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188 results for “swine”
Immunogenicity, Safety and Tolerability of Two Doses of Adjuvanted and Non-adjuvanted Swine Origin A/H1N1 Monovalent Influenza Vaccine (Egg-Derived) in Healthy Subjects From 6 Months to 17 Years of Ag
ClinicalTrials.gov study NCT00971542. IPD Sharing: Not stated. Countries: 5. Publications: 1.
Zoonotic Influenza Infections of Swine Origin at Ohio Agricultural Fairs
ClinicalTrials.gov study NCT02124096. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Observational Safety and Effectiveness Study of Adjuvanted Swine Origin A (H1N1) Pandemic Subunit Egg Derived Vaccine
ClinicalTrials.gov study NCT01101074. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Immunogenicity, Safety and Tolerability of Two Doses of Adjuvanted and Non-adjuvanted Swine Origin A/H1N1 Monovalent Influenza Vaccine in Healthy Subjects 18 or More Years of Age
ClinicalTrials.gov study NCT00971906. IPD Sharing: Not stated. Countries: 3. Publications: 1.
Swine Flu (Novel Influenza A H1N1) Vaccine Study
ClinicalTrials.gov study NCT00980850. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Data from: Simulating the distribution of individual livestock farms and their populations in the united states: an example using domestic swine (Sus scrofa domesticus) farms
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Ecological drivers of African swine fever virus persistence in wild boar populations: insight for control
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Data from: Effects of the selective stretch-activated channel blocker GsMtx4 on stretch-induced changes in refractoriness in isolated rat hearts and on ventricular premature beats and arrhythmias after coronary occlusion in swine
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Data from: Origins of the 2009 H1N1 influenza pandemic in swine in Mexico
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Pig swine intestine culturomics sequences
<p>The culturomics sequences here presented are part of the manuscript entitled "<em>Salmonella enterica</em> serovar Typhimurium Temporally Modulates the Enteric Microbiota and Host Responses to Overcome Colonization Resistance in Swine".</p> <p>The sequence headers in the FASTA file contain the following information:</p> <ul> <li>Species assigned (might include strain and GenBank accession number)</li> <li>Treatment</li> <li>Isolation method / Environment / Tissue</li> <li>Animal number identifier</li> </ul>
Data from: Validation of perfusion quantification with 3D gradient echo dynamic contrast-enhanced magnetic resonance imaging using a blood pool contrast agent in skeletal swine muscle
The purpose of our study was to validate perfusion quantification in a low-perfused tissue by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) with shared k-space sampling using a blood pool contrast agent. Perfusion measurements were performed in a total of seven female pigs. An ultrasonic Doppler probe was attached to the right femoral artery to determine total flow in the hind leg musculature. The femoral artery was catheterized for continuous local administration of adenosine to increase blood flow up to four times the baseline level. Three different stable perfusion levels were induced. The MR protocol included a 3D gradient-echo sequence with a temporal resolution of approximately 1.5 seconds. Before each dynamic sequence, static MR images were acquired with flip angles of 5°, 10°, 20°, and 30°. Both static and dynamic images were used to generate relaxation rate and baseline magnetization maps with a flip angle method. 0.1 mL/kg body weight of blood pool contrast medium was injected via a central venous catheter at a flow rate of 5 mL/s. The right hind leg was segmented in 3D into medial, cranial, lateral, and pelvic thigh muscles, lower leg, bones, skin, and fat. The arterial input function (AIF) was measured in the aorta. Perfusion of the different anatomic regions was calculated using a one- and a two-compartment model with delay- and dispersion-corrected AIFs. The F-test for model comparison was used to decide whether to use the results of the one- or two-compartment model fit. Total flow was calculated by integrating volume-weighted perfusion values over the whole measured region. The resulting values of delay, dispersion, blood volume, mean transit time, and flow were all in physiologically and physically reasonable ranges. In 107 of 160 ROIs, the blood signal was separated, using a two-compartment model, into a capillary and an arteriolar signal contribution, decided by the F-test. Overall flow in hind leg muscles, as measured by the ultrasound probe, highly correlated with total flow determined by MRI, R = 0.89 and P = 10−7. Linear regression yielded a slope of 1.2 and a y-axis intercept of 259 mL/min. The mean total volume of the investigated muscle tissue corresponds to an offset perfusion of 4.7mL/(min ⋅ 100cm3). The DCE-MRI technique presented here uses a blood pool contrast medium in combination with a two-compartment tracer kinetic model and allows absolute quantification of low-perfused non-cerebral organs such as muscles.
