has been vastly applied to oncological studies. This study aimed to assess the impact of image processing in radiomic features in neuroimaging. Fifteen Alzheimer's disease subjects and 18 healthy individuals underwent [18F]-2-fluoro-2-deoxy-D-glucose (FDG) and 11C-labelled Pittsburgh Compound B (PIB) PET scans. T1-MRI scans were used for cerebellar and grey matter (GM), and white matter (WM) tissue delineation. PET images were registered to MRI (MR space) and transformed to MNI space. All images were normalized to cerebellar uptake (SUVR). All possible combinations of the following settings were considered to extract feature values: (1)tracer: FDG or PIB; (2)space: MR or MNI space; (3)discretization: fixed bin number (BN) of 64, fixed bin sizes (BS) of 0.05 or 0.25; and (4)volume of interest (VOI): GM, WM, or BRAIN (GM+WM). Features that correlated (>0.9) to traditional metrics (average VOI SUVR and volume) in any configuration were removed. Correlation of feature values between configurations, redundancy, and harmonization of feature values were tested. Image processing settings highly affect radiomic feature values and should be carefully taken into consideration during study design and should be properly reported.</p><p> </p><p>The enclosed datasets refer to the work developed at the University Medical Center Groningen and consists of extracted feature values used in the publication.</p>
Files for MD simulation of the interaction between LCC-ICCG cutinase and PET polymer
<p>500 ns MD simulation of Cutinase adsorption onto the PET surface and cutinase in water.</p> <p>MD simulations were done using Gromacs package</p> <p>Force field:Charmm36</p>
Brown adipose tissue PET-MR after fructose and glucose intervention
<p>Includes the data and MATLAB functions used to produce the manuscript: "High-fructose feeding suppresses cold-stimulated brown adipose tissue glucose uptake in young men independently of changes in thermogenesis and the gut microbiome"</p>
Processed FDG-PET data from: A computational model of neurodegeneration in Alzheimer's disease
<p>Disruption of mental functions in Alzheimer's disease (AD) and related disorders is accompanied by selective degeneration of brain regions. These regions comprise large-scale ensembles of cells organized into systems for mental functioning, however the relationship between clinical symptoms of dementia, patterns of neurodegeneration, and functional systems is not clear. We developed a model of the association between dementia symptoms and degenerative brain anatomy using F18-fluorodeoxyglucose (FDG) PET and dimensionality reduction techniques patients with AD. This data and code package contains preprocessed FDG-PET images from 423 subjects across the Alzheimer's disease spectrum and the MATLAB code to produce eigenbrains from this data.</p>
Relationship Between Crystallization, Mechanical and Gas Barrier Properties of Poly(ethylene furanoate) (PEF) in Multinanolayered PLA-PEF and PET-PEF Films
<p>Alain Guinault, from CNAM, presented at the 24<sup>th</sup> International Conference on Material Forming (ESAFORM 2021) the results obtained and published in the framework of the project MyPack “Relationship Between Crystallization, Mechanical and Gas Barrier Properties of Poly(ethylene furanoate) (PEF) in Multinanolayered PLA-PEF and PET-PEF Films.”</p>
FlowNet-PET Test Sets
<p>The test sets utilized in our work on FlowNet-PET found in https://github.com/teaghan/FlowNet_PET</p>
FlowNet-PET Training Set
