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A Pragmatic Trial of the Consult for Addiction Treatment and Care in Hospitals (CATCH) Model for Engaging Patients in Opioid Use Disorder Treatment

ClinicalTrials.gov study NCT03611335. IPD Sharing: NO. Countries: 1. Publications: 3.

A Pragmatic Trial to Determine the Benefit of Behaviorally Enhanced Exercise Incentives and Corticosteroid Injections in Osteoarthritis of the Knee Marching On for Veterans With Osteoarthritis of the

ClinicalTrials.gov study NCT05035810. IPD Sharing: NO. Countries: 1. Publications: 2.

Balance: A Pragmatic Trial of a Digital Health Intervention to Prevent Weight Gain in Primary Care

ClinicalTrials.gov study NCT03003403. IPD Sharing: NO. Countries: 1. Publications: 4.

A Pragmatic Trial of Brief CBT for Anxiety in VA Primary Care

ClinicalTrials.gov study NCT04523779. IPD Sharing: NO. Countries: 1. Publications: 4.

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis: A Pilot Feasibility Study

ClinicalTrials.gov study NCT03340805. IPD Sharing: NO. Countries: 1. Publications: 4.

Pragmatic RCT of SBIRT-PM

ClinicalTrials.gov study NCT04062214. IPD Sharing: NO. Countries: 1. Publications: 0.

Heart Failure Optimization at Home to Improve Outcomes (Hozho): A Pragmatic Clinical Trial in Navajo Nation

ClinicalTrials.gov study NCT05792085. IPD Sharing: NO. Countries: 1. Publications: 1.

COVID-19 Outpatient Pragmatic Platform Study (COPPS) - Camostat Sub-Protocol

ClinicalTrials.gov study NCT04662073. IPD Sharing: NO. Countries: 1. Publications: 1.

controlledIPD-YESFeb 2026View details →

Pragmatic Investigation of optimaL Oxygen Targets Trial

ClinicalTrials.gov study NCT03537937. IPD Sharing: YES. Countries: 1. Publications: 3.

COVID-19 Outpatient Pragmatic Platform Study (COPPS) - Master Protocol

ClinicalTrials.gov study NCT04662086. IPD Sharing: NO. Countries: 1. Publications: 3.

publicSep 2025View details →

dryad36/100

Effectiveness of screening and ultra-brief intervention for hazardous drinking in primary care: pragmatic cluster randomised controlled trial

Open the record for dataset details and reuse information.

dryad32/100

Data from: A pragmatic approach to the analysis of diets of generalist predators: the use of next-generation sequencing with no blocking probes

Predicting whether a predator is capable of affecting the dynamics of a prey species in the field implies the analysis of the complete diet of the predator, not simply rates of predation on a target taxon. Here, we employed the Ion Torrent next-generation sequencing technology to investigate the diet of a generalist arthropod predator. A complete dietary analysis requires the use of general primers, but these will also amplify the predator unless suppressed using a blocking probe. However, blocking probes can potentially block other species, particularly if they are phylogenetically close. Here, we aimed to demonstrate that enough prey sequence could be obtained without blocking probes. In communities with many predators, this approach obviates the need to design and test numerous blocking primers, thus making analysis of complex community food webs a viable proposition. We applied this approach to the analysis of predation by the linyphiid spider Oedothorax fuscus in an arable field. We obtained over two million raw reads. After discarding the low-quality and predator reads, the libraries still contained over 61 000 prey reads (3% of the raw reads; 6% of reads passing quality control). The libraries were rich in Collembola, Lepidoptera, Diptera and Nematoda. They also contained sequences derived from several spider species and from horticultural pests (aphids). Oedothorax fuscus is common in UK cereal fields, and the results showed that it is exploiting a wide range of prey. Next-generation sequencing using general primers but without blocking probes provided ample sequences for analysis of the prey range of this spider and proved to be a simple and inexpensive approach.

opencc-zeroDec 2012View details →

dryad32/100

Data from: The Fear Reduction Exercised Early (FREE) approach to management of low back pain in general practice: a pragmatic cluster-randomised controlled trial