Lemna minor Cultivation for Treating Swine Manure and Providing Micronutrients for Animal Feed
<p>The potential of Lemna minor to valorise agricultural wastewater into a protein-rich feed component to meet the growing demand for animal feed protein and reduce the excess of nutrients in certain European regions was investigated. Three pilot-scale systems were monitored for nine weeks under outdoor conditions in Flanders. The systems were fed with a mixture of the liquid fraction and the biological effluent of a swine manure treatment system diluted with rainwater in order that the weekly N and P addition was equal to the N and P removal by the system. The design tested the accumulation of elements in a continuous recirculation system. Potassium, Cl, S, Ca, and Mg were abundantly available in the swine manure wastewaters and tended to accumulate, being a possible cause of concern for long-operating recirculation systems. The harvested duckweed was characterised for its mineral composition and protein content. In animal husbandry, trace elements are specifically added to animal feed as micronutrients and, thus, feedstuffs biofortified with essential trace elements can provide added value. Duckweed grown on the tested mixture of swine manure waste streams could be considered as a source of Mn, Zn, and Fe for swine feed, while it is not a source of Cu for swine feed. Moreover, it was observed that As, Cd, and Pb content were below the limits of the feed Directive 2002/32/EC in the duckweed grown on the tested medium. Overall, these results demonstrate that duckweed can effectively remove nutrients from agriculture wastewaters in a recirculated system while producing a feed source with a protein content of 35% DM.</p>
Supplementary Figure 1. Comparison of diagnostic sensitivity of African swine fever virus (ASFV) real-time PCR kits using artificially spiked samples (ASSs)
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African swine fever virus E120R protein inhibits interferon-β production by interacting with IRF3 to block its activation
<p><span><span>African swine fever is a devastating disease of swine caused by African swine fever virus (ASFV). The pathogenesis of the disease remains largely unknown, leaving the uncontrolled spreading of the disease in many countries and regions. Here, we identified the E120R, a structural protein of ASFV, as a key virulent factor and late phase expression protein of the virus. E120R revealed an activity to suppress host antiviral response through blocking IFN-β production, and the 72-73 amino acid sites in the C-terminal domain were essential for this function. E120R interacted with the interferon regulatory factor 3 (IRF3) and interfered with the recruitment of IRF3 to TBK1, which in turn suppressed IRF3 phosphorylation, decreasing interferon production. The recombinant mutant ASFV was further constructed to confirm the claimed mechanism. The ASFV lacking the complete E120R region could not be rescued, whereas the virus could tolerate the deletion of the 72nd and 73rd residuals in the E120R (ASFV E120R-Δ72-73aa). ASFV E120R with the two amino acids deletion failed to interact with IRF3 during ASFV E120R-Δ72-73aa infection, and the viral infection highly activated IRF3 phosphorylation and induced more robust type I interferon production in comparison with its parental ASFV. An unbiased transcriptome-wide analysis of gene expression also confirmed that a considerably higher level of ISGs was detected in ASFV E120R-Δ72-73aa-infected porcine alveolar macrophages (PAMs) than that in the wildtype ASFV-infected PAMs. Together, our findings found a novel mechanism evolved by ASFV to inhibit host antiviral response and provide a new target for guiding the development of ASFV live-attenuated vaccine.</span></span></p>
Assessment of animal diseases caused by bacteria resistant to antimicrobials: Swine - Appendix B: Excel file with all data extracted
<p>Information on all the full-text studies that were assessed, including the reason for exclusion for those that were excluded at the full-text screening and the data extracted from the included studies, can be consulted here. </p> <p>The extensive literature review was carried out by the University of Copenhagen under the contract OC/EFSA/ALPHA/2020/02 – LOT 1 (https://ted.europa.eu/udl?uri=TED:NOTICE:457654-2020:TEXT:EN:HTML)</p>
Safety and Immunogenicity of A/H1N1-SOIV (Swine Flu) Vaccine With and Without Adjuvant in Children (3 to < 9 Years)
ClinicalTrials.gov study NCT00972816. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Safety and Immunogenicity of A/H1N1-SOIV (Swine Flu) Vaccine With and Without Adjuvant in Non-Elderly and Elderly Adults
ClinicalTrials.gov study NCT00973349. IPD Sharing: Not stated. Countries: 2. Publications: 0.
African swine fever virus E120R protein inhibits interferon-β production by interacting with IRF3 to block its activation
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Data from: Validation of perfusion quantification with 3D gradient echo dynamic contrast-enhanced magnetic resonance imaging using a blood pool contrast agent in skeletal swine muscle
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Data from: Intracoronary delivery of human mesenchymal/stromal stem cells: insights from coronary microcirculation invasive assessment in a swine model
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Allen Brain Atlas
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.