<p>The training set used for FlowNet-PET found in https://github.com/teaghan/FlowNet_PET</p> <p>A dataset of 300 phantoms generated using the 4D extended cardiac-torso (XCAT) anthropomorphic digital phantom (2x4x4) mm<sup>3</sup> voxels. The dataset is split into training (270) and validation (30) sets. For each phantom, ten frames spaced across a single breath cycle were created, each frame having (108x152x152) pixels resembling the activity distribution throughout the phantom. To emulate a simple representation of PET data acquisition, these distributions were used to sample a random number (between 1x10<sup>6</sup> and 9x10<sup>6</sup>) of counts per frame.<br> <br> The parameters for each XCAT phantom were varied randomly. This included the gender, axial section included, transaxial shifts, scaling factors in each direction, size and location of the lung lesion, extent of the diaphragm motion, extent of the chest expansion, and the activity of each organ.</p>
Reaction Mechanism of the PET Degrading Enzyme PETase Studied with DFT/MM Molecular Dynamics Simulations
<p>Raw simulations of the acylation step by PETase on a PET dimer model substrate, ran with CP2K 6.1 software at the PBE:AMBER level. Details can be found in the original manuscript (<a href="https://doi.org/10.1021/acscatal.1c03700">https://doi.org/10.1021/acscatal.1c03700</a>): Molecular topology in AMBER Parameter Topology format and Trajectories in CHARMM binary coordinate format DCD.</p> <p>RESIDUE LIST:<br> GLY57<br> TYR58<br> SER131<br> MET132<br> TRP156<br> ASP177<br> SER178<br> ILE179<br> ALA180<br> HID208<br> MOL262</p> <p>VMD selection:<br> (name CA C O HA2 HA3 and resname GLY and resid 57) or (name N CA CB H HA HB2 HB3 and resname TYR and resid 58) or (name CA C O OG CB HA HB2 HB3 HG and resname SER and resid 131) or (name N CA SD CE CB CG H HA HB2 HB3 HG2 HG3 HE1 HE2 HE3 and resname MET and resid 132) or (name CB CG CD1 CD2 CE2 CE3 NE1 CZ2 CZ3 CH2 HB2 HB3 HD1 HE1 HE3 HZ2 HZ3 HH2 and resname TRP and resid 156) or (name CG OD1 OD2 CB HB2 HB3 and resname ASP and resid 177) or (name C O and resname SER and resid 178) or (name N CA C O CG2 CD1 CB CG1 H HA HB HG12 HG13 HG21 HG22 HG23 HD11 HD12 HD13 and resname ILE and resid 179) or (name N CA H HA and resname ALA and resid 180) or (name CB CG CD2 ND1 CE1 NE2 HB2 HB3 HD1 HD2 HE1 and resname HID and resid 208) or (name C1 C10 C11 C12 C13 C14 C15 C16 C17 C18 C19 C2 C20 C3 C4 C5 C6 C7 C8 C9 H1 H10 H11 H12 H13 H14 H15 H16 H17 H2 H3 H4 H5 H6 H7 H8 H9 O1 O2 O3 O4 O5 O6 O7 O8 O9 and resname MOL and resid 262)</p> <p>PYMOL selection:<br> (name CA+C+O+HA2+HA3 & resn GLY & resi 57) | (name N+CA+CB+H+HA+HB2+HB3 & resn TYR & resi 58) | (name CA+C+O+OG+CB+HA+HB2+HB3+HG & resn SER & resi 131) | (name N+CA+SD+CE+CB+CG+H+HA+HB2+HB3+HG2+HG3+HE1+HE2+HE3 & resn MET & resi 132) | (name CB+CG+CD1+CD2+CE2+CE3+NE1+CZ2+CZ3+CH2+HB2+HB3+HD1+HE1+HE3+HZ2+HZ3+HH2 & resn TRP & resi 156) | (name CG+OD1+OD2+CB+HB2+HB3 & resn ASP & resi 177) | (name C+O & resn SER & resi 178) | (name N+CA+C+O+CG2+CD1+CB+CG1+H+HA+HB+HG12+HG13+HG21+HG22+HG23+HD11+HD12+HD13 & resn ILE & resi 179) | (name N+CA+H+HA & resn ALA & resi 180) | (name CB+CG+CD2+ND1+CE1+NE2+HB2+HB3+HD1+HD2+HE1 & resn HID & resi 208) | (name C1+C10+C11+C12+C13+C14+C15+C16+C17+C18+C19+C2+C20+C3+C4+C5+C6+C7+C8+C9+H1+H10+H11+H12+H13+H14+H15+H16+H17+H2+H3+H4+H5+H6+H7+H8+H9+O1+O2+O3+O4+O5+O6+O7+O8+O9 & resn MOL & resi 262)</p>
Pet van de Bergkapel Domaniale Mijn
Music was one of the many hobbies of the mine workers. Many mining companies had their own harmony or orchestra as a form to distract the miners during their freetime, to strenghten their communal bond, and to bring their families together. Each orchestra had its own uniform as a way of identification. This uniform cap belongs to the "Bergkapel" of the Domaniale Mijn from Kerkrade and it's made of fabric, plumes, and metallic badges. Height: 40cm Lenght: 16cm Width: 21cm Created by: Paulo, Golovattei Source: Objaverse 1.0 / Sketchfab
Cervical disc extrusion with dorsal migration in a pet rabbit: Histological slides
<p>Representative IVD fragments on histological slides after Giemsa (A: Gie) and haematoxylin eosin stain (B: HE). Fragments consist of hyaline (empty arrows) and fibrocartilage (black arrows) and present with atypical polycellular chondrocyte clusters (PLC) as well as with large mineralized areas, better seen on HE (asterisks). Scale bar for both: 510 µm.</p>