Background: Effective and cost-effective primary care treatments for low back pain (LBP) are required to reduce the burden of the world's most disabling condition. This study aimed to compare the clinical effectiveness and cost-effectiveness of the Fear Reduction Exercised Early (FREE) approach to LBP (intervention) with usual general practitioner (GP) care (control). Methods and findings: This pragmatic, cluster-randomised controlled trial with process evaluation and parallel economic evaluation was conducted in the Hutt Valley, New Zealand. Eight general practices were randomly assigned (stratified by practice size) with a 1:1 ratio to intervention (4 practices; 34 GPs) or control group (4 practices; 29 GPs). Adults presenting to these GPs with LBP as their primary complaint were recruited. GPs in the intervention practices were trained in the FREE approach, and patients presenting to these practices received care based on the FREE approach. The FREE approach restructures LBP consultations to prioritise early identification and management of barriers to recovery. GPs in control practices did not receive specific training for this study, and patients presenting to these practices received usual care. Between 23 September 2016 and 31 July 2017, 140 eligible patients presented to intervention practices (126 enrolled) and 110 eligible patients presented to control practices (100 enrolled). Patient mean age was 46.1 years (SD 14.4), and 46% were female. The duration of LBP was less than 6 weeks in 88% of patients. Primary outcome was change from baseline in patient participant Roland Morris Disability Questionnaire (RMDQ) score at 6 months. Secondary patient outcomes included pain, satisfaction, and psychosocial indices. GP outcomes included attitudes, knowledge, confidence, and GP LBP management behaviour. There was active and passive surveillance of potential harms. Patients and outcome assessors were blind to group assignment. Analysis followed intention-to-treat principles. A total of 122 (97%) patients from 32 GPs in the intervention group and 99 (99%) patients from 25 GPs in the control group were included in the primary outcome analysis. At 6 months, the groups did not significantly differ on the primary outcome (adjusted mean RMDQ score difference 0.57, 95% CI −0.64 to 1.78; p = 0.354) or secondary patient outcomes. The RMDQ difference met the predefined criterion to indicate noninferiority. One control group participant experienced an activity-related gluteal tear, with no other adverse events recorded. Intervention group GPs had improvements in attitudes, knowledge, and confidence compared with control group GPs. Intervention group GP LBP management behaviour became more guideline concordant than the control group. In cost-effectiveness, the intervention dominated control with lower costs and higher Quality-Adjusted Life Year (QALY) gains. Limitations of this study were that although adequately powered for primary outcome assessment, the study was not powered for evaluating some employment, healthcare use, and economic outcomes. It was also not possible for research nurses (responsible for patient recruitment) to be masked on group allocation for practices. Conclusions: Findings from this study suggest that the FREE approach improves GP concordance with LBP guideline recommendations but does not improve patient recovery outcomes compared with usual care. The FREE approach may reduce unnecessary healthcare use and produce economic benefits. Work participation or health resource use should be considered for primary outcome assessment in future trials of undifferentiated LBP.

opencc-zeroSep 2019View details →

opengpl-3.0-or-laterJun 2024View details →

Software artifacts corresponding to the paper "Pragmatic Random Sampling of the Linux Kernel: Enhancing the Randomness and Correctness of the conf Tool"

<div><strong>Software artifacts corresponding to the paper "Pragmatic Random Sampling of the Linux Kernel: Enhancing the Randomness and Correctness of the conf Tool"</strong></div> <div> </div> <div> <div> <div>This repository is organized in two main folders:</div> <br> <div>1. <strong>randconfig+</strong> includes the source code of our tool randconfig+, which improves the randomness and correctness of the conf tool (a built-in Linux kernel tool for generating random samples of kernel configurations). It has two subfolders:</div>     -   <strong>source</strong>: includes the source code of randconfig+. <div>    -   <strong>bin</strong>: includes the compiled version of randconfig+.</div> <br> <div>2. <strong>experimental_validation</strong> includes the experimental validation of randconfig+ reported in the paper.</div>     -   <strong>systems</strong>: includes the 10 Linux Kernel versions analyzed in the paper. <div>    -   <strong>scripts_for_sample_generation</strong>: Bash shell scripts to generate the data.</div> <div>    -   <strong>data</strong>: includes the following data generated by the experimental validation:</div> <div>        +  Generated samples (subfolder configuration_samples). The samples are available in two formats: CSV and <a href="https://r4ds.hadley.nz/arrow">Apache Arrow</a>.</div> <div>        +   Entropies and number of distinct values per configuration option.</div> <div>        +   Data regarding the correctness of the samples and the time spent to generate them (subfolder correctness_and_runtime).</div> <div>    -   <strong>statistical_analysis</strong>: R scripts to perform the statistical analysis of the data (subfolder statistical_analysis).</div> <div>    -   <strong>plots</strong>: graphs produced from the data statistical analysis.</div> </div> </div>

Figure 26 in Pragmatic classification of the World's Salticidae (Araneae)

Figure 26. Color pattern and body shape of representatives of informal group of genera YAGINUMAELLINES and YLLENINES. YAGINUMAELLINES: A - Yaginumaella striatipes (Grube, 1861), B - Ptocasius sp ©Photos F. Murphy. YLLENINES: C - Logunyllus univittatus (Simon, 1871), D - Logunyllus vittatus (Thorell, 1875), male and female.

