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127
datasets available to search
ShareScore release 0.9.0
Dataset results
127 results for “spatiotemporal dynamic”
Data from: Spatiotemporal dynamics and genome-wide association analysis of desiccation tolerance in Drosophila melanogaster
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Data from: Two forms of asynchronous release with distinctive spatiotemporal dynamics in central synapses
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Dataset for analysing spatiotemporal dynamics of large carnivores in Kasungu National Park, Malawi
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Data from: Spatiotemporal dynamics of Puumala hantavirus associated with its rodent host, Myodes glareolus
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Spatiotemporal connectivity dynamics in spatially structured populations
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Predicting Hydrophobicity by Learning Spatiotemporal Features of Interfacial Water Structure: Combining Molecular Dynamics Simulations with Convolutional Neural Networks
<p>Files for reproducing results from Kelkar et al. (JPCB 2020) - Predicting Hydrophobicity by Learning Spatiotemporal Features of Interfacial Water Structure: Combining Molecular Dynamics Simulations with Convolutional Neural Networks</p> <p> </p> <p>This folder contains simulations starter files and also plug-and-play datasets to test ML algorithms on molecular dynamics (MD) simulation data.</p> <p> </p> <p>All analysis scripts can also be found on GitLab on this link: https://gitlab.com/atharva-kelkar/kelkar_et_al_jpcb_2020</p>
Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing
<p>Keratinocytes, the predominant cell type of the epidermis, migrate to reinstate the epithelial barrier during wound healing. Mechanical cues are known to regulate keratinocyte re-epithelization and wound healing however, the underlying molecular transducers and biophysical mechanisms remain elusive. Here, we show through molecular, cellular and organismal studies that the mechanically-activated ion channel PIEZO1 regulates keratinocyte migration and wound healing. Epidermal-specific Piezo1 knockout mice exhibited faster wound closure while gain-of-function mice displayed slower wound closure compared to littermate controls. By imaging the spatiotemporal localization dynamics of endogenous PIEZO1 channels we find that channel enrichment at some regions of the wound edge induces a localized cellular retraction that slows keratinocyte collective migration. In migrating single keratinocytes, PIEZO1 is enriched at the rear of the cell, where maximal retraction occurs, and we find that chemical activation of PIEZO1 enhances retraction during single as well as collective migration. Our findings uncover novel molecular mechanisms underlying single and collective keratinocyte migration that may suggest a potential pharmacological target for wound treatment. More broadly, we show that nanoscale spatiotemporal dynamics of Piezo1 channels can control tissue-scale events, a finding with implications beyond wound healing to processes as diverse as development, homeostasis, disease and repair.</p>
Data from: Spatial and spatiotemporal variation in metapopulation structure affects population dynamics in a passively dispersing arthropod
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Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing
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Data from: Live imaging of symbiosis: spatiotemporal infection dynamics of GFP-labelled Burkholderia symbiont in the bean bug Riptortus pedestris
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Spatiotemporal molecular and cellular dynamics of intratelencephalic neurons in mouse prefrontal cortex during postnatal development
GEO Series GSE298260. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Spatiotemporal dynamics of the cardioimmune niche during lesion repair [spatial]
GEO Series GSE280376. Mus musculus. 8 samples. Type: Other.
Single-cell DNA replication profiling identifies spatiotemporal developmental dynamics of chromosome organization
GEO Series GSE113985. Mus musculus. 960 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other.
Distinct spatiotemporal dynamics of CD8+ T cell-derived cytokines in the tumor microenvironment (6489)
GEO Series GSE220733. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Nup93 modulates spatiotemporal dynamics and function of the HOXA gene cluster during differentiation
GEO Series GSE130656. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Spatiotemporal single-cell analysis decodes cellular dynamics underlying different responses to immunotherapy in Colorectal Cancer
GEO Series GSE236581. Homo sapiens. 169 samples. Type: Other.
Decoding Spatiotemporal Transcriptional Dynamics and Epithelial Fibroblast Crosstalk during Gastroesophageal Junction Development through Single Cell Analysis (Tissue-scRNAseq)
GEO Series GSE227412. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Distinct spatiotemporal dynamics of CD8+ T cell-derived cytokines in the tumor microenvironment (5310)
GEO Series GSE220730. Homo sapiens. 5 samples. Type: Expression profiling by high throughput sequencing.
Distinct spatiotemporal dynamics of CD8+ T cell-derived cytokines in the tumor microenvironment (7296)
GEO Series GSE246621. Mus musculus. 29 samples. Type: Expression profiling by high throughput sequencing.
Spatiotemporal transcriptional dynamics of the cycling mouse oviduct
GEO Series GSE164718. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.