Data from: Flortaucipir PET uncovers relationships between tau and β-amyloid in aging, primary age related tauopathy, and Alzheimer disease
<p>[<sup>18</sup>F]-Flortaucipir PET is considered a good biomarker of Alzheimer's disease. However, it is unknown how flortaucipir is associated with the distribution of tau across brain regions and how these associations are influenced by β-amyloid. It is also unclear whether flortaucipir can detect tau in definite primary age-related tauopathy (PART). We identified 248 individuals at Mayo Clinic that had undergone [<sup>18</sup>F]-flortaucipir PET during life, had died, and undergone an autopsy, 239 cases of which also had β-amyloid PET. We assessed nonlinear relationships between flortaucipir uptake in nine medial temporal and cortical regions, Braak tau stage and Thal β-amyloid phase using generalized additive models. We found that flortaucipir uptake was greater with increasing tau stage in all regions. Increased uptake at low tau stages in medial temporal regions was only observed in cases with high β-amyloid phase. Flortaucipir uptake linearly increased with β-amyloid phase in medial temporal and cortical regions. The highest flortaucipir uptake occurred with high Alzheimer's disease neuropathologic change (ADNC) scores, followed by low-intermediate ADNC scores, then PART, with entorhinal cortex providing the best differentiation between groups. Flortaucipir PET had limited ability to detect PART and imaging defined PART did not correspond with pathologically defined PART. In summary, spatial patterns of flortaucipir mirrored histopathological tau distribution, were influenced by β-amyloid phase, and were useful for distinguishing different ADNC scores and PART.</p>
Resources for studying the aesthetic and diversity values of plants and pets in shaping biodiversity loss belief among urban residents
<p><span>Considering the issues of data transparency and the cost of reproduction, all data and code snippets of the study titled "From beauty to belief: The aesthetic and diversity values of plants and pets in shaping biodiversity loss belief among urban residents" are deposited here.</span></p>
Relative cerebral flow from dynamic PIB scans as an alternative for FDG scans in Alzheimer's disease PET studies
<p>In Alzheimer’s Disease (AD) dual-tracer positron emission tomography (PET) studies with 2-[<sup>18</sup>F]-fluoro-2-deoxy-D-glucose (FDG) and <sup>11</sup>C-labelled Pittsburgh Compound B (PIB) are used to assess metabolism and cerebral amyloid-β deposition, respectively. Regional cerebral metabolism and blood flow (rCBF) are closely coupled, both providing an index for neuronal function. The present study compared PIB-derived rCBF, estimated by the ratio of tracer influx in target regions relative to reference region (<em>R</em><sub>1</sub>) and early-stage PIB uptake (ePIB), to FDG scans. Fifteen PIB positive (+) patients and fifteen PIB negative (-) subjects underwent both FDG and PIB PET scans to assess the use of <em>R</em><sub>1 </sub>and ePIB as a surrogate for FDG. First, subjects were classified based on visual inspection of the PIB PET images. Then, discriminative performance (PIB+ versus PIB-) of rCBF methods were compared to normalized regional FDG uptake. Strong positive correlations were found between analyses, suggesting that PIB-derived rCBF provides information that is closely related to what can be seen on FDG scans. Yet group related differences between method’s distributions were seen as well. Also, a better correlation with FDG was found for <em>R</em><sub>1</sub> than for ePIB. Further studies are needed to validate the use of <em>R</em><sub>1</sub> as an alternative for FDG studies in clinical applications.</p> <p>The enclosed dataset refers to the work developed at the University Medical Center Groningen and consists of all the data retrieved from the PET images and from clinical assessment used in this work.</p>
