Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
1,274
datasets available to search
ShareScore release 0.9.0
Dataset results
1,274 results for “Disease Model”
Developing a novel human adult kidney organoid model to recapitulate injury-associated regeneration and polycystic kidney disease
GEO Series GSE242023. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Adverse proinflammatory responses in the kidney after FGF23 administration in murine kidney disease models
GEO Series GSE272289. Mus musculus. 38 samples. Type: Expression profiling by high throughput sequencing.
Beyond acid suppression: Novel therapeutic targets for gastro-esophageal reflux disease based on a murine model (esophageal tissue)
GEO Series GSE63401. Rattus norvegicus. 20 samples. Type: Expression profiling by array.
Transcriptional dysregulation in a primary cortical neuron model of Huntington's disease
GEO Series GSE115522. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
RNA-sequencing uncovers transcriptomic changes induced by a multiblock thermogelling polymer on healthy and disease-modeled retinal pigment epithelial cells
GEO Series GSE176513. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Tumor necrosis factor activation variability in minimal change disease and focal segmental glomerulosclerosis: a model for precision nephrology
GEO Series GSE213030. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Bladder cancer organoids as a functional system to model different disease stages and therapy response
GEO Series GSE217956. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Effect of estrogen receptor alpha (ERα) signaling in dendritic cells in modulating autoimmune disease phenotype in animal model of Multiple Sclerosis
GEO Series GSE215238. Mus musculus. 9 samples. Type: Expression profiling by high throughput sequencing.
A human liver cell-based system modeling a clinical prognostic liver signature combined with single-cell RNA-Seq for discovery of liver disease therapeutics
GEO Series GSE173671. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
PANDORA-seq uncovers sensitive mitochondrial small RNA alterations associated with increased lysosome activity in an Alzheimer’s Disease Mouse Model
GEO Series GSE277483. Mus musculus. 30 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Pharmacologic C5aR1 antagonism in the Arctic mouse model of Alzheimer’s disease modifies microglial polarization and astrocyte signaling
GEO Series GSE240950. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Deletion of Abi3 gene locus exacerbates neuropathological features of Alzheimer’s disease in a mouse model of Aβ amyloidosis
GEO Series GSE175389. Mus musculus. 11 samples. Type: Expression profiling by high throughput sequencing.
Exploring MHC Class II I-Ab Blockade as a Potential Treatment for Sjögren’s Disease in the Mouse Model
GEO Series GSE290595. Mus musculus. 8 samples. Type: Other.
Screening for genes that promote copper toxicity in a cell model of Wilson disease
GEO Series GSE260454. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease
GEO Series GSE236012. Rattus norvegicus. 18 samples. Type: Expression profiling by high throughput sequencing.
Modeling SMAD2 mutations in iPSCs provides insights into cardiovascular disease pathogenesis [RNA-seq]
GEO Series GSE280689. Homo sapiens. 21 samples. Type: Expression profiling by high throughput sequencing.
Gamma oscillations attenuate amyloid pathology and trigger a protective microglia response in a mouse model of Alzheimer's disease
GEO Series GSE77471. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Loss of Snhg5 disrupts cell-cycle regulation without altering cystogenesis in a mouse model of polycystic kidney disease.
GEO Series GSE300255. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Development of novel in vitro human alveolar epithelial cell models to study distal lung biology and disease [bulk RNA-seq]
GEO Series GSE164513. Homo sapiens. 17 samples. Type: Expression profiling by high throughput sequencing.
Sinus venosus adaptation models prolonged cardiovascular disease and reveals insights into evolutionary transitions of the vertebrate heart
GEO Series GSE195549. Ciona robusta. 6 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.