Figure 10 in Pragmatic classification of the World's Salticidae (Araneae)

Figure 10. Diagnostic characters of representatives of informal group of genera COLONINES. A-B - Colonus sylvanus (Hentz, 1846), C - Colonus pallidus (C. L. Koch, 1846), D - Cotinusa distincta (Peckham & Peckham, 1888), DD - misidentified " Cotinusa" (compare embolus - Fig. 7R), E - Gedea flavogularis Simon, 1902, F - Kalcerrytus excultus (Simon, 1902), G - Marma baeri Simon, 1902, H-I - Metacyrba taeniola (Hentz, 1846), J - Paramaevia poultoni Peckham & Peckham, 1901, K - Platycryptus undatus (De Geer, 1778).

Figure 7 in Pragmatic classification of the World's Salticidae (Araneae)

Figure 7. Color pattern and body shape of representatives of informal group of genera SIMAETHINES and COLONINES. SIMAETHINES: A-B - Ligurra latidens (Doleschall, 1859), C - Simaetha sp., D - Simaetha sp., E - Simaethula sp., E1 - Uroballus sp. COLONINES. K - Colonus puerperus (Hentz, 1846), L - Colonus sylvanus (Hentz, 1846), M - Cotinusa sp., N - Kalcerrytus excultus (Simon, 1902), O - Metacyrba taeniola (Hentz, 1846), P - Platycryptus undatus (De Geer, 1778), Q - Psecas euoplus Chamberlin & Ivie, 1936, R - Colonus - cleared palp, S - Xanthofreya rustica Edwards, 2015.

Figure 9 in Pragmatic classification of the World's Salticidae (Araneae)

Figure 9. Color pattern and body shape of representatives of informal group of genera NOTICIINES. A - Chinattus sp. Maddison 2015 [ID not confirmed by genitals!], B - Holoplatys planissima (L. Koch, 1879), C - Mopsolodes australensis Żabka, 1991, D - Ocrisiona leucocomis (L. Koch, 1879), E - Mopsus mormon Karsch, 1878, F - Orienticius vulpes (Grube, 1861), G - Urogelides daviesae Żabka, 2009, H - Sandalodes bipenicillatus (Keyserling, 1882), I - Ananeon howardensis Richardson 2013.

Figure 6 in Pragmatic classification of the World's Salticidae (Araneae)

Figure 6. Diagnostic characters of representatives of informal group of genera SIMAETHINES. A-B - Heratemita tenenbaumi Prószynski, Deeleman-Reinhold, 2012, C - Iona nigrovittata [?] (Keyserling, 1882), D - Irura mandarina Żabka1985, E - Irura prima (Żabka. 1985), F - Ligurra latidens (Doleschall, 1859), G - Simaetha thoracica Thorell, 1881, H - Poecilorchestes logunovi Prószynski & Deeleman-Reinhold, 2013, I - Simaethula sp. Davies Todd, Żabka1989, J - Simaethulina castanea Wesolowska 2012, K - Stergusa incerta Prószynski, Deeleman-Reinhold, 2010, L - Stertinius onoi Prószynski, Deeleman-Reinhold 2010.

Figure 1A in Pragmatic classification of the World's Salticidae (Araneae)

Figure 1A. Convenient and most reliable morphological diagnostic characters in Salticidae. A, C, E, I-L - Psenuc sp., D - Psenuc courti Żabka, 1993, F - Afraflacilla reiskindi (Prószyński, 1992), G - Afraflacilla philippinensis (Prószyński, 1992), H - Psenuc vesporum (Proszynski 1992), A-D. Genitalic charaters: A-B - palp in standard position, C - epigyne, external view, D - internal structure of epigyne: note copulatory openings, ducts, spermathecae (with pheromone exuding pore, developed here duct like, pockets), E-H - morphological characters of this particular genus, E – lateral subocular row of stridulatory bristles on tubercles, F - modified leg I, G - variation in shape and spination of tibia I, left and right in the same specimens, upper male, lower - female, H - male and female variation in tibia I in another species, I-K - body shape and color pattern in male, L - the same in female.