Trypanosoma cruzi in Mexican Neotropical vectors and mammals: Wildlife, livestock, pets, and human population
<p><span>The aim of the present study has been to provide primary evidence of <em>Trypanosoma cruzi</em> landscape genetics in the Mexican Neotropics.</span><span> <em>T. cruzi</em> and DTU prevalence were analyzed in landscape communities of vectors, wildlife, livestock, pets, and sympatric human populations using endpoint PCR and sequencing of all relevant amplicons from mitochondrial (kDNA) and nuclear (ME, 18S, 24Sα) gene markers. Although 98% of the infected sample set (N=2963) contained single or mixed infections of DTUI (TcI, 96.2%) and TcVI (22.6%), TcIV and TcII were identified. The sensitivity of individual markers varied and was dependent on the host taxon; kDNA, ME, and 18S combined identified 95% of infections. ME genotyped 90% of vector infections, but 60% of mammals (36% wildlife), while neither 18S nor 24Sα typed more than 20% of mammal infections. Available gene fragments to identify or genotype <em>T. cruzi</em> are not universally sensitive for all landscape parasite populations, highlighting important <em>T. cruzi</em> heterogeneity among mammal reservoir taxa and triatomine species.</span></p>
Recyclage du PET par méthodes chimiques
<p>Jeu de données</p>
Survey of Dog Groomers using Pet Remedy
<p>A large scale survey was conducted to research the experience of professional groomers that us the Pet Remedy Product.</p> <p>Over ninety-five percent of the dog groomers said that they would recommend Pet Remedy to their clients, with the remaining 4.3% indicating that they were unsure whether they would. No groomers said that they would not recommend Pet Remedy to their clients.</p> <p>Eighty-seven percent of the groomers said that they would continue to use Pet Remedy in their grooming salon, with the remaining 12.9% indicating that they were unsure whether they would. Again, no groomers said that they would not continue to use Pet Remedy in their grooming salon.</p> <p>For 84% of the dogs included in the survey, the groomers felt Pet Remedy moderately or significantly improved the dog’s behaviour. Where a dog had a particular dislike, in nearly 80% of cases, the groomers felt that Pet Remedy moderately or significantly improved the response of the dog to the aspect of the grooming that they particularly disliked.</p>
Multiplexed PET data: (89Zr + 124I) mouse phantom - Doubles and Triple Coincidences - Inveon PET/CT scanner
<p>Dataset from a simultaneous 89Zr and 124I PET acquisition performed with a 3D-printed mouse phantom with the preclinical PET/CT Inveon scanner. </p> <p>It includes:</p> <p>1 ) Sinogram of Double Coincidences: With the same format as the Inveon scanner. It includes Prompt and Background . Background includes Randoms+Scatter+Promptgamma coincidences. It has already been corrected by attenuation and normalization.</p> <p>2 ) Sinogram of Triple Coincidences: With the same format as the Inveon scanner. It includes Prompt and Background . Background includes Randoms+Scatter+Promptgamma coincidences. It has already been corrected by attenuation and normalization. </p> <p>3 ) Triple Coincidences with V-LOR format (pairs of sinogram bins for each triple coincidence)</p> <p>4 ) Mask with the gaps in the sinogram</p> <p>5 ) CT image reconstructed by the scanner </p> <p> </p>
The Oxford-IIIT Pet Dataset
<p>Omkar M Parkhi and Andrea Vedaldi have created a 37 category pet dataset with roughly 200 images for each class. The images have a large variations in scale, pose and lighting. All images have an associated ground truth annotation of breed, head ROI, and pixel level trimap segmentation.The details of the categories and the number of images for each class can be found at:https://www.robots.ox.ac.uk/~vgg/data/pets